Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:9294252-9300568[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0014 0.08 13.2 0.4 1 23 149 171 149 171 0.97

2 14 3.5e-05 0.002 18.2 3.8 1 23 380 402 380 402 0.98

3 14 0.97 56 4.2 1.2 1 23 408 431 408 432 0.93

4 14 0.044 2.5 8.4 0.6 1 23 449 472 449 472 0.91

5 14 0.0011 0.066 13.4 1.9 3 23 741 761 740 761 0.92

6 14 0.046 2.6 8.4 1.4 1 23 767 790 767 790 0.98

7 14 2.5 1.4e+02 2.9 1.2 2 23 827 848 826 849 0.92

8 14 0.0024 0.14 12.4 0.6 1 23 870 893 870 893 0.97

9 14 0.00071 0.041 14.1 0.2 1 23 1098 1121 1098 1121 0.93

10 14 0.0083 0.48 10.7 5.2 1 23 1133 1155 1133 1155 0.98

11 14 3.1e-06 0.00018 21.5 1.0 2 23 1161 1183 1160 1183 0.97

12 14 0.012 0.67 10.3 4.0 2 23 1190 1214 1189 1214 0.93

13 14 0.13 7.8 6.9 2.9 1 23 1219 1241 1219 1241 0.96

14 14 0.014 0.78 10.1 0.5 1 23 1247 1270 1247 1270 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0014	0.08	13.2	0.4	1	23	149	171	149	171	0.97
2	14	3.5e-05	0.002	18.2	3.8	1	23	380	402	380	402	0.98
3	14	0.97	56	4.2	1.2	1	23	408	431	408	432	0.93
4	14	0.044	2.5	8.4	0.6	1	23	449	472	449	472	0.91
5	14	0.0011	0.066	13.4	1.9	3	23	741	761	740	761	0.92
6	14	0.046	2.6	8.4	1.4	1	23	767	790	767	790	0.98
7	14	2.5	1.4e+02	2.9	1.2	2	23	827	848	826	849	0.92
8	14	0.0024	0.14	12.4	0.6	1	23	870	893	870	893	0.97
9	14	0.00071	0.041	14.1	0.2	1	23	1098	1121	1098	1121	0.93
10	14	0.0083	0.48	10.7	5.2	1	23	1133	1155	1133	1155	0.98
11	14	3.1e-06	0.00018	21.5	1.0	2	23	1161	1183	1160	1183	0.97
12	14	0.012	0.67	10.3	4.0	2	23	1190	1214	1189	1214	0.93
13	14	0.13	7.8	6.9	2.9	1	23	1219	1241	1219	1241	0.96
14	14	0.014	0.78	10.1	0.5	1	23	1247	1270	1247	1270	0.94

Sequence Information

Coding Sequence: ATGGCGCTGAACAAGAGGAACAGCTCGCACTCGGACGCAATTTCGGGCGCCGAGGTGGACTACAAGTTTTCGTGTCGCTGCTGCCTGAAGACGGATGTGGAGTACCTCAAACTGGACTCGGTGGTGGTGGCGCGCAGTCTGGATCCGGCGGACACATCGGACAAGATCCCCCTGCTCCGGTGCCTGCTCTTCTGCGTGAGCGCCGAAAATGCCCCCGAGCTGCCGCAGTACATCTGTATCGAGTGCAGCAAGAGCCTCCAGGTGGCCTACTACTTCCTTAAGAACGCTCTGCGTGCCCACGAGATCCTGTGTCGCAAACTGTGTCCCAAGCGGGGCCAAAGGAGACTTAATGGCTCTCTGGTCCAGGAGCCGGAGAAGAAACCCGGAAACCCAGTAGTCCCTCAAGAACTGGAGACGGAGATGAAGCCGTTGAAAACCATGCGGCACGAGTGCCAGGTGTGCGGAGTGGTGGTCTACAATCGCCTGGAGCTCAAGCAGCACATACGCCAACATGCAGAGGGTCTTTCGTACAACTGCAAGATGTGCAGCTTCACCACGCTGAAACAGCGCGTACTGCTGGAGCATTATATCAACATTCATGGCCTGTCCACTGGCCAGGCGGAGGAGCATGTCAAAAACAAGGACTTGCCGGCGCCCAGATATGAAGAACCCAAGCCGGTGTGCACGCTGGAGGACATGGAGCTGCTAATACCCACTGTTCTGACGCCAGATGACTACGCGCAGCCACAGCTGCAGCCGCATATCGATTCCGAGCAGCTGCGCGACATTGAGCAGCAGCTGGCCGTCAGCATGGGCGAAACGGTGCCCGGAGTAGACACTCTCACTTCCACCTTACCGCCCATGGACACGCCCAATGTGAGCATAGGGACCGAGTACCTGGTCCTGCCCGATGGCTCGCTGCAGCAGGTCAATGGAAGCGGCGTGGTCATAGAGTATATCGATGACAGCAAGCCAAACAACGCCTCCAATGTCAATATCAGCCTACAAAATCTTTTGGGTGTCAATGAGCAGAGTGTACCGATGGATATCGATGTCAGCGAGCTGATTGTGGAGGATGTTATGCCGCAGCCAAGAGCCAGGCCAAAGCCAACAGCTGGCGGATCGCCCGCTTACAAACACAAGTGCAAAATATGTCCGAAAACATTTTCCACTGTGACACGCCTCAAATCTCACCAATTGACACACAGCAATTTGCCCAAGTTCTTCTGCGATCAGTGCGACTATTACTCGCTGCGCAGCGCCGATCTCATAGAGCATTACAAGATGGTCCACCATCGGTCTGATGAAAACGGCAAGAGTGACAAAGAGCCGGATTCACGTGTCTTCTCGTGCGACATGTGCCTCTTCGAGACGCGCAACGCCAGTCAGCTGCGAACGCACTACACGGATGGGCACAGGGTCCAGCCTACGGAGGTGCAGCTGCGTCCCAGTTGGTCCAGTGAGGCGGAAGCTAGCATTCTCCAAGCTCCAGCTTCGAGTGGCGTTGCCCCCAAGCAGCTGCCTTCGGTCAGGAAACCAGATCACAACGACATCCCAATTGGCATTAAATATCCGCCAGTTGTTGTGGAACAGCAGGTACCAATGCAGCAGCCGGCGCCGATGGCCACCACATCCACGACCATCACAGAATCGGGCGAAATCAACGTGTTGGTGGATGCCACGCCGCTTTTCTATGCGGCAACCGCCAGTAGCACAGCTGTAGCGACGAACCCGCTGCCTGTCCCAATGACACCTGTGGTGGACTCAACCGGAGAAGCTAACAGCAATGCATTTGGAATCTTTCCCGAAATCTCAGACGGCACTCTGCCAGTGAACGAAGCCGTTCAGCAAGCCGTTCAGCAAGTGGCAGCCAATACATCGAACATTTCGATCTTTGGCGACATGCAGGATTTCATTGACAACACCGATGTGGCTGCAATTTGCACCATACCCGCTGACGATATGCCCGTGGTGGATGGCGATGACATTGTGATTGATAATAACAATATCAGTCTGGACTTTGATGCCGAGAACTTGTTCGAGGACttcgacgaggaggaggatgcGGTGGgcgaagaggaggaggaggaggaggcggacAACGATGACGAGAATGACAACAACGATGCTGCCACAGATCAGAATCTGCTGCTAACCAGTGACGATGATGATGTCGACGACTTTGACGACGAGCAATCGAAGCATTTGCAGAAGCCCTACTGCATATACTGCAACAAGAAGTTTACCAGCCAGTATAAGTTTGAGAACCACATGTTTGTCCATCGGGGTCTGGCCCCCTATCGCTGCGAGCTGTGTACCAATCTGTACAACATGAAGCGTCTGCTGATCAGGCATTACAAAACTGTGCACAAGCGAATGCCCACGAGAGACATGGTCCAGGCCAAGGGCGATAAGGTTTCAGTAGCCCGCACTAACATCGAAAAACTATATCTTGGCAAGATGAAGAAACCAATGCTCATGTGCGCTAAATGTCCATTCGAGTGCGAATCAGATGCGGATATGCGGCAGCATCTAAATGCCCACCACGGCATTAATGATGGCGtttCCATACATGCCAACGAGGTGTTTATTATACGCAAATTACCCTTTGAATGCCCGCGCTGCATTCGATCTTTTGCGGCCAAAAGCACCCTCAGCCGCCACCTGCAGCGCAGCCATTTAGTGGACACTATTATAGAGATGCAAACGCCACAATCGGTGGAAAGCACCACTGTAACCTTGACCACATCGTCGTCCACAAGTTGTGGACCAGAGAATCCGGTCTTTGAGGAAAACAAACAGATTGAGATGATGCAGACGGACGGTGGGGCTGAGATGATGACGGCGGCGGCTTCAGGCAATGGCGGTGGCAATGAAGTAGCTGGCAAAGATGATGGATCGGGAATAAAAATGGAACCGGCAGTGCCAGAGGAAGAACTAGATCCAGTGACATTGGACGCAGCCACGGCAGTGACGACAACGGCTATAGCAGCAGCAAtaacagcggcagcagcagcggcagctaCATCCTCCGAATCGCCCATCACAACGACAGCCTCATCGTCGACCAACCTCTTTCCCACGCCCACACCGTTTGATTACGACTATGACTTCATGGGAGATGCAGCCCAGCGATCCACGCCCAATTCCCATGCCATGCCCAAAGCCATAACGAATGCCCCACCAAGCAGTCATCTCAACGGAAGCGACAAACTATTGACCACCGCCGCCCTGGCTGCATCGCCAGTGAAGGGTTTGCGCTCCAACTCCCGTCTGCTTCGAACTTCCACTTACGCATGCAAGATATGCAACAAGACTTTCGACGAACTGGGCAAGCTGGTTAAGCACGAGATGGAGCTGCACTCCAATACGGAGCCATCGCGGTGGGGCTACCAACACAAGTGTTCAATCTGCAATACGACGTACCGAACGCTCACTCTGCTCAAGTTCCATATGAAACGGCACGGCGCCCGGAAATCACAGTGCAAGCTCTGCCCCAAAACCTTTGTGAACAACGCTGAGCTGGAGCGGCACACGAAGACAAAGCACGGGAAGGAGAAGACGCTGCGGTGCACGTTTGATGGATGCCGGAAGACGTTCGGTTTCAAGCATCATTTGGTGCGCCATCAGAACGCAATGCACTTGGACGGGCGGCATATATGCTCCGTCTGCAACAAGGATATGCAATCCAGTCTGCATTTGAGGAATCACATGAGCGTGCACAAGGGCATGGCGACCTACAAGTGTCCCAAGTGCGAACGTTCCTACTTGCGGCGTGGAAGACTCACAAGCCATGTTCTCTTGATTCACAATATCCGGCTGACCAAAGAAGAGATAGCTGACATCTCTGCACAGTCTACGGACCCTAACAACTCTACAGATTTGAATGAAACACCTCCCAGTTGCAATAAGGATGTGGATGGGGAAAAGGAAATCAAGGAGGAGACCGCAGCTGCATGCAATAATTCCAAGTAG
Protein Sequence: MALNKRNSSHSDAISGAEVDYKFSCRCCLKTDVEYLKLDSVVVARSLDPADTSDKIPLLRCLLFCVSAENAPELPQYICIECSKSLQVAYYFLKNALRAHEILCRKLCPKRGQRRLNGSLVQEPEKKPGNPVVPQELETEMKPLKTMRHECQVCGVVVYNRLELKQHIRQHAEGLSYNCKMCSFTTLKQRVLLEHYINIHGLSTGQAEEHVKNKDLPAPRYEEPKPVCTLEDMELLIPTVLTPDDYAQPQLQPHIDSEQLRDIEQQLAVSMGETVPGVDTLTSTLPPMDTPNVSIGTEYLVLPDGSLQQVNGSGVVIEYIDDSKPNNASNVNISLQNLLGVNEQSVPMDIDVSELIVEDVMPQPRARPKPTAGGSPAYKHKCKICPKTFSTVTRLKSHQLTHSNLPKFFCDQCDYYSLRSADLIEHYKMVHHRSDENGKSDKEPDSRVFSCDMCLFETRNASQLRTHYTDGHRVQPTEVQLRPSWSSEAEASILQAPASSGVAPKQLPSVRKPDHNDIPIGIKYPPVVVEQQVPMQQPAPMATTSTTITESGEINVLVDATPLFYAATASSTAVATNPLPVPMTPVVDSTGEANSNAFGIFPEISDGTLPVNEAVQQAVQQVAANTSNISIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFDEEEDAVGEEEEEEEADNDDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTNIEKLYLGKMKKPMLMCAKCPFECESDADMRQHLNAHHGINDGVSIHANEVFIIRKLPFECPRCIRSFAAKSTLSRHLQRSHLVDTIIEMQTPQSVESTTVTLTTSSSTSCGPENPVFEENKQIEMMQTDGGAEMMTAAASGNGGGNEVAGKDDGSGIKMEPAVPEEELDPVTLDAATAVTTTAIAAAITAAAAAAATSSESPITTTASSSTNLFPTPTPFDYDYDFMGDAAQRSTPNSHAMPKAITNAPPSSHLNGSDKLLTTAALAASPVKGLRSNSRLLRTSTYACKICNKTFDELGKLVKHEMELHSNTEPSRWGYQHKCSICNTTYRTLTLLKFHMKRHGARKSQCKLCPKTFVNNAELERHTKTKHGKEKTLRCTFDGCRKTFGFKHHLVRHQNAMHLDGRHICSVCNKDMQSSLHLRNHMSVHKGMATYKCPKCERSYLRRGRLTSHVLLIHNIRLTKEEIADISAQSTDPNNSTDLNETPPSCNKDVDGEKEIKEETAAACNNSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605810;
90% Identity: iTF_00605061;
80% Identity: -