Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:7490390-7495308[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00024 0.014 15.6 5.2 1 23 738 760 738 760 0.97

2 7 0.0054 0.31 11.3 0.3 1 23 766 788 766 788 0.97

3 7 0.00043 0.025 14.8 0.9 1 23 794 816 794 816 0.99

4 7 5.1e-07 2.9e-05 24.0 0.5 1 23 822 844 822 844 0.99

5 7 2.9e-06 0.00017 21.6 0.4 1 23 850 872 850 872 0.99

6 7 3.1e-06 0.00018 21.5 0.6 2 23 879 900 878 900 0.97

7 7 0.00071 0.041 14.1 0.4 1 23 906 929 906 929 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00024	0.014	15.6	5.2	1	23	738	760	738	760	0.97
2	7	0.0054	0.31	11.3	0.3	1	23	766	788	766	788	0.97
3	7	0.00043	0.025	14.8	0.9	1	23	794	816	794	816	0.99
4	7	5.1e-07	2.9e-05	24.0	0.5	1	23	822	844	822	844	0.99
5	7	2.9e-06	0.00017	21.6	0.4	1	23	850	872	850	872	0.99
6	7	3.1e-06	0.00018	21.5	0.6	2	23	879	900	878	900	0.97
7	7	0.00071	0.041	14.1	0.4	1	23	906	929	906	929	0.96

Sequence Information

Coding Sequence: ATGTCAGACATGCTGAAAATGGCAAATGTTGCAAATCCCAATCCGCTGCAAACAATGAAGAAAACAAACGGCGACGACGGCGAGTCCGATGAGTCTGAAATGGAAGAGGAGGAGGGAGAGGaagacgaggaggaggaggaggacgaggacgatCTGCCGGACGATGTGGTGCTCCAAATCGACAGCGAGGACGAGGCGGAGCTGGAAGCGCAGCGCATCCGCCTAGTGGAAGAGGAAGCAGCAAAGACAACAAAAAAGGCAGAGAAAGAGCaggagcagcaacaacaagaaccaCAGCAAGCGCAGGTCAGTAACGGTAAAGCAGAGCAGCTGGGGGAAACTGgaaaatccaaaaacaaaaacaaacgtGGAAGGCCCAAGCGCAGGGCTTCCACTAGTTCGCAGGCTTCCAGTGCGTCCATCGCTTCCCTGGTTTCCAGCGGATCCCTGGTGGCCGCCGAAGTTCTGGCGGATGAAAAGTCACGCCGCTTCATCTACAGCTGTTCGAGCTGCACTCACCACTACGCCGACAGCCTGATCCTCTCCAGACACTTCCAGCAGCAGCATGCCGAGAAGCCGAAGAGGAAGCGCGGTAAGGCCAAGGCTTCCCTTGAAGAAACACTGGTTACTCCTTCCCTGAACCTTGACCTGCTGGAAATAGGCCACCTCAAGCCCTGTGCCCAGTTGCTCGTCCAGGGGGAGTCCCTGCTGCAGCTGTGCCTCGCCTGCAACTCGCAGTTTGTGGACGAAGTACGCTTTCAGGAGCATCTCAGCCAGCAGCATGGTTACTTCAAGCTGCTGGTGCCCAAGGAGGAACCCAGCGATCTCCCCCCGCAGGCCATGGTCACCATTCCGGGGGCTCTGGTCAAAGGCAATTCCCAGCTCCAGCTGCCCATTCCAGCACCGGAAACTCCCCCACCCGAGCAGGATGCCAAGGAAACCCCACCAAGTACCGTGTCCAACGACAAGGAGGATCTGGAGATGATCAACGCCATGGTGGCGGAAATTGCCGCTGAGCGGGTGAAGAAAACCAGCAGTCCCAAGGTCAGCAAGATGATCATCAAGCTGCCCACGACCAACAAAAGGGGCAGAAAGCGAACCAAGCCAGAGAAAATCAGGGACGGAAAGGTCAAGTCGGAGAAGAGCAGGGAGAGGAAGCAGGAGAAGCCGGAGAAGAAGAAAAAATTGGACAAAAAGGAGGAAAAGCTGTTGGATTCGGAGCCGAGCAAACCGAATGATGAGGCGAAACAGCAGAAGGAAAAAACTGAAAACGGGTTGCAGCAGCCGGTGACGATTGGTATTGAGCAGTCACAGCCGGATAAAGTTGAAAATGACCAACCGAAACCGGAGGAATCAGAGAAAGAAAGTCATCAGTTGCCTAAAGAAGCTGTAGCAGATACACAGTTCCCAGAGAAACCTGAGGAGCAGGCCCTCGAGAAGCCTGTTAGCGAAGGGCAGTCGCCGGAGAAAGATTCAATGGAGCAGCAGTCGGTGACAAAAGAAAATGATAAGTCACTAGAGAGGTCTCGAACGGATCAGCAATCGCTTGAGAAAGTTTTGAAGGAGCAGCAGTCACTGGAGAAGTTTGGCAAGGAAAAGCAATTGGTGGATGAAGCTGTCAAGGAGAATCAGCCGCTGCAGAAAGACTCACAAGAGCCCGAGCGGGAAGAAAAAGATGACACGGAGACACACAAGCTTGTCATTCCTAATGAAGATATTCAACGGGCTACGGATGAAAGTAAACTTCAAAAAGATGACAAAGAGCATCAGCAGCAGTTGAAAACTCCAGTACAAGGTCAGTCCCAACCGGTGGAAGCCACCAAATCGAAAAAGGCAGAGAAAGAGCAACAGCAAAAGTCTGACAAATCGGAGAAGGATAAGCAGCATCAAGCTGAAGAACCTGTCATCCCCACAAAGCGCAAGCGCGGCCGCAAAGAGCGCAAGTCCCCCACTCCCGTACCCATTCCGCTAgaagaaaaagaaataaaggAGGAGCCAGAGCCCCCCGAGCGACGCATGCGTAAGAGCCGCCACCAAGTGGACTATGTGGTGGAAGTCAAGGATGAAGAGGAAGAGGAGAAcgacgaggaggaggtggaCGATGACTCCTCGGCCACAATTTCGCCCCACAACAGCTCAACGGACGAGAGCTTCACTTCAATCAAACGTGAGTCATCCGAGGAGTCGCAGCGCAATGGAAGCGGTGCAATACACACCTGTAATTTCTGTGGCAAAACCTTCAAGCGTTTCTCGAGAATGCAAGACCACCTGCGTTTGCATACCGGAGAAAAACCATACGTATGTGGACAGTGTGGCAGGGCTTTCCGCTTGAAGATGCGTATGGTCGAGCACCAACTGCGTCATCGCGCCGAGAAGGCTTACAAATGCGAGATCTGTTCAATGCCACTGGCCACCAAGCAGGATTTATCGCTGCACATGCGTCACCACAAGAACGATCGCCGCTACAAGTGTGACAAGTGCAACAAGGGATTCGTACGCAGCTCAGATTTGTCCATCCACGTGCGGATTCACACCGGCGAAAAGCCCTACAGCTGTGATCTTTGCGGCAAGGCGTTCCGTGCTCGTCAAAATCTCGTGGTCCATCGACGCACTCATCTCGGCGATAAACCCATTCAGTGTGAGTTGTGCGACAAGCGCTTCGCCCGCAAGATCGACATGCGGGTGCACATGCGCAGGCACACAGGTGAAAAGCCGTACAACTGCGATGCCTGTCAGCGCGGATACTCCTCCCGAGTGAATCTGTTGCGGCACCAGGAGCGTGAGCATGGCAAAGAGGAGAAGGCCTCTGGAGCTGCAAAGGCGGGCAAAAAGAGCCCGGAGCCGACAAAGCAGCAAGAAAAAGAACCCAAAGCCAAAGCAGCACCACGACGTCCGCGACGCGAGAAGTTGCAACAGAAGATTGCAGCCCAGGAGAAACTTCTGCACGACCTGAAACGCAGCTTGAGTTCTCTGCCAGAAATTCCAGAGGAGTCATCACAAGCCAAACTCGATGTAGCTGGCCAGGAACTACCAGCGGATGCGGGAGCAGGGCGTGCCCAAGTGCAAGTCACAGTGTCCATGCAAATGGAACCGGCACGCAATCCCGACGACGATGAGGAGACCACGCCGGAGAAGGAGAATGCCTTGTCCAGCTCGACGACTGCCGATGGCAAGGCAAAGGCAAACCGCAAGATCACCAGCTACTTCACTGTGGTGGGTCAGCAGGCGGAAATCTAA
Protein Sequence: MSDMLKMANVANPNPLQTMKKTNGDDGESDESEMEEEEGEEDEEEEEDEDDLPDDVVLQIDSEDEAELEAQRIRLVEEEAAKTTKKAEKEQEQQQQEPQQAQVSNGKAEQLGETGKSKNKNKRGRPKRRASTSSQASSASIASLVSSGSLVAAEVLADEKSRRFIYSCSSCTHHYADSLILSRHFQQQHAEKPKRKRGKAKASLEETLVTPSLNLDLLEIGHLKPCAQLLVQGESLLQLCLACNSQFVDEVRFQEHLSQQHGYFKLLVPKEEPSDLPPQAMVTIPGALVKGNSQLQLPIPAPETPPPEQDAKETPPSTVSNDKEDLEMINAMVAEIAAERVKKTSSPKVSKMIIKLPTTNKRGRKRTKPEKIRDGKVKSEKSRERKQEKPEKKKKLDKKEEKLLDSEPSKPNDEAKQQKEKTENGLQQPVTIGIEQSQPDKVENDQPKPEESEKESHQLPKEAVADTQFPEKPEEQALEKPVSEGQSPEKDSMEQQSVTKENDKSLERSRTDQQSLEKVLKEQQSLEKFGKEKQLVDEAVKENQPLQKDSQEPEREEKDDTETHKLVIPNEDIQRATDESKLQKDDKEHQQQLKTPVQGQSQPVEATKSKKAEKEQQQKSDKSEKDKQHQAEEPVIPTKRKRGRKERKSPTPVPIPLEEKEIKEEPEPPERRMRKSRHQVDYVVEVKDEEEEENDEEEVDDDSSATISPHNSSTDESFTSIKRESSEESQRNGSGAIHTCNFCGKTFKRFSRMQDHLRLHTGEKPYVCGQCGRAFRLKMRMVEHQLRHRAEKAYKCEICSMPLATKQDLSLHMRHHKNDRRYKCDKCNKGFVRSSDLSIHVRIHTGEKPYSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDMRVHMRRHTGEKPYNCDACQRGYSSRVNLLRHQEREHGKEEKASGAAKAGKKSPEPTKQQEKEPKAKAAPRRPRREKLQQKIAAQEKLLHDLKRSLSSLPEIPEESSQAKLDVAGQELPADAGAGRAQVQVTVSMQMEPARNPDDDEETTPEKENALSSSTTADGKAKANRKITSYFTVVGQQAEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486769;
90% Identity: -
80% Identity: -