Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:4718560-4723288[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.7e-05 0.0016 18.5 2.6 1 23 93 115 93 115 0.97

2 11 9.1e-08 5.3e-06 26.3 1.7 1 23 121 144 121 144 0.97

3 11 2.3e-05 0.0013 18.8 0.6 1 23 150 172 150 172 0.97

4 11 1.7e-05 0.00099 19.2 0.5 1 23 178 200 178 201 0.95

5 11 1.5e-06 8.7e-05 22.5 0.9 1 23 208 230 208 230 0.97

6 11 0.011 0.61 10.4 0.7 1 23 236 259 236 260 0.95

7 11 0.0019 0.11 12.8 0.2 1 23 265 287 265 287 0.98

8 11 2.9e-06 0.00016 21.6 2.8 1 23 293 315 293 315 0.98

9 11 1.8e-05 0.0011 19.1 4.7 1 23 321 343 321 343 0.99

10 11 0.0017 0.1 12.9 0.9 1 23 349 374 349 374 0.95

11 11 0.0028 0.16 12.2 0.1 1 19 380 398 380 400 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.7e-05	0.0016	18.5	2.6	1	23	93	115	93	115	0.97
2	11	9.1e-08	5.3e-06	26.3	1.7	1	23	121	144	121	144	0.97
3	11	2.3e-05	0.0013	18.8	0.6	1	23	150	172	150	172	0.97
4	11	1.7e-05	0.00099	19.2	0.5	1	23	178	200	178	201	0.95
5	11	1.5e-06	8.7e-05	22.5	0.9	1	23	208	230	208	230	0.97
6	11	0.011	0.61	10.4	0.7	1	23	236	259	236	260	0.95
7	11	0.0019	0.11	12.8	0.2	1	23	265	287	265	287	0.98
8	11	2.9e-06	0.00016	21.6	2.8	1	23	293	315	293	315	0.98
9	11	1.8e-05	0.0011	19.1	4.7	1	23	321	343	321	343	0.99
10	11	0.0017	0.1	12.9	0.9	1	23	349	374	349	374	0.95
11	11	0.0028	0.16	12.2	0.1	1	19	380	398	380	400	0.95

Sequence Information

Coding Sequence: atggTACGCAGCCGACGCAGCGTGTCCAAGGAGGATGCCGTCTCCCTGCTTACGGACAGCGGAATCTCGTTGTCCTCGCCGCCGGCGGCGAGGGAATCTTCTCCAGGCCCCCCGCATTCAATAAAGAGGCGAAAGAGCAGCTTGGCTAGTCTGCGAGATGCCTGTGCGGAGGAGGAAGATGAAGACGGCGGCGAGCCGGACTCGAAGGATGCCGATTACGTGCAGCCCCTGCCGAAAAAGTCTGCTCGGAAGGCGGAGCCAATAAAAAGGAAGCACCATGTTTGCAGTCACTGCTCCAAAGAGTTCGGCGGCAAGACCGACTTGCAGCGACACATGCTCATCCACTCGGACGAAAGGCCGCACAAGTGCAAGGATTGTGGAAAGAGTTACCGCCAGGCTGTCAACCTCAAGAACCACATCACCACCGCCCACGAGCACCGGAAGCAGTTCGCCTGCTCGCAGTGTCCCAAGTCCTTCGCCCTTAAGGAGCGCCTGCGTCTCCACATGCGCCTCCACTCTGGCGAGAAGCCGTATCCATGCGCCCTCTGCGATAAGAAATTCGCCCGGGGAGGTCAGCTTCAGCAGCACATGGTTTCTCACCACAAGACGAGTATCCAGCAGTTCAACTGCACCAAGTGCTCGGCCAGTTTTTCAACTAACGCGAATCTGCGGGTGCACATGGAGCGCCACGAACAGGGTATGGAACACCGGTGCGGCATTTGTGAGAGCCAATTCGCCAACGAGCTGGCCCTACGGGCCCACATTAACCAGGAGCACCACAAGCTGACGCAATTCGAATGCGAGATCTGCCACAAGATGATTGAGCCGGACGAGGATCTGGCCACTCACATGCAGAAGCACGCCGCGGTTAAGACGCACGTGTGCGAGGTGTGCAACACGTATTTCACCCAGAAGAGCCAGTACAATGTACACATGAGGATGCATACGGGAGAACGGCCCTACCAGTGTAGGATTTGCCACCAGACCTTTGCCCACTCAAGCGTTCTAAAGCTGCACATCAGAAAGCACACGGGCGAAAAACCCTTTCGATGCCAGTTATGCGAGGACGACGTGGCCTTCTCTCAGCTGGCGCACCTAAAAAACCACATGAAGAAGATACACAAACAGCAGAAGCCATACATGTGCGAGGGGTGCCACGAGTTCTTCAAGATCAAGGTGGAGCTGCAGGCGCATGCGGAGCAGTGCGCCAAATGTCCTGCGGGTGGAGACGAGTCCGCTGGCAGTCAGTCTGAGGACGCACAAGTCCTCTCCACCATAAGATTCAACATGGCAGTGGTACTAAAGAAGATTAGCTCCGCGCAGAAGCTGCGCCAGTTGGGTTATGAAAAACGCCTGATCGATAATGTGATCATTGCCTCCCTAAAGCTGGCTCAACGACCCTCGCACGACGACGTCACGTTGACGCCTTTGGCCAGGCTTCGGATGAATGTGGAGGAGTTCCTCAAATGGATTGTGCCAGCACCTACAATGAAGAAATTCAGCGAAGAATTGCTGTCGATCGACACAATTCTTGACAAGATTGCCACCATGTACATGAAGCAGAAGTAG
Protein Sequence: MVRSRRSVSKEDAVSLLTDSGISLSSPPAARESSPGPPHSIKRRKSSLASLRDACAEEEDEDGGEPDSKDADYVQPLPKKSARKAEPIKRKHHVCSHCSKEFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAVNLKNHITTAHEHRKQFACSQCPKSFALKERLRLHMRLHSGEKPYPCALCDKKFARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTNANLRVHMERHEQGMEHRCGICESQFANELALRAHINQEHHKLTQFECEICHKMIEPDEDLATHMQKHAAVKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLCEDDVAFSQLAHLKNHMKKIHKQQKPYMCEGCHEFFKIKVELQAHAEQCAKCPAGGDESAGSQSEDAQVLSTIRFNMAVVLKKISSAQKLRQLGYEKRLIDNVIIASLKLAQRPSHDDVTLTPLARLRMNVEEFLKWIVPAPTMKKFSEELLSIDTILDKIATMYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612236;
90% Identity: iTF_00490210;
80% Identity: -