Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: ZNF296
Assembly: GCA_014743375.2
Location: NC:11188573-11193602[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00099 0.057 13.6 0.8 1 23 206 228 206 228 0.96

2 26 2.5 1.4e+02 2.9 3.3 1 20 234 253 234 256 0.80

3 26 0.0033 0.19 12.0 2.7 2 23 288 309 287 309 0.97

4 26 0.045 2.6 8.4 5.9 1 23 382 405 382 405 0.94

5 26 0.24 14 6.1 1.2 1 23 445 467 445 467 0.97

6 26 0.13 7.5 7.0 0.0 2 23 479 500 478 500 0.96

7 26 0.00083 0.048 13.9 0.1 1 23 575 598 575 598 0.98

8 26 0.011 0.65 10.3 1.3 2 21 608 627 607 628 0.93

9 26 0.031 1.8 8.9 5.2 1 23 637 659 637 660 0.95

10 26 0.0027 0.16 12.3 1.4 2 23 674 695 673 695 0.97

11 26 0.00026 0.015 15.5 7.1 1 23 703 725 703 725 0.97

12 26 1.9 1.1e+02 3.3 2.1 3 23 761 781 759 781 0.79

13 26 0.0024 0.14 12.4 0.4 1 23 863 886 863 886 0.94

14 26 0.0085 0.49 10.7 1.7 2 23 894 917 893 917 0.91

15 26 0.006 0.35 11.2 1.3 1 23 923 946 923 946 0.95

16 26 1.4e-05 0.00083 19.4 1.4 2 23 965 986 964 986 0.97

17 26 0.0002 0.011 15.8 1.0 1 23 993 1015 993 1015 0.98

18 26 0.049 2.8 8.3 0.0 2 21 1042 1061 1041 1062 0.93

19 26 0.0098 0.56 10.5 3.1 1 23 1112 1135 1112 1135 0.96

20 26 0.011 0.65 10.3 1.9 1 23 1172 1195 1172 1195 0.95

21 26 0.00062 0.035 14.3 2.7 1 23 1221 1244 1221 1244 0.98

22 26 5.4e-06 0.00031 20.7 0.2 2 23 1270 1291 1269 1291 0.95

23 26 0.00025 0.014 15.5 3.6 1 23 1297 1319 1297 1319 0.99

24 26 2.1e-06 0.00012 22.0 2.0 1 23 1325 1347 1325 1347 0.97

25 26 5.4e-08 3.1e-06 27.0 2.4 1 23 1353 1375 1353 1375 0.99

26 26 0.00053 0.03 14.5 0.2 1 22 1381 1402 1381 1405 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00099	0.057	13.6	0.8	1	23	206	228	206	228	0.96
2	26	2.5	1.4e+02	2.9	3.3	1	20	234	253	234	256	0.80
3	26	0.0033	0.19	12.0	2.7	2	23	288	309	287	309	0.97
4	26	0.045	2.6	8.4	5.9	1	23	382	405	382	405	0.94
5	26	0.24	14	6.1	1.2	1	23	445	467	445	467	0.97
6	26	0.13	7.5	7.0	0.0	2	23	479	500	478	500	0.96
7	26	0.00083	0.048	13.9	0.1	1	23	575	598	575	598	0.98
8	26	0.011	0.65	10.3	1.3	2	21	608	627	607	628	0.93
9	26	0.031	1.8	8.9	5.2	1	23	637	659	637	660	0.95
10	26	0.0027	0.16	12.3	1.4	2	23	674	695	673	695	0.97
11	26	0.00026	0.015	15.5	7.1	1	23	703	725	703	725	0.97
12	26	1.9	1.1e+02	3.3	2.1	3	23	761	781	759	781	0.79
13	26	0.0024	0.14	12.4	0.4	1	23	863	886	863	886	0.94
14	26	0.0085	0.49	10.7	1.7	2	23	894	917	893	917	0.91
15	26	0.006	0.35	11.2	1.3	1	23	923	946	923	946	0.95
16	26	1.4e-05	0.00083	19.4	1.4	2	23	965	986	964	986	0.97
17	26	0.0002	0.011	15.8	1.0	1	23	993	1015	993	1015	0.98
18	26	0.049	2.8	8.3	0.0	2	21	1042	1061	1041	1062	0.93
19	26	0.0098	0.56	10.5	3.1	1	23	1112	1135	1112	1135	0.96
20	26	0.011	0.65	10.3	1.9	1	23	1172	1195	1172	1195	0.95
21	26	0.00062	0.035	14.3	2.7	1	23	1221	1244	1221	1244	0.98
22	26	5.4e-06	0.00031	20.7	0.2	2	23	1270	1291	1269	1291	0.95
23	26	0.00025	0.014	15.5	3.6	1	23	1297	1319	1297	1319	0.99
24	26	2.1e-06	0.00012	22.0	2.0	1	23	1325	1347	1325	1347	0.97
25	26	5.4e-08	3.1e-06	27.0	2.4	1	23	1353	1375	1353	1375	0.99
26	26	0.00053	0.03	14.5	0.2	1	22	1381	1402	1381	1405	0.91

Sequence Information

Coding Sequence: ATGCTTCCCCCGGACATTTGTCGCACCTGTGCGCTGCAAAACGGCCAATTGCTGCCCTTGTCCACCTGCCTGGACAGAGACGCCTCCAAAAGTTACTATGATGTGCTCCAGGAACTCACGCAAATGGATACCCAGCTGGAGAGCTCGGATGATAATTTGCCGCAGCATCTGTGCACTGATTGCTGGACGAGATTGGAGAATGCCCACGCTTTCGTGGAGCAGGCCAAACGGGTCAATGGAGAGCTGCTGGCTCGTTTTAGGGAATGTCTGGATGAAATGCCCATCGACATTCCCGAGGAGCAGAACATAAAGACCGAGGTGAACCTCGATGAGGAGGGCAACAAGTGTGAGGTGGATGTGGACTCGGCGGCTATGGACATCAAATGGCAGCCGGAAAGTGCCAGCGAGGAGGACTTCCCTGACGCAGAGAGTGATGGAGATGAGGTGGACAAGAAGACCTATCATCTGCGTCGAAGTTCTCGAAAAGTCAAGCTGGCAGTGGAAAGCGAAGATGAGGATGTTAAACCATCTGAACCTGAAACGACGCCCGTCAAGCGGCGGCGTGGACGACCGCCCGGTCCAGGGAAGAGCCAATCCAAGACCGCCGATGGCCGCCACGCCTGTGAGGTCTGTGGGAAGACTTTCTCCTGGTATCGTGACATGCAGCGCCATGCCAGGATCCACTTCGAGCAGGCCTCGTTCGTGTGCGATACCTGTGGCAAGGGATTCCTGCGGAAGGACAAGTACATGTTCCACCTTCGCTGTCACAAGAAGCGCGAGGCCAAGTGGAAGGCTCTCCAATCAGGAAAAGAATGGCGATTTGCTGAGCGTCTATACAGTTCCGGCAGGTTAAAGAAAATCGAATGCAAATTGTGTGGATTGAGTTGCCATCGGATGGAAGAGCTTCGGCTTCACATCAAGACACATGTGGACGTGGAGAGCTTAGCCAATTTGAGAAAGGATAGCGATGTGGTTAGGGAGCATTTTCCCGGCTTTCCGTGCGACCTGGACGCTATCAAGCGGCATATCTGCGCTGATATAGCCGAAGGGCACTCAGAGAAGTTTGCCTGTATCGTGAATTTCCACGGTTATGAGTTGGGACTCAGTGATTCCGATGAAGAGTGTGAAAGCAAAGAGTCCAAATATCATTGCTTTGTGTGCAATCTGTTCTTCACTCGCAAACATCGCTTGATGAAACACACACTGGAGGAGCACTCTGAATCCGCTTCATCGCTTCCTTGGCAGCGCTGCAGTTCCTGCAAGGTTGGTTTCCTGTGCCTAACACTCTACAACGAACACTTGAGCACCCAATGCCACAGCAAATTAAAGCGCTATCGCTGCCGTAAATGTCCCGGAAAGTTTATGTGGCCGGAAAACCTGCAAAACCACGCGTGTTCCCATCGCCTCGAGGATAAGACTGTACCCAAGAAGATAATGTGCTCCTTGTGCGATGCTGCGCTACCCAGTTTGGCGCAACTTCGTGGTCACCTTATCACTCACCAACATGACTTAAATGGCATTAGTTCGGAATTCAATTCCTCCTTCTTTCTCTCGTTTTATCCTAATGGACTGGACTGCACTACCTCGGATCTGGCTGCTCGTATAGCTGAGGATTTCGAGGTCCAGGACTTTGATCGCTATTACAACATCTGCACTGAAAGTGGACAAGAGCTGGACCTTTTTGATTCCGAAACAGAGCAGAGCGAAGAGGAGACCAAGACATACACTTGTCTTCTATGCGGAGAGGTGGCGAGTACACTCACGGCTCTGATGCAGCACCAAAAGACTGCGCATGCCGATGGGATCAGTGATCTTCCCTGTCCCTGCGAGAATTGTGAAGCTCGGTTCGTCAGCAAAGCTCTTCTGCAACAGCATCGAAGGCACCGTTGCGCCAAGAAACACTCTCGTTTTCACTGCCAGAGTTGCAATATCCGATTCGTGTGGCAGTCCAACTATGAGAGACATCTAAAGACTCACCATAGCAAAAAGGAAGATGACGAACAAGGGGCCACCAAGTTGCAGTGTGACGAATGCGAAAAGGTATTCATCTGGCACAAAGATCTCAACCGTCACAAGCGACTGCATCAACCTCAATCCGCTGCTCAGTTTGACTGTCCACATTGTCACCGCAGGTTCCATCGCAAGGATGGCCTTAAATCTCACCTTAAAGTGCATGCGGGAGAACCAGTTCAAATAAAGGAGCATCGTTCCGTCCCCCACGTTGTCCAAGGCCTGGCGCTCTCCCGGCTTAGTCGTCCCCATGGTTGCAAGCAGATTCAGTGCATGATCTGCCTCTCACGTCACTCAAAGATCAGTGATCTGAGGACTCACATGAGGTCTCATCAATATGGATTACATTTTTCCGAAGATAGAGATATTCTTAGTGCCTCGAGAGCTTTTTACCCAGAACTGGAAACTGTCTTAGAAAGAAACGATCTTGCCGAACGGATTATGACTGATGTGCAAAAAGAATTCGAATTGGATAGATTTATTTCTATCACAAATGAGGCTGGCCTAGAACTAAATCTCGATAGCAGTGAAACTGATACTGAGTCTGAGCAAGAGGAGCTTCAAGCAGCACAAAACTATGCCTGTAATCTCTGCAACGCGGTTGTGAGAAGAAAGCATCAGTTGTATGCCCACCAGCTGGCGGAGCACAAGTGGGAGGACGCCTTTCTTGTATGCTCCCTTTGCCAAACTAGATTTGTTAACGAATCTTTGCTAGATCGTCATTCCAGAACCCTCTGTCACAATGCGcagaagatatttcagtgTCGCAAGTGCCCGCTTCGTTTCCGTTGGAAAGAGAACCTTAAGCTCCACATAAGCCTGTTCCATCAGCATGTCGAAATTCCAATCCCAGATGATGCTCCTCAAGTGGATGGTGGTCTGCAGTGCGAAAAGTGCCCGCGCAGCTTCAAGATGCAGAAGGATCTCACGCGTCATACATTAATGCACGGCCAGGAATCAACCATCTTCCGGTGCCGTTGGTGTGCACGTCGCTTCTATCGCAAGGCCAATCTCCTACAGCATATCGCGCGTCATGGGATAAGTGTAAGCCAGTTGCCTTATGCAGAGGCCATTCTGGATGCCTACGTGAATCCTGGAGGTCGGAAAAACGTGGAGTGTCGCGTATGCAGTGTGAGCTTTCCCACCATCTCGGCCCTGCGTTTGCATCTGGAAACCATGCCTGCAGGTAGCCACCACGACTTCTCCTCACCTCAGAACTACTCGATTACCAACCAGATGGGTTACGAGTTGGATTTGGATGACTCGGAGACTGATGATGATGGAGCTAGAACACATTTTAAACCACCTGGTGTTCCTGATTTTTACACATGCGGTATGTGCCAACTGAGGTGTTCGCGGAAATTCGAGCTCTATCAACACCAGCAGGCCATGCACCGGATGGAGAAGATCCCTGATGGCTGTGACAGGTGCATCTTCAAAAGCGTCTGCCCCGAAATAATTTCTCACCATAAAAAGACGCAGTGTGAGAACCGGGAAAAGCAGTTCACATGCACCCGATGTGGCTACAAGTTCATGTGGGAATCTAACCTATTGCATCATATGGAGTTGCAGCATGAAAAGTTAGATTATCAAGAGCTTGATGAATCTAAGGAGGCGTCTGGTGATGAACCAAAAGCCGAGAGCCAGGTATTCCAGTGTGGTCTTTGTACAAGGAAATACAATCGCAAGGATCGACTCACAGCGCACTTGAAGAAGTTCCATGGACCAGAAGGAAAGGATTCTAACAAAGTAAAGGTCTCGAATAGATCCACATCTCCTAAGGAACCAAAACGGTTCCTGTGTGCCTTTTGTGGCAAGGCGGTCAGCTCCTCCTCCAACCTGATCATCCATATGCGACGCCATACGGGGGAGAAGCCTTTTAAATGCGATTATTGCACAATGGCCTTTCCCCGATCCTCTGACCTCCAGTGCCATCGTCGGACGCACACCGGCGAACGTCCACATGTGTGCACCGTATGCCAGAAGGGATTTGCCCGCTCGTACAAACTGCAGCAGCACATGCGAATCCACAGCGGAGAGCGGCCCTACAAGTGCACCTACTGCGATAAGAGCTTCACGCAGTCCAACGACCTGACCCTCCACATCCGCCGGCACACAGGCGAGCGGCCTTACCAGTGCGGAATCTGCGGGGAGCGTTTTATCCAGGGAACCGCCCTGAAGAACCATCGCATGCAACAGAGCCACTTCGAGGAGGGACAGGAATCGGGGGAGCCTACGAGACGCACGGTTTTGGAGCAGTTTACTGTATAA
Protein Sequence: MLPPDICRTCALQNGQLLPLSTCLDRDASKSYYDVLQELTQMDTQLESSDDNLPQHLCTDCWTRLENAHAFVEQAKRVNGELLARFRECLDEMPIDIPEEQNIKTEVNLDEEGNKCEVDVDSAAMDIKWQPESASEEDFPDAESDGDEVDKKTYHLRRSSRKVKLAVESEDEDVKPSEPETTPVKRRRGRPPGPGKSQSKTADGRHACEVCGKTFSWYRDMQRHARIHFEQASFVCDTCGKGFLRKDKYMFHLRCHKKREAKWKALQSGKEWRFAERLYSSGRLKKIECKLCGLSCHRMEELRLHIKTHVDVESLANLRKDSDVVREHFPGFPCDLDAIKRHICADIAEGHSEKFACIVNFHGYELGLSDSDEECESKESKYHCFVCNLFFTRKHRLMKHTLEEHSESASSLPWQRCSSCKVGFLCLTLYNEHLSTQCHSKLKRYRCRKCPGKFMWPENLQNHACSHRLEDKTVPKKIMCSLCDAALPSLAQLRGHLITHQHDLNGISSEFNSSFFLSFYPNGLDCTTSDLAARIAEDFEVQDFDRYYNICTESGQELDLFDSETEQSEEETKTYTCLLCGEVASTLTALMQHQKTAHADGISDLPCPCENCEARFVSKALLQQHRRHRCAKKHSRFHCQSCNIRFVWQSNYERHLKTHHSKKEDDEQGATKLQCDECEKVFIWHKDLNRHKRLHQPQSAAQFDCPHCHRRFHRKDGLKSHLKVHAGEPVQIKEHRSVPHVVQGLALSRLSRPHGCKQIQCMICLSRHSKISDLRTHMRSHQYGLHFSEDRDILSASRAFYPELETVLERNDLAERIMTDVQKEFELDRFISITNEAGLELNLDSSETDTESEQEELQAAQNYACNLCNAVVRRKHQLYAHQLAEHKWEDAFLVCSLCQTRFVNESLLDRHSRTLCHNAQKIFQCRKCPLRFRWKENLKLHISLFHQHVEIPIPDDAPQVDGGLQCEKCPRSFKMQKDLTRHTLMHGQESTIFRCRWCARRFYRKANLLQHIARHGISVSQLPYAEAILDAYVNPGGRKNVECRVCSVSFPTISALRLHLETMPAGSHHDFSSPQNYSITNQMGYELDLDDSETDDDGARTHFKPPGVPDFYTCGMCQLRCSRKFELYQHQQAMHRMEKIPDGCDRCIFKSVCPEIISHHKKTQCENREKQFTCTRCGYKFMWESNLLHHMELQHEKLDYQELDESKEASGDEPKAESQVFQCGLCTRKYNRKDRLTAHLKKFHGPEGKDSNKVKVSNRSTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCTMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRMQQSHFEEGQESGEPTRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548203;
90% Identity: -
80% Identity: -