Dsup002475.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila subpulchrella
Gene Symbol
-
Assembly
GCA_014743375.2
Location
NC:12645943-12649630[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00011 0.0065 16.6 3.5 1 23 204 226 204 226 0.97
2 16 6.2e-06 0.00036 20.6 2.7 3 23 235 255 233 255 0.97
3 16 1.6e-08 9e-07 28.7 1.2 1 23 261 283 261 283 0.99
4 16 6e-05 0.0034 17.5 3.6 1 23 289 311 289 311 0.96
5 16 5.4e-07 3.1e-05 23.9 4.2 1 23 317 339 317 339 0.99
6 16 1.2e-05 0.00069 19.7 2.1 1 23 363 385 363 385 0.98
7 16 0.077 4.4 7.7 5.3 1 23 439 461 439 461 0.97
8 16 2.1e-06 0.00012 22.0 2.1 3 23 468 488 467 488 0.98
9 16 2.4e-07 1.4e-05 25.0 0.2 1 23 494 516 494 516 0.97
10 16 3.8e-07 2.2e-05 24.4 0.8 1 23 522 544 522 544 0.99
11 16 1.1e-05 0.00066 19.7 2.0 3 23 552 573 550 573 0.97
12 16 4.3e-06 0.00025 21.1 1.2 1 23 586 608 586 608 0.99
13 16 0.0011 0.064 13.5 0.6 1 23 614 637 614 637 0.96
14 16 4.1e-05 0.0024 18.0 1.6 1 23 651 673 651 673 0.96
15 16 4.4e-06 0.00025 21.0 1.4 2 23 680 701 679 701 0.97
16 16 1.8e-05 0.001 19.1 1.9 3 23 709 730 707 730 0.96

Sequence Information

Coding Sequence
ATGTTAATGGAGGACCAGTGCAAGGAAGTAAACAAACTATATGACCTGAGAAATATAATTTCCAAACGTCATTTCATTGCAACCCCATGTAAGAAAATGAAGGAAAAATGCAGGGTTTGCTTGCTGAAGCACCAGAACATGGTGCACATATTTAAGGGTCAAAATACACAGGATCTCGAAATATCCTTAGCAGATATGATTTCGGAATCAACCGGCTTTCCAGTTGCCAAAGGGGACCGTCTTCCGGAATTCATTTGTGTGCTTTGCCTGCAGGATATGACAAGCACATTCAGGGCCAGGGAAACCTGCGAGACCAACCAGCAGCTCGTCTGCCAAATCAAGGAGGAAATCATAGAGGAGGATTTTGTGGAGGATGAGGATTACAATGGACAGGACTGCGAGTCGTATTATGAAGAGGAAACCGATCACTTTGCGTGCCACGTGAAGAACGAACCCTTAGAAGAAGACTTTGCAGAGGAAGACATGGCCAATACTTTAGACAGCCCAATAGACCATTACAATGAAGAATGTAATGATGAAAACACCGAAGTGGAAGCTAGTAATAATATAAAGGATATTGATTATGACCCTACCAAAGAAGAACTTCCATTCAAATGTGATCGTTGTCCCAAGAGGTTTCGGAGCAAGTATTTTCTTAATCTCCACAGAAACGATCACAAGAAAAAACAGGCACCGCAGAACTGTGACCACTGCTCCAAATCCTTTCCTACTTCAGCACAAATGAGGAAGCACATGCTGACTCACACCGGTGTTAGGACATATAAATGTCCGCAGTGTCCCAAATCCTTTTTCAATAGTTCCAATCTTCAATCACACCTTCGTATTCATACTGGGGAGCGACCATTCAAGTGCTCTAAATGTCCTAAGTCGTTTATACAAAGAACCCATCTTGTTAATCACGACCGCACTCACACCGGAGAACGACCCTTCAAGTGTTCCGAATGCCACAAGACTTTTATACAACCTGCTAATCTTCATTCGCACATCAAAACTCACTGCAAGCAAATATCCAGACCTCGGAGAAGCACAAGAGCCAGGAGCCAAACTCTGACAGAGGAACCAATTTTCAATTGCTCCCATTGCCCTCAGTCCTTTGCCAACGAAGATGCTCTCCTTAATCACATGCACACTCACAACGCCTTGTTCGAGGAAGAAGTTTGCCAGATGTCCGACAACGAAACCGATCCATTCCAAGACATCGAAGTGGATATATTCGAGGACAATGATAAGGATGTTAAGCTAGAAAATCCGGAGGACGCAGCAGACAACAGCAATGATGACCAAGTTCCTGTGTTTAGATGTATTCATTGTCCAAAGGTGTGCTGGCGCAGTCATGATCTTAAGGCCCACTTAAGAAATCATTATGAGGAACCAAAAGCGTGTCCCCACTGCCCGAAAACTTTCAGTATCGTATCGACCTTTAAGAGACATATGCGGACTCACACGAAGGAAAAAAAGTTTGCGTGCGCCTATTGTCCAAAGGTCTTCAGAAATCCGGCGCAGCTTAAAGAGCACACTCGAACTCACACCGGAGAACGGCCTTATCAATGCCCGGATTGCCTGCAGTCATTTGCCTATAATTCCGTTCTGAAAAAACACATGCGTACTCACACTGGCGAAAGGCCGTTCTGGTGTAACGAATGCAACAAATCGTATGTGCAATTGGATCATCTTAAGCAGCACATGCTTAGGAACCACACAGAACAAATCTCCACTAAAAAAGATGACCCACAGTACAAGTGTAGCGATTGCTTGAAGACATATCAAAACCCAAGATCGCTTAGGAGACACATGTTGATTCACACCAGGAAAAAAGAATATAATTGCACCGATTGCTCAGAGTGCTTTATAGGAAAAGAAGCCTATACAAATCACGTATTGATTGAACACACCAAAAAAGAATTCGTCAGTAAGGCTCAGGAACACACGCATAATTGCCTACTCTGCCCAAAAACGTTTTCAAATGATGAAAATCTTAAAGTCCATACTCTCACACACTGTGTGAAAAAGCGCCTTACATGCTCACATTGTCCGGAAACGTTTGCGAACAAACAAACTCTTAGAATGCACATACGCATTCACACGGGGGAAAAGCCCTATGGCTGTACCAAGTGCAAAAGAACCTTTTCAAGAAGCGACTACCTTGTCAAGCACATCAGTAGACGCCATGAGAAGAAACCTTCGGAACCAGAACCACCCATATGCGAGATTACCATAGAGGAGGAGAATCTCAGTGCGCTCGAAGAACTTTAA
Protein Sequence
MLMEDQCKEVNKLYDLRNIISKRHFIATPCKKMKEKCRVCLLKHQNMVHIFKGQNTQDLEISLADMISESTGFPVAKGDRLPEFICVLCLQDMTSTFRARETCETNQQLVCQIKEEIIEEDFVEDEDYNGQDCESYYEEETDHFACHVKNEPLEEDFAEEDMANTLDSPIDHYNEECNDENTEVEASNNIKDIDYDPTKEELPFKCDRCPKRFRSKYFLNLHRNDHKKKQAPQNCDHCSKSFPTSAQMRKHMLTHTGVRTYKCPQCPKSFFNSSNLQSHLRIHTGERPFKCSKCPKSFIQRTHLVNHDRTHTGERPFKCSECHKTFIQPANLHSHIKTHCKQISRPRRSTRARSQTLTEEPIFNCSHCPQSFANEDALLNHMHTHNALFEEEVCQMSDNETDPFQDIEVDIFEDNDKDVKLENPEDAADNSNDDQVPVFRCIHCPKVCWRSHDLKAHLRNHYEEPKACPHCPKTFSIVSTFKRHMRTHTKEKKFACAYCPKVFRNPAQLKEHTRTHTGERPYQCPDCLQSFAYNSVLKKHMRTHTGERPFWCNECNKSYVQLDHLKQHMLRNHTEQISTKKDDPQYKCSDCLKTYQNPRSLRRHMLIHTRKKEYNCTDCSECFIGKEAYTNHVLIEHTKKEFVSKAQEHTHNCLLCPKTFSNDENLKVHTLTHCVKKRLTCSHCPETFANKQTLRMHIRIHTGEKPYGCTKCKRTFSRSDYLVKHISRRHEKKPSEPEPPICEITIEEENLSALEEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00486697;
90% Identity
iTF_00604978;
80% Identity
-