Dsup012823.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila subpulchrella
Gene Symbol
ftz-f1
Assembly
GCA_014743375.2
Location
NC:6391694-6442409[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 0.29 2.1e+03 -2.5 6.3 37 104 18 85 7 109 0.75
2 5 0.14 1e+03 -1.5 6.2 59 188 144 273 119 287 0.58
3 5 2 1.5e+04 -5.9 7.5 39 74 324 359 290 388 0.45
4 5 3.7e-19 2.7e-15 56.4 0.4 1 76 573 648 573 677 0.74
5 5 2.5e-70 1.8e-66 225.0 1.9 157 408 778 1022 762 1024 0.92

Sequence Information

Coding Sequence
atggaTACCTTCAATGTACCTTTGCTGGCGgagagcagcagcaacaactatGCAACAGAAGCTACGGGCAATCATCACCACctgcaacatcagcagcagcaacagcaacatcagcaacaacaactttTAATAGCACATCATCACAAGGATCAAATGTTGGCCGCTGGCAGTTCCCCAATGCTTCCCTTTTATTCCCACTTGCAGTTGCAACAGAAGGATGCCACTGCAACCATAGGgcctgcagcagcaacagttgcATCAGCTGCAACATCGGCGAGTGCCGACAACTTCAGTGCATTGCAAACGATCGATGCCAGTCAATTGGATGGCGGCATTTCCTTGAGCGGCTTGTGCGACCGTTTCTTTGTGGCCAGTCCAAATCCACACAGCAATAGCAATATGACACTCATgggcacagcagcaacaactaccactaacaataataataacaacaataccaacaacaataataataacaacaacaacaatgtggAGGCTAAGGCAGTGAGGCCATCGAACGGCAATTCGGTGATCATCGAATCTGTGACGATGCCATCGTTTGCCAATATTCTATTTCCCACCCACCGCAGCGCCAACGAGTGCATTGATCCCGCCCTGCTGCAAAAGAATCCCcaaaacaacagcaacagcagcggcaCTACTAGCATTATTGTGCCGCCCGTGGAATATCATCAATTGAAACCACTTGAAGTCAATTCCTCGACTTCCGTTTCCACCAGCAATTTCCTGTCCTCCACCACGGCTCAATTGTTGGACTTTGAGGTGCAGGTGGGCAAGGATGATAGTCACATCAGCACCACCACAGCGGGGCagggatcgggatcgggatcCGGTTCGGGATCGAGTGCCACTACAATAgtagcaacatcagcagcgcCAGTAGCAACGACAACATCCATTAACAACAACACTGCCAATCCAACCAGGAGCTCATTGCACAGCATCGAGGAGCTGGCCGCCAGCTCCTGTGCCCCGAAAACCACTTCGCCCAACAGCAACCACACTAGCAGCGCCAGTACCACACCGCAGCaacaccaccagcagcagcaacaccaccTGCAAAGCGGCAACCACAGTGGCTCCAATCTCAGCAGCGACGACGAGTCCATGTCCGAGGACGAGTTCGGCCTGGAAATCGACGACAATGGAGGCTACCAGGACACCACCTCCTCGCACTCGCAGCAGAGCGGAGGGGGCGGTGGGGCCGGCGGCGGCGGGGGCAACCTGCTCAACGGCAGCTCCGGCGGCAGCTCCGTCGGCGGTGGCTACATGCTGCTCCCCCAGGCGGCCAGTTCCAGTGgcggcaacaacaatggcAACCCGAATGGCGGCCACATGTCCTCCGGTTCGGTGGGCaacggcggcggcggcggcaacGGGGGCTCGGGCGGCGGCGGAGGCGGCCCGGGCAATCCCATGGGCGGCACGAGCGCCACGCCGGGTCACGGCGGCGAGGTGATCGACTTCAAGCACCTGTTCGAGGAGCTGTGCCCCGTGTGCGGCGACAAGGTGAGCGGCTACCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGCTCCTGCCACATCGACAAGACGCAGCGCAAGCGGTGTCCCTACTGCCGCTTCCAGAAGTGCCTCGAGGTCGGCATGAAGCTAGAGGCTGTTCGAGCGGATCGGATGCGGGGTGGACGAAACAAATTCGGTCCCATGTACAAACGGGATCGGGCGCGGAAGCTGCAGGTGATGCGGCAGCGGCAGTTGGCGCTGCAGGCACTGCGCAACTCGATGGGTCCGGACATAAAGCCAACGCCGATCTCGCCGGGCTACCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATTCAAATACCTCAGGTATCCTCACTCACCCAATCCCCGGATTCGTCGCCCAGCCCCATAGCCATTGCGCTGGGACAGGTGAATGCGAGCACGGGCGGTGTGATAGCCACGCCCATGAACGCCGGCAATGGCGGCAGCGGGGGCGGAGGTCTCAACGGGCCCAGTTCCGTGGGCAACGGCAATAGcagcaacggcagcagcggcggcaacAACACCAGCAGCACGGGCAACGGAGCGTCCGGCGGCGGAGGAGGGGGCAACAACGCGGGCGGCGGGGGAGGAGGCACCAATTCCGCCGACGGCCTGCATCGCAACGGCGGCAACGGCAACATCAGTTGCCACGAGGCTGGAATAGGATCTCTGCAAAACACGGCCGACTCGAAACTGTGcTTCGATTCTGGCACACATCCATCGAGCACGGCCGACGCGCTAATCGAGCCATTAAGAGTCTCACCCATGATTCGTGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAACTGTTTGCCCTGCTGCAGAAGCAAACCTACAACCAAGTGGAGGTGGATCTCTTCGAGCTGATGTGCAAGGTTCTCGACCAGAATTTGTTCTCGCAAGTGGACTGGGCACGGAACACCGTCTTCTTCAAGGATCTGAAGGTCGACGACCAAATGAAGCTGCTGCAGCATTCCTGGTCGGACATGCTGGTTCTGGATCACCTGCACCATCGAATCCACAACGGCCTGCCCGACGAGACGCAACTGAACAATGGCCAGGTCTTCAATCTGATGAGCCTGGGATTGTTGGGTGTGCCCCAGCTGGGCGACTACTTCAACGAGCTGCAGAACAAGCTGCAGGATCTGAAATTCGATATGGGCGACTATGTCTGCATGAAATTCCTAATCCTGTTGAATCCAAatGTACGGGGTATTGTCAACCGGAAGACCGTCTCCGAGGGACATGATAATGTGCAAGCTGCCTTGCTGGACTACACCCTCACCTGCTATCCGTCGGTCAATGACAAGTTCAGTAGGCTGGTAAACATTTTACCGGAAATCCATGCCATGGCCGCCCGCGGCGAGGAGCACCTGTACACCAAGCACTGCGCCGGCAGTGCGCCCACCCAGACGCTGCTCATGGAGATGCTGCACGCCAAGCGCAAGGTGTAG
Protein Sequence
MDTFNVPLLAESSSNNYATEATGNHHHLQHQQQQQQHQQQQLLIAHHHKDQMLAAGSSPMLPFYSHLQLQQKDATATIGPAAATVASAATSASADNFSALQTIDASQLDGGISLSGLCDRFFVASPNPHSNSNMTLMGTAATTTTNNNNNNNTNNNNNNNNNNVEAKAVRPSNGNSVIIESVTMPSFANILFPTHRSANECIDPALLQKNPQNNSNSSGTTSIIVPPVEYHQLKPLEVNSSTSVSTSNFLSSTTAQLLDFEVQVGKDDSHISTTTAGQGSGSGSGSGSSATTIVATSAAPVATTTSINNNTANPTRSSLHSIEELAASSCAPKTTSPNSNHTSSASTTPQQHHQQQQHHLQSGNHSGSNLSSDDESMSEDEFGLEIDDNGGYQDTTSSHSQQSGGGGGAGGGGGNLLNGSSGGSSVGGGYMLLPQAASSSGGNNNGNPNGGHMSSGSVGNGGGGGNGGSGGGGGGPGNPMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMNAGNGGSGGGGLNGPSSVGNGNSSNGSSGGNNTSSTGNGASGGGGGGNNAGGGGGGTNSADGLHRNGGNGNISCHEAGIGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPNVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFSRLVNILPEIHAMAARGEEHLYTKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00596709;
90% Identity
iTF_00505434;
80% Identity
iTF_00602648;