Basic Information

Gene Symbol
-
Assembly
GCA_037043435.1
Location
JBAMBK010001805.1:1-11634[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.0031 0.23 12.2 2.2 1 23 1030 1052 1030 1053 0.95
2 8 0.21 15 6.5 1.0 1 23 1058 1081 1058 1081 0.96
3 8 0.00018 0.013 16.1 1.0 1 23 1283 1306 1283 1306 0.96
4 8 0.0067 0.49 11.2 0.5 2 23 1315 1336 1314 1336 0.96
5 8 0.045 3.3 8.6 0.3 1 23 1343 1366 1343 1366 0.96
6 8 1.8e-05 0.0013 19.3 1.4 1 23 1372 1394 1372 1394 0.97
7 8 1.4e-05 0.0011 19.6 3.0 1 23 1399 1421 1399 1421 0.99
8 8 0.0032 0.23 12.2 6.2 1 23 1427 1449 1427 1449 0.99

Sequence Information

Coding Sequence
ATATCGTGTAACGATGGATTGCCCCAGGAGATTTGTCGGCAGTGCAAGGCGCAGTTCATAATGGTGGCCAAGTTCCGGCGGCGTTGTGTGCGCGTTCAGCAGCGACTTCACGACTTGGCCCAGGACATTGCCGAGCGGAAGGCGAGACGTCGCCCCGACAAGCgacaggagcaacagcagcaacaagagctGCCAAATGAGCCGGAAGACAGGGAGGAGGATTACATGCATCTGCCGGAATCACAATTGGAGCGCAAGCGTCGACTGACAATTCACCAGCTGGAACTGGAACCAAAAGAAGCCGCGACTGATGCGGAAGCGATTCCGCCATCGGCCAAATTGCGGCGCCTTCAGTCACGAGGTGCATCCCTGCCAGCCAACAAtattgagactgagactgaaacaacaacgacagagCAGAGCAAAGTTAACCAAAAGATTCACGAGCCTTGGAAAACGAAGGCGGCGCGAAAGCAGCTTTCCGAAACGTGGTCCGGCTGCTCGACGAGCTCCCCCTACACCACAGACAGCCGGAAAACGCCGGACGCGGTCGCACAGGTGGAGGCGGCGACACCAGCGAAGGATTCCGAAGTGACTACAGCATCAACCGCATTATCCACGTCTTCCTCCTCGGGTCAAACGTCGCCGGAGCATCTCAGCGATATATCCGTGAATGTATGTCGTGGCTTTGGCAACGACGAGACCTCCTCCTCCACAACATTGTCCTCCGTCGAAGGCCCAGCGACACCAACTCCAAATGCCAAACTCCGGTTTCCACGCAAGCACTCGGGGAGCAGTCCAAACAAATCCCACGTCGTGTTGCGTCGTGGACGACGGGCGAGGACAACGCTAAGTTATGGTCCGGTTAGGCGAACGAGACGCGTCATAAAAAAGACGCCGGAGAAGGAAAAGAAGTTGGCAACAGATGAGAATATTCCCGATGAAGCAGCGGAAAAGTTGAAAGAGGAAACGCCGTCCAGCAGCACCGATGAGACCTCGAAAACCACTTTGAACGGAAGCTTGTCCACGGCAACAGTCGAGGACAGCACACCAAGTGAaaagacagcaacaaaagacACGGAAACAGATATGGAAATgtgcaaaatgaaaaactcaacTCCCGCCAAGCTGAACAATGGATTGCAGGAGCAATCACAGTCGGTAGATCAGGAAGTAATCGCAGTGAGTGCAGATCAGTCGATGGAAACACCTGTGTCCACATTAAACGGACAGTTGCCAGTGGTGAATCCCGTTCAATTCGAGGAATTGACCTCATCCACGGAACTCAAAGGGCAAATGACACCAGGAGTGCCATCTCCAGACTGCGAAGTCGAAGTCACTTTGGCCAATGATGATCAGCAGAATTCCGAGTTGATTGTTAGCATACCACTTGACGCACTCGACGATGAACTGCAGCGTAAGCTCTGCAATGCTGGAGtggcagatgcagatgcagatggagGTGAAGGTGAATCAGAGCTGAAGGAGGAGGACGATGTGAATAACAATGCGAACGAAGAGCATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCGATACCAAACAAATTGAAGCAGAACCAGGTGGAGATGGAACCGGAACAGGAAAAGAGAAGCCaatggatgatgatgatatggCGTCACTGGAACAACTGGTGAAATTGCCCGAAACTGAGCAGCATAATGAATTGCAATTCTCACGTTCAACTGCCAACTCGATGGACTTTTTGGCCGAATTCGAGAAGCACTGCGAGAAGACGTTGAAACTGCAGACGGTGGAGGAGGCCAAGCAGCAGATGCAGGTGGAAATGAACGATGTGGAGAGCACACTGCATGGCATACTCAATGAGATGCAGGACCAGCATCTCTACACGCCCGTCTGTACGCCCATTGATGAATTCCTAACGCCCGCCGATTATGCGCCACTCAACGaaccggaaacggaaacggagtCGGCACCAGCAACGCCAGCGAGTGCCACAACAACGGCCAATCTCTATGAGCCGGAAGTGGTGCATcaacaccagcaacaccaacagcagcagcagcaggaacaacagcaacaacaggtgTTTGATAGCAGCAGCTTTAGCAATGAGTTGATTGGCTTTCAGAATGATATGCCCtgttttgagaatatcgaagCCTCGCCCGGATCGATGGCGGCACAGCAGAGTCTGCAATTGGAGCTGACGCAGTTGCTCAATGATTTGCAGCCAGCCacaagtggcagcagcaatcaacaacaacaacaacagctgttgcagttgcaatcgGAGACGGTCAGCTACGATGGACTGTATCCAACAGCGCCGGCAGCAACACCAGTTGCAGCCactggcaacggcaacagcagcaacaacaacagcagcaacaaggtGCAACTGATCCAAGTGCCGCCACAGGAGACACTGTGGCAGGCACAAGCAACGGCACAGCAGGCAACACAATTGCAATGGTCAACGGTGGGTGGACTGGAGTCCATCAAGACACTGCCCGTTGCCGACAACGACTCGGCGACACCAAcatcggcaacaacaacaacttactACATAAATGCCAGTGATATTTACCAGCAACCCAGCAGCAATATGTCTGGGGATACCTATGCTCTGCTGGACAACAATGAGAGTTACgtgctggagcagcagcaacaacagcaacagcaacatcaacagcagcagcaacaaccacaacaacagcccaTTATGATACTCATACAGCAACCAGAGATGCAACAACCGGTGGCATCTGCCAGCAATCCGCAACAGGCGCCGCTGCACATCACGTATGCTCCACAGCTGGCCAATGAGATGCATGCGTTccagtcacaacaacaacaacatcaacctCCGCCaccactacaacaacaactacaacagcgctcgcaacaacaacaacaacaaaatgtacaaaatcATACAGTATTAGGTTTAACAGCAGCTGTGGCCCCGCCCACCAGAGGCAGACCGCCCATGTTGAAGTGCCGCTTCTGCCAGAACGGACCGCGCTTCTCCAGCAGCTTGGAATACAGTCGTCACATCATTGAACTGCACCCGGCTGTGGCGCCCTTCAACTGTCCCCACTGCCCGCAGGCATTTGCCGGTCGCAGCAAGCGTAACCAGCACATCCTCAGCCACCATGTGGTGCAGCAATTCCATTGCGGCCAATGCTCACAAATGTTTCCCGCCCAGCGTGCTCTCGACCTGCATTTGCAGCGCTTTCACATGCCGCTCGCCGTTGCAGCGGATGCGGCAACGGAGGGTGTGCGTCTGGAGGAGGTGCAGCTCCAAATAGCAACCAAGGAGAAGCAACAACGACagtcacaacagcaacagcaacaatcacaGTCCGTGCAAGAGGCATCGTCACAGCTGACATCTGTTGAAGCGTCAAAAAGCGCGTTGCAGGCACGCAGGACGCGCATACTTTGTTGCCCGGACTGTGAGGACTGTAGTTCGTCTGCGACGGGACATCATCATCGCAGGGGACAGCAGCATTACGAGGAGCTGAGCAATTTGCAGTCACCGCCAACGGTTCTGACACCGCCCTCAACAATTGCTTCgctgccatcgccatcgccgcAGCCAACGCCGCACATCACGTTGCCATCGCCGGAGCAATCGGAGCCGGACTCGACCACAGCAACATTGCGGCAATTCCGTAAGCGCAGCACAGTGAGTGGCACTTCaacaccgacaacaacaacatcagcaacatcggCCACAATGCTgttgacagcagcagcatcgccGTCGCCCTCGTcatcgccgtcgtcgtcaACTATGGAGACGAGTGCGACGCTGCAAATGAGCAAACTCCGTGGTAGCCATCAATGTGTTCTCTGCGACAAGAGATTCACGAATATCATTGCCCTGCGCAAGCATCAACAGTTGGCCCACGATTCGCAGACCACGATGCCGTGGGTGTGTGCGATCTGTAAGCGTGGCTATAGGAAACGCACCGATATGGACAATCACATGAAATCGCACGAGCCAAAGGGCAGGCCATATGAGTGCAACGAGTGCTGGGTGCGATTCCCCGAATTTAAGCAGCTGGCGATGCACAAGTTCACCGTACACGAGCTGATCAAGCCGCATACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAATTTCATGGTGAGCGCGGTTTCCAGTGCGAAGAATGCGACGAGTCTTTCGCACATATCAAAGATTTTCGAAAACATCGACGCACCCACAACAGTGAATTGTTTTACAAATGCGAACATTGTCCACGCACGTTTCTACATTTTACGAGTTTTCGTGCTCATATGAACACCCATTTGCCGCTGGGTGTATTCCTCAATGATAAATCAACTGCACCGATGCCCATTAAAACGGAGAATCCCGCAACGCCCGGAACAAACGAGGAATTGCTGCCGTTGACGCCGCTTAGCAATTGCAATGTTAGCATCAATGAGGAGAGTCCCGGATCcgtggagatggagatggtgGGCAGCAGCGTGGCACAATCGCTGGAGATGCTTGTTGATACGCCATAA
Protein Sequence
ISCNDGLPQEICRQCKAQFIMVAKFRRRCVRVQQRLHDLAQDIAERKARRRPDKRQEQQQQQELPNEPEDREEDYMHLPESQLERKRRLTIHQLELEPKEAATDAEAIPPSAKLRRLQSRGASLPANNIETETETTTTEQSKVNQKIHEPWKTKAARKQLSETWSGCSTSSPYTTDSRKTPDAVAQVEAATPAKDSEVTTASTALSTSSSSGQTSPEHLSDISVNVCRGFGNDETSSSTTLSSVEGPATPTPNAKLRFPRKHSGSSPNKSHVVLRRGRRARTTLSYGPVRRTRRVIKKTPEKEKKLATDENIPDEAAEKLKEETPSSSTDETSKTTLNGSLSTATVEDSTPSEKTATKDTETDMEMCKMKNSTPAKLNNGLQEQSQSVDQEVIAVSADQSMETPVSTLNGQLPVVNPVQFEELTSSTELKGQMTPGVPSPDCEVEVTLANDDQQNSELIVSIPLDALDDELQRKLCNAGVADADADGGEGESELKEEDDVNNNANEEHFCQSATADSFNSAVALDTKQIEAEPGGDGTGTGKEKPMDDDDMASLEQLVKLPETEQHNELQFSRSTANSMDFLAEFEKHCEKTLKLQTVEEAKQQMQVEMNDVESTLHGILNEMQDQHLYTPVCTPIDEFLTPADYAPLNEPETETESAPATPASATTTANLYEPEVVHQHQQHQQQQQQEQQQQQVFDSSSFSNELIGFQNDMPCFENIEASPGSMAAQQSLQLELTQLLNDLQPATSGSSNQQQQQQLLQLQSETVSYDGLYPTAPAATPVAATGNGNSSNNNSSNKVQLIQVPPQETLWQAQATAQQATQLQWSTVGGLESIKTLPVADNDSATPTSATTTTYYINASDIYQQPSSNMSGDTYALLDNNESYVLEQQQQQQQQHQQQQQQPQQQPIMILIQQPEMQQPVASASNPQQAPLHITYAPQLANEMHAFQSQQQQHQPPPPLQQQLQQRSQQQQQQNVQNHTVLGLTAAVAPPTRGRPPMLKCRFCQNGPRFSSSLEYSRHIIELHPAVAPFNCPHCPQAFAGRSKRNQHILSHHVVQQFHCGQCSQMFPAQRALDLHLQRFHMPLAVAADAATEGVRLEEVQLQIATKEKQQRQSQQQQQQSQSVQEASSQLTSVEASKSALQARRTRILCCPDCEDCSSSATGHHHRRGQQHYEELSNLQSPPTVLTPPSTIASLPSPSPQPTPHITLPSPEQSEPDSTTATLRQFRKRSTVSGTSTPTTTTSATSATMLLTAAASPSPSSSPSSSTMETSATLQMSKLRGSHQCVLCDKRFTNIIALRKHQQLAHDSQTTMPWVCAICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFQCEECDESFAHIKDFRKHRRTHNSELFYKCEHCPRTFLHFTSFRAHMNTHLPLGVFLNDKSTAPMPIKTENPATPGTNEELLPLTPLSNCNVSINEESPGSVEMEMVGSSVAQSLEMLVDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00585524;
80% Identity
-