Dqui019539.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila quinaria
Gene Symbol
-
Assembly
GCA_035047525.1
Location
JAWNPO010000546.1:679358-687564[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.0031 0.25 12.2 2.2 1 23 1007 1029 1007 1030 0.95
2 8 0.2 16 6.5 1.0 1 23 1035 1058 1035 1058 0.96
3 8 0.00031 0.025 15.4 0.5 1 23 1275 1298 1275 1298 0.96
4 8 0.0066 0.53 11.2 0.5 2 23 1307 1328 1306 1328 0.96
5 8 0.044 3.5 8.6 0.3 1 23 1335 1358 1335 1358 0.96
6 8 1.7e-05 0.0014 19.3 1.4 1 23 1364 1386 1364 1386 0.97
7 8 1.4e-05 0.0011 19.6 3.0 1 23 1391 1413 1391 1413 0.99
8 8 0.0031 0.25 12.2 6.2 1 23 1419 1441 1419 1441 0.99

Sequence Information

Coding Sequence
ATGGTGGCCAAGTTCCGGCGGCGTTGTGTGCGCGTTCAGCAGCGACTTCACGACTTGGCCCAGGACATTGCCGAGCGGAAAGCGAGGCGTCGCCCCGACAAGCGGCAGGAGCAACAAGAGCTGCCAAATGAGCCAGAAGAAAAGGAGGAGGATTACATGCATCTGCCGGAATCACAATTGGAGCGCAAGCGTCGACTGACAATTCACCAGCTGGAACTGGAACCAAAAGGAGCACCGACTGATGCGGAAGCGATTCCGCCATCGGCCAAATTGCGCCGCCTTCAGTTGCGAGGTGCATCACTGCCAGCTAACAATATTGAgactgaaacaacaacaacaacaacgacagagCAGAACAAGGTTAACAAAAAGATACACGAGCCTTGGAAAACGAAGGCGGCGCGCAAGCAGCTTTCCGAAACGTGGTCCAGCTGCTCGACGAGCTCCCCCCACACCACAGACAGCCGGAACACGCCGGACGAGGTCACACAGGTGGAGGCGACGACTCCGCCGATGGATTCGGAAGTGACTAAAGCATCAACCGCCTTATCCACGTCTTCCTGCTCGGGTCAAACGTCGCCGGAGCATCTCAGCGATCTATCCGTGAACGTATGTCGTGGCTTTGGCAACGACGAGACTTCCTCCTCCACCACAGTGTCCTCCGTCGAGGCCCAAGCGACACCAGCTGCAAATGCCAAACTCCGGTTTCCACGCAAGCACTCGGCGAACAGTCCAAACAAATGCCACGTCGTGTTGCGTCGTGGACGACGGGCGAGGACAACGCTCAGTTATGGTCCGGTTAGGCGAACGAGACGCGTTTTAAAAAAGACGCAGGAGAAGGAAAAGAAGTTGGCAATAGATGAGGAAATTCCCGATGAAGCAGCGGAAAAGTTGAAAGAGGAAACGCCGTCCAGCAGCACCGATGAGACCTCGAAGACCACTTTGAACGGAGGTTTGTCAACGGCAACAATAAAGGACAGCACACCAAGTGGtaaaacagcaacaagtgACACGGAAATGGAATCGGAAATGTGCAAAATGGACAACTCAATTCCCGCCAAGCTGGACAATGGATTGCAGGAGCAATCACACTCTGTAGATCAGGAAATAAACGCAGCAGATCAGTCGATGGACACACCTGTGTCCACATTAAACGGACAGTTGCCAGTGGTGATCAATCCCGTTCAGTTCGAGGAATTGACCTCATCCACGGAACTCAAAGGGCAATTGACACCAGAAGTGCCATCTTCAGACTGCGAAGCCGAAGTCACTTTGGCCAATGGTGATCAGCAGAATTCCGAGTTAATTGTTAGCATACCACTTGACGCACTCGACGATGAACTGCAGCGTAAACTGTGCAATGCTGGAGCGGATGAGGTGGCGGATAGAGGTGAAGGTGAAGCTGAATCAGAGCTGAAGGAGGAGGACGATGTAAATAACAATGCGAACGAAGAGCATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCGAGACCAAACAAATTGAAGCAGAACCAGGTGGAGATGGAACCGCAACTGGAACAGGAAAAGACAAGTCaatggatgatgatgatatggCGTCACTGGAACAACTTGTGAAATTGCCCCAAACTGAGCGGCATAATGAATTGCAATTTTCACGTTCAACTGCCAACTCGATGGACTTTTTGGCCGAATTCGAGAAGCACTGCGAGAAGACTTTGAAACTGCAGGCGGTGGAGGAGGCCAAGCAGCAGATGCAGGTGGAAATGAACGATGTGGAGAGCACACTGCATGGCATACTCAATGAGATGCAGGACCAGCATCTCTACACGCCCGTCTGTACGCCCATTGATGAATTTTTAACGCCCGCCGATTATGCACCACTTAACGaaccggaaacggaaacggagTCGGCACCAGCAACGCCAGCGAGTGTCACAACAACGGCCAATCTCTATGAGCCAGAAGtggtgcagcagcaacaccaacagcagcaacaacaggtgtttgacagcagcagctttaGCAACGAGTTGATTGGCTTTCAAAATGATATGCCCTGTTTTGAGAATATCGAAGCCTCGCCCGGATCGATGGCGGCACAGCAGAGTCTGCAATTGGAGCTGACGCAGTTGCTCAATGATTTGCAGCCAGCCacaagtggcagcagcaacagcagcaatcaaCAACatctgttgcagttgcaatccGAGACAGTCAGCTACGATGGACTGTATCCAACAGCGCCGGCAGCAACACCAGTTGCAGCCACTGgcaacagaagcaacaacagcagcaacaaggtGCAACTGATCCAAGTGCCGTCACAGGAGACACTGTGGCAGGCACAAACAACGGCCCAACAGGCAACACAGTTGCAATGGTCAACGGTGGGTGGACTGGAGTCCATCAAGACCCTGCCCGTTGCGGGCATGGATAGCTTGAACAACGACTcggcgacaacagcaacaacaacagcagcagcagcaacaacaacaacttactACATAAATGCCAGTGATATTTATCAGCAACCCAGCAGCAATATGTCTGGGGATACATATGCTCTGCTGGACAACAATGAGAATTACGTgctggagcaacaacaacagcaacaacaacaacagcagcagcagcagcaaccacaacaacaacaacaacccatTATGATACTCATACAGCAACCAGAGATGCAACAACCGGTGGCATCTGCCAGCAACCCGCAACAGGCGCCGCTGCACATCTCATATGCTCCACAGCTGGCTAATGAGATGCATGCGTTccagtcacaacaacaacaacagcatccaccaccactacaacaactacaacagcgctcgcaacaacaacaacagcatgtACAAAATCACACAGTATTAGGTTTACCAGCAGCTGTGGCCCCGCCCACCAGAGGCAGACCGCCCATGTTGAAGTGCCGCTTCTGCCAGAACGGACCGCGCTTCTCCAGCAGCTTGGAGTACAGTCGTCACATCATTGAACTGCATCCGGCCGTGGCGCCCTTCAACTGTCCCCACTGCCCGCAGGCATTCGCCGGTCGCAGCAAACGTAACCAGCACATCCTCAGCCACCATGTGGTGCAGCAATTCCATTGCGGCCAATGCTCACAAATGTTTCCCGCCCAGCGTGCTCTCGACCTGCATTTGCAGCGCTTTCACATGCCACTCGCCGCCACAACGGATGCGGCAACGGAGGGTGTGCGTCTGGAGGAGGTGCAGCTCCAAATAGCCACCAAGGAGAAGCAGCAACGACAgtcacaacagcagcagcagcagcaacctcagcaacaacaagcacagtCAGTGAAAGAAGCATCGTCACAGCTGACAACTGTTGAAGCGTCAAAAAGCACGTTGCAGGCACGCAGGACGCGCATACTTTGTTGCCCGGACTGTGAGGATTGTAGTTCGTCGGCAACGGGACATCATCATCGCAGGGGACAACTGCAATACGAGGAGTTGGGCAATTTGCCGTCACCGCCAACGGTGCTGACACCGCCATCAACAATTGCCTCGctgccatcgccatcgccacaGCCAACGCCGCACATAACGTTGCCATCACCGGAGCAATCGGAGCCGGActcgacaacagcaacattgcGGCAATTCCGTAAGCGTAGCACAGTGAGTGGCACTTCaacaccgacaacaacaacatcagccaCATCAGCCACATCAGCAACGTCAGCAACATCGGCAACAATACTgatgacagcagcagcatcgccATCGCCCTCGTCATCGCCATCGTCGTCAACTATGGAGACGAGTGCGACGTTGCAAATGAGTAAACTCCGTGGTAGCCATCAGTGTGTTCTCTGCGACAAGGGATTCACGAATATCATTGCCCTGCGAAAGCATCAACAGTTGGCCCACGATTCGCAGACGACGATGCCGTGGGTGTGTGCGATCTGTAAGCGTGGCTATAGGAAACGCACCGATATGGACAATCACATGAAATCGCACGAGCCAAAGGGCAGGCCGTATGAGTGCAATGAGTGCTGGGTGCGATTTCCAGAATTTAAGCAGCTGGCGATGCACAAGTTCACCGTACACGAGCTGATCAAGCCGCATACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAATTTCATGGTGAGCGCGGCTTCCAGTGCGAAGAATGCGACGAGTCTTTCGCACATATCAAAGATTTTCGAAAACATCGACGCACCCATAACAGCGAATTGTTTTACAAGTGCGAACATTGTCCACGAACGTTTCTACATTTTACGAGTTTTCGTGCTCATATGAACACCCATTTGCCGCTGGGTGTATTCCTAAATGATAAATCAACTGCACCGATGCCCATTAAAACGGAGAATCCCGCAACGCCCGGAACAAACGAGGAATTGCTGCCGTTGACGCCGCTTAGCAATTGCAATGTTAGCATCAATGAGGAGAGTCCCGGATCCGTCGAGATGGAGATGGTGGGAAGCAGCGTGGCACAATCGCTGGAGATGATTATTGATACGCCATAA
Protein Sequence
MVAKFRRRCVRVQQRLHDLAQDIAERKARRRPDKRQEQQELPNEPEEKEEDYMHLPESQLERKRRLTIHQLELEPKGAPTDAEAIPPSAKLRRLQLRGASLPANNIETETTTTTTTEQNKVNKKIHEPWKTKAARKQLSETWSSCSTSSPHTTDSRNTPDEVTQVEATTPPMDSEVTKASTALSTSSCSGQTSPEHLSDLSVNVCRGFGNDETSSSTTVSSVEAQATPAANAKLRFPRKHSANSPNKCHVVLRRGRRARTTLSYGPVRRTRRVLKKTQEKEKKLAIDEEIPDEAAEKLKEETPSSSTDETSKTTLNGGLSTATIKDSTPSGKTATSDTEMESEMCKMDNSIPAKLDNGLQEQSHSVDQEINAADQSMDTPVSTLNGQLPVVINPVQFEELTSSTELKGQLTPEVPSSDCEAEVTLANGDQQNSELIVSIPLDALDDELQRKLCNAGADEVADRGEGEAESELKEEDDVNNNANEEHFCQSATADSFNSAVALETKQIEAEPGGDGTATGTGKDKSMDDDDMASLEQLVKLPQTERHNELQFSRSTANSMDFLAEFEKHCEKTLKLQAVEEAKQQMQVEMNDVESTLHGILNEMQDQHLYTPVCTPIDEFLTPADYAPLNEPETETESAPATPASVTTTANLYEPEVVQQQHQQQQQQVFDSSSFSNELIGFQNDMPCFENIEASPGSMAAQQSLQLELTQLLNDLQPATSGSSNSSNQQHLLQLQSETVSYDGLYPTAPAATPVAATGNRSNNSSNKVQLIQVPSQETLWQAQTTAQQATQLQWSTVGGLESIKTLPVAGMDSLNNDSATTATTTAAAATTTTYYINASDIYQQPSSNMSGDTYALLDNNENYVLEQQQQQQQQQQQQQQPQQQQQPIMILIQQPEMQQPVASASNPQQAPLHISYAPQLANEMHAFQSQQQQQHPPPLQQLQQRSQQQQQHVQNHTVLGLPAAVAPPTRGRPPMLKCRFCQNGPRFSSSLEYSRHIIELHPAVAPFNCPHCPQAFAGRSKRNQHILSHHVVQQFHCGQCSQMFPAQRALDLHLQRFHMPLAATTDAATEGVRLEEVQLQIATKEKQQRQSQQQQQQQPQQQQAQSVKEASSQLTTVEASKSTLQARRTRILCCPDCEDCSSSATGHHHRRGQLQYEELGNLPSPPTVLTPPSTIASLPSPSPQPTPHITLPSPEQSEPDSTTATLRQFRKRSTVSGTSTPTTTTSATSATSATSATSATILMTAAASPSPSSSPSSSTMETSATLQMSKLRGSHQCVLCDKGFTNIIALRKHQQLAHDSQTTMPWVCAICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFQCEECDESFAHIKDFRKHRRTHNSELFYKCEHCPRTFLHFTSFRAHMNTHLPLGVFLNDKSTAPMPIKTENPATPGTNEELLPLTPLSNCNVSINEESPGSVEMEMVGSSVAQSLEMIIDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00602142;
90% Identity
iTF_00602142;
80% Identity
-