Basic Information

Insect: Drosophila sturtevanti
Gene Symbol: L_1
Assembly: GCA_018150375.1
Location: JAECWJ010000564.1:671707-678472[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.2e-06 0.00065 19.9 2.9 1 23 185 207 185 207 0.98

2 14 0.32 22 5.7 6.2 1 23 213 235 213 235 0.97

3 14 1.5e-07 1.1e-05 25.5 3.2 1 23 241 263 241 263 0.99

4 14 1.1e-05 0.00079 19.7 0.4 1 23 269 291 269 291 0.99

5 14 0.025 1.7 9.1 0.7 1 23 455 477 455 477 0.97

6 14 0.076 5.4 7.6 0.1 3 23 486 506 485 506 0.93

7 14 2.9e-05 0.002 18.4 0.3 1 23 514 537 514 537 0.93

8 14 0.0023 0.16 12.4 1.1 1 23 646 669 646 669 0.97

9 14 0.0045 0.32 11.5 1.2 2 23 830 852 829 852 0.96

10 14 0.1 7.3 7.2 0.1 1 23 858 880 858 880 0.92

11 14 2.1 1.5e+02 3.1 1.7 2 23 888 909 887 909 0.95

12 14 0.67 47 4.6 0.5 2 23 1021 1042 1021 1042 0.94

13 14 0.0057 0.4 11.2 0.0 1 23 1052 1075 1052 1075 0.96

14 14 0.00021 0.015 15.7 1.2 1 23 1082 1104 1082 1104 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.2e-06	0.00065	19.9	2.9	1	23	185	207	185	207	0.98
2	14	0.32	22	5.7	6.2	1	23	213	235	213	235	0.97
3	14	1.5e-07	1.1e-05	25.5	3.2	1	23	241	263	241	263	0.99
4	14	1.1e-05	0.00079	19.7	0.4	1	23	269	291	269	291	0.99
5	14	0.025	1.7	9.1	0.7	1	23	455	477	455	477	0.97
6	14	0.076	5.4	7.6	0.1	3	23	486	506	485	506	0.93
7	14	2.9e-05	0.002	18.4	0.3	1	23	514	537	514	537	0.93
8	14	0.0023	0.16	12.4	1.1	1	23	646	669	646	669	0.97
9	14	0.0045	0.32	11.5	1.2	2	23	830	852	829	852	0.96
10	14	0.1	7.3	7.2	0.1	1	23	858	880	858	880	0.92
11	14	2.1	1.5e+02	3.1	1.7	2	23	888	909	887	909	0.95
12	14	0.67	47	4.6	0.5	2	23	1021	1042	1021	1042	0.94
13	14	0.0057	0.4	11.2	0.0	1	23	1052	1075	1052	1075	0.96
14	14	0.00021	0.015	15.7	1.2	1	23	1082	1104	1082	1104	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAAATGTTATATCGTGGTCCTAGTTCCCGATTGGAGAATTTAATTGAAAAAATTCAGGCCACCAAGGAGATAACAAATAACGATATGTACAGCACTCACACCTCATCGAGCTACTCGCCCAGTATTTCGGATGGAACCCTGACACCCAATTCCCATCATCATTTGCCTGCCTCAGTTCCAAGTGGCTTGCCAGATGATCATCAAAACGAAATAAAGGCTCATGGCGAAGGAAAGGATCTACAGCAACTACAACATTCGCAGAGCTTTAAACCGAAGCGTCCTTCACATTTCCATCATCATCATCATCATCATTACCATCATCAGCAGGCTTTGAAAATTGCCAACAAGTTACGCAAAATCAATAAAGAGAGTAACAAAATGGGTTCTGGCACGGGCACGGGCACGGGCACTGGAACGGGTACTGGCACAGCCACTGGAGCGGAAGATGGAGGCATTGGCACTGGAGCCGCCTCCGCCGATGGTACCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGCCGAGGCGACGGTTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAACATCACGTGCAGAGCCATGCCGAACATCTGCCCTTTAAGTGCGAATACTGTGCCAAGCTATTCAAGCATAAACGTTCCCGAGATCGTCACAAGAAACTTCATACAAATGAACGAAACTACAAGTGTCCGCATTGTGAGGCAGCATTTTCAAGAAGCGATCATTTAAAGATTCATATGAAAACTCACGACATACAGAAGCCGTTCCAGTGCAGTATGTGCAATCGTGGCTATAATACAGCGGCGGCCTTAACCTCACACATGCAGAAGCATAAGAAGAATGCAGCCATTTTGGCTGCTGGCGGTAATCCGAATGCACTTAACTATAGTCCGCGATCGACAGGTTCCGCTTCGGTATCATCGAGTAATAGCAGCTTGCACAAGCGTCGCTATGCCTTGGCGTTGGCCAATAACGATAGCAGTAGTCGAAGTCGTAGTCCCAGTCGTTTGGATTATCCGAAACGTTCCAGAATCAATGCAAATCACTCAACACCCACTCCAATGCTGAGCATTGCTGGACTTTTCCAGCATATGCGATCCACTCATTTGGATCGCCTTAGTTCACCACCAGCGACAATCGCTAGCTACTACGAGCACTTCAATCGTCTGGAAGCGCCGAAGCAAATCAAACAGGACTTGTCTAGTCCACAGCGAAAAGTAGAAGAGCCAGAAGAGTTACCAACGGATTTAAGTAGCAACAAGAGACAGATCGATGAACCCACAGCAACTCCATCCTCTGGACCAGTACCAGCACCGGGAGTCTTCTTTTGCAATCAGTGTAATGCCGGTCTACCGGACTTTGAGAGTTTTCGGAATCATCTTAAGACTCACATTGCCGAGGGCATGCAACTCCTTTGTCCACATTGTGGTCTCACTTTACCCGAACAGCAGGAGTATGAGCGTCATGTGGTAGCCCATTTCTTGATCACCAACTCGGAATTTAATTGTAGTAGCTGCGGCAAAACTTTCGCCAAATCTGAAGATCTCCAACAACATTTGCTAGCCGAGCACGTCGTAACCATGATGAAGTGCGCCTTGTGTTCGGAACTGTGCGATAATCGCATGGCCATGCAGTTGCATTTAGCCTGTACCCATAGTCAAGAAACCAAGCTTCTGAGATGCAGTGCTTGCATGGAGCTCTTCCGTTCCGATGCTGAGTTTCATGTGCATGTAAAGACACGTCATCAACTGGCCTTAGGCAATCAGAGTGGTGGAGTTGTGGGATCAGTCGCAAGCGGAGTTAGTCCAGCCAATCCTCTACAGTGTATGTTTTGTCGTGCAGTTTGCTCTTCGGAACTGGAGATGCATTTTCACTTGGCCGCACATGCCCGACAATTTCGTTGTCCATCCTGTCCGGAGACATTCCACGTGGAGTTCTTGCTTGATAGGCATATGCAAAGCCAACATGGTGGCATAAAGGAGACCAAGGAGCAAACATCCCCCAATATGGGTAGTTTGTATGTGAATGCTTTGCTACCCCCTCTGGCGGCAGCCGCTGCCGCTGCAGCAGTTACCAACAACAACAACAGCATCATTGACTATAATGTGGCATTCAAATTCAAGGGTCTGTTTGGTGGAGGAGGTCCTCCATCGGCTGCAGCAGCCAAGTTCTACAGTCCATTGCAAGTGGATACGAAAGCACAACAGGCCTCCCCCCATCCAGCCTTAATGTATGGCCTAAGTCAGCGATATCTTATGGAAATGTATAAGGCCAAGTCAATTTCACCGGCTCCGCCACCAACCACAGAGCCACCTCCAGGAACGGCCACAACCCAACCACCCACCACCTTCAGTTGTGGCATGTGCGAGCGTCAGGATCTACGCAGCGAAGCAGAACTTCATTCTCATCGTAAGTTAGCCCACAATCTTAAGACCGGTGTCAGTCTACGATGTGCATATTGTGCTGGCAATTTCAAGTCCAGGGCCGAGCTGGAACAGCACATGAAGAGCTGTCATAATTCGACGGGTAAACACAAATGTCTAATTTGTGATGAAATCTTTCCATCTCCTGCCATCCTGGCTGAGCATAAGTTGCAGCATTCTAAAGTAGGACAATCGGGCAAATGTTCTCACTGTTCCCATCAACTGGAGGATGTGGCCGCCTTTCGCAATCATCTCAGTGAACATGGTAGTGATGGAAGTTTGCCACTGGCCTGCATTTGCTGCCGCCAGACTCTGCATTCTGAATTCGAACTGTGTTTGCATGCCAAATTTCATACAAAATCATCGGTGGGCACTTCGAGAGGCAGTCTTCAGGAGCCAGTGTGTGCCTTGTGTCTAGAGCCACTTCCGGCCGTGGGACCCACAATTGACGGGCCCACTCCAGCCAAACTCTGTGAGAAATGCTTGCGAAAACACAATTTGAATGGCAAGAGAAACAAGCTAACAGATACCCCTTCCGTCAATGTGGCGTCTGGAACTGCAACTGTTGCTCCTAGCCACCCACCCTTTCTGGAAAATCGTTGTAATCTGTGCAAAATGATTTTACCCCATGCCCAAAAACTTCAAGAACATTTGGTTGAACACACTTTCGCTGGAACCGAACAACGTGGCTTCAATTGCTATATCTGTTCAGCCGTCTTCACTGCCCCCGCTGGCCTACTTAATCATATGTCTGTGGAGCATGGTGCCCAATCGCGACCCTATGATTGCAATTTGTGTCCTGAGAAGTTCTATTTTCGAGCTGAGCTCGAACACCATCAGCGTGGACACGAATTGCGTCCATTAACAGCGACGCGCCCTTCTTTAACTAAACAGGAGCCGCACTGTACACCAATTAGTCCGACTCTTAGTCCCACAGCTGTTAAACAGGAGATCTATGAATCAGAAACTCAGGCCTCTCTTGGTCAAGATGTTGATGATAATGGCGAGGATGCATCGACAAATGATGCCCAGGAGGAAGAGGAGTATATTGAAGTAGAACAAATGCCTCACGAAACGAGATCGGAAGATTTAATGGAACGATCAAGCAACAGCTCATAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSHHHLPASVPSGLPDDHQNEIKAHGEGKDLQQLQHSQSFKPKRPSHFHHHHHHHYHHQQALKIANKLRKINKESNKMGSGTGTGTGTGTGTGTATGAEDGGIGTGAASADGTTKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASVSSSNSSLHKRRYALALANNDSSSRSRSPSRLDYPKRSRINANHSTPTPMLSIAGLFQHMRSTHLDRLSSPPATIASYYEHFNRLEAPKQIKQDLSSPQRKVEEPEELPTDLSSNKRQIDEPTATPSSGPVPAPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLLCPHCGLTLPEQQEYERHVVAHFLITNSEFNCSSCGKTFAKSEDLQQHLLAEHVVTMMKCALCSELCDNRMAMQLHLACTHSQETKLLRCSACMELFRSDAEFHVHVKTRHQLALGNQSGGVVGSVASGVSPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKETKEQTSPNMGSLYVNALLPPLAAAAAAAAVTNNNNSIIDYNVAFKFKGLFGGGGPPSAAAAKFYSPLQVDTKAQQASPHPALMYGLSQRYLMEMYKAKSISPAPPPTTEPPPGTATTQPPTTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSHQLEDVAAFRNHLSEHGSDGSLPLACICCRQTLHSEFELCLHAKFHTKSSVGTSRGSLQEPVCALCLEPLPAVGPTIDGPTPAKLCEKCLRKHNLNGKRNKLTDTPSVNVASGTATVAPSHPPFLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLNHMSVEHGAQSRPYDCNLCPEKFYFRAELEHHQRGHELRPLTATRPSLTKQEPHCTPISPTLSPTAVKQEIYESETQASLGQDVDDNGEDASTNDAQEEEEYIEVEQMPHETRSEDLMERSSNSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00618656;
90% Identity: iTF_00604367; iTF_00555336;
80% Identity: -