Basic Information

Insect: Drosophila nebulosa
Gene Symbol: L
Assembly: GCA_018150735.1
Location: JAECWO010000031.1:24074674-24081113[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 1e-05 0.00073 19.9 2.9 1 23 178 200 178 200 0.98

2 16 0.35 25 5.6 6.2 1 23 206 228 206 228 0.97

3 16 1.7e-07 1.2e-05 25.5 3.2 1 23 234 256 234 256 0.99

4 16 1.2e-05 0.00089 19.6 0.4 1 23 262 284 262 284 0.99

5 16 2.5 1.8e+02 2.9 0.1 2 13 363 374 362 379 0.80

6 16 0.0027 0.2 12.2 0.4 2 23 416 438 415 438 0.96

7 16 0.027 2 9.1 0.7 1 23 511 533 511 533 0.97

8 16 0.043 3.1 8.4 0.1 2 23 541 562 540 562 0.91

9 16 4.3e-05 0.0031 17.9 0.1 1 23 570 593 570 593 0.93

10 16 0.0025 0.18 12.3 1.1 1 23 702 725 702 725 0.97

11 16 0.0049 0.36 11.4 1.2 2 23 888 910 887 910 0.96

12 16 0.11 8.2 7.1 0.1 1 23 916 938 916 938 0.92

13 16 6.5 4.7e+02 1.6 1.1 2 23 946 967 946 967 0.94

14 16 0.73 53 4.6 0.5 2 23 1080 1101 1080 1101 0.94

15 16 0.0059 0.42 11.2 0.0 1 23 1111 1134 1111 1134 0.96

16 16 0.00023 0.017 15.6 1.2 1 23 1141 1163 1141 1163 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	1e-05	0.00073	19.9	2.9	1	23	178	200	178	200	0.98
2	16	0.35	25	5.6	6.2	1	23	206	228	206	228	0.97
3	16	1.7e-07	1.2e-05	25.5	3.2	1	23	234	256	234	256	0.99
4	16	1.2e-05	0.00089	19.6	0.4	1	23	262	284	262	284	0.99
5	16	2.5	1.8e+02	2.9	0.1	2	13	363	374	362	379	0.80
6	16	0.0027	0.2	12.2	0.4	2	23	416	438	415	438	0.96
7	16	0.027	2	9.1	0.7	1	23	511	533	511	533	0.97
8	16	0.043	3.1	8.4	0.1	2	23	541	562	540	562	0.91
9	16	4.3e-05	0.0031	17.9	0.1	1	23	570	593	570	593	0.93
10	16	0.0025	0.18	12.3	1.1	1	23	702	725	702	725	0.97
11	16	0.0049	0.36	11.4	1.2	2	23	888	910	887	910	0.96
12	16	0.11	8.2	7.1	0.1	1	23	916	938	916	938	0.92
13	16	6.5	4.7e+02	1.6	1.1	2	23	946	967	946	967	0.94
14	16	0.73	53	4.6	0.5	2	23	1080	1101	1080	1101	0.94
15	16	0.0059	0.42	11.2	0.0	1	23	1111	1134	1111	1134	0.96
16	16	0.00023	0.017	15.6	1.2	1	23	1141	1163	1141	1163	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAAATGTTATATCGTGGACCCAGTTCCCGTTTGGAGAATTTAATCGAAAAGATTCAGGCCACCAAGGAGATAACCAATAACGATATGTACAGCACTCACACCTCATCGAGCTACTCGCCCAGCATCTCGGATGGAACCCTGACACCCAATTCCCATCATCATTTGCCTGCCTCGGCCGCAACTGGCTTGCCGGAGGATCACCAAACAGAACTAAAGGCTCATGGCGACCGAGACCCCAAGGATCCCTCGCAGCTATTCAAGCCGAAGCGTCCCTCACACTTCCATCACCATCATCACCATCACTATCACCATCAGCAGGCTCTGAAAATTGCCAACAAGTTACGCAAAATCAATAAAGAGACAAACAAAATGGGCTCAGGCACTGGCACGGGCACGGGCCCCGGCTCCGGCACCGCTGCTGAAGATGGAGGAACTGGCATCGGAGGTGCCTCCTCCGATGCTGCGACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGCCGAGGCGACGGTTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTGCAGAGCCACGCCGAACATCTGCCCTTCAAGTGCGAGTACTGTGCCAAGCTGTTCAAGCACAAGCGTTCCAGAGATCGTCATAAGAAACTACATACAAATGAGCGAAACTACAAGTGTCCACATTGTGAGGCGGCATTCTCGAGAAGTGACCATTTGAAGATCCATATGAAAACCCATGACATACAGAAGCCATTCCAGTGCAGCATGTGCAATCGTGGCTATAATACGGCAGCCGCTTTGACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCCATTTTGGCTGCTGGCGGCAATCCTAATGCCCTCAACTATAGTCCGAGATCGACGGGTTCCGCTTCGGTGTCATCGAGTAACAGCAGTCTGCACAAACGTCGCTATGCCTTGGCTTTGGCCAACAATGACAGCAGCAGTCGCAGTCGCAGCCCAAGTCGTTTGGACTATCCGAAACGGTCAAGGATCAATACAAACCACTCCACACCCACTCCCCTGCTAAGGTGCAGCTATTGCCCCAAGGTGACGGAGTTCAGTAGTCTGGAACAATTGAATGCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGTCCTTCGAACTGAACTGTGAGTACTGCACCATGAAATTTGGCAGCATTGCGGGACTTTTCCAGCACATGCGGTCCACGCATTTGGATCGCCTCAGTTCCCCACCATCGACCATCGCCAGCTACTACGAGCACTTCAATCGCCTGGAAATGCCCAAGCAAATCAAACAGGATCTGTCCAGTCCACAGCGGAAAGCAGAGGAGCCAGAGGAGCTACCCACAGATTTGAGTAGCAACAAGAGACAGATGGAGGAGCCAACACCGGCTCCAGCAGCTGGACCTGTCGCTGCTCCGGGAGTCTTCTTTTGCAATCAGTGCAACGCCGGACTGCCGGACTTTGAGAGCTTCCGCAATCACCTAAAGACCCACATAGCCGAGGGGATGCAGTTGATATGTCCACATTGTGGCCTCACTTTGCCCGAACAGCAGGAGTATGAGCGTCACGTGGTGGCCCATTTCTTGATCACCAACTCTGAGTTCAATTGCAGTAGCTGCGGCAAGAGCTTCGCCAAAGCCGAGGATCTGCAGCAACATTTGCTGGCGGAGCACGTCGTGACCATTATGAAGTGCGCTCTGTGCTCGGAGCTGTGCGACAATCGCATGGCCATGCAGCTGCATTTGGCCTGTGCCCACAGCCAGGAAACGAAGCTGCTGAGATGCAGTGCCTGCATGGAGCTCTTCCGTTCTGATGCAGAGTTCCATGTGCATGTTAAGACACGGCACCAATTGGCCCTGGGCAATCAGACCGGCGGCGGTCCAGGATCGGTGAACAGCGGAGTCAGTCCAGCCAATCCTCTCCAGTGTATGTTTTGCCGTGCCGTTTGCTCTTCGGAGCTGGAGATGCATTTCCATTTGGCTGCACATGCTCGACAATTCCGTTGTCCCTCCTGTCCGGAGACATTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCATGGAGGAGTGAAGGACAACAAGGAGCAGACGTCCCCGAATATGGGTAGTTTGTATGTGAATGCGTTGCTGCCTCCTCTGGCGGCGGCCGCTGCTGCAGCAGCGGTGACCAACAACAACAACAGCATCATTGACTACAATGTGGCATTCAAGTTCAAAGGTCTCTTTGGCGGAGCAGGCGGAGGTCCTCCCACGGCGGCCGCCAAGTTCTACAGTCCCCTGCAAGTGGATACGAAGGCCCAACAGGCCTCGCCCCACCCGGCCCTGATGTACGGACTAAGTCAGCGATACCTCATGGAAATGTATAAGGCCAAGTCCATTTCACCGGCTCCGGCACCTGCCAACGCGGAGCCGCAGCCAGGATCTGCCCCTGCTCCGCCACCGGCTACCTTCAGTTGCGGAATGTGCGAGCGTCAGGATCTACGCAGCGAGGCGGAACTTCACTCCCATCGCAAGCTAGCCCACAATCTTAAGACCGGCGTCAGTCTACGCTGCGCTTATTGTGCTGGCAATTTCAAGTCTAGGGCCGAGCTCGAGCAGCACATGAAGAGCTGCCACAACTCGACGGGCAAACACAAATGCCTGATTTGTGATGAGATATTTCCCTCGCCCGCCATCCTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGGCAGTCGGGCAAGTGTTCGCAGTGCTCGCATCAACTGGAGGATGTCGCCGCCTTCCGCAATCATCTCACGGAGCACGGAAGCGACGGAAGCCTGCCACTAGCCTGCATTTGCTGCCGCCAGACTCTGCACTCTGAATTCGAATTGTCCTTGCATGCCAAATTCCATACAAAATCATCGGTGGGCACTTCTAGGGGCAGCCTTCAGGAGCCAGTGTGTGCCTTGTGTCTGGAGCCGCTTCCGCCCACTGGACCCACAATTGACGGACACATTCCTGCCAAACTCTGTGAGAAGTGTTTGCGTAAGCACAATTTAAATGGTAAAAGAAACAAGCTGACGGAGTCTCCCTCGGTAAATGTGGCTTCGGCTACCGCCGCAGCTGTTCCACCTAACCATTCCCCCTTTCTGGAAAACCGCTGTAATCTGTGCAAAATGATTTTGCCCCATGCCCAAAAGCTTCAAGAACATCTGGTTGAACACACTTTCGCTGGCACCGAACAGCGTGGCTTCAATTGCTACATCTGCTCGGCAGTGTTCACTGCCCCGGGAGGACTACTCAATCACATGTCGGTGGAGCATGGGGCCCAATCGCGCCCCTACGATTGCAACTTGTGTCCAGAGAAATTCTACTTTCGAGCTGAGCTCGAGCACCATCAGCGCGGACACGAGCTGAGACCACCGCCAACTGCACGGCCATCTTTAACGAAACAGGAACCGCACTGCACCCTAATTAGTCCGAGTCTTAGCCCCACAACGGTTAAACTCGAGCTCTACGAATCGGAAACTCAGGCCTCTGATGCTGATGGTGCTGAGGAAGGGACTTCCAATGCTGCCCAGGAGGACGAGGAGTACATTGAAGTGGAGCAAATGCCACACGAAACACGGTCGGATGAGATAATGGAACGGTCTAGTAACAGCTCTTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSHHHLPASAATGLPEDHQTELKAHGDRDPKDPSQLFKPKRPSHFHHHHHHHYHHQQALKIANKLRKINKETNKMGSGTGTGTGPGSGTAAEDGGTGIGGASSDAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASVSSSNSSLHKRRYALALANNDSSSRSRSPSRLDYPKRSRINTNHSTPTPLLRCSYCPKVTEFSSLEQLNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSFELNCEYCTMKFGSIAGLFQHMRSTHLDRLSSPPSTIASYYEHFNRLEMPKQIKQDLSSPQRKAEEPEELPTDLSSNKRQMEEPTPAPAAGPVAAPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLTLPEQQEYERHVVAHFLITNSEFNCSSCGKSFAKAEDLQQHLLAEHVVTIMKCALCSELCDNRMAMQLHLACAHSQETKLLRCSACMELFRSDAEFHVHVKTRHQLALGNQTGGGPGSVNSGVSPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDNKEQTSPNMGSLYVNALLPPLAAAAAAAAVTNNNNSIIDYNVAFKFKGLFGGAGGGPPTAAAKFYSPLQVDTKAQQASPHPALMYGLSQRYLMEMYKAKSISPAPAPANAEPQPGSAPAPPPATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSQCSHQLEDVAAFRNHLTEHGSDGSLPLACICCRQTLHSEFELSLHAKFHTKSSVGTSRGSLQEPVCALCLEPLPPTGPTIDGHIPAKLCEKCLRKHNLNGKRNKLTESPSVNVASATAAAVPPNHSPFLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMSVEHGAQSRPYDCNLCPEKFYFRAELEHHQRGHELRPPPTARPSLTKQEPHCTLISPSLSPTTVKLELYESETQASDADGAEEGTSNAAQEDEEYIEVEQMPHETRSDEIMERSSNSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00618656;
90% Identity: iTF_00600586;
80% Identity: -