Basic Information

Insect: Drosophila sturtevanti
Gene Symbol: zfh1
Assembly: GCA_018150375.1
Location: JAECWJ010000599.1:461714-465970[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.1e-05 0.0022 18.3 1.4 1 23 147 169 147 169 0.97

2 14 2e-05 0.0014 18.9 0.1 1 23 258 280 258 280 0.98

3 14 0.00093 0.066 13.6 0.7 1 23 286 308 286 308 0.98

4 14 0.00013 0.0089 16.4 4.1 1 23 340 362 340 363 0.95

5 14 0.00052 0.037 14.4 1.9 1 23 392 414 392 414 0.95

6 14 0.0099 0.7 10.4 1.6 1 23 420 443 420 443 0.97

7 14 0.023 1.6 9.3 0.4 3 19 452 468 451 469 0.95

8 14 0.00014 0.0096 16.3 5.6 1 23 478 500 478 500 0.97

9 14 0.041 2.9 8.5 0.4 2 23 506 527 505 527 0.96

10 14 8e-06 0.00056 20.1 1.0 1 23 536 558 536 558 0.98

11 14 0.00091 0.064 13.7 0.1 3 23 566 586 564 586 0.97

12 14 4.8e-05 0.0034 17.7 0.5 1 23 592 614 592 615 0.95

13 14 0.14 9.5 6.8 0.2 1 23 625 647 625 647 0.96

14 14 0.0048 0.34 11.4 0.2 1 23 1177 1199 1177 1199 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.1e-05	0.0022	18.3	1.4	1	23	147	169	147	169	0.97
2	14	2e-05	0.0014	18.9	0.1	1	23	258	280	258	280	0.98
3	14	0.00093	0.066	13.6	0.7	1	23	286	308	286	308	0.98
4	14	0.00013	0.0089	16.4	4.1	1	23	340	362	340	363	0.95
5	14	0.00052	0.037	14.4	1.9	1	23	392	414	392	414	0.95
6	14	0.0099	0.7	10.4	1.6	1	23	420	443	420	443	0.97
7	14	0.023	1.6	9.3	0.4	3	19	452	468	451	469	0.95
8	14	0.00014	0.0096	16.3	5.6	1	23	478	500	478	500	0.97
9	14	0.041	2.9	8.5	0.4	2	23	506	527	505	527	0.96
10	14	8e-06	0.00056	20.1	1.0	1	23	536	558	536	558	0.98
11	14	0.00091	0.064	13.7	0.1	3	23	566	586	564	586	0.97
12	14	4.8e-05	0.0034	17.7	0.5	1	23	592	614	592	615	0.95
13	14	0.14	9.5	6.8	0.2	1	23	625	647	625	647	0.96
14	14	0.0048	0.34	11.4	0.2	1	23	1177	1199	1177	1199	0.97

Sequence Information

Coding Sequence: ATGAACAATCCGAGTTATGGTAGCATCCAATGGATACAACACCACGTCTCCACTGACGAGACGGAGGCGGACACAATAGACGCTGGCGGAGATGCCTATTTGGTTAATGACACTGCCACGGATGAGGATCTTGATCATATGGCGGCAGAGAATCTAATTTTTATGGCACGCGATGGTCAGCTGGATGGGATTATACCTGCAAGTGATGTAGAATCGGATGGTGCGGTGCTAGTCACGGCCGATGACACAACTTTGGCCTATGCTGATAAAACGTTTGATGATGGAGCCGAGGTGGTCACCGAGGAGGTCATCATCGATGATTGGGTTCAGCATCAAGGAGCTGAGCGGGTGGAAATTGCTGCAGAGCAAATAGCTGGTACTACAAGTTCCCAGGAGCTGTTGGATATGGAGCAGGATGAGTATACGGTTCTCCGTCCATATCCCTGTGATTTCTGCAGTCGCCGCTTCCGTAAGAAGGTCAGTCTCAACAATCATATGCAGGCGCATCAAAATGATCGGCCGCATCTCTGCAAGCTATGCGATGCCAATGTAGTAAATCCTACACCGGTGGCATCTCGTGGCAGGATAAGTCGTCTAAAGCCCAAAGAGGAAGCAACTCAGTATATTGTGATAACCGAGAATGTGCAGAGCGAACCAAACCAAGCGGTGATGACTACATCCACTTTAGTTGATCCTCCACCTGCCGTTGTAACTGCCAATGATCCTCCACAACAGCTTCTCAATTTTCCAGTGCTAGATGAGGGTAAACCGTTTGTGTGCCAGCAATGTGGTTTGGCATTTGCTCGTCAGAAGGCTCTCGTGTCTCACATAAAGAATCATCGCGTGGACTCACCTTTTGAGTGTAACCAATGTCAGGAGATGTTCTGGGACAATATGAGCCTGCAAGAGCACCAAAAAACGCATCAATTCGAGGAGAGCAATTCGGAGTATGATCCAGCTTCAGCCTCAGATAGTGGCAGCGAAACGGAACCGGATGAGCAACAAATTTATGGTGAATTCTATTGCAGCGAATGTGGCATTTCCTTTCACAGGCAAAATCTATTGCGTCGTCATGCCAAGGAGCATCATTTCAAATCGACCAATGGAACTTATCAACCTCCGAGCATTCAACAAAAAGCTGGCGGTGATCAGGAAAATGGCACAGATGCCCCGCACTGTTGTCATACGTGTGGTAAATCCTTTCCCAGCGCCCTCGAGTTGCTTGCCCATGCTGAGATTCATGCCCGTTTCCCGCCCTTTAAGTGTGTCCTGTGTGGGATGAGTTTCTATGAGGAACAAGCAATCAAGCGACATTTGCATACCCGCCATACTAACGAATTGAAGCCCAACTCTTGTGTGTTGTGCGGAAAGGAGTGCCGCGATAGGAAGGCACTTATAAAACACGCCTGGGATCATTCACGTGAGAAGTGTCACTCATGCTCCAAATGTGGTAAAAACTTCCATAATAAAGCGCGTCTAAAGCGTCACATGGCATCGCATAGGGATAAATCAGTGGTATGTGAGGTATGTCAAGAAGAATTTCCCGATGGACGCACATTATCGAATCATCGGCACTCACACAGCACCACATCGCCAGGGAAGCTATTTCCCTGTCACGAATGCGGTAAAACCTTTGGCTCACGCAGTTCCCAACAAATTCATGTGCGGATCCATACAGGAGAAAGACCATATGGATGTCGCTATTGCTGGAAGGCTTTTGCCGATGGCGGAACACTACGAAAACATGAACGAATTCATACAGGCGAGAAGCCCTATGCCTGCTCTGTCTGTCCACGTGCCTTTAATCAGCGTGTGGTTCTACGTGAACATATACGCTCCCATCACTCAGGATTGGATGTGACAAAAGGAACCTACCATTGCACTGTCTGCTCGGCAGACTTACCCTCATCTAATGAGCTTATACAGCATCTCATCCAGCATAGTGACTCAAACACGGCCAAGCAAAGGCAACCAATTACTGGTCCGCGAAAATATAAGCGACGCCGTAAGCTTCAGCCCCACGAAATAGCACAGTTGCGTGAAGATCATCAGGATGTTGAAACTGCCGTTGATGATGGTTTGGGTGAGGATGAGGGTGATGAATATGCCAGCGATATTGATATCTGCGATTTTGATATGGAAAATGTAGATGATATCTTTGAAATGGCATCCTCAACACATGCAAACAAAAAGGAAAAGCGCAAGAAAGCATCGGCAAAGGAGACGACGAAGCCACAACGGAATGGAACAGTGTCCAAGCCGGATGGTGGATTGGATCAGCAAAAATGCAAACAACGCTATGATTCTAATAGTAGTCAATCGGAACGTATGTGGGGCGATAAGCAGGATAATCAAGTGGCCTTCTTTCAAATTGATTCTCTGGTAGTTGTTAATGATACCACACTGGAGCCGGCAAGTTCAGTGAGTTGCCCGAATGGTAATGGCACAACAAGGACTCGCGGACGCACGGCCAAACAATCGGCACAGACGCAATCCAAGGGGCCAACTTCAACTGATAGTAAACCCGATGTCATTGCCCCATCCTCTGGCGGCTCAAGTAGTCGCGGTAAAAAGAAGACTGCCACCAAGCAGAGTACAGCCAGCGTCTCGCGTCCACGTATGATACACACTGAAAAGACCAAGGTAACACGAGCGGTTGCAGAGAGTTCTAGTGGTGGTGGAGGTGGTAAAAGGACTCGTGCCAAAACCTATATAACCCGCACGGAGACAAGCAATTTGGAATTGCTTGCAGGGAGCAGCGGAAAAACGAGTGCCTCATCGGCGGCTGCATCCAATATTGTGGACGATTATGAGATCATTTCCCCTGCCACACAGCCACCCAATCAGATAAGTTCCAGTCCCTTGCACATCAAACAGGAGCAGGAGCAGCAGCGTGTACAGTTAATGTACGAAGATACCCTTCTCATCGATGCGACACTTTTACGTGAGAAAACCTACGAGAAGTTTAATCCAAGTGTTGTTAATGATTTGGAGGAGATTCTTCGATCGCCACTTAAAAGTCGCATGCGTTTCACCAGTGAATCCTCAACAACGCCACAGTTCCTGCCCAATGAAGAGCAAAACCTTATCAAAATTGAGCCCACATCGCCAGATCTACGTGAAATGGTAGAGGGTCAACAGCGAGTTACAAATTGCATTGCCACACCCTCCTCCATTGCGTCCTCCTCGTCACCATCAACGGCATGTAATTCCCGTCATTTGCGTCAACTTTCTTCTAATAATCAGAGGGCGGGCAACAAACGATCCGGTGGTGGCAGCAGCAGCACAAGTACCAATAAGTCTGCATCAACATCGTCTACAACCAATGGGAAAAAACCCGTTCCATCCTCTTCCACATCCTACGGAGTAGGCGTTGATGCCTATAATGTTAATGTACCTGCCAATGCAAGCACTGCCGATGTGAGTTCCGGTTTCTTTTCCATTTCCGAGGTGGTCTCCGCTGCCGAAACAGCCGATGCTGCAGCCAAAGAAGCGGCGGCCGGCAAATCGGAGCGCAAGACACGTAGCTTTGAGTGTGAAATGTGTTCGGCTATATTCTATGATCGAGCCCAGCTATTGGAACATGTTCACATTCATATTTAG
Protein Sequence: MNNPSYGSIQWIQHHVSTDETEADTIDAGGDAYLVNDTATDEDLDHMAAENLIFMARDGQLDGIIPASDVESDGAVLVTADDTTLAYADKTFDDGAEVVTEEVIIDDWVQHQGAERVEIAAEQIAGTTSSQELLDMEQDEYTVLRPYPCDFCSRRFRKKVSLNNHMQAHQNDRPHLCKLCDANVVNPTPVASRGRISRLKPKEEATQYIVITENVQSEPNQAVMTTSTLVDPPPAVVTANDPPQQLLNFPVLDEGKPFVCQQCGLAFARQKALVSHIKNHRVDSPFECNQCQEMFWDNMSLQEHQKTHQFEESNSEYDPASASDSGSETEPDEQQIYGEFYCSECGISFHRQNLLRRHAKEHHFKSTNGTYQPPSIQQKAGGDQENGTDAPHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGMSFYEEQAIKRHLHTRHTNELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVTKGTYHCTVCSADLPSSNELIQHLIQHSDSNTAKQRQPITGPRKYKRRRKLQPHEIAQLREDHQDVETAVDDGLGEDEGDEYASDIDICDFDMENVDDIFEMASSTHANKKEKRKKASAKETTKPQRNGTVSKPDGGLDQQKCKQRYDSNSSQSERMWGDKQDNQVAFFQIDSLVVVNDTTLEPASSVSCPNGNGTTRTRGRTAKQSAQTQSKGPTSTDSKPDVIAPSSGGSSSRGKKKTATKQSTASVSRPRMIHTEKTKVTRAVAESSSGGGGGKRTRAKTYITRTETSNLELLAGSSGKTSASSAAASNIVDDYEIISPATQPPNQISSSPLHIKQEQEQQRVQLMYEDTLLIDATLLREKTYEKFNPSVVNDLEEILRSPLKSRMRFTSESSTTPQFLPNEEQNLIKIEPTSPDLREMVEGQQRVTNCIATPSSIASSSSPSTACNSRHLRQLSSNNQRAGNKRSGGGSSSTSTNKSASTSSTTNGKKPVPSSSTSYGVGVDAYNVNVPANASTADVSSGFFSISEVVSAAETADAAAKEAAAGKSERKTRSFECEMCSAIFYDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00501217;
90% Identity: -
80% Identity: -