Basic Information

Insect: Drosophila stalkeri
Gene Symbol: -
Assembly: GCA_035047405.1
Location: JAWNPR010000142.1:21680383-21684284[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00042 0.031 14.8 0.1 1 23 163 186 163 186 0.96

2 14 0.00021 0.015 15.8 2.3 2 23 235 257 234 257 0.97

3 14 0.013 0.93 10.2 0.9 1 23 355 378 355 378 0.93

4 14 0.61 45 4.9 3.9 2 23 427 449 426 449 0.95

5 14 0.0033 0.24 12.0 0.5 1 23 514 537 514 537 0.88

6 14 2 1.5e+02 3.2 0.1 2 14 556 568 555 580 0.85

7 14 0.0007 0.051 14.1 3.3 2 23 588 610 588 610 0.96

8 14 0.0013 0.094 13.3 0.1 1 23 714 737 714 737 0.95

9 14 8.6e-05 0.0063 17.0 0.3 1 23 789 812 789 812 0.93

10 14 0.0012 0.086 13.4 2.2 2 23 862 884 861 884 0.97

11 14 0.0013 0.092 13.3 1.4 1 23 972 995 972 995 0.92

12 14 0.14 10 6.9 1.5 1 21 1047 1067 1047 1068 0.95

13 14 0.28 20 6.0 0.2 2 23 1111 1134 1110 1135 0.86

14 14 7.3 5.3e+02 1.5 0.4 1 9 1153 1161 1153 1177 0.68

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00042	0.031	14.8	0.1	1	23	163	186	163	186	0.96
2	14	0.00021	0.015	15.8	2.3	2	23	235	257	234	257	0.97
3	14	0.013	0.93	10.2	0.9	1	23	355	378	355	378	0.93
4	14	0.61	45	4.9	3.9	2	23	427	449	426	449	0.95
5	14	0.0033	0.24	12.0	0.5	1	23	514	537	514	537	0.88
6	14	2	1.5e+02	3.2	0.1	2	14	556	568	555	580	0.85
7	14	0.0007	0.051	14.1	3.3	2	23	588	610	588	610	0.96
8	14	0.0013	0.094	13.3	0.1	1	23	714	737	714	737	0.95
9	14	8.6e-05	0.0063	17.0	0.3	1	23	789	812	789	812	0.93
10	14	0.0012	0.086	13.4	2.2	2	23	862	884	861	884	0.97
11	14	0.0013	0.092	13.3	1.4	1	23	972	995	972	995	0.92
12	14	0.14	10	6.9	1.5	1	21	1047	1067	1047	1068	0.95
13	14	0.28	20	6.0	0.2	2	23	1111	1134	1110	1135	0.86
14	14	7.3	5.3e+02	1.5	0.4	1	9	1153	1161	1153	1177	0.68

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCAATGTTTTCAGCCGATTTCGAGGAAGGTGATGGTGAGTTGGAGGGCCAAAATAATGGCAAAAACGCGCTTGCAGACGAGTTTATGGGCGATGAAGAGGAGGAAGAACATGAGGCTGAAGAGGATGAGGGGTCGGCAGACGACAGagacagcaaacaaaaaggaCACGAGCCCGATGACGATGccatatttgattttgaactAGAGCCTATTGTTAGCATTGCGGAACCAGAACTGGAACCGTTACCTAAACCAACGGCGGCCCCACTGCCCCTGCAGCCCCCAATGCCAACGGGTCCAGCCATCAGACCCCAGCACCGTCAGTCGTTGCCAGCCTCGTTTGGCTCACAGCAGATGGTGGGTCGTGGTGGTACAGGTATACCATCTACTCGGCCGACGACCTCACAGATCAATGCTACTGATGAGAACGGTGTGCCCATCAATTATGAACTCGGCGTTACCTATATATGCCCCGCATGTGGCGCAGAGTATCGGCAACAGGACATGTGGAAGCGTCATATGAACCAGATGCATCAGTACAATACCCGACGTGGTCTCAATTTCGTTGCCATTGATAAACTGTATCATCGGTGTCTGGAGTGCAACAAGCGGATCGCGATGCACAGCCGGGAAAATTTGCTAAAACACAAGTTCACCCATTTGCCATTTCGCTGTACCAAGTGCCACATATGCAAGCGCGAGTACAAATACAGGCAGGACCTGATGGTACATCTCCGAATGGTGCATTGTGATGAGGTGATAGCCATGATGCGAGGTGGCAAGTTGAGTGCTGGACGCAAAACGCGTGTTCGTGAGCCCCGCATCGAACAGCACCGCGAACAGTACGACGAGGAAGGCGTGGAGGTCAAGAATGAGCTGATGGAAGCAGATGACAGTGGGGAGCCTGCTCAGGAGTCCAAGCATGAGTTGGATGATGAGTACAGTTCCAGTTCTAATCAAGCGGTTACAAAAAAGCGTAATACTTCTGTGACGGGCAATGGTAGCGGTGCAGCAGATATTTGCGAGGactatatacattatatgtgCCCTGATTGTGGCACCGATTGCGATACCCATGCTCAGTGGAGTCAGCATATTGAATTTGTGCATGATTACGTCAGTCGGAGGGGGCTGAACTTTCGGTGCGTGGATATGCAAATGCAGTGCCTCGAGTGCAAACAGTTTGTCATTCCGAACACCATTAAGACGCTGCGCGCTCACAAGTTCAGCCATTTGCCGCAGCCGGAGTGGATGCGCTGCAAGCTGTGCTATAAGGGCTTCACAGAACACCATGAAATACTGACCCATCTTCTTAAACAGCACAATTTGGAAACTCTAATGCctgagaaggaggaggaggagcagcagcagcctttgGCTATATTGAGTGTGGGTGATGAGTGTGAGGAGATTCCTGGCATTGGCTGCGATGAAGAGACTTCATTGCATTGGGACGATTTGCCTCGTCGTGGTGGTCGTATCGGTTGCGATGATATGTATGAGCCGCATATTGATTATCTCTGTCCGCAGTGCGGCAGGGAGTTCATAGAGAAGAAACATTGGCGCACCCATGTTGTGCAAGTGCACGGTATGAATGATCTGACCAAGTTGAATTTTGAGGTTATTAACGATCGCCAGTTGAAATGTACCGAGTGCGATAAAATCATAACGAATGCCTATGGTATACAGAATGCCCAGCAGCACAGGATAACGCATTTGCCATACAAAGCCTACGCGCGATGCCGCAAGTGCCACAAGTCCTATACGGATCGTAAGGGCCTTGTCAAACACTTGGCCACATACCATCGCGTGGGCTACGAGCCCCGCAAAGTGGTTGGAAGTGGAACAGGCGTTGCTACATTGACACCAACCAAACCACACACGCCTCGCAAGCAAATTGTCACCGTGGCCAATGAGACTTATGAGATTATCTATTTGGATGAGGAGCAATCACCGcccagtaataataatataaatgaagagAATGATTTCGGCGAGCAAATGCAAGCGGACGATGATGACTATGCCGTAGTCAGCACCAGTGGCACAATGGGACGCCAGCCACAAATACCCACACTTGCTGCAGCACCTAATCCTAATCCTAATCCGAATCGTTATAAATGCGTCGATTGCGGTTCGCTGTTTGCCACGCAGGTGGCATTAAAGACGCACATAAGCGAGGAACATGATTTTATGGACACACAATACAGTGCCAAAAAGTTTGACAATGCGGAGCCCACTGAGgaggcagctgcagcgcgTGTTGTTGTTCCAGCCAGTGCCGGTAGTACGCCTATAAAGAACACCTCAGGCGCTTCTACCATAgagcaaaattatatattcctgTGCCCGTCGTGCGGGAAGGCATACAAGACGCAGTTCGAGTGGCGACGTCATATCAACGAGGAGCATAATTTCGACAAACGacagtatttaaatatgcgcCAGCTGGACAAGTATCGCTATCAGTGCACCCTCTGCAAGGATGTTGTGTGTAACTCGAAGCTGAAAGGTCTGCAGGATCATCATTTTCGTCATCTGCCTTACCGCCTATATCTGAAGTGCCTGGTGTGTGGCACCTGCTACAATCACAAGCCCAATATAGCAGCGCATCTGCGCACGCGACACAACATCTACGAGCGCGAGTCCTCATCGTGGCGTGACCAGCACCAAAAGACCCAGAATGGCCACGAGCAGCAGAATAATAAGGATAAGGATAGGGATCCGCAAGCCCCTGCAGCCACTGGCACGACTTCTGCTTCACCTACACCCGGCAGCAGTCGCACGCTCAAGCCTCAGCCGGGCGTGTTGCCCACACGACCCGCTGGGCTCAACACGCTGGAGGATAGCATATCGTATCACAATGCCGTGGATTTGGACTTTATTACCTATTACTGTCCCAAGTGCAATAAGAACTTTGACTCGCATGCCTTTTGGCGTAAGCACATAGTGGAGGTGCACAACTATAACAGTCGGCAAGGCCTGAACTTTCGCCAGATTGACAACCATCACTATCTGTGCCTGGAGTGTTATAAGCGTGTGACTGTGACGCACACTAAAGGTGCTATTGGGCAGCTGCAGTCGCATAAGTTCCGTCATTTGCCCTATCGCTCCTTCAAGTGCTTGACCTGCAGCGGGGAATTTGTGCGCAAGCAAATGTTCTTCAAACACTTGAACCGCGACACCAATCGTTGCGACAACAAGCCATTGAGTGGCCAGGAGAACGATGAGGATACCGCAGATCAGCCGGACAGACCAGCTACCACGCTCGCAAAGGAGACTTTAGATGTCGCTACGTATCGTTTGATATGTCCACAGTGCGGCGACGAGTtcaccaccagcagcaaagCTCTGTGGCGAGAGCACATTAATATACATCATGGTCTGGGGAAACGGGAGATGCTGCACATGCGCAAGCTAGGCGATGAATTGTATCGCTGCACAGATTGTGAAGAGCAGCTGCAAACGAAGCAGCTGCGAGTGCTCCAGCAGCATCGCTTCCAGCATTTGCCCTATGCCGCATATATACGTTGCCAGCTATGCGAGCAGCAGTCGTCGGATGGCGTGGGTCATGGTGTAGCAGCTGCGGGATTACATAGCATGCGTGAACTGCAACAGCACATACGCAACGAACATCCGGATGTGTTGGAGCAGGACGAGCAAGTGCAAGCACTGCTTGACGAGGAGGAGGATAGTCAACAGCCGGCGATTAGTGGCGAAGCAACAGAGACTGGACTGTATATGCCGCTGCCACCGCATTTGCTAGACGACGATGTAGAGGACATGGAGTTCGAGGAACAGTATCTGCTAGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDGELEGQNNGKNALADEFMGDEEEEEHEAEEDEGSADDRDSKQKGHEPDDDAIFDFELEPIVSIAEPELEPLPKPTAAPLPLQPPMPTGPAIRPQHRQSLPASFGSQQMVGRGGTGIPSTRPTTSQINATDENGVPINYELGVTYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCHICKREYKYRQDLMVHLRMVHCDEVIAMMRGGKLSAGRKTRVREPRIEQHREQYDEEGVEVKNELMEADDSGEPAQESKHELDDEYSSSSNQAVTKKRNTSVTGNGSGAADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLPQPEWMRCKLCYKGFTEHHEILTHLLKQHNLETLMPEKEEEEQQQPLAILSVGDECEEIPGIGCDEETSLHWDDLPRRGGRIGCDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLTKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKVVGSGTGVATLTPTKPHTPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAVVSTSGTMGRQPQIPTLAAAPNPNPNPNRYKCVDCGSLFATQVALKTHISEEHDFMDTQYSAKKFDNAEPTEEAAAARVVVPASAGSTPIKNTSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDVVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESSSWRDQHQKTQNGHEQQNNKDKDRDPQAPAATGTTSASPTPGSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEVHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTNRCDNKPLSGQENDEDTADQPDRPATTLAKETLDVATYRLICPQCGDEFTTSSKALWREHINIHHGLGKREMLHMRKLGDELYRCTDCEEQLQTKQLRVLQQHRFQHLPYAAYIRCQLCEQQSSDGVGHGVAAAGLHSMRELQQHIRNEHPDVLEQDEQVQALLDEEEDSQQPAISGEATETGLYMPLPPHLLDDDVEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00493954;
80% Identity: -