Basic Information

Insect: Drosophila stalkeri
Gene Symbol: ush
Assembly: GCA_035047405.1
Location: JAWNPR010000039.1:9292008-9298415[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0068 0.5 11.0 0.0 1 20 238 257 238 259 0.90

2 9 0.00029 0.021 15.3 0.8 1 23 314 336 314 336 0.98

3 9 0.052 3.8 8.2 1.0 2 21 381 400 381 401 0.92

4 9 0.051 3.7 8.3 2.9 2 21 780 799 779 800 0.93

5 9 0.0094 0.68 10.6 0.0 3 21 848 866 846 867 0.91

6 9 0.0068 0.49 11.0 0.0 2 23 926 947 925 947 0.98

7 9 0.004 0.29 11.8 1.3 1 23 953 975 953 975 0.99

8 9 0.0014 0.1 13.2 1.9 1 23 1038 1061 1038 1061 0.96

9 9 0.31 23 5.8 0.7 2 20 1168 1186 1167 1188 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0068	0.5	11.0	0.0	1	20	238	257	238	259	0.90
2	9	0.00029	0.021	15.3	0.8	1	23	314	336	314	336	0.98
3	9	0.052	3.8	8.2	1.0	2	21	381	400	381	401	0.92
4	9	0.051	3.7	8.3	2.9	2	21	780	799	779	800	0.93
5	9	0.0094	0.68	10.6	0.0	3	21	848	866	846	867	0.91
6	9	0.0068	0.49	11.0	0.0	2	23	926	947	925	947	0.98
7	9	0.004	0.29	11.8	1.3	1	23	953	975	953	975	0.99
8	9	0.0014	0.1	13.2	1.9	1	23	1038	1061	1038	1061	0.96
9	9	0.31	23	5.8	0.7	2	20	1168	1186	1167	1188	0.91

Sequence Information

Coding Sequence: ATGGCTGCATACAACGCCcaccagcagccgcagcagcagcaacagcaacagcaacagcaacagcggcaacaatgcTGGCCAAGTGAGAAACCAGCAACAATAATCTGCCGGCTGATAAAACGAAGCATCTCCTTGGCCCCGCTGCCCTTGCCATGGCCACAGTCCTCAAGCttcgtgtATTCCAAAGACTTGGGCGCACACGAGCTGAGCGAggagaaacagcagcaacagctggacGAGCAGCCCGAGgacgagcagcaggagcagcaagcTAGCAACGCCTCTGAGCAGCTGGAGGAGACTGACATGGATCAGGAAATGGTCGAGGAGGAGCAGGCAGCGGCCCAGGAGGCAAGTGCACAGCAGCAGAATGTGGCCGACAGTTCGACGACTCCGCCGCGTAGTCCAACGCCAGCCGAGCTGGTGCCCAAGCTGGAGCGTGTTGATTCGCCAGCAACGCCGCCTTCGGTGGCCGCCACGCCCAGTCCACCACCAACTCCCACGCCGCCGTTGGTGCTGCCCAAGCTACGTCTCAATGCGCTGCTCGCTTCCGATCCGGCACTGAAACCCGATGCCAAGGAGCTCAATCTCGAATCACGCTTGCTCGGTCCGCCGCCACAGCTGGTCAAgcctgagcagcagcagcaacagcagcaacagagttTGCCCGATCCCAGCAGCCTGGTGGAGCCGCTGCTCAAGCCGGCGCGCTTTATGTGTCTGCCCTGCGGCATAGCCTTCAGCTCACCCTCAACTCTGGAGGCGCACCAGGCCTACTATTGCTCGCATCGCAACAAGGATGCCGACGAGGACTCCACCGTTGGCGATAAaggcgcagctgcagctggcggCGGCTCCAATCCGAATGCCAACAGCAGCTCCAGTGGCGCCAGCTCCGGCTCAGAGCCACCCGCCAAGGTGGCGCGCACTGGCAAGCAGTACGCCTGCACCCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTCAACCGGCACATGCGCATGCACCAGACCTCGCCCGCCGCCCCCACCTTGAACAGTCTATCCGGGCTGGCGGCAAACGGTGTGGtggctgccgccgccgctgccgctgctgcggcCAGTGCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTATTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTATCGCGCCCACAAGCAGCACTACTGCAGCTCGCGGCGCAGCGATGGCCAGCTGACGCCCAAGCCTGAGGCAAATGCTAACAGCAACTCCGGCTCCAGCTCTGCACCGGGAGCTGCGGTCACAGGAGCTAAGCACAGTGGAGCTCACAGTCCGCAGACCCGCAACAAGACGCCTACGCCTGCCATGgtcgctgcggctgcggctgcggcggccgctgctgcagctgctgcctcgCTGCAGGTGTCACCACCGCAACCCTTCCTGGCACTGCCCACTAATCCCATCATCATAGTGCCCTGTTCGCTGATACGCGCCGCCAGTCTCATACCCGGACCACTCACCACCTCCACGTCGGGCATTGTCAATCCGGAGTCCACATGCTTTACCCTTGATAATGGCGCACTCAAACCGCTGGCCACGGCGCTCAATATAAACGCGCTGGCGagcaatgccacgcccacgcccacagccacgcccatgccAAGCAGCAATCAGCTGAGCATGCCCGCCCTGGAGCCCGAGCGTCCCAGCGCCAGCAGCGTCCTAGAGCCAGAGTCCAAGAGCAGTCCGCCAGAGCCCAAGCGCAAGGAAGCCAGTGGCATGCGCGATACCACACCCCTAGACCTATCCCTACGCCGTTCGCCCATTTCaccgctgctgcagcgccaGCGTCTGATGGAGGAGGCGCTGCTCAGTGCCGGCAAGGAGAACATGGAGAACAGCAGCCGAACGGGAGGCAGTGTTACGCCGGAGCAGATTGTATGCGCACCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCGTCACCCAAGCGACGTGCAATCAGTCCGCGCAGCTCGGGCGCAGGCAGCGCTGCCTCCATGTCGCCGCCAGCGTTGGCAATGCCGCATCTGCTCGACAATCTGCAGCCATTGCGCTCGATGTTGCCCGCCGATTTTGCGCTATCCGAATCGCTGCTGGCCAAGACCAATCCGGAGCTGGCACTCAAGCtggccgcagctgctgcagcagctgtggcagGAAGCAGCACCGCTGAGCTGGCTAGCAAGCTGGGCTTCAGTCCAGCCACGGCCGCTGCGCCTCCTTCAGCTGTGCCCAATGTTGCAGCGAGTGCACCCAACAGCCAGCCGCAGATCTATGTGAAACAGGGCGTGTCCAAGTGCAAGGAATGCAACATAGTCTTCTGTAAGTACGAGAACTACTTGGCGCACAAGCAGCACTACTGCTCCGCGCGCAACCAGGATGCAGGTGTGGATGGTGACTCAAAGAATGCTGTAACGCCGCCCGCTGCAGCGGGCCCAGGCGTGCCTGCTGGCGCCTCCTCCTTGGAGACAACGCCCGTGGCCTATCAGCAGCTGATCTGTGCCGCCTGCGGCATTAAGTACACCTCACTGGACAATCTGCGTGCTCATCAGAACTATTATTGTCCCAAGGGCGGAGCAGCAGCCACTCCAGCCGAAGCGGCGACGccacagctgccgctgcccaaGGAGAAGTGCGTCAAATGCAAGACGCTGCACGAGCACGGCCAGCCCTGTCCAACACCCCCGGCCACGCCCCAGCTGGCGCCGGCCAGTGTGGCGAACAGCGTGAACAAGTGTCCAGTGTGCGGCGTGGTCAGCCCCACTGCGGCGCTGGCTCGCAAGCACATGGAAATGCACGGCACAGTGAAGGCATTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGCGGCATGCGCACCCACATACGCACCCACTTCGATAAGAAGACCAGCGACGTCAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGATGCCTCAGCgcaagcggcagcagctgtagctgcagcagTGGCTCAGCCACCCCCAGCCATGGGTTTGGATCTGCCCGCAGTGACGGCGGCCCAGGAACAGCTGGAACAGCATGCGGCACAGATCTTCAACTGCGATCATTGCAACTATGCCTCCACCTACAAGGGTAATGTGCTGCGCCATATGAAACTGTTGCATCCACATGTGGCAATTAGCTCACCCTCCATCTCACCCGAGTCCCGAGAACAGGATACCAATGCTCATGCTCTGCCCGAGGTAGCTCTGGTAAATGGCGAACGCGAGGCGGGCAGTTTTCACATTAAGTCGGAGCCCTTGGAGCCAGCTGTGGCCACGCTGAGTCTGGTGCACGAGAACAATAATTCGCCCATTGGCACGCCGCACACGCACATCAAAGCTGAGCCCCTGGACATGGGCATAGAGTTGACGCCAGCCACACTGCCACCACCCATTGCCAATTCGCCGCTGGGGCCAAGCGCTGCGGAGGCTATGAAGAAATACTGTTCCACCTGCGACATATCGTTCAACTATGTGAAGACCTTTTTGGCGCACAAACAGTTCTACTGCAAGAGCAAGCTGCATCGACCGGAGGCCAGTGATAGCCCCAGTCCCACTGTAGGCGTCGGTGGGGCCGCCATGCCGCTGCAATCGCCCAGCgagctgatgttgctgcagaAGAACAAAGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MAAYNAHQQPQQQQQQQQQQQRQQCWPSEKPATIICRLIKRSISLAPLPLPWPQSSSFVYSKDLGAHELSEEKQQQQLDEQPEDEQQEQQASNASEQLEETDMDQEMVEEEQAAAQEASAQQQNVADSSTTPPRSPTPAELVPKLERVDSPATPPSVAATPSPPPTPTPPLVLPKLRLNALLASDPALKPDAKELNLESRLLGPPPQLVKPEQQQQQQQQSLPDPSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEDSTVGDKGAAAAGGGSNPNANSSSSGASSGSEPPAKVARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPTLNSLSGLAANGVVAAAAAAAAAASALEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEANANSNSGSSSAPGAAVTGAKHSGAHSPQTRNKTPTPAMVAAAAAAAAAAAAAASLQVSPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALASNATPTPTATPMPSSNQLSMPALEPERPSASSVLEPESKSSPPEPKRKEASGMRDTTPLDLSLRRSPISPLLQRQRLMEEALLSAGKENMENSSRTGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSAASMSPPALAMPHLLDNLQPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSTAELASKLGFSPATAAAPPSAVPNVAASAPNSQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQDAGVDGDSKNAVTPPAAAGPGVPAGASSLETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPAEAATPQLPLPKEKCVKCKTLHEHGQPCPTPPATPQLAPASVANSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDASAQAAAAVAAAVAQPPPAMGLDLPAVTAAQEQLEQHAAQIFNCDHCNYASTYKGNVLRHMKLLHPHVAISSPSISPESREQDTNAHALPEVALVNGEREAGSFHIKSEPLEPAVATLSLVHENNNSPIGTPHTHIKAEPLDMGIELTPATLPPPIANSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEASDSPSPTVGVGGAAMPLQSPSELMLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598429;
90% Identity: iTF_00532635;
80% Identity: -