Basic Information

Insect: Drosophila stalkeri
Gene Symbol: L
Assembly: GCA_035047405.1
Location: JAWNPR010000090.1:14008349-14017942[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 1e-05 0.00075 19.9 2.9 1 23 167 189 167 189 0.98

2 16 0.35 26 5.6 6.2 1 23 195 217 195 217 0.97

3 16 1.7e-07 1.2e-05 25.5 3.2 1 23 223 245 223 245 0.99

4 16 1.3e-05 0.00091 19.6 0.4 1 23 251 273 251 273 0.99

5 16 0.014 1 10.0 0.2 2 23 352 376 351 376 0.93

6 16 0.00031 0.022 15.2 0.2 2 23 398 420 397 420 0.96

7 16 0.073 5.3 7.8 0.3 2 23 519 540 518 540 0.91

8 16 0.021 1.5 9.5 1.2 3 23 551 573 548 573 0.86

9 16 3.4 2.5e+02 2.5 1.0 2 23 609 631 608 631 0.95

10 16 0.0025 0.19 12.4 1.1 1 23 675 698 675 698 0.97

11 16 0.0065 0.47 11.1 1.6 2 23 881 903 880 903 0.96

12 16 0.12 8.4 7.2 0.1 1 23 909 931 909 931 0.92

13 16 0.55 40 5.0 0.4 2 23 939 960 938 960 0.93

14 16 0.31 23 5.8 1.3 1 23 1059 1081 1059 1081 0.94

15 16 0.02 1.5 9.6 0.0 1 23 1091 1113 1091 1113 0.96

16 16 0.00022 0.016 15.7 1.2 1 23 1118 1140 1118 1140 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	1e-05	0.00075	19.9	2.9	1	23	167	189	167	189	0.98
2	16	0.35	26	5.6	6.2	1	23	195	217	195	217	0.97
3	16	1.7e-07	1.2e-05	25.5	3.2	1	23	223	245	223	245	0.99
4	16	1.3e-05	0.00091	19.6	0.4	1	23	251	273	251	273	0.99
5	16	0.014	1	10.0	0.2	2	23	352	376	351	376	0.93
6	16	0.00031	0.022	15.2	0.2	2	23	398	420	397	420	0.96
7	16	0.073	5.3	7.8	0.3	2	23	519	540	518	540	0.91
8	16	0.021	1.5	9.5	1.2	3	23	551	573	548	573	0.86
9	16	3.4	2.5e+02	2.5	1.0	2	23	609	631	608	631	0.95
10	16	0.0025	0.19	12.4	1.1	1	23	675	698	675	698	0.97
11	16	0.0065	0.47	11.1	1.6	2	23	881	903	880	903	0.96
12	16	0.12	8.4	7.2	0.1	1	23	909	931	909	931	0.92
13	16	0.55	40	5.0	0.4	2	23	939	960	938	960	0.93
14	16	0.31	23	5.8	1.3	1	23	1059	1081	1059	1081	0.94
15	16	0.02	1.5	9.6	0.0	1	23	1091	1113	1091	1113	0.96
16	16	0.00022	0.016	15.7	1.2	1	23	1118	1140	1118	1140	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGCTGTATCGCGGTCCCAGTTCGCGTTTagagaatttaattgaaaagatTCAAGCGACCAAGGAGATAACTAATAACGATATGTACAGCACGCACACTTCCTCGAGCTACTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAActcacagctgcagcagccgcagcactcgcaacagtcgcagcagcagcagcaagcacaggagcagcaggaggcgggcgaGGAGGCGGCCAAGGCAAATGGTGATGCTGCACAGCAAAcagagctggagcaggagctgagCAAGCCAAAGCGACCGGCACAtttgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATAGCGAACAAGCTGCGCAAAATCAATAAGGATGCAAAGCTGGCTGCAGGACAAGGACAAGGACATGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAACATCACGTGCAGAGCCATGCCGAGCATTTGCCTTTCAAGTGCGAATACTGCGCGAAGCTCTTCAAGCACAAACGCTCACGAGATCGTCATAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTGAAGATTCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCTCTCACCTCCCACATGCAGAAGCATAAGAAGAATGCCGCAATTCTCGCAGCTGGCGGTAATCCCAATGCACTCAACTATAGTCCACGCTCCACGGGCTCTGCCTCGATATCGAGCAATGGCAGCTTGCATAAGCGTCGCTATGCCTTGGCTCTGGCCTCCGATAGTAGTCCCAGTCGCCTGGAGTTTCCCAAGCGAGCGCGTGGCCAGCTGACGACCACGCCCACGGCCACAACaatagccacgcccacgccgcTGCTGCGCTGCAGCTACTGCCCGAAGGCGACGGAGTTCAGCAGTCTCGAGCAGCTAAATGCGCATTTGCAGAGCAcacacgagcagcagcagcaggagcagcagcagaaggatTCCGAGGGTCAGACGAATGGCTTTCAATTGAGCTGCGAATATTGCACGATGAAATTTGTGAATATCGCTGCGCTCTTCCAGCACATGAGAGTCACCCACTTGGATCGTCTGAGCAGTCCCAATTCCTATTACGAGCACTTCAATCGCCTCGGCTCGCCGCAGTCGAAGCTAATCAAATCGGATCTAACGCCATCGGAGAAGCCCGAGCAGGAGTTGCCCACAGATCTGAGCAGCAACAAGCGACGTCCACTGACCTCGCccacccagcagcagcaacagcagcaacagcagcagcagcagcaacagcagcaaccagcagcagcagcaaccggcGCCGCCGCCTCCTggcattttcttttgcaatcAAGTCACATAGCCGAGGGCATGCAGCTAATCTGTCCCCACTGTGGCCTCAGTCTGCCCGAGCAGTGTGAGTATGAACGCCATGTCGTTGCCCACTTTCTGATCAGCAGCTCGGAGTTCAATTGCTGCAGCGCCAGCTGTGGCAAGTCCTATGCCAAGGCCGAGGAACTGCATCAGCATCTGCTGGCCGAGCACGTGCAGACAATGCTGAAGTGTGTCCTCTGCTCGGAGCTCTGCGAGAATCGCATGTCGATGCAGCTGCACTTGGCCTGTGCACACAGCCAGGAATCGAAGCTGTTGCGCTGCAGCGCCTGCCTGGAGCTCTTTCGCAACGATGCCGACTTCCATGTGCATGTGAAGACACGCCATCAGCTAGGCAATCAGGGTTTGGCCGGCAATCCACCAGCTCCAGCCAATCCGCTGCAGTGCATGTTCTGTCGTGCCGTCTGCTCATCGGAGCTGGAAATGCATTTCCATTTGGCGGCGCATGCGCGACAATTTCGCTGTCCCAGCTGCCCGGAGACATTCCATGTGGAGTTCCTGCTGGACAGGCATATGCAGAGCCAGCATGGCGGCATCAAGGACAAAGAATCACCTGTGGCAGGTAGCATGGGCAGCTTGTATGTGAATGCATTGTTGCCACCTttggcggcagctgctgctgccgctgcagcagcaacaaatgccaacaacaataacaataataacaataacaacattgaCTATAATGTCGCCTTCAAGGGTCTCTTTGGTGGCAATAATCCGCCGAGCAAGTTCTACAATAGTCCACTCCAAGTGGACACCAAACAAACACCGCATCCAGCCCTGATGTATAGCCTGAGCCAACGCTACTTGATGGAAATGTATGCTGCCAAGGCCAATTCGCCAGCGATTGCCAGTGGAGCAGTGGAGCTGGCCACACAGCAGGCCATGCAatccgcaacagcagcaagcggcagcagcagcaacaacaacaacaacaacaacaacagcaacagcagcaacaacaacaacagctacagttGTGGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCTGAACTCCATTCACATCGCAAGCTCGCCCACAATCTGAAGACAGGCGTCAGTCTGCGCTGTGCCTACTGCTCGGGTAACTACAAGAGCCGCGCCGAGCTGGAGCAGCACATGAAGAGCTGTCATAATTCGAGCGGCAAGCACAAGTGTCTCATCTGCGATGAGATCTTTCCCTCTCCCGCCATTCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCCGGCAAGTGTGCCCACTGtggccagcagctggagcatgTGGCCGCGTTTCGTGCCCATCTGGGCGAGCATGGCAACGATGGCAATCTGCCGATGGCCTGCATCTGTTGCCGCCAGACTCTACACTCGGAATTCGAGCTGAGTTTGCATGCCAAATTCCATACCAAATCGCCCGGTTGCAATAGCCTGCAGGAGCCCGTCTGTGCCCTTTGCCTGGAGCCGCTGCCCGGCGCCGGTGAAACTGCCAAATTGTGCGACAAATGTTGCCGCAAACACAATCTGAATGGCAAGCGCAAGGAGCAAGTGCAGCCACAGGCTAtcgctgctccagctgcagctgcaattgcagccaGCGCCTATCTGGAGCATCGCTGTAATCTTTGCAAAATGATCTTGCCCCACGCCCAGAAGCTACAGGAGCATCTCGTCGAGCACACTTTCGCCGGCACCGAGCAGCGTGGCTACAATTGCTACATCTGCTCCGCTGTCTTCACGGCGCCCGCTGGCCTGCTCGCCCACATAGCGGAGCACGGCACACGTCCATACGATTGCAACTTGTGCCCGGAGAAATTCTATTTTCGCGCCGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGCGTGCACAGTCGGCCCCAATACGTCCACCCAAGCAGGAGACGCACAGCTCAACGGAAAGTTCCCCAGTGACGCTCAGTCCCAGCCATGTGAAGCAGGAGCTATACGAATCGGAGCCAGCTAATTCACCCAACAACGCTGATCTGCccgtgcagcagcaggaggaggaggaataCATTGAGGTGGAGCAAATGCCGCAGGAGACGCTGCGAGCTGGCGAACAGCTGAGCACCGAGCGttccagcagcagcgcctaa
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQLQQPQHSQQSQQQQQAQEQQEAGEEAAKANGDAAQQTELEQELSKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTTTPTATTIATPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQQQEQQQKDSEGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQSKLIKSDLTPSEKPEQELPTDLSSNKRRPLTSPTQQQQQQQQQQQQQQQQPAAAATGAAASWHFLLQSSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDADFHVHVKTRHQLGNQGLAGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVAGSMGSLYVNALLPPLAAAAAAAAAATNANNNNNNNNNNIDYNVAFKGLFGGNNPPSKFYNSPLQVDTKQTPHPALMYSLSQRYLMEMYAAKANSPAIASGAVELATQQAMQSATAASGSSSNNNNNNNNSNSSNNNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQVQPQAIAAPAAAAIAASAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPAGLLAHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRAQSAPIRPPKQETHSSTESSPVTLSPSHVKQELYESEPANSPNNADLPVQQQEEEEYIEVEQMPQETLRAGEQLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516498;
90% Identity: iTF_00502755;
80% Identity: -