Basic Information

Insect: Drosophila hamatofila
Gene Symbol: L
Assembly: GCA_035045345.1
Location: JAWNPA010000012.1:14808056-14818454[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.0008 19.9 2.9 1 23 167 189 167 189 0.98

2 17 0.37 28 5.6 6.2 1 23 195 217 195 217 0.97

3 17 1.8e-07 1.3e-05 25.5 3.2 1 23 223 245 223 245 0.99

4 17 1.3e-05 0.00098 19.6 0.4 1 23 251 273 251 273 0.99

5 17 0.015 1.1 10.0 0.2 2 23 352 376 351 376 0.93

6 17 0.00033 0.024 15.3 0.2 2 23 399 421 398 421 0.96

7 17 0.066 4.8 8.0 0.7 1 23 494 516 494 516 0.97

8 17 0.077 5.7 7.8 0.3 2 23 524 545 523 545 0.91

9 17 0.022 1.6 9.5 1.2 3 23 556 578 553 578 0.86

10 17 3.6 2.6e+02 2.5 1.0 2 23 614 636 613 636 0.95

11 17 0.0027 0.2 12.4 1.1 1 23 680 703 680 703 0.97

12 17 0.0068 0.5 11.1 1.6 2 23 873 895 872 895 0.96

13 17 0.12 9 7.2 0.1 1 23 901 923 901 923 0.92

14 17 0.58 43 5.0 0.4 2 23 931 952 930 952 0.93

15 17 0.33 24 5.8 1.3 1 23 1049 1071 1049 1071 0.94

16 17 0.02 1.5 9.6 0.0 1 23 1081 1103 1081 1103 0.96

17 17 0.00023 0.017 15.7 1.2 1 23 1108 1130 1108 1130 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.0008	19.9	2.9	1	23	167	189	167	189	0.98
2	17	0.37	28	5.6	6.2	1	23	195	217	195	217	0.97
3	17	1.8e-07	1.3e-05	25.5	3.2	1	23	223	245	223	245	0.99
4	17	1.3e-05	0.00098	19.6	0.4	1	23	251	273	251	273	0.99
5	17	0.015	1.1	10.0	0.2	2	23	352	376	351	376	0.93
6	17	0.00033	0.024	15.3	0.2	2	23	399	421	398	421	0.96
7	17	0.066	4.8	8.0	0.7	1	23	494	516	494	516	0.97
8	17	0.077	5.7	7.8	0.3	2	23	524	545	523	545	0.91
9	17	0.022	1.6	9.5	1.2	3	23	556	578	553	578	0.86
10	17	3.6	2.6e+02	2.5	1.0	2	23	614	636	613	636	0.95
11	17	0.0027	0.2	12.4	1.1	1	23	680	703	680	703	0.97
12	17	0.0068	0.5	11.1	1.6	2	23	873	895	872	895	0.96
13	17	0.12	9	7.2	0.1	1	23	901	923	901	923	0.92
14	17	0.58	43	5.0	0.4	2	23	931	952	930	952	0.93
15	17	0.33	24	5.8	1.3	1	23	1049	1071	1049	1071	0.94
16	17	0.02	1.5	9.6	0.0	1	23	1081	1103	1081	1103	0.96
17	17	0.00023	0.017	15.7	1.2	1	23	1108	1130	1108	1130	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTAgagaatttaattgaaaaaattcaaGCCACCAAGGAGATAACTAATAACGATATGTACAGCACGCACACTTCGTCGAGCTATTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAActcacagctgcagcagtcgcagccgcagcagcagcaacaacagcaatcgcAGCCCGGTTCGGAGGAGGCGGGCGAGGAGTCGGCCAAGGCGAATGGCGATGCTGCACAGCAAacggagctggagcaggagctgaaCAAACCGAAGCGACCGGCACAtttgcatcatcatcatcatcatcattatcatcatcagcaggCGCTGAAAATAGCAAACAAGCTGCGCAAAATCAATAAGGATGCAAAACTGGCTGCAGGACAACAAGGACAAGGACATGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTGCAGAGTCATGCCGAGCATTTGCCTTTCAAGTGCGAGTACTGCGCGAAGCTCTTCAAACACAAACGCTCGCGAGATCGTCATAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACAGCCGCCGCCCTCACCTCCCACATGCAGAAGCACAAGAAGAATGCCGCCATCCTGGCAGCTGGCGGCAATCCCAATGCACTCAACTACAGTCCACGCTCCACGGGCTCTGCCTCCATATCGAGCAATGGCAGCTTGCATAAGCGTCGCTATGCCTTGGCCCTGGCCTCCGACAGCAGTCCCAGTCGCCTGGAGTTTCCCAAGCGGGCGCGTGGCCAACTggcggccacgcccacggcCACAACgatagccacgcccacgccgctgctgcgctgcagCTACTGCCCCAAGGCAACAGAGTTCAGCAGTCTCGAGCAGCTCAATGCGCATCTCCAGAGCACtcacgagcagcagcaacagcagcagcagcagcagaaggagtCGGAGGGACAGACGAATGGCTTCCAATTGAGCTGTGAATATTGCACCATGAAATTTGTGAATATCGCTGCGCTCTTCCAGCACATGAGAGTCACGCACTTGGATCGCCTGAGCAGTCCCAATTCCTATTACGAGCACTTCAATCGGCTCGGCTCGCCGCAGTCAAAGATGAAGGCAGATCAGGCGTCGTCGGAGAAGCCCGAGCAGGAGCTGCCCACCGATTTGAGCAGCAACAAGCGACGTCCGCTGATCTCGCccacccagcagcagcagcagcaacagcagccggcgccaccgccgcctcctCCTGGCATCTTCTTCTGCAATCAGTGCAACGCCGGCCTGCCGGACTTTGAGAGCTTTCGCAATCATCTCAAGAGTCACATAGCCGAGGGCATGCAGCTAATCTGTCCGCACTGCGGCCTCAGTCTGCCCGAGCAGTGCGAATACGAGCGTCATGTGGTCGCCCACTTTCTGATCAGCAGCTCCGAGTTCAATTGCTGCAGCGCCAGCTGCGGCAAGTCCTATGCCAAGGCCGAGGAGCTGCATCAGCATCTGCTGGCCGAGCACGTGCAGACGATGCTGAAGTGTGTCCTGTGCTCCGAGCTCTGCGAGAATCGCATGGCCATGCAGCTGCACTTGGCCTGTGCCCACAGCCAGGAGTCGAAGCTGCTGAGATGCAGCGCCTGCCTGGAGCTGTTTCGCAACGATGCCGACTTTCATGTGCATGTCAAGACACGCCATCAGCTGGGCAATCAGGGTCTCGGGGGTAATCCACCAGCTCCTGCCAATCCGCTGCAGTGCATGTTCTGCCGCGCCGTCTGCTCCTCGGAGCTGGAGATGCATTTCCATTTGGCGGCTCATGCGCGACAATTTCGCTGTCCCAGCTGCCCGGAGACGTTCCATGTGGAGTTCCTGCTGGACCGGCATATGCAGAGCCAGCATGGCGGCATCAAGGACAAGGAGTCGCCAGTGGCGGGCAGCATGGGCAGCCTGTATGTGAATGCATTGCTGCCACCtctggctgctgccgctgcagctgctgcagcagcaaacaatgccaacaacaacaacaataacaacaacaacaatattgatTACAATGTCGCCTTCAAGGGTCTCTTTGGCGGCAACAATCCGCCAAGCAAATTCTACAACAGCCCACTGCAGGTGGACACCAAACAGAGTCCGCATCCTGCTCTGATGTACGGCCTGAGTCAACGCTACTTGATGGAAATGTACGCCGCAAAAGCGAATTCTCCGGCCAATGCCAGCGCCCCGGAGCTGCCCACGCCCCAGGCCGTGCCATCCTCTGCCGCAgcaagcggcagcaacagcagcagcaacaacagctacagctgcgGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCCGAACTCCACTCGCATCGCAAGCTCGCCCACAATCTGAAGACGGGCGTCAGTCTGCGCTGTGCCTACTGCTCGGGCAACTACAAGAGCCGTgcggagctggagcagcacaTGAAGAGCTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATCTGTGACGAGATCTTTCCATCGCCCGCCATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCCGGCAAGTGTGCCCACTGtggccagcagctggagcacGTGGCCGCCTTTCGTGCCCACCTGGGCGAGCATGGCAACGATGGCAATCTGCCCATGGCCTGCATCTGCTGCCGCCAGACACTGCACTCGGAGTTCGAGCTCAGTTTGCATGCCAAATTCCATACCAAATCGCCCAGTTGCAATAGCCTGCAGGAGCCCGTCTGTGCCCTGTGCCTGGAGCCGCTGCCGGGAGCAGGAGAAACCGCCAAGCTGTGCGACAAATGTTGCCGCAAACACAATCTGAATGGCAAGCGCAAGGAGCAAGTGCAGCCAACTGGGGCCattgctgctccagctgcagcagctggcgcCTATCTGGAGCATCGCTGCAATCTGTGCAAAATGATCTTGCCCCATGCCCAGAAGCTGCAGGAACATCTCGTCGAGCACACGTTCGCCGGCACCGAGCAACGTGGCTACAATTGCTACATCTGCTCCGCTGTCTTCACGGCGCCCGGTGGATTGCTCGCCCACATCGCAGAGCATGGCACGCGTCCCTATGATTGCAACTTGTGCCCAGAGAAATTCTACTTCCGTGCCGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGCGcccacagccagcagcaatggcagcagctgcagctgcagcagcagcaacacgtCCTCCCAAGCAGGAGGCGCACAGCTCGACGGCCAGTTCCCCTTTGACACTAAGTCCCAGCCATGTCAAGCAGGAGCTATACGAATCGGAGCCAGCAAATTCACCCAACGCTGCTGAGCTGTCCACGCAGCCGGAGGAGGAGGAATACATCGAGGTGGAGCAGATGCCGCAGGAGACGCTGCGAACTGGCGAAATGCTGAGCACCGAACgttccagcagcagcgcctAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQLQQSQPQQQQQQQSQPGSEEAGEESAKANGDAAQQTELEQELNKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLAATPTATTIATPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQQQQQQQQKESEGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQSKMKADQASSEKPEQELPTDLSSNKRRPLISPTQQQQQQQQPAPPPPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMAMQLHLACAHSQESKLLRCSACLELFRNDADFHVHVKTRHQLGNQGLGGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVAGSMGSLYVNALLPPLAAAAAAAAAANNANNNNNNNNNNIDYNVAFKGLFGGNNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPANASAPELPTPQAVPSSAAASGSNSSSNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQVQPTGAIAAPAAAAGAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLAHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRPQPAAMAAAAAAAAATRPPKQEAHSSTASSPLTLSPSHVKQELYESEPANSPNAAELSTQPEEEEYIEVEQMPQETLRTGEMLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599822;
90% Identity: iTF_00502755;
80% Identity: -