Basic Information

Insect: Drosophila stalkeri
Gene Symbol: ZNF639
Assembly: GCA_035047405.1
Location: JAWNPR010000061.1:5946740-5948895[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0054 0.39 11.3 0.3 3 23 311 332 310 332 0.91

2 10 0.00016 0.011 16.2 0.5 6 23 341 358 341 358 0.99

3 10 9.4e-06 0.00069 20.0 0.3 1 23 364 387 364 387 0.98

4 10 0.00043 0.032 14.8 1.0 1 23 399 421 399 421 0.98

5 10 0.00031 0.023 15.2 7.7 1 23 428 451 428 451 0.96

6 10 1e-05 0.00076 19.9 2.2 1 23 457 479 457 479 0.97

7 10 0.057 4.1 8.1 0.5 2 23 488 509 487 509 0.96

8 10 0.00023 0.017 15.6 5.0 2 23 515 537 514 537 0.96

9 10 2e-07 1.4e-05 25.3 0.7 2 23 544 565 543 565 0.97

10 10 0.0002 0.014 15.9 4.4 1 23 571 594 571 594 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0054	0.39	11.3	0.3	3	23	311	332	310	332	0.91
2	10	0.00016	0.011	16.2	0.5	6	23	341	358	341	358	0.99
3	10	9.4e-06	0.00069	20.0	0.3	1	23	364	387	364	387	0.98
4	10	0.00043	0.032	14.8	1.0	1	23	399	421	399	421	0.98
5	10	0.00031	0.023	15.2	7.7	1	23	428	451	428	451	0.96
6	10	1e-05	0.00076	19.9	2.2	1	23	457	479	457	479	0.97
7	10	0.057	4.1	8.1	0.5	2	23	488	509	487	509	0.96
8	10	0.00023	0.017	15.6	5.0	2	23	515	537	514	537	0.96
9	10	2e-07	1.4e-05	25.3	0.7	2	23	544	565	543	565	0.97
10	10	0.0002	0.014	15.9	4.4	1	23	571	594	571	594	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTGtgtttaaaaaacataaacgcAAACAATGCCGTCTACCTGTTCGAGACCAGCGACACCCTGGCCGAATCGTCCCTCCTGAAGATGATAGCCAAGTTTCTACAGCTCGAGATAATGCCCGATGACAACATCTCGACGAGCATCTGTCACGAGTGCTGTGAGCATTTGGAGGATTTCAACAATTTCTGGCAGTTGGTGGAGCAAAAACAAGGAACACTTAAAAAGGAGTTCCTTACCGTGGACGTCGACTGCATTGCCCTCAAGTGGACGGGCATCGATGTCGATGTCAATATCGATGAGTTCCCACTCGTTGCCGACGAGATGGACGAGAAGCCATTGGATATACATAATCTCAAACTACTTGGCAGCGTACTTGATATTAATGTGGACAGCGTCGAGTTGCCCCCACTGGCTCCTGGCCCACAGCCAGAACAGTTCCAGACCGAGCAGTTTCTACAGCTGCATGATGCAGCACCAGATACCAGCGATGGCGATGCCGATGGCAATGACGACAATGGAAACACCAACAAAGACAATCAAACAACTGAAATCGATGAGAAGCCTGCAATGCATGAGAGCAGCGGAAGTGTGCGAAATGCATCCtccgatgacgacgacgacgACGAAGTACCCCTGGTCAAGCTGCAGCACAAACTCAAGCCGAAACGCAAAGTGCAGCGCGCCATAGCTAGGCGCAACAAGCGCACGCTTACGCTGGCCCAGGAGCTGGATCAGCTGCTGGACGACAGTGGCATCGATGGCAGCAGAACGCGACGCAAAAAGGCAGCTAACAATGCACCGACCGATGTGCAAAAGAACGAACTGCAGGCGGCGCTCGAACGCAAGCCGAAGGGCTGCTCGCGTGCGCAGCTGACGCAGCGCTACGAGGAAGCAATCGCGAGCTATATGAGCGCCGATTGTGACCTGTGCGACTACAGCACCAAGTACCTGTCCCAGCTGAAGGTCCATTTCCTGGAGGCGCATCAGCGCGATGCGTATTTGAAGTGCTGCAACAAGGTATTCAATCGCGCCTCCAAGCTAATGGATCACATACGCAAACACATCAATCCCAAGCTATTCACTTGTTCCATATGCAATAAGTCGCTCAATTCACAAGATTACCTGGCCACCCACATAGAGACGGTGCACAACAAAGTGGCCCAGATTGGCAAGGTGCTGAAGTATCCATGCTCCAAGTGCGAGCGCACCTTCAGCAGCGAGCGGCGTCTGGGCAATCATCTGCTCAAGCACGAAACGGATCAATTGGAGCACAGCTGTCACATATGCCACAAGAGCTTTGCTAATGTGCATAGACTGCGACGGCATATACAATCCATACACGAGGACCTGCATCCGCATGTCTGTGATATATGCGGCAAGAAGTTCAAGTTTAAGCCCTCCTTCGAACGGCATCTGCAGGAGCATCAGGGCTTTGTGGCCCCAGCCATGGAATGCCCCATCTGCGGTGTCTGGCTGAAGAACGAGCACAGCCTGCGGCTGCATCGCTTCACCCACGACAGTACAGACACCACATGCAAGCACTGCTCCAAGACGTGCAGCTCGCGTACAGCGCTGCGCGCCCACATCAAATACGCCCACAAGCTGACCACAAATTTGCAGTGCACGTACTGCGAGAAGAGCTTCAAGCAGCAGCGCAACCTGGAGGAGCACATGGCCATCCACACTGGGTTGCAGCTCTACAATTGCCCCCATTGCCCCAAGGAGTGCCGCAGCCGCTCCAACATGTATGTGCACATCAAACAACGGCATGCGGACGAGTGGCTCAAGGCGAAGATGGCCCGCTCCCACAATCCGCAGCTGAAGCCGCAGCTGGCGTAG
Protein Sequence: MICRLCLKNINANNAVYLFETSDTLAESSLLKMIAKFLQLEIMPDDNISTSICHECCEHLEDFNNFWQLVEQKQGTLKKEFLTVDVDCIALKWTGIDVDVNIDEFPLVADEMDEKPLDIHNLKLLGSVLDINVDSVELPPLAPGPQPEQFQTEQFLQLHDAAPDTSDGDADGNDDNGNTNKDNQTTEIDEKPAMHESSGSVRNASSDDDDDDEVPLVKLQHKLKPKRKVQRAIARRNKRTLTLAQELDQLLDDSGIDGSRTRRKKAANNAPTDVQKNELQAALERKPKGCSRAQLTQRYEEAIASYMSADCDLCDYSTKYLSQLKVHFLEAHQRDAYLKCCNKVFNRASKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCSKCERTFSSERRLGNHLLKHETDQLEHSCHICHKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLQEHQGFVAPAMECPICGVWLKNEHSLRLHRFTHDSTDTTCKHCSKTCSSRTALRAHIKYAHKLTTNLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQLKPQLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00493811;
90% Identity: iTF_00476778;
80% Identity: -