Dbuz010357.1
Basic Information
- Insect
- Drosophila buzzatii
- Gene Symbol
- Znf639
- Assembly
- GCA_035045845.1
- Location
- JAWNOS010000388.1:421014-423153[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0039 0.3 11.8 0.3 3 23 311 332 310 332 0.93 2 10 0.00016 0.012 16.2 0.5 6 23 341 358 341 358 0.99 3 10 9.6e-06 0.00075 20.0 0.3 1 23 364 387 364 387 0.98 4 10 8.8e-05 0.0069 17.0 0.9 1 23 396 418 396 418 0.98 5 10 0.00032 0.025 15.2 7.7 1 23 425 448 425 448 0.96 6 10 1.1e-05 0.00083 19.9 2.2 1 23 454 476 454 476 0.97 7 10 0.058 4.6 8.1 0.5 2 23 485 506 484 506 0.96 8 10 0.00024 0.019 15.6 5.0 2 23 512 534 511 534 0.96 9 10 2e-07 1.6e-05 25.3 0.7 2 23 541 562 540 562 0.97 10 10 0.0002 0.016 15.9 4.4 1 23 568 591 568 591 0.96
Sequence Information
- Coding Sequence
- ATGATCTGTCGCTTGtgtttaaaaaacataaacgcAAACAATGCCGTCTACTTGTTCGAGACCAGCGACACCCTGGCAGAATCCTCCCTCCTGAAGATGATAGCCAAGTTTCTGCAGCTCGAGATAATGCCCGATGACAACTTATCGACGAGCATCTGTCACGAGTGCTGTGAGCATTTGGAGGATTTCAACAATTTCTGGCAGCTGGTGGAGCAAAAGCAAGGAACACTTAAAAAGGAGTTCCTTACCGTGGATGTCGACTGCATTGCTCTCAAGTGGACAGGcatcgatgtcgatgtcaATATCGATGAGTTCCCACTCGTTGCCGACGAGATGGACGAGAAGCCATTGGATATACATAATCTCAAACTGCTTGGCAGCGTACTTGATATTAATGTGGACAGTGTCGAGTTGCCCCCACTGGCGCCTGGCCCACATCCAGAACAGTTCCAGACCGAGCAGTTTCTACAGATGCATGATGCACAACCAGATGCCAGCGATGGTGATGCCGATAGCAATGACGACAATGGAAACTCCAAAAAGAACAATCTAACAAATGAAACCGATGAGAAGCCTGCATTGCATGAGAGCAACGGAAATGTGCGAAATGCATCTTccgatgacgacgatgacgACGAAGTGCCCCTGGTCAAGCTGCAGCACAAACTCAAGCCGAAACGCAAAGCACAGCGCGCCATAGCGAGGCGCAACAAGCGCACGCTTACGCTGGCCCAGGAGCTGGATCAGCTGCTGGATGACAGCGGCATCGATGGCAGTAGAACGCGACGCAAGAAGGCAGCTAACAATGCACCGTCCGATGTGCAAAAGAACGAACTGCTGGCGGCGCTGGAACGCAAGCCCAAGGGCTGCTCGCGTGCGCAGCTAACGCAGCGGTACGAGGAGGCGATCGCGAGCTATATGAGCGCCGACTGCGACCTGTGCGACTACAGCACCAAGTACCTGTCCCAGCTGAAGGTCCATTTCCAGGAGGCGCATAAGCGCGATGCGTATTTGAAGTGCTGCAACAAGGTCTTCAATCGCGCCTCCAAGCTAATGGAGCACATACGCAAACACATCAATCCCAAGCTATTCACCTGTTCCATATGCAATAAGTCGCTCAACTCACAAGATTACCTGGCCACCCACATAGAGACGGTGCACAACAAAGTGGCCCAGGTGCTGAAATATCCGTGCTCCAAGTGCGAGCGGACCTTCAGCAGCGAGCGGCGTCTGGCCAATCATCTGCTCAAGCACGACAAGGATCAGTTGGAGCACAGCTGTCACATATGTCACAAGAGCTTTGCCAATGTGCATAGACTGCGACGGCACATACAATCCATACACGAGGACCTGCATCCGCACGTTTGTGATATATGCGGCAAGAAGTTCAAGTTTAAGCCCTCCTTCGAGCGGCATCTGCAGGAGCATCAGGGCTTTGTGGCCCCGGCCATGGAATGCCCCATCTGCGGTGTCTGGTTGAAAAACGAGCACAGCCTGCGGTTGCATCGCTTCACCCACGATAGCACCGACACCACGTGCAAGCACTGTTCCAAGACGTGCAGCTCGCGTACAGCGCTGCGCGCCCATATCAAATACGCCCACAAGCTGACCACAAATCTACAGTGCACGTACTGCGAGAAGAGCTTCAAACAGCAGCGCAACCTGGAGGAGCACATGGCCATTCACACTGGGCTGCAGCTCTACAATTGTCCCCATTGCCCCAAGGAGTGCCGCAGCCGCTCCAACATGTATGTGCACATCAAGCAACGGCATGCGGACGAGTGGCTCAAGGCGAAGATGGCCCGCTCCCACGACCCGCAGCTGAAGCCGCAGCTGGTGTAG
- Protein Sequence
- MICRLCLKNINANNAVYLFETSDTLAESSLLKMIAKFLQLEIMPDDNLSTSICHECCEHLEDFNNFWQLVEQKQGTLKKEFLTVDVDCIALKWTGIDVDVNIDEFPLVADEMDEKPLDIHNLKLLGSVLDINVDSVELPPLAPGPHPEQFQTEQFLQMHDAQPDASDGDADSNDDNGNSKKNNLTNETDEKPALHESNGNVRNASSDDDDDDEVPLVKLQHKLKPKRKAQRAIARRNKRTLTLAQELDQLLDDSGIDGSRTRRKKAANNAPSDVQKNELLAALERKPKGCSRAQLTQRYEEAIASYMSADCDLCDYSTKYLSQLKVHFQEAHKRDAYLKCCNKVFNRASKLMEHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQVLKYPCSKCERTFSSERRLANHLLKHDKDQLEHSCHICHKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLQEHQGFVAPAMECPICGVWLKNEHSLRLHRFTHDSTDTTCKHCSKTCSSRTALRAHIKYAHKLTTNLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHDPQLKPQLV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00599742; iTF_00549737; iTF_00473218; iTF_00551762;
- 90% Identity
- iTF_00476778;
- 80% Identity
- -