Basic Information

Insect: Drosophila sproati
Gene Symbol: -
Assembly: GCA_018904355.1
Location: JAEIFY010000119.1:9550537-9555633[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.12 8 6.9 0.0 1 13 347 359 347 367 0.81

2 8 7.4e-05 0.005 17.0 2.1 1 23 715 738 715 738 0.96

3 8 0.00075 0.05 13.8 3.4 1 23 767 789 767 789 0.97

4 8 9.4e-05 0.0063 16.7 6.5 1 23 795 817 795 817 0.97

5 8 3.3e-05 0.0022 18.1 0.9 1 23 823 845 823 845 0.98

6 8 0.00053 0.036 14.3 1.4 1 23 851 873 851 873 0.98

7 8 0.0098 0.66 10.3 0.0 2 23 880 901 879 901 0.96

8 8 0.015 1 9.7 0.1 3 21 909 927 907 928 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.12	8	6.9	0.0	1	13	347	359	347	367	0.81
2	8	7.4e-05	0.005	17.0	2.1	1	23	715	738	715	738	0.96
3	8	0.00075	0.05	13.8	3.4	1	23	767	789	767	789	0.97
4	8	9.4e-05	0.0063	16.7	6.5	1	23	795	817	795	817	0.97
5	8	3.3e-05	0.0022	18.1	0.9	1	23	823	845	823	845	0.98
6	8	0.00053	0.036	14.3	1.4	1	23	851	873	851	873	0.98
7	8	0.0098	0.66	10.3	0.0	2	23	880	901	879	901	0.96
8	8	0.015	1	9.7	0.1	3	21	909	927	907	928	0.91

Sequence Information

Coding Sequence: ATGACGCCAGCAGCTGTTGAGGATGGGCGTGAAAAATGCGGCAGCGTCTACACTTGGAACTGTGCTGGCGAACTCTATGGCATTGAGTGTGAGCTGTGCGAGGAGCGACCCCTTTGTGCACTCGATGAGTTTGCCGAGCATATGGAGCTGTGGCACTCCGACTGGCAACAGGCACCGGAGGATGAGCTCATGCAGGAGGTCCTCGCCGAACAGTCCAGCAGCAACTGCGAGGTCAATGAACTCAAGCAGCAGCTGGTTCAAGAGCTCAACTCGCTCGATAAACAGACACAACAGCCACAGCAGCAACAACAGCTGATGGACACATTTCAACTGAACGATCAAGTTCAGTTCAATGCGGATAGTGGCCTGCCCAGTGTGGAAACGGCAGCGAAGTTGACGACGGAGCATGTGCAGCAGCTGATTGAGCTGTATCGATCGCATCCGCGTCTGTGGGATCAATCGCATCCAGAGTTTCGGGACGTGGAGCAGTGTCGACACTCGTGGCGCCAGATAACGGATGCGTGGAGTGCCCACTGTGGACGTGGCTTCAGTGTGACCGATGTGCGCATCCGGATCTCAACGCTGTGCCAGCGATTCCTCAAGCAGCGTGAACGCATCGATGCCGAGGGTGATCTCGATGAGGGCGCCAAATTTGTCCATTACGATCAGTTGCGCTTCCTCTGCGAGCAGCAGGCGCTGCTGAAGCGCCAGGAGCACTTTGCCCGCGAGAATCGCAAACTGCTCGAGATCTATGAGCATTATCCAATACTCTGGCACAATGCCCACAAGAGATTGCGCTGCGCCGCAACGGTGAAGAGGCGCCACGAGGCACATCGTGGCCTCCAGCTGGCGTTGCGTATGTGCGGCATCAATCTGTCCGGCTTGGCGATACAGCGGCGACTCCAGTCGCTGAGGAAACGTTATCGCCTGGAGAAGATACGCTATCTGCACAGTGTCGTCGAAGGCAAACAATCGGAATTCGTGTCCATCTTTGAGCATTATGCCGAAATGGAGTTCCTGCACAAGCACATCGATCCCTATGTCTGTGCTGGCTGCGGCAAGATCTTTGAGAATCTGATCGGTCATCAGGCGCACGTGCAGGATAGCTGCGAGGAGCAGTCACTGGCTGCCGCCGACTGCAAACAGTTGACCGAATCAGAAGCGACGCTGGGCGAGCTTATGGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCTGCCGGAGAAGAACCCGAGCAGCTGCAGGTAGTGGAGCAAGTGGAACAGCAGCAGGAGCAGCTGGTGGCAGCAGCAACTACAACTGAGCTAGCCACGCCACTGCTACATAGTCTCGCAGAACAGGAGGATGCGCAGCAGGCGGAGATTGAGCAATATCCTGATAAGGAGGATCCGCACGGGAAAGAGTCTTTCTCCGAGGATAGCCTGTCGACGGGTGGACAGCTACGGATGCGCCTCAGCCTGGAGCTGACCAATAAACTGATTGAGCTCTATCAATCGCATCCAAATCTCTGGGATCCCAATCATCTGGACTATCATGCGAGGAAACAGCGACGCCAGGCCTGGCACAGCATTGCCGCCCAGCTGAACACATTCGCCGGTTGTCCGGATCGCTTCAGCTGGCAGATGTTGCATCGCAAGCTCACCGATTATGTCAAGTACTATCGACGCGAACGCCAGCGGGAGGAACTGGCGGTTGGAGGTGGTGGTGAAGGCACACGTTGGGGCTTCTATGAGGCGTTCAGCTTTATGGACGATGTGGTGCCCATAAATCGTGTGCTGCAGAAATCGTTGCAGCAGCGCGACAGCAATCTGAAGATCATCCAGGTGTATCAGAGCTACGAGCAGCTGTGGTGCACCACACATCCGGATTATACGAAACGTAAGCAGCGCTTGCGTCACCTGGAATCGCTGTGCACCCGCCTGCAGGAGGAGTGCAACCTGCAGATAACCGTTGAGCGTTTGAAGAGTCGTCTGATCGAGTTTCGCTGCCAGTATCGTCAGTGCAAGGAGGCACGCCAGGCGGCGCTGCAGCGCAACAATGCCAACTGGCAGCCGACCTATGAGTATTATGCGGCGTTGCAGTTTCTCGAACTACACGTGTCGCCATTCAACTGCGAACGGTGCACGGCGAGCTTTAAGCGGCGCAGCGATTATCTGCGGCATCAGCGCAACGTTCACTTGGACCAGCAGCTGAATGAGATGCAGCCGTTGCAACGACGCCGTCGCATGCGGCGTGGCACGAATGCGACAAATCCGCTGGAGCACATCTGTCACATTTGCGCAATGAAATTCTCGTTGCGCACCAGCCTCCAGGCGCATCTGCGACGCCATTTGGGTCAGCGGACACACTGTTGCACCGACTGCCCCAAGAAGTTCTTCAATTCGACATCGTTGCGGGTGCATCAGCGCAGCCATACCAAAGAGTTGCCGTATGTGTGCGAGCATTGTGCCCGGGGCTTTGTCAACGCCAGCAAACTGAATCAGCATGTTAAGCGGCATACGGAGAAACGGGATTATCCGTGCACGCGCTGCGACAAGGCGTTCTACACGGCCCACGAGCGAGATCGCCACTTGCGCGCCCATCTCAACATTAGGGACAAGGTCTGTCCGTATTGCAGTCGGGCCTTTGTCGTTGGCAGCGCCTACTATGCCCATCTTAATTTGCATCGGGGCGAGAAGCGTTATGGTTGTGCTGCATGTGGCAAGCGATTTGCTCAATATGCGGGTCTCTATAAGCATCGCAAGCGGTGCACAATCGCCCAGCTGCAGGAGAAGTGA
Protein Sequence: MTPAAVEDGREKCGSVYTWNCAGELYGIECELCEERPLCALDEFAEHMELWHSDWQQAPEDELMQEVLAEQSSSNCEVNELKQQLVQELNSLDKQTQQPQQQQQLMDTFQLNDQVQFNADSGLPSVETAAKLTTEHVQQLIELYRSHPRLWDQSHPEFRDVEQCRHSWRQITDAWSAHCGRGFSVTDVRIRISTLCQRFLKQRERIDAEGDLDEGAKFVHYDQLRFLCEQQALLKRQEHFARENRKLLEIYEHYPILWHNAHKRLRCAATVKRRHEAHRGLQLALRMCGINLSGLAIQRRLQSLRKRYRLEKIRYLHSVVEGKQSEFVSIFEHYAEMEFLHKHIDPYVCAGCGKIFENLIGHQAHVQDSCEEQSLAAADCKQLTESEATLGELMVXXXXXXXXXXXXXXXXXXXXXXSAGEEPEQLQVVEQVEQQQEQLVAAATTTELATPLLHSLAEQEDAQQAEIEQYPDKEDPHGKESFSEDSLSTGGQLRMRLSLELTNKLIELYQSHPNLWDPNHLDYHARKQRRQAWHSIAAQLNTFAGCPDRFSWQMLHRKLTDYVKYYRRERQREELAVGGGGEGTRWGFYEAFSFMDDVVPINRVLQKSLQQRDSNLKIIQVYQSYEQLWCTTHPDYTKRKQRLRHLESLCTRLQEECNLQITVERLKSRLIEFRCQYRQCKEARQAALQRNNANWQPTYEYYAALQFLELHVSPFNCERCTASFKRRSDYLRHQRNVHLDQQLNEMQPLQRRRRMRRGTNATNPLEHICHICAMKFSLRTSLQAHLRRHLGQRTHCCTDCPKKFFNSTSLRVHQRSHTKELPYVCEHCARGFVNASKLNQHVKRHTEKRDYPCTRCDKAFYTAHERDRHLRAHLNIRDKVCPYCSRAFVVGSAYYAHLNLHRGEKRYGCAACGKRFAQYAGLYKHRKRCTIAQLQEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01322149;
90% Identity: iTF_00499824;
80% Identity: -