Basic Information

Insect: Drosophila sproati
Gene Symbol: zfh1
Assembly: GCA_018904355.1
Location: JAEIFY010000017.1:896905-903785[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.1e-05 0.0014 18.7 1.0 1 23 151 173 151 173 0.97

2 14 0.00015 0.01 16.0 0.7 1 23 179 201 179 201 0.95

3 14 6.9e-05 0.0046 17.1 0.1 1 23 283 305 283 305 0.98

4 14 0.00024 0.016 15.4 0.9 1 23 311 333 311 333 0.98

5 14 0.54 37 4.8 4.3 1 23 371 393 371 393 0.87

6 14 0.0031 0.21 11.9 0.4 1 23 399 422 399 422 0.98

7 14 0.02 1.4 9.3 0.4 3 19 431 447 430 448 0.95

8 14 0.00012 0.0081 16.3 5.6 1 23 457 479 457 479 0.97

9 14 0.031 2.1 8.7 1.2 2 23 485 506 484 506 0.96

10 14 7e-06 0.00047 20.2 1.0 1 23 515 537 515 537 0.98

11 14 0.0008 0.054 13.8 0.1 3 23 545 565 543 565 0.97

12 14 4.3e-05 0.0029 17.8 0.5 1 23 571 593 571 594 0.95

13 14 0.036 2.4 8.5 0.4 1 23 604 626 604 626 0.97

14 14 0.00013 0.0085 16.3 0.5 1 23 1111 1133 1111 1133 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.1e-05	0.0014	18.7	1.0	1	23	151	173	151	173	0.97
2	14	0.00015	0.01	16.0	0.7	1	23	179	201	179	201	0.95
3	14	6.9e-05	0.0046	17.1	0.1	1	23	283	305	283	305	0.98
4	14	0.00024	0.016	15.4	0.9	1	23	311	333	311	333	0.98
5	14	0.54	37	4.8	4.3	1	23	371	393	371	393	0.87
6	14	0.0031	0.21	11.9	0.4	1	23	399	422	399	422	0.98
7	14	0.02	1.4	9.3	0.4	3	19	431	447	430	448	0.95
8	14	0.00012	0.0081	16.3	5.6	1	23	457	479	457	479	0.97
9	14	0.031	2.1	8.7	1.2	2	23	485	506	484	506	0.96
10	14	7e-06	0.00047	20.2	1.0	1	23	515	537	515	537	0.98
11	14	0.0008	0.054	13.8	0.1	3	23	545	565	543	565	0.97
12	14	4.3e-05	0.0029	17.8	0.5	1	23	571	593	571	594	0.95
13	14	0.036	2.4	8.5	0.4	1	23	604	626	604	626	0.97
14	14	0.00013	0.0085	16.3	0.5	1	23	1111	1133	1111	1133	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGAACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGACGACAGCGAATCAGAGATGACAGCAGCATATTTGGTCAACGCTGACGCCAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGACGGCCAACTGAGCGAAATCATCGCCGCCAATGAGGCAAATGGCGGCAGCAGCACAGTGCTAATCACGGAGAGCGATGGAAATACCGGTGTCGAGTACGCCGAGTCCTTTGAAGATGATGCCCAAGTCGTCACCGAGGAGATCATTACGGATGATTGGGTCCAGCATCAGGGTGCAGAGCGAGTGGAAATTGCCGCTGAGCAAATCGCTGGCAACGGCAGCTCCCAGGAGTTGTTGGACATGCAGCAGAATGAGTATATGGCGATGCGTCCCTATCCCTGTGACTTTTGCAGTCGACGGTTTCGGAAGAAGGCCAGCCTCAACAATCATATGCTGGCGCATCAGAATGATCGTCCCCATCCATGCAAGCTGTGCGGGGCGCGTTTCTCGCGTCGCGCGGAGCTCATAAGTCATTTCAAGGCGCATGCGGAGGCCCAGCTCAAGGAGGAGAGTTCGCAATATATTGTGATTGCCTCTGATAAACCGGAGACGGAGACGGAGTTGCCTCAATACATGCATTGCGAGACGAATTGCAATCAATCACTTGCCACCAACAACAACCAACTCCAATCAACATCCAACAATGATGTTGCAACTGCTGCTGCTGATGGAACACAGGGGCAGGGGCAGGCAACGCTGCGTTTTCCCGTGCTCGACGAGAGCAAACCCTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAACTACAGTCTACAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAACTCGGAATATGATCCGGCATCGGCGGGCGAGGAGGATACGGCGAGCGAATCGGAAGCAGAACAGCTTTACGGTAATTTCTACTGCGATGCGACGCATTGTTGCCACACGTGCGGCAAATCATTTCTCAGCGTACTCAAACTGCTCGCCCATACCGAAATCCACAAACGTTTCCCGCCATTCAAATGTGTCCTGTGCGGTGTCAGTTTCTACGAGGAGCAGGCCATAAAGCGGCACCTGAATACGCGGCATCCGCATGAGCTGAAGCCGAATTCGTGTGTGTTGTGTGGCAAGGAGTGTCGAGATCGGAAGGCGCTGATCAAACATGCTTGGGATCATTCACGGGAGAAGTGCCACTCGTGCTCCAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAACGGCACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCAGATGGACGCACCTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCCGGCAAACTGTTTCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCGCGCAGCTCGCAACAGATTCATGTGCGCATCCATACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGCGGCACTCTCCGCAAACACGAACGCATCCACACGGGCGAGAAGCCCTATGCCTGCTCCGTCTGTCCGCGTGCCTTCAATCAGCGTGTCGTGTTGCGGGAACACATCCGGTCGCATCATTCCGGTCTGGATGCGGCACGTGGCACGTATCATTGCACGGTCTGCTCCGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTACTGGTCCACGTAAATATAAACGTCGCCGGAAACTGCAGCCGCACGAGATTGCGCACATGCGCGCAGAGCACAAGGCTGGCGGTGGCGAAGGCGAGGAGGAGGATTATGGCAGCGACGTGGACTACTGCGATCTGGATGTGGAGAATGTGGATGAACTGCTGCAGGAGGCAGCCGCAGAGCCACCACCACCAGCCACCAAAAAAGCGAAACGCAAACGCAAAGCGCCAAATAAAACCGGCGATGAGCAAAGATTGTGGGATGAGAAATTCCTGCAGCAGGCCAGCAATGGGAACAGCGATGAGGCCTACAAGAGTTTCTTTCAAATGGACTCGCTGGTCGTGATCAATGATCAAACGTTGCAGCCCGTTGATGCTGGTGTTGCCACGACCAAGTTACAGCAGGCGGAGATTAAGGAGCAAAAACTCAAAACAGGCAATCGCAGCAGCAAAAGAAGGGCTGGCAAATCTGGGGGAGGAGCAGCAGGAGGAACAGCAGGAGTAGTAGAAGCTGTTGCTGCTCCACGTCCCCGCATGATACATACAGCCAAGTCGCAGCAGACAACGTCACGGAAATCCCGCACAAGGAGAGGAGCAAGCCTCATCAAATCGCGCATTGTGGATGACTACGAGATCATCTCACCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGTTGCACATCAAACAGGAGCAGGAACATCAACAGCACCATCAGCAACAGCAACAGCAACACCAACGAATCCAACTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAATCCGAGTATTGTCCAAGATCTCGAGGAGATATTGCGTAGTCCCCCTAAGCATGAGCGAAACGATCGACGGCTGCGCTTCATCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGCGAGGAGGAGGAACAGCATCTTATCAAGATCGAGCCAACGTCACCGGATCTACGCGAAATGGTTGAGAGCCAGCAGCCAGCCACACTGCCCACATCCTCCTCCGCCGCCTGCTCAACGGCGGCACGCACTTCCCGCCACCTGCGACAGCTGACTGCCAATGGTTCCACTTCCATTTCCACTGCCACTTCCAGTTCCAGTGCCGCTGCCAGCACGCGAGCCGCTGCCAAGCGCAATGCCAGCAAGCAGCTTCCCAAGAAATCCACTTCCAATAGCAGCAAAGCCAACTCATCATCGTCTTATCTCAGCTATGGTGTCGACTCCTATAATGTGGGCGTGGCAACCAGTGCCAATGGCTCCTCGGATGTCAGTTCCGGTTTCTTTTCCATTTCCGAGGTCGTCTCGGCAGCGGATGCTGCCGATGCAGCTGCGAAGGCGGCGGCGGCAGCAGCCAGCAAAACGGAGCGAAGAACGCGCTGCTTTGAGTGCGAAATGTGCTCGTCCGTTTTTCCAGATCGCTCTCAGCTGCTGGAACACATGCACATACACATCTAG
Protein Sequence: MNNPNYGGIQWIQQESSAVDDSESEMTAAYLVNADANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLITESDGNTGVEYAESFEDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHPCKLCGARFSRRAELISHFKAHAEAQLKEESSQYIVIASDKPETETELPQYMHCETNCNQSLATNNNQLQSTSNNDVATAAADGTQGQGQATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGNFYCDATHCCHTCGKSFLSVLKLLAHTEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGEGEEEDYGSDVDYCDLDVENVDELLQEAAAEPPPPATKKAKRKRKAPNKTGDEQRLWDEKFLQQASNGNSDEAYKSFFQMDSLVVINDQTLQPVDAGVATTKLQQAEIKEQKLKTGNRSSKRRAGKSGGGAAGGTAGVVEAVAAPRPRMIHTAKSQQTTSRKSRTRRGASLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHQQQQQQHQRIQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFISESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPATLPTSSSAACSTAARTSRHLRQLTANGSTSISTATSSSSAAASTRAAAKRNASKQLPKKSTSNSSKANSSSSYLSYGVDSYNVGVATSANGSSDVSSGFFSISEVVSAADAADAAAKAAAAAASKTERRTRCFECEMCSSVFPDRSQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: -
80% Identity: -