Dspr002309.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila sproati
Gene Symbol
tfap2e
Assembly
GCA_018904355.1
Location
JAEIFY010000038.1:9021482-9042010[-]

Transcription Factor Domain

TF Family
AP-2
Domain
TF_AP-2 domain
PFAM
PF03299
TF Group
Basic Domians group
Description
Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 5.4e-82 8.1e-78 260.6 0.1 1 196 315 508 315 509 0.98

Sequence Information

Coding Sequence
ATGACTTATAGTTGCCTTATTCAGTGCCAAAAAAATAATCTATCTACTGTGCATTTGTACCTGTTATGCATTTTAAGTGAACGAAGCGTTCGAGTTAGTGACAGTGAAATCCTTACCGCCCAACGATCGAAGAATTGCTACTTAATCAACGCACTCTATGTAATCGATACTACGATCCAACAATCCAACAATCCAACGCCAATAAAAATGCATATCTTACACCGGACCAATGACCATCAATTTGAGGATCAAAAATTTATGATGGAACGCCTTAGTGGCCATGGTAGCTTGGGTCTTTCTAGTAGTAGCCCGGCTTATACAACACATTCGGGAGGCCACTCGGGCAGGGGTGGCCCAACCTCCGGACACAGTGGACACAGCGGCACCCATGGGTCGACGGCTACCATGCATCATCAATCACTGCAGTCTGATTTTCAGCCTCCATACTTTCCACCACCATTTCACCACTCAGCTCAAAGCCCTCCACAGCAACAGATTTCTGGTTATTTTCAGAACCATGGTCCGCTCGAATACTTGGGAACGGATCCCTACGGCCAACCGTTATCTTCACTGCACCATGCCCCTCTTCATCACTACAATCAGTTGGCAGGCCTCAGATCCACGCAGGATCAACTGGGCATTCATAGAACTCATAGGGACGATTTGCAAGGCCATGTTACTCAACTATCCCATGGGTTTCCATACACGGAAAGAAGAAGTGATTACGGTAGTGCAATATCTGCAGGAGCAGCACACGGCACCAGACTTGGACATGAACATGAATCTCTAGCATTGCATCAAGCGTTGCAGAATGCTGTTGATGACGTCCAAGCTCCTGCTTTGGATGATAATGTGGCTTTTATGTCAGATTTACCTCTGATAAAAAGCATGAAAAGTGGGAAGGACGCTGGAAGCATAGGTTCAGGATCGCCAAGTGAAGTATTTTGTGCAGTCCCTGGTAGACTCAGTCTTTTATCAAGTACTTCAAAGTATAAGGTTACAATTGCGGAAGTCCAGCGTAGATTGTCGCCGCCCGAGTGCTTGAATGCATCTTTACTGGGTGGTGTTCTAAGAAGGGCAAAGAGCAAAAATGGAGGCCGGCTACTAAGAGAAAAGCTCGAGAAGATCGGACTAAACTTACCAGCCGGGCGGCGAAAAGCTGCAAACGTAACACTGCTAACATCTTTAGTCGAGGGTGAAGCAACGCACTTGGCCAAAGATTTTCATTTTGTTTGCGAAACTGAGTTTCCAGCTAGGCAACTGGCAGAATATATTGTGCGCCATCAAACGGAACCACAGGATTCGTATCGGCGGAAAGAGATTATACTTCACTCTCAACAGATTACAAAAGAGCTGATGCAAATTCTTAGTCAAGATCGAACCACGCATTTCGGAACAAGGTCACAGCATTTATTAGAGCCTTCAATGCAGCGGCACTTAACTCACTTTTCGTTGATAACGCATGGATTCGGCTCACCTGCAATAATAGCTGTGCTCCATGCTTTTCAGACGTTTCTTAACGAATCACTAAATTATTTGGAAAAATTGTACCCTTCTAATGGAGGCGGAATGGTATCATCATCTCTGGATAAAAATAAACTTGACAACGATAAAAAATGA
Protein Sequence
MTYSCLIQCQKNNLSTVHLYLLCILSERSVRVSDSEILTAQRSKNCYLINALYVIDTTIQQSNNPTPIKMHILHRTNDHQFEDQKFMMERLSGHGSLGLSSSSPAYTTHSGGHSGRGGPTSGHSGHSGTHGSTATMHHQSLQSDFQPPYFPPPFHHSAQSPPQQQISGYFQNHGPLEYLGTDPYGQPLSSLHHAPLHHYNQLAGLRSTQDQLGIHRTHRDDLQGHVTQLSHGFPYTERRSDYGSAISAGAAHGTRLGHEHESLALHQALQNAVDDVQAPALDDNVAFMSDLPLIKSMKSGKDAGSIGSGSPSEVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQDSYRRKEIILHSQQITKELMQILSQDRTTHFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIIAVLHAFQTFLNESLNYLEKLYPSNGGGMVSSSLDKNKLDNDKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00484129; iTF_00505794; iTF_00567938; iTF_00490467; iTF_00548483; iTF_00581955; iTF_01324579; iTF_00516676; iTF_00524804; iTF_00558340; iTF_00619524; iTF_00497831; iTF_00513863; iTF_00521031; iTF_00556903; iTF_00566471; iTF_00485544; iTF_00494792; iTF_00499272; iTF_00510952; iTF_00547048; iTF_01363624; iTF_00497065; iTF_00530634; iTF_00542122; iTF_00615882; iTF_01320874; iTF_00552715; iTF_00576748; iTF_00493326; iTF_00496271; iTF_00501487; iTF_00518127; iTF_00527727; iTF_00564335; iTF_00499984; iTF_00562864; iTF_00597040; iTF_00476305; iTF_00521841; iTF_00532049; iTF_00540049; iTF_00616593; iTF_00519603; iTF_00549235; iTF_00551987; iTF_00512404; iTF_00534996; iTF_00582644; iTF_00595636; iTF_01322325; iTF_00481910; iTF_00498550; iTF_00513142; iTF_00526262; iTF_00251031; iTF_00609560; iTF_00537913; iTF_01320153; iTF_00534267; iTF_00559899; iTF_00502204; iTF_00576028; iTF_00586364; iTF_00509501; iTF_00550623; iTF_00573727; iTF_00543424; iTF_00570080; iTF_01325344; iTF_00615270; iTF_00477032; iTF_00487691; iTF_00475631; iTF_00565776; iTF_00481238; iTF_00579671; iTF_00538648; iTF_00545657; iTF_00549948; iTF_00614591; iTF_00503680; iTF_00916870; iTF_00889799; iTF_01194962; iTF_01318706; iTF_00594932; iTF_00594230; iTF_00914171; iTF_00424330; iTF_00627905; iTF_01054914; iTF_00160355; iTF_00303491; iTF_00507300; iTF_00337190; iTF_00580358; iTF_00192488; iTF_00553448; iTF_00570792; iTF_00191051; iTF_00454219; iTF_01518571; iTF_00472047; iTF_00590639; iTF_00526992; iTF_00587824; iTF_00426801; iTF_01195697; iTF_00193235; iTF_00480564; iTF_00234487; iTF_00362935; iTF_01002455; iTF_01223895; iTF_00563578; iTF_00602266; iTF_00748666; iTF_00746395; iTF_00591388; iTF_00593533; iTF_00233598; iTF_01116133; iTF_00118375; iTF_00812393; iTF_00876714; iTF_01049322; iTF_01381772; iTF_01382594; iTF_00060783; iTF_00061608; iTF_01256088; iTF_01555120;
90% Identity
iTF_00484129; iTF_00505794; iTF_00567938; iTF_00490467; iTF_00548483; iTF_00581955; iTF_01324579; iTF_00516676; iTF_00524804; iTF_00558340; iTF_00619524; iTF_00497831; iTF_00521031; iTF_00556903; iTF_00566471; iTF_00485544; iTF_00494792; iTF_00499272; iTF_00510952; iTF_00547048; iTF_00497065; iTF_00530634; iTF_00542122; iTF_00615882; iTF_01320874; iTF_00552715; iTF_00576748; iTF_00493326; iTF_00496271; iTF_00501487; iTF_00518127; iTF_00527727; iTF_00564335; iTF_00499984; iTF_00562864; iTF_00597040; iTF_00476305; iTF_00521841; iTF_00532049; iTF_00616593; iTF_00549235; iTF_00551987; iTF_00512404; iTF_00534996; iTF_00582644; iTF_00595636; iTF_01322325; iTF_00481910; iTF_00498550; iTF_00513142; iTF_00526262; iTF_00609560; iTF_01320153; iTF_00534267; iTF_00559899; iTF_00502204; iTF_00576028; iTF_00509501; iTF_00573727; iTF_00543424; iTF_00570080; iTF_01325344; iTF_00601441; iTF_00554755; iTF_00618023; iTF_00500717; iTF_00577453; iTF_00603757; iTF_00502929; iTF_00599990; iTF_00483358; iTF_00523358; iTF_00611742; iTF_00555520; iTF_00507300; iTF_00602266; iTF_00591388; iTF_00337190; iTF_00580358; iTF_01569926; iTF_00513863; iTF_00889799; iTF_01557959; iTF_00570792; iTF_01363624; iTF_00251031; iTF_00901163; iTF_00522638; iTF_00060783; iTF_00061608; iTF_01194962; iTF_00472047; iTF_00553448; iTF_00590639; iTF_00526992; iTF_00587824; iTF_00519603; iTF_01553651; iTF_01552135; iTF_00480564; iTF_01550676; iTF_01552852; iTF_00594230; iTF_00578967; iTF_00563578; iTF_00586364; iTF_01556508; iTF_00593533; iTF_00550623; iTF_00338823; iTF_00336402; iTF_00335541; iTF_00338007; iTF_00574492; iTF_01548541; iTF_01549260;
80% Identity
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