Basic Information

Gene Symbol
-
Assembly
GCA_035047465.1
Location
JAWNPQ010000131.1:2413559-2414284[-]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 6 5.3e+03 -2.4 0.4 58 66 12 20 6 24 0.60
2 2 2.5e-14 2.2e-11 43.6 12.9 6 70 139 203 135 203 0.96

Sequence Information

Coding Sequence
ATGTCCAAAGCACCCACCGATGTGCAGTACCTGCGCTGCCTCAAGTGCCTGAAGATAATTAAATGCTCGCGCTACGACACCAGCTGCCTGGTGCGTCACGTGCAGAAGGATCATCCGGAGATCATTGACGAGTCCAACGAGAAGGTGCTCAATCTGCACAAGCTGGCCGCCGAGCACGGCATCAGCGAGGAGCGGCTGTCACAGATCAGCAAGATGACGGGCATGTCCGAGGCGGAAATGGCCGACGAGGCCGATCGCTATCTGCAGCGCAAGCAGTTGGGCGACGGTCGCCCGCCAGATGGGAAAAACCAGTGCCAATCGGATAAACCGCCCAGGCGGACGGACTCCAAGGAACTGAACAGACGCCAATTCTATCGGACCTCCATTGAGCGTTGGATGCCCATCGATGGCTGCATTTACTGTCCCTCCTGCGGCTGCAATCGCCGGCCCCTGATCAAGACCAGCTCCGAGTTCTACACCAGCACCGGCTGCTCGGCGGCCTGTGTGGCCAACTGCTGGCCCTTCTGCTTCCTGCCCTGCCTCAACTCGACCGACAATCGCGAATATCTGCACTGCTCCAACTGCAAGACCTTCCTGGGCATCTACGATCGCGAGCACAACTGCATACGACCCAACCGCGATTTTGTGCCCTCCTAG
Protein Sequence
MSKAPTDVQYLRCLKCLKIIKCSRYDTSCLVRHVQKDHPEIIDESNEKVLNLHKLAAEHGISEERLSQISKMTGMSEAEMADEADRYLQRKQLGDGRPPDGKNQCQSDKPPRRTDSKELNRRQFYRTSIERWMPIDGCIYCPSCGCNRRPLIKTSSEFYTSTGCSAACVANCWPFCFLPCLNSTDNREYLHCSNCKTFLGIYDREHNCIRPNRDFVPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00531361;
90% Identity
iTF_00496262; iTF_00589224;
80% Identity
-