Basic Information

Insect: Drosophila sordidula
Gene Symbol: ken1
Assembly: GCA_035047465.1
Location: JAWNPQ010000185.1:8166028-8168436[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0017 0.11 12.9 4.9 3 23 259 279 257 279 0.96

2 12 0.00068 0.044 14.2 0.4 1 23 285 310 285 310 0.93

3 12 0.015 0.98 9.9 0.2 1 23 317 342 317 342 0.92

4 12 0.00059 0.038 14.4 5.0 1 23 352 374 352 374 0.97

5 12 9.4e-06 0.00061 20.0 1.1 1 23 381 403 381 403 0.98

6 12 0.0074 0.48 10.9 0.5 1 23 409 431 409 431 0.97

7 12 0.0077 0.5 10.9 3.8 1 23 437 460 437 460 0.97

8 12 0.016 1 9.9 2.4 1 23 466 488 466 488 0.96

9 12 0.0022 0.14 12.6 2.2 2 23 495 516 494 516 0.96

10 12 0.00019 0.012 15.9 0.8 1 23 605 628 605 628 0.95

11 12 0.14 8.8 6.9 1.9 1 21 634 653 634 656 0.73

12 12 4.3e-05 0.0028 18.0 2.0 1 23 662 685 662 685 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0017	0.11	12.9	4.9	3	23	259	279	257	279	0.96
2	12	0.00068	0.044	14.2	0.4	1	23	285	310	285	310	0.93
3	12	0.015	0.98	9.9	0.2	1	23	317	342	317	342	0.92
4	12	0.00059	0.038	14.4	5.0	1	23	352	374	352	374	0.97
5	12	9.4e-06	0.00061	20.0	1.1	1	23	381	403	381	403	0.98
6	12	0.0074	0.48	10.9	0.5	1	23	409	431	409	431	0.97
7	12	0.0077	0.5	10.9	3.8	1	23	437	460	437	460	0.97
8	12	0.016	1	9.9	2.4	1	23	466	488	466	488	0.96
9	12	0.0022	0.14	12.6	2.2	2	23	495	516	494	516	0.96
10	12	0.00019	0.012	15.9	0.8	1	23	605	628	605	628	0.95
11	12	0.14	8.8	6.9	1.9	1	21	634	653	634	656	0.73
12	12	4.3e-05	0.0028	18.0	2.0	1	23	662	685	662	685	0.98

Sequence Information

Coding Sequence: ATGGACGAGGAGAGTGAATACTCCATACATTCGATTTGTCGTATTTGCTTGATTCACTTGCGCACCGCTCCGGCCTTCGACCTGTTTCTGGTCCCTGGCCTGGCCAAGAAGTTGTGCGTCTGCACCTCCCTCTCCGTGGAACAGCACGATGGATTCCCGAAGAACCTCTGCACCAATTGCTACACCCGGCTCAATGATTTGCACGGCTTCCAGAAGCTGTGCGTGGACTCGGTCCAAAAGTTTCAAGAAATGGTCGCCAGCAATTATTTCGTGCCCGTCGCGGGCGACGTGGACAATGTCGATATACTGAACGCTGCGGCGCACGACGGGGATGAGGATCGCATCAACTTTGATCCGCTGCTAAACACTAAAATAGAGATAGTGGAGACTGACGATGTTTTTAAAATGCTCGACGATGTGGACAAAGACGTGGAGGAGGTGGAAAAGGGGAAGGAGTCCTGCAGTGAAAGCGAGAACGATGTTTATAATGACAATGATGATGACAGGGATGTTGACTATGTGGCGAATAGCAGCGACTCCGAGGATGGCATGCCCCTGTCCCGCCTGCGAAGTGGCACCAAACCAACCAAAGCGAAGGCGAAGCCGAAGTCCAAAAAGAAAGCTGCCGATAAAGATGACGGAGATTCCTCTAGCTTTGAATGGAAAGAGGAAATTGACGATGAAAAGAACAAAGAGCCTCCAACCAAGAAGAAATCAAGACGCAAACGCGTTCGCATTCCACCCCCGGCGCCCCAACAAGATGATTTAATCGATTGTCACATTTGTCACAAGAAATTCAAGAGCGCAGAAGTCTACGAGGAACACATGAAGCATCACGACGATCTCTTGCCGTACCAGTGCACTGTGGAGGCCTGCAAGAAGGGCTTCACTACATCGGGTGCCCTGCGCCTGCACATGGACCACGCCCATTCAGAACTCTCTGAGGTGCATGCCTGCACTGTTGAGGGATGTGGCATGACATTCCCTCGACCCGTTCTACTCACGTTCCACTTGAAGAAGGTGCACAAGATCCACAGACCCAAGGCACGAGATCATCCCTGCACCGAGTGCGACAAGGTGTTCCGCTGTTCCACGGCGCTCAGGAAGCACATGTACAAGCACACGGGCGAGGAGAAGCCCTATCCGTGCAACATCTGCGGCAAACGGTTCCACATTAACAGCGAACTCAAAGACCATCTCCTGCGCCACGCCGGCGTTAAGAACCACGTGTGCCCTTATTGCGGCGTGGGCAAAACCACTCGCCAGGAGTGGAACAAGCACATTCTGACCCACACCAAGgagaaaatattcaaatgccaGCAGTGCGATCATTCGTCCCACAACAAGCAGGCGCTGACCAACCACGTCAAGGTGGTGCACCTGAAGATCAAGGACTACGCCTGCCAGTTCTGCGGCAAGACGTTCGGCAAGTCGTACGCCTGCAAGGTGCACGAGAGACTCCACACGCGCGAGAACTGCTGCGAGTGCAACATCTGCGGCAAGATCTTCCTTTTCGAGCGGAGTCTGACGAAGCACTTGAAGCTCCATGAGAAGCGCGAAGCAGCAAAGGCCGCGACCGCCGTTAAATCGCAGGCCGACAACGATGATCCGAACAGCCAGAATTCCAACCAGGAGGCGACTGACCAGGTGGACGTGAAGGTGGTTCCAATATACCCTCCCAAGCCGAACAATGCGTATAGAGTGGCGCGTGTGGACTTATCCGAACTGGCCGGGACCTCGGTCAATCCCATTCCATCGGTCTCTGTGGCATCTTGGTCGCCACAGGCCAACTTCACCAAGAAGGAGGGCCAGCACATTTGCCCCGGCTGCGGTCGTGGCTTCAACCACATTGGCAACATGAAGCTCCACTACAAGATCATCCACGAAAAGGTGAAGGACTTCGCCTGTCGCTTCTGTCCCAAGCGCTTCTCGAAGGCACAAATCTTGCGGCATCACGAATGGACTCACACGGGCGAGAAGCCGTACGAGTGCAAGATATGCGGCAAGCATTTCCGGCAGGAGCAGGTTATGAAGAATCATGTGCGCAGGGTGCACGAGACTCCGGCGAAGCCAGCCAAGGAACCGAAACGCCCAAAACCAGATAAAAACAGGGAAAAGCGCCCGAAGGTTGATctcaacaaaacaaagcaacccAAGATTTTCGACGAGTTCCAGGATCCGGCTGCCGAACGTGCCGCAGCTACGGCTGCACTGCTCGCCCAACAGGCCGAGGAGAACGAGGCCAAGCGAAAGGCGGAGGAGAAAACTCGCAGGATTCAGGAGGCCGCATGCGAACAGCTTCagaagctgcagcaggagcagcttATTGAGAAGTTACCCAGCGATAGCTTCCAAGTTACGAAATCGGAAACCGGCATCACCGTGGATGACCTTAAAGAAGATCCTTAA
Protein Sequence: MDEESEYSIHSICRICLIHLRTAPAFDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTRLNDLHGFQKLCVDSVQKFQEMVASNYFVPVAGDVDNVDILNAAAHDGDEDRINFDPLLNTKIEIVETDDVFKMLDDVDKDVEEVEKGKESCSESENDVYNDNDDDRDVDYVANSSDSEDGMPLSRLRSGTKPTKAKAKPKSKKKAADKDDGDSSSFEWKEEIDDEKNKEPPTKKKSRRKRVRIPPPAPQQDDLIDCHICHKKFKSAEVYEEHMKHHDDLLPYQCTVEACKKGFTTSGALRLHMDHAHSELSEVHACTVEGCGMTFPRPVLLTFHLKKVHKIHRPKARDHPCTECDKVFRCSTALRKHMYKHTGEEKPYPCNICGKRFHINSELKDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKIFKCQQCDHSSHNKQALTNHVKVVHLKIKDYACQFCGKTFGKSYACKVHERLHTRENCCECNICGKIFLFERSLTKHLKLHEKREAAKAATAVKSQADNDDPNSQNSNQEATDQVDVKVVPIYPPKPNNAYRVARVDLSELAGTSVNPIPSVSVASWSPQANFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWTHTGEKPYECKICGKHFRQEQVMKNHVRRVHETPAKPAKEPKRPKPDKNREKRPKVDLNKTKQPKIFDEFQDPAAERAAATAALLAQQAEENEAKRKAEEKTRRIQEAACEQLQKLQQEQLIEKLPSDSFQVTKSETGITVDDLKEDP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567718;
90% Identity: iTF_00589028; iTF_00496048;
80% Identity: -