Basic Information

Insect: Drosophila robusta
Gene Symbol: ken1
Assembly: GCA_004143805.1
Location: SCDV01000353.1:60350-62860[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0014 0.18 12.9 4.9 3 23 260 280 258 280 0.96

2 12 0.00056 0.071 14.2 0.4 1 23 286 311 286 311 0.93

3 12 0.013 1.6 9.9 0.2 1 23 318 343 318 343 0.92

4 12 0.0017 0.21 12.7 4.9 1 23 353 375 353 375 0.97

5 12 7.8e-06 0.00098 20.0 1.1 1 23 382 404 382 404 0.98

6 12 0.0061 0.77 10.9 0.5 1 23 410 432 410 432 0.97

7 12 0.0092 1.2 10.4 5.8 1 23 438 461 438 461 0.97

8 12 0.013 1.6 9.9 2.4 1 23 467 489 467 489 0.96

9 12 0.0018 0.23 12.6 2.2 2 23 496 517 495 517 0.96

10 12 0.00016 0.02 15.9 0.8 1 23 606 629 606 629 0.95

11 12 0.11 14 6.9 1.9 1 21 635 654 635 657 0.73

12 12 3.6e-05 0.0045 17.9 2.0 1 23 663 686 663 686 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0014	0.18	12.9	4.9	3	23	260	280	258	280	0.96
2	12	0.00056	0.071	14.2	0.4	1	23	286	311	286	311	0.93
3	12	0.013	1.6	9.9	0.2	1	23	318	343	318	343	0.92
4	12	0.0017	0.21	12.7	4.9	1	23	353	375	353	375	0.97
5	12	7.8e-06	0.00098	20.0	1.1	1	23	382	404	382	404	0.98
6	12	0.0061	0.77	10.9	0.5	1	23	410	432	410	432	0.97
7	12	0.0092	1.2	10.4	5.8	1	23	438	461	438	461	0.97
8	12	0.013	1.6	9.9	2.4	1	23	467	489	467	489	0.96
9	12	0.0018	0.23	12.6	2.2	2	23	496	517	495	517	0.96
10	12	0.00016	0.02	15.9	0.8	1	23	606	629	606	629	0.95
11	12	0.11	14	6.9	1.9	1	21	635	654	635	657	0.73
12	12	3.6e-05	0.0045	17.9	2.0	1	23	663	686	663	686	0.98

Sequence Information

Coding Sequence: ATGGACGAGGAGAGTGAATACTCCATACATTCGATATGTCGCATTTGTTTAATTCACTTGCGCACCGCTCCGGCCTTCGACCTGTTTCTGGTCCCTGGCCTTGCCAAGAAGCTCTGCGTCTGCACCTCCCTCTCCGTGGAACAGCACGATGGATTCCCGAAGAACCTCTGCACCAATTGCTACACGCGACTCAATGATTTGCACGGCTTTCAGAAGCTGTGCGTGGACTCGGTCCAAAAGTTTCAAGAAATGGTAGCCAACAATTATTTCGTGCCCGTCGCGGGCGACGTGGACAATGTCGATATACTGAACGCAGCGACGCACGACGGGGATGAGGATCGCATCAACTTTGATCCGCTACTAAACACTAAAATAGAGATAGTGGAGACTGACgatgtttttaaaatgctcGACGATGTGGACAAAGACGTGGAGGAGGTGGAAAAGCAGAAGGAGTCCTGCAGTGAAAGCGAAAACGATATTTATAATGACAATGATGATGACAGGGATGTTGACTATGTGGCGAATAGCAGCGACTCCGAGGATGGTATGCCCCTGTCCCGCCTGCGAAGTGGCACCAAACCAACCAAAGCGAAGGCGAAGCCGAAGTCGTCCAAAAAGAAAGCTGCCGATAAAGATGACGGAGATTCCTCTAGCTTTGAATGGAAAGAGGAAGTTGATGACGAAAAGAACAAAGAGCCTCCGACCAAGAAAAAATCAAGACGTAAACGCGTTCGCATTCCACCCCCTCAGCCACAACCAGATGATTTGATCGATTGTCACATTTGTCACAAGAAATTCAAGAGCGCAGAAGTCTACGAGGAACACATGAAGCATCATGACGATCTCTTGCCGTACCAGTGCACTGTGGAAGCCTGCAAGAAGGGCTTCACTACATCGGGTGCCCTGCGCCTGCACATGGACCACGCCCATTCAGAACTTTCTGAGGTGCACGCCTGCACCGTTGAGGGATGTGGCATGACATTCCCTCGGCCCGTTCTACTCACGTTCCACTTGAAGAAGGTGCACAAGATCCACAGACCCAAGGCACGAGACCATCCCTGCACCGAGTGCGAAAAGGTGTTCCGCTGTTCCACGGCGCTCAGGAAGCACATGTACAAGCACACGGGCGAGGAGAAGCCCTATCCGTGCAACATCTGCGGCAAACGCTTCCACATTAACAGTGAACTCAAAGACCATCTCCTGCGCCACGCCGGCGTCAAGAACCACGTTTGCCCTTATTGCGGCGTGGGCAAAACCACTCGCCAGGAGTGGAACAAGCACATTCTGACCCACACCAAGgagaaaattttcaaatgccaCCAGTGCGATCATTCGTCCCACAACAAGCAGGCGCTGACCAACCACGTCAAGGTGGTGCACCTGAAGATCAAGGACTACGCCTGCCAGTTCTGCGGCAAGACGTTCGGCAAGTCGTACGCCTGCAAGGTGCACGAGAGACTGCACACGCGCGAGAACTGCTGCGAGTGCAACATCTGTGGCAAGATCTTTCTTTTCGAGCGCAGTCTGACGAAGCACTTGAAGCTCCATGAGAAACGCGAAGCAGCAAAGGCCGCGACCGCTGTTAAATCGCAGGTCGACAATGATGATCCGAACAGCCAGAATTCCAACCAGGAGGCGACTGACCCTGTGGACGTGAAGGTGGTTCCAATATACCCTCCCAAGCCGAACAATGCATATAGAGTGGCGCGTGTGGACTTATCCGAACTGGCCGGGACCTCTGTCAATCCCATTCCATCGGTGTCTGTGGCATCCTGGTCGCCACAGGCCAACTTCACCAAGAAAGAGGGCCAGCACATTTGCCCCGGCTGCGGTCGTGGCTTCAACCACATTGGCAACATGAAGCTCCACTATAAGATTATCCACGAAAAGGTGAAGGACTTCGCCTGTCGCTTCTGTCCCAAGCGCTTCTCGAAGGCACAAATCTTGCGGCATCACGAGTGGACTCACACGGGCGAGAAGCCGTACGAGTGCAAGATATGCGGCAAGCATTTCCGGCAGGAGCAGGTTATGAAGAATCATGTGCGCAGAGTGCACGAGACTCCGGCGAAACCAGCCAAGGAACCGAAACGCCCAAAACCAGATAAAAACAGGGAAAAGCGCCCGAAGGTCGAtctcaacaaaacaaaacaacccAAGATTTTCGACGAGTTCCAGGATCCGGCTGCCGAACGTGCCGCAGCTACGGCTGCACTGCTCGCCCAACAGGCCGAGGAGAACGAGGCCAAGCGAAAGGCGGAGGAGAAAACTCGCAGGATTCAGGAGGCCGCATGCGAACAGCTTcagaagctgcagcaggagcagcttaTTGAGAAGTTACCCAGCGATAGCTTCCAAGTTACAAAATCGGAAACCGGCATCAGCGTGGATGACCTTAAAGAAGATGCTTAA
Protein Sequence: MDEESEYSIHSICRICLIHLRTAPAFDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTRLNDLHGFQKLCVDSVQKFQEMVANNYFVPVAGDVDNVDILNAATHDGDEDRINFDPLLNTKIEIVETDDVFKMLDDVDKDVEEVEKQKESCSESENDIYNDNDDDRDVDYVANSSDSEDGMPLSRLRSGTKPTKAKAKPKSSKKKAADKDDGDSSSFEWKEEVDDEKNKEPPTKKKSRRKRVRIPPPQPQPDDLIDCHICHKKFKSAEVYEEHMKHHDDLLPYQCTVEACKKGFTTSGALRLHMDHAHSELSEVHACTVEGCGMTFPRPVLLTFHLKKVHKIHRPKARDHPCTECEKVFRCSTALRKHMYKHTGEEKPYPCNICGKRFHINSELKDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKIFKCHQCDHSSHNKQALTNHVKVVHLKIKDYACQFCGKTFGKSYACKVHERLHTRENCCECNICGKIFLFERSLTKHLKLHEKREAAKAATAVKSQVDNDDPNSQNSNQEATDPVDVKVVPIYPPKPNNAYRVARVDLSELAGTSVNPIPSVSVASWSPQANFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWTHTGEKPYECKICGKHFRQEQVMKNHVRRVHETPAKPAKEPKRPKPDKNREKRPKVDLNKTKQPKIFDEFQDPAAERAAATAALLAQQAEENEAKRKAEEKTRRIQEAACEQLQKLQQEQLIEKLPSDSFQVTKSETGISVDDLKEDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567718;
90% Identity: iTF_00598345;
80% Identity: -