Dsor002585.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila sordidula
Gene Symbol
-
Assembly
GCA_035047465.1
Location
JAWNPQ010000090.1:836742-840397[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.6e-13 1.8e-10 40.8 0.1 4 108 25 144 22 146 0.89

Sequence Information

Coding Sequence
ATGAGCGCACGTTCACCGCACAGCGATCCAGCTTTGGCTGGGCTGCCGCAGCTAATTGAGGACTTACAGCGCTTGTGCGAGGATCAGGACAGCGCCGATGTGGTGTTCATATGTGGACGGGATGACGAGAAGATCTACGCACATCGAAGCATTCTGATGGCGCGCTGTAAGAGCTTTAAGACTGCCAAGCGTGGAGAGGTCTGCCGCATACCCATTCCCGGATGCACCGTTTCACCGGCAGCGCCAGGCACTGGCACGCCGACTGCAATACGTTTGCCGCATATTAATGCCGAGCTGTTTCGCcagtttatattatatgtctATACAGCAAAGCTTATGCTGCAGGATTACCGGGTTTTTGAAATGTTAACATTGGCCCAAGACATGGGTGTATTTGAGCTGCGCGCCGCTTGCGAGGATCATGTTATTTCCACACTATCTGTAGATAATGCTTGCACATTTTTAACCGCTGTCATGGATATTCACGAAAAAGCAGGTGCCAAGTGCGCGGCTTCTTTCATGGAACGCTGCATCATTTACATTGGCGAAAACGCCGGCGAGTGTGTTAAAACCAATTCTTTTCTCACCCTAACCAAGGAAGCCCTCATCAAAATCATTTCGTCGGACTATTTCTGTTTGGAGGAGGAAGAGGTCTGGCGTTGCGTCTTGGCCTGGGCCAAGTATCAGGCGGGGGTCACCCAACCCACAGCCCACTGGACAGAAGAGGAGCGTGCTCGCGTCTGCCAGCATCTAAGCGGCGTCATGGGCCATGTGCGCCTGCTGCTCATCGATAGCCAGGTGTTTGCCGAGGAAGTTGAGCCCACCGGCGCTGTGCCCATGGAGCTGTCACTGGAACGCTATCGCTACGCTGCCTTGCATCCCAATAAGCTGGTGGACAACGATAAGCGTCTGCAGCCACGGTTGGCTGTGAATATGTTTCCGGGCTCGCAAATCTTGCGCAACGACAAGCTGGCCCTGCAGGGCATACTCAACGGTTGGTTTGGAGTGCCCAAACAGAGCTGGCGCTTGGTCTATCGCGCCTCAACGCACGGCTTTGGCTCGACCTCCTTCCATCGCTATTGCGACGGCGTGGCGCCCTGCATGGTTATTGGCTTGGGCGCACATGGCGAGATTAGCGGCGGTTATACGGATGTCGCCTGGGCGAAGACCAGTCGCAAGGGCGGCTATTTGCATTCGGAGCGCGCCTTTCTCTTCATTTTGAATCCACCAAATGGCGAGCAGCCCACCAAATTCGATATCGTTAAGAAACCATATGCCATCTGCTATCATCCAGATTGCGGTCCCATATTTGGCGCTGGTGCCGATCTGCTCGTATCCAGCAATTGTAATGTGAACACGGACTCGTATTCGAATTTGCCGCACTCCTACGATGGACCCAATGTCGCACATCTGACGCTCTTTGGCGACTACAATTTTGCGATCAGCGATTACGAGGTTTACACTCTGGCCGCCACCCACGGCCAcagtcaaagccaaagccaaagcctgGCGAGCAATGGCCAGGCGCCGGGTGTGCCCAGCAAGGCAAAATACGATAGATACTAA
Protein Sequence
MSARSPHSDPALAGLPQLIEDLQRLCEDQDSADVVFICGRDDEKIYAHRSILMARCKSFKTAKRGEVCRIPIPGCTVSPAAPGTGTPTAIRLPHINAELFRQFILYVYTAKLMLQDYRVFEMLTLAQDMGVFELRAACEDHVISTLSVDNACTFLTAVMDIHEKAGAKCAASFMERCIIYIGENAGECVKTNSFLTLTKEALIKIISSDYFCLEEEEVWRCVLAWAKYQAGVTQPTAHWTEEERARVCQHLSGVMGHVRLLLIDSQVFAEEVEPTGAVPMELSLERYRYAALHPNKLVDNDKRLQPRLAVNMFPGSQILRNDKLALQGILNGWFGVPKQSWRLVYRASTHGFGSTSFHRYCDGVAPCMVIGLGAHGEISGGYTDVAWAKTSRKGGYLHSERAFLFILNPPNGEQPTKFDIVKKPYAICYHPDCGPIFGAGADLLVSSNCNVNTDSYSNLPHSYDGPNVAHLTLFGDYNFAISDYEVYTLAATHGHSQSQSQSLASNGQAPGVPSKAKYDRY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00832284;
90% Identity
iTF_00495970; iTF_00530373; iTF_00579393; iTF_00803715; iTF_00508454; iTF_00805303; iTF_01548966; iTF_01550379; iTF_01551838; iTF_00570504; iTF_00583073; iTF_00512835; iTF_00511398; iTF_00513574; iTF_00576456; iTF_00495241; iTF_00598985; iTF_00610025; iTF_00619977; iTF_00496746; iTF_00541867; iTF_00552427; iTF_00517100; iTF_00548940; iTF_00566924; iTF_00521517; iTF_00593229; iTF_00597517; iTF_00485966; iTF_01327278; iTF_00498991; iTF_00500432; iTF_00514288; iTF_00528176; iTF_00535440; iTF_00596048; iTF_00577169; iTF_00616306; iTF_00518548; iTF_00522324; iTF_00543860; iTF_00498262; iTF_00497527; iTF_00542552; iTF_00560408; iTF_00525275; iTF_00558843; iTF_00553148; iTF_00567644; iTF_00607196; iTF_00501917; iTF_00564766; iTF_00482367; iTF_00557312; iTF_00574176; iTF_00547465; iTF_01556939; iTF_00546764; iTF_00476737; iTF_00540481; iTF_00479589; iTF_00509925; iTF_00572709; iTF_00586790; iTF_00493767; iTF_00532488; iTF_00545355; iTF_00502636; iTF_00568366; iTF_00551696; iTF_00559601; iTF_00599700; iTF_00473173; iTF_00573432; iTF_00516377; iTF_00549659; iTF_00554491; iTF_00520028; iTF_00544605; iTF_00558030; iTF_01321305; iTF_01322764; iTF_01326529; iTF_01324254; iTF_00610765; iTF_01328005; iTF_00519273; iTF_01325033; iTF_01323504; iTF_01325778; iTF_00802965; iTF_00832284; iTF_00584526; iTF_00534690; iTF_00533925; iTF_01553352; iTF_01559146; iTF_00601931; iTF_00585324; iTF_00506989; iTF_00608557; iTF_00537619; iTF_00563284; iTF_00588948; iTF_00617012; iTF_00528922; iTF_00583802; iTF_00586075; iTF_00475327; iTF_01554815; iTF_01320577; iTF_00490890; iTF_01549675; iTF_00506227; iTF_00550998; iTF_00526689; iTF_00531063; iTF_00595351; iTF_00520738; iTF_00556614; iTF_00589646; iTF_00562577; iTF_00472466; iTF_00901618; iTF_00509208; iTF_00614298; iTF_00587512; iTF_00538337; iTF_00561146; iTF_00575706; iTF_00582362; iTF_01555515; iTF_00806077; iTF_00470982; iTF_00478837; iTF_00569085; iTF_01570344; iTF_00510656;
80% Identity
-