Basic Information

Insect: Drosophila sordidapex
Gene Symbol: RREB1
Assembly: GCA_035043295.1
Location: JAWNNA010000155.1:2896993-2903699[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.04 2.5 8.8 0.8 1 21 266 286 266 288 0.93

2 12 0.00038 0.024 15.1 0.2 1 23 298 320 298 320 0.98

3 12 0.00028 0.018 15.5 7.2 1 23 326 348 326 348 0.98

4 12 0.99 62 4.4 1.5 2 20 577 595 577 597 0.93

5 12 0.019 1.2 9.8 0.2 1 23 741 763 741 763 0.97

6 12 1.4e-05 0.00088 19.7 0.7 1 23 773 795 773 795 0.99

7 12 0.00093 0.059 13.9 2.0 1 23 801 824 801 824 0.97

8 12 0.0033 0.21 12.2 2.0 1 23 1088 1111 1088 1111 0.95

9 12 9.7e-05 0.0061 17.0 0.3 2 23 1491 1512 1490 1512 0.97

10 12 0.16 10 6.8 6.3 1 23 1518 1541 1518 1541 0.97

11 12 0.0095 0.6 10.7 0.5 3 23 1744 1764 1742 1764 0.96

12 12 0.0015 0.095 13.2 4.8 1 23 1770 1792 1770 1792 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.04	2.5	8.8	0.8	1	21	266	286	266	288	0.93
2	12	0.00038	0.024	15.1	0.2	1	23	298	320	298	320	0.98
3	12	0.00028	0.018	15.5	7.2	1	23	326	348	326	348	0.98
4	12	0.99	62	4.4	1.5	2	20	577	595	577	597	0.93
5	12	0.019	1.2	9.8	0.2	1	23	741	763	741	763	0.97
6	12	1.4e-05	0.00088	19.7	0.7	1	23	773	795	773	795	0.99
7	12	0.00093	0.059	13.9	2.0	1	23	801	824	801	824	0.97
8	12	0.0033	0.21	12.2	2.0	1	23	1088	1111	1088	1111	0.95
9	12	9.7e-05	0.0061	17.0	0.3	2	23	1491	1512	1490	1512	0.97
10	12	0.16	10	6.8	6.3	1	23	1518	1541	1518	1541	0.97
11	12	0.0095	0.6	10.7	0.5	3	23	1744	1764	1742	1764	0.96
12	12	0.0015	0.095	13.2	4.8	1	23	1770	1792	1770	1792	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaacagcagcaaccacaacagcaacaatcgcacacagcagcagcaactgcagtagcagcagcagcagcagcaacacaagaGGATGCTCGGGATTTGGGATTAATGGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAACTGCGACAgccacaccagcagcagcagcagcaacagttgccgctcTCCGAtgaggagcaacagcagcaacagcagcagcagctgttggaTTCGTCAACGCAGCGACCGCGTCACAAGCAGCGGCGcagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAATCGCAGTAGCGCCAGCAGCAATGCCGCCAACGGTGATTTATCCGAGTCTGGCTTTGTTGATGGCAGCGCCGTCAGTGGCTATCTgcttagcaacaacaacaataacaacaacaataacaatatcaacaacaatatcagtagcagtagcagcagcagcgcagtcgctcagtcagcagcagcagcagcgtcggcTGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGGGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGCCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAGgcctcgcagcagcagcagcagcagcagccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcgacgccAGCAACATGCGGGCGGAGCAGACGCAACTGGCTCGGGATCGGGATCAGCACAGTTGTTGACGACGCGTGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaatagccacaaaacgaacaacaataacaacaacaacaacaacaataataataataacaatgaggatgagcttgagctggaggATGAGCAGCTAGTATTGAGCAACAAACAGCGACGCCTCAAGGCAGccttaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCGGATGTGGATAGCGTTGAGAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATTACATTCACCGCCCCTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGCTGTGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAactggaggagcagcagcagcagcacgaggAGGATCACgaacagcagcacaagcaggaGGAACAGGAGCACGCCGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGGGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGTTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATCGGCCATACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCAAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGACCGATGCCGATATGCTAACCGAGCTGAGCGGCTATCGCTGTCCCACACCCACGGAGCACAGCTCCTCAGCTAGCTCTTCGTCACAGCTAAAGCATATGTTGCTGGCGGAGCCGACGCCGGCCGTaaaagtaacagcaacagcagcagcaacggtggcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTTGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACAtgaattgctgctgcagcagcaacaccaacagcagcagcagcaacaacagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCacgccgccgccaccagcaacggcggcagcagcagcagacaagtcaatgccaacaaatccagcagcagcagccggcgcaacagcagcaacaattgctgcaatgCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCTTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCTGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGCtcaggcagcggcagcaactgcCGCAGCAATGAGTAAtctcagccagcagcaacagttgcagcattcacattcacatcaCGTCCATGCCCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGTTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTttagctacaacaacaacggcaacagcaacaagcagcaccagcaacaacagttgggCAACAACACTGGCAACTCTTTGGTGATGGACGATGATGAGCCACCCAAGTTGATTATTGACGAGGATGACGAGGATGTGGAGGGAgaggacgatgaggatgaggaggaggagcaggaatTTGATGTCGATGAGGATGAGCAGGAGGATGAAGAGATGGACGTGGACGAtgagcatcagcagcagccgcacgaggaggatgacgatgacgatgatgatgatgttgatgatgatgctgcagcagcagcagcaaaagaggcgtcgcagcagcaattgcagccaaCAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCTCCGAGAAGCAGCCGCACACTCAAGCGGAGTCCCTGAGCGGCAATAAGCCGGCGGCGCctacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTAGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACgtgaactggaactggaacgaGAACGGGAGCgggaacaacaacatttgatcCAACAGTATCGCCAACAAAtggccgctgctgcagcggctgctgttgccgttgccgctgtCGCTGCACCAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGCTCACGACTTCGCACTGCTCCTGGCCAAGGGGGCCATCGAAACGGATGCACAACtccagcatcaacagcagcaacagttgccaatGGCCGGTGGTGCTCCACATTCGGATGatgaggctgctgctgtcggcaCCAGATCGGGCAAGTATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTCCGCCGACACATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacacttgccagaacaacaacaacaacaataacaacaacaatagcaatagtaACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQPQQQQSHTAAATAVAAAAAATQEDARDLGLMETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQPHQQQQQQQLPLSDEEQQQQQQQQLLDSSTQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNINNNISSSSSSSAVAQSAAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQPSQQQQSTQQQQQPQSQSQQQRRQQHAGGADATGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNNNNNNNNNNEDELELEDEQLVLSNKQRRLKAALNNNNIIRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEEQQQQHEEDHEQQHKQEEQEHAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTDADMLTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTATAAATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQAPGFPFFGFLTPPPPATAAAAADKSMPTNPAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAATAAAMSNLSQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNGNSNKQHQQQQLGNNTGNSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEEQEFDVDEDEQEDEEMDVDDEHQQQPHEEDDDDDDDDVDDDAAAAAAKEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKASEKQPHTQAESLSGNKPAAPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREQQHLIQQYRQQMAAAAAAAVAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQLQHQQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNTCQNNNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -