Dsim001351.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila simulans
Gene Symbol
RREB1
Assembly
GCA_016746395.1
Location
NC:4304264-4319507[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.03 1.8 8.8 0.8 1 21 245 265 245 267 0.93
2 13 0.00028 0.017 15.2 0.2 1 23 277 299 277 299 0.98
3 13 6.7e-05 0.0041 17.1 7.3 1 23 305 327 305 327 0.98
4 13 1.2 75 3.7 3.8 2 19 542 559 542 561 0.97
5 13 0.0073 0.45 10.7 0.1 1 23 705 727 705 727 0.97
6 13 1e-05 0.00063 19.7 0.7 1 23 737 759 737 759 0.99
7 13 0.00068 0.042 14.0 2.0 1 23 765 788 765 788 0.97
8 13 0.0024 0.15 12.2 2.0 1 23 1053 1076 1053 1076 0.95
9 13 7.1e-05 0.0044 17.0 0.3 2 23 1446 1467 1445 1467 0.97
10 13 0.12 7.4 6.9 6.3 1 23 1473 1496 1473 1496 0.97
11 13 6.4 3.9e+02 1.5 2.0 1 23 1616 1639 1616 1639 0.83
12 13 0.007 0.43 10.8 0.5 3 23 1696 1716 1694 1716 0.96
13 13 0.0012 0.071 13.2 4.8 1 23 1722 1744 1722 1744 0.99

Sequence Information

Coding Sequence
ATGCTCGCCGCACAGCAAcagcacaacaacagcacagtGGAATCGGAAATGGAGCGCCAGCGACGTGACTCCACCACATCGGAGTCCTCGCTGGAGCATCTGGATCTGGGCCGTACGCCCAAAAAACTGGGCGGCAACAGTGGCTCTGCACAGACCACATCCACGCCACATGAGCTGACTACGGTGACGTCGTCGCGCAAGCGTAAGCTTCGCCATTTGCAATTGaatcaccatcagcagcagcagcatcatcagcagtcGGATCTGCTGAGTGATGAGgacgaggcggaggaggatgaggacgaggaggatgacgaCCAGGTGTCCGCCTTGGGTTCAAGGAATGTGGGACGGCACAAGCAGCGTCGCAGTGGTGGCGCCACCACACAGGCATCCATTGTGGTGGACTACAGCAGTGGCGATGCCAGTTCGCTGCGCAAGAAATTTCGTCTGAATCGCTCGGCGGCCAGTCTCTCGGAATCGGGATTCGTGGACGCCAGCAGCACCACTGGCCACAGTGGCTATCTGGGTAACAGTAGCAGCGCAACGAACACTACTGCCACCAGTGGCATTGGTGCTGGCGCAGTGGCTCCTCCAGTCGGCGGAGCAGCGACCAACGCAgcctccagcagcagcggcagcagcagtggcgGATCCGGTGGCTCCTCGCCCCAGGGACTGTGCCTCTCCAGCGGCGAATCGGGCATCGGAGCCGGCGACGAGCATATGAAATACCTTTGCCCCATCTGCGAGGTTGTCTCGGCCACGCCGCACGAGTTCACCAACCACATCCGGTGCCACAATTACGCCAATGGCGATACGGAGAACTTCACCTGCCGCATTTGCTCCAAGGTGCTATCCTCGGCTTCATCCCTGGACCGACACGTGCTGGTTCACACGGGCGAGCGTCCCTTCAACTGCCGCTACTGCCACCTGACGTTCACCACCAATGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCATCAAGTtgcgcagtcgcagtcgcagcagcagcagtcgctgcagcagcagtcgcagcagcaacagtcacagcagcagcgccgtcagcagcagcaacatcagccgtcgcagcagcagcagaatccCGCCCAGCAGCAATTGGTGGCCAACACGTTATCCGGCCGAGCGGAGAGCTACGAAAGCGATGCCAGCTGCTCCACGGACGTGTCCAGTGGACATAGTcacagtcgcagcagcagttccctcaacaacaacaacaacaactcgcACAAGGCTAACAACAACCTGAAGGACTTGGAGGAGCTGGAAGTTTCGGCTGAGGATCAGGATACGGAGAACAAGCAGCGTCGACTGAAGACCaccatcaacaacaacatcattGAGCgtgagcagcaggaggatATGGATGATGAGGAGGCCGACGATGCGGATGTGGCCATGCTGACCAGCACTCCCGATGTCGCTACTCTTTTGGCCGGAGCCAGTGCATCCGGCGCCGCTTCGCGTTCCCCCACCCCATCGCCATCCGCCTCGCCTGCTTTGCTCCTGAGCTGTCCCGCCTGCGGAGCCTCCGATTTCGAAACCCTGCCCGCTCTCTGCGTCCATTTGGATGCAATGCACTCAGACATACCCGCCAAGTGTCGGGACTGCGAGGTGATCTTTGCCACCCATCGTCAGTTGCAGGCGCACTGTTGTCGCTTACCCAACGCTCTGGGCGGTGGCTTACCTCCGCTCCTCGGAGCCAGCAGTTCGCCGTTGCACAACGAGGAGCCGGAGGATGAGGAGCACGGCGACGATGAGGATCTCGGGCAGAAGGAGAGGATAGCGAGTCAAAGCGAGGACTTTTTCCATCAGTTGTATCTGAAGCAGAAGACAGCAAATGGATGCGGGGCCATCTCGCATCCGCCATCGCCGATCAAACACGAGCCGGCGGACACCAAGGATCTGGCCGATATCCAGAGCATCCTGAACATGaccagctccagttccagtttcCTGCGCAACTTTGAGCAGTCGGTGAACACGCCCAACTCGAGTCAGTACAGCCTGGACGGTAGGgatcaggaggaggaggcacaGGACGCGTTCACCTCGGAGTTCCGTCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTGTGCTCGGCCGTTTTCCCGAACCTTCGTGCCCTCAAGGGTCACAATCGGGTGCACTTGGGCGCAGTGGGTCCAGCCGGACCCTTTCGCTGCAACATGTGTCCCTACGCCGTTTGCGACAAGGCCGCCCTGGTGCGCCACATGCGCACCCACAACGGAGATCGTCCGTACGAGTGCGCCGTGTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGCCATCTGAGGAACCGCCATGGGAAGACCAGTCGCGAGGAGGTGAAGCGAGCCATTGTCTATCATCCGGCGGAGGATGCTGGCTGTGAGGACGGCAAATCGCGTCTGGGTGAAGATCTGGCCGATATGAGTTTCCGTTCGATCAGTCCcacgccaccgcctcctccggTAAATGAGAGCAGCTCCCAGCTGAAGCACATGCTTCTCGGCGAGAGTCACCTGGCTCCTGTTACCCAACAGCCGCCGCTGAAGATCCAGGTGAAGAGCCTCGACCAACTAGTGGACAAGAAGCCACCTGCACCAGCtccccagcagcaacagcagcagcaggagaagaGTGGAGCTCCCCTAGACTTCAGCATGGATGTTTTGGATCTCAGCAAGAAGCCAACTGGCGGAGCATCGCTGACACCGGCGGTCACTCGCACACCGACGcccgctgcagttgctccagtGGCGCCTGGCGGCGTTGGAACTCCTGACCTGGCCGCCGCCAttgagcagcaacagctgctgctggcccaGCAGCAACTCTTTGGAGCTGGCGGCGAATACATGCAGCAGATATTCCGCAGTCTCATGTTCCAGTCCCAGACGACGGGATTCTCGTTCTTTCCCTTCAtggcaccaccaccgccacaaGCAAATCCGGAGAAGCCACCGCTGGTTAGTCCACCAAACCGCCTCAATCCCATGCCCGTGGGCGTTGGAGTCGGCGTGCCAGTGCCACCTGGTGGTCCCGTTAAGATGGTCATCAAGAATGGAGTCCTCATGCCCAAGCAGAAACAACGACGCTATCGCACCGAGCGACCCTTTGCCTGTGAGCACTGCTCGGCGAGATTCACGCTGCGCTCGAACATGGAGCGCCATGtgaagcagcagcatccgcagtTCTACGCCCAACGGCAGAGGAGTGGCCACCATGTGATGCGGGGCAGGGGTGCCTCCAATgtggccgctgctgccgccgctgctgccgccgccgctgcaaCAGTCATGGGTCAGGTGCCGGTTGGCGGACCAGGATCCTCCGGATCCGGCTCCAATCACCATCATGGCCACGGCCATGGTTCCCATGGTTATGCTCCCATTTCGGAGCAGGTCAAGTGCGCCATTCTGGCGCAGCACTTGAAGGCTCACAAGAACACGGATCTGTTGCAGCAGGCTTTGGCCCACGGCTCCAGCAGTGTGGCCGGCAATCCTCTCCTGCACTTTGGCTACCCACTGACCAACCCCAGCTCCCTGAACAATGGTGCCAGCCAGGGCAATGGCCAGGCCACGGCCATGGATGACGATGAGCCCAAGTTGATTATTGACGAGGATGAAAACGAGCATGATCATGAGGTGGAAGCAGAGGACGTGGATGACTTCGAAGAGGATGAAGACGAGGAGGAGATGGATGAGCCGGAAGATGAGCCGGAACTGATTCTAGATGAGCAGCCGGCCGAAAAGGAAGCCgaagaggagcaggagctgcccAAGCCGCTAGAGCAATTGGGTATCAAAGAAGCGGCGCAAAAAATGGCCGAAACCATTTTGGAGCAGGCCATCAAGGCGGGCAAGCCGTCGAgtccaccacccaccaagGAGAATGCCCCGCTCGCCAATCCAACCGTGGCCACAACCATGCAGGAGCCAGCCACTGCTGCGCCCAGTACTAATCCCAGCAGTTTAAAAACGATGATCGCTCAAGCCGAATCTGTGGGAAAATCCCTCAAAGAAGTGGCCAGTTCGCCGTTCAAGGATGAGTCCCAGGACCTGGTTCCAGTGGCCAAGCTGGTGGACAATGCCACCAGCCAGAACATGGGCTTCAACAGCTATTTCCGGCCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAAGAGGGCCTGGTGGCCTCCGGAAGCGCCAGtgagagcaacaacagcggcacCGAGGACGtcaccagcagcagttccagcaGTGAGCCCAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAACCGTGTCTCCTGTCCGTACTGCCAGCGCATGTTCCCATGGAGCAGCTCGCTGCGGAGGCACATCCTCACCCACACTGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGTTGTTCACCACCAAGAGCAACTGCGATCGCCATCTCTTGCGCAAGCACGGCAATGTGGAGTCGGCCATGTCCGTGTATGTGCCCACTGAGGATGTGAGTGAACCGATACCAGTGCCCAAGTCCGTCGAGGAGatcgagctggaggagcagcgacGGCGGCAGGAGGCGGAGCGCGAGaaggaactggagctggagcgcGAGCGGGAGttggagcgggagcgggagctgGAAAGGGAGCGTcagctggagaaggagaaggaacgCGAGCGCCAGCAGCTCATCCAAAAGCTGGCAGCTCAAATGAATGCTGCTGCCGTCGTTGCTGCAGCCTCAGCGGTAAATGGTAGCGCATCTGGAGGACCCCATGGACCCATTGCAGATGCCTTGGCTGGCGGAGATCTGCCCTACAAGTGCCACCTGTGCGAGGGTTCCTTTGCCGAGCGTCTGCAGTGCCTGGAGCATATCAAGCAGGCCCATGCGCACGAGTATGCCCTGCTCCTGGCCAAGGGAGCCATTGAAACCGATTCGCTGGAGGCCAATCCTCACCAGCAGCCGTCGCAGCAGGCCGTGCACTCCGATGACGAGGCTCCGAATGGTGGCGGTAACCGGGGCAAGTATCCCGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGTCGCTTCTGGTCTACCGAGGATCTGCGTCGCCACATGCGCACCCACTCGGGCGAGCGGCCATTCCAGTGTGATATCTGCCTGAGGAAGTTCACACTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGTAGGGCCCACAATGGGGATACACCGGGATCCGACTGCTCCGACGACGAGCAGGTGAGCAGCCCGCCCAGCACACCGCTTCCCACCCAGCCGACcagcgccaacaacaacaacagctgtcacaataacaataataataccaacaacaataacaacaacaacggcagctcCAAGCTGGGACTTAAGCTCCACGACCTGCTGGACAAGGCGAGCGAATGGCGGGCCAGTCGCCTGGGCGAGCACAAGGAGAACATGGGCGAGGCCACGCCCTCGGGAGCAGCGGTCGCTGGTTCGGATCTGATTGGCAATCTATTGGGCATCAGTGACCAGGGCATTCTCAACAAGCTGCTCTCCTCCGCCGACGAGGCGGCCAAACTTCTGGGTGTGGACAACAAGTGA
Protein Sequence
MLAAQQQHNNSTVESEMERQRRDSTTSESSLEHLDLGRTPKKLGGNSGSAQTTSTPHELTTVTSSRKRKLRHLQLNHHQQQQHHQQSDLLSDEDEAEEDEDEEDDDQVSALGSRNVGRHKQRRSGGATTQASIVVDYSSGDASSLRKKFRLNRSAASLSESGFVDASSTTGHSGYLGNSSSATNTTATSGIGAGAVAPPVGGAATNAASSSSGSSSGGSGGSSPQGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQVAQSQSQQQQSLQQQSQQQQSQQQRRQQQQHQPSQQQQNPAQQQLVANTLSGRAESYESDASCSTDVSSGHSHSRSSSSLNNNNNNSHKANNNLKDLEELEVSAEDQDTENKQRRLKTTINNNIIEREQQEDMDDEEADDADVAMLTSTPDVATLLAGASASGAASRSPTPSPSASPALLLSCPACGASDFETLPALCVHLDAMHSDIPAKCRDCEVIFATHRQLQAHCCRLPNALGGGLPPLLGASSSPLHNEEPEDEEHGDDEDLGQKERIASQSEDFFHQLYLKQKTANGCGAISHPPSPIKHEPADTKDLADIQSILNMTSSSSSFLRNFEQSVNTPNSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDGKSRLGEDLADMSFRSISPTPPPPPVNESSSQLKHMLLGESHLAPVTQQPPLKIQVKSLDQLVDKKPPAPAPQQQQQQQEKSGAPLDFSMDVLDLSKKPTGGASLTPAVTRTPTPAAVAPVAPGGVGTPDLAAAIEQQQLLLAQQQLFGAGGEYMQQIFRSLMFQSQTTGFSFFPFMAPPPPQANPEKPPLVSPPNRLNPMPVGVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNVAAAAAAAAAAAATVMGQVPVGGPGSSGSGSNHHHGHGHGSHGYAPISEQVKCAILAQHLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLTNPSSLNNGASQGNGQATAMDDDEPKLIIDEDENEHDHEVEAEDVDDFEEDEDEEEMDEPEDEPELILDEQPAEKEAEEEQELPKPLEQLGIKEAAQKMAETILEQAIKAGKPSSPPPTKENAPLANPTVATTMQEPATAAPSTNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMGFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAEREKELELERERELERERELERERQLEKEKERERQQLIQKLAAQMNAAAVVAAASAVNGSASGGPHGPIADALAGGDLPYKCHLCEGSFAERLQCLEHIKQAHAHEYALLLAKGAIETDSLEANPHQQPSQQAVHSDDEAPNGGGNRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQVSSPPSTPLPTQPTSANNNNSCHNNNNNTNNNNNNNGSSKLGLKLHDLLDKASEWRASRLGEHKENMGEATPSGAAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00605068;
90% Identity
iTF_00539880;
80% Identity
-