Basic Information

Insect: Drosophila silvestris
Gene Symbol: RREB1
Assembly: GCA_035043445.1
Location: JAWNMZ010000039.1:772604-779545[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.006 0.4 11.2 0.6 1 21 277 297 277 299 0.96

2 13 0.00035 0.023 15.1 0.2 1 23 309 331 309 331 0.98

3 13 0.00026 0.017 15.5 7.2 1 23 337 359 337 359 0.98

4 13 0.24 16 6.1 1.7 2 20 590 608 590 610 0.93

5 13 0.016 1.1 9.8 0.2 1 23 759 781 759 781 0.97

6 13 1.3e-05 0.00084 19.6 0.7 1 23 791 813 791 813 0.99

7 13 0.00086 0.057 13.9 2.0 1 23 819 842 819 842 0.97

8 13 0.0031 0.2 12.1 2.0 1 23 1124 1147 1124 1147 0.95

9 13 8.9e-05 0.0059 17.0 0.3 2 23 1542 1563 1541 1563 0.97

10 13 0.15 9.9 6.8 6.3 1 23 1569 1592 1569 1592 0.97

11 13 9.7 6.4e+02 1.1 3.4 1 23 1710 1733 1710 1733 0.78

12 13 0.0087 0.58 10.7 0.5 3 23 1793 1813 1791 1813 0.96

13 13 0.0014 0.091 13.2 4.8 1 23 1819 1841 1819 1841 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.006	0.4	11.2	0.6	1	21	277	297	277	299	0.96
2	13	0.00035	0.023	15.1	0.2	1	23	309	331	309	331	0.98
3	13	0.00026	0.017	15.5	7.2	1	23	337	359	337	359	0.98
4	13	0.24	16	6.1	1.7	2	20	590	608	590	610	0.93
5	13	0.016	1.1	9.8	0.2	1	23	759	781	759	781	0.97
6	13	1.3e-05	0.00084	19.6	0.7	1	23	791	813	791	813	0.99
7	13	0.00086	0.057	13.9	2.0	1	23	819	842	819	842	0.97
8	13	0.0031	0.2	12.1	2.0	1	23	1124	1147	1124	1147	0.95
9	13	8.9e-05	0.0059	17.0	0.3	2	23	1542	1563	1541	1563	0.97
10	13	0.15	9.9	6.8	6.3	1	23	1569	1592	1569	1592	0.97
11	13	9.7	6.4e+02	1.1	3.4	1	23	1710	1733	1710	1733	0.78
12	13	0.0087	0.58	10.7	0.5	3	23	1793	1813	1791	1813	0.96
13	13	0.0014	0.091	13.2	4.8	1	23	1819	1841	1819	1841	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcagcaacagcagcagcagcaacaacaacagcaacaatcgcaCACAGcatctgcaactgcagcagcagcagcagtagcagcaacacatGAAGATGCTCGGGATTTGGAGTTAATGGAAACGCGACAGCGTCGCGATTCGAGCACCTCAGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCAACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGCAAACTGCGacagcaacaccaccaccagcagcagcagcagcagcaacagtcgccaCTCTCCGatgaggagcaacagcagcaacagcagcagcagctgttggacTCATCAGCGCAGCGACCGCGTCACAAGCAGCGACGCAGCgccgttgctgccgctgccagcgCCAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAGTCGGGTTTCGTTGATGGCAGCGCCCTCAGTGGCTATCTgcttggcagcaacaacaacaacaacaacaataataataacaacaacaacaacaacaatatcagtaatagtagcagcagcagcagcgcagtcgctcagtcagcagcagcagcagcagcgtcggcaGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTTTCGAGCGCCGAGTCGGGCATCGGTGCCGGCGATGAGCACATTAAATATGTGTGCCCCATTTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAggcgtcgcagcagcagcagcagcaacagcagcagcactcgcaacagcagcaatccacacaacagcagcaacaggcacagtcgcagtcgcagcaacagcaacagcgacgccAGCAACATGCGggtggagcaggagcaactgGCTCGATATCGGGATCAGCACAGTTGCTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaacaatagccacaaaacgaacaacaataacaataacaacaacaacaacaatgaggaTGAGCTCGAGCTGGAGGATGAGCAGCTAGTGCTGAGCAGCAAACAGCGACGCCACAAGGCAGccctgaacaacaacaatataattaGGGATGAGGAGCACGAGAATCGGCCGGATGATGATTCGGATGTGGACAGCGCTGATAGCGTTGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATCGCATTCACCgcccctgctgctgcagagctGCCCGGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAGTGCGAGGTGATCTTTGCCACACATCGACAGCTGCAGGCGCATAGCTGTCGAGGATTGCCGCCGCTGCTTGGTGTGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAACTGGaggagcagcaccagcagcagcagcagcacgaggaggaggaccacgaacagcagcagcacaagcaggaggaacaggagcaggctGAGCAGCGCGAATGCGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTGCTTCCCTCACCGATCAAACATGAGCCGGCGGACCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGGCGAATGAAACTGCGCGGTGAGTTCCCCTGCAAGCTGTGCACCGCCGTCTTTCCCAATCTGCGTGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCTGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCCGCGCTCGTCCGGCACATGCGCACCCACAACGGCGATCGGCCTTACGAGTGCGCCGTCTGCAATTATGCGTTCACCACCAAGGCGAACTGTGAGCGTCATTTGCGCAATCGACATGGCAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCGCGGACCGAAGCCGATATCCTAACGGAGCTGGGCGGCTATCGTTGTGCAACACCCACGGAGCACAGCTCCTCGGCTAGCTCCTCGTCACAGCTGAAGCACATGTTGCTGGCGGAGCCGACGCCGGTCATAAaggtagcagcaacaacagctgcagtagcagcagcagcagcagcaacaacatcgctGCCACAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCAGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCCCAGCTGCTGGCCGAGCAACGGGAGCAAAGGGAGCAGCTCGAAAGACACGAATtggtgctgcagcagcaacagcagcagcaacaacaacagctgcagcagcagcagcaacagcagcagcagcaacaaatgtttGGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGAAACTTCATGCTCCAGCAATCACCCGGTTTTCCCTTCTTTGCGTTTATggcgccaccgccaccaacagcggcagcagcagcagcagcagcagcaacagcagcagacaaatCAATGACAATaaatccagcagcagcagcagcagcagccggcgcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCTGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGAACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACCCTGCGCTCCAACATGGAGCGCCATgtaaagcagcagcatccacagtTCTATGCGCAGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGACTGCATCCTCGAGTGCTGTCCAAGCGGCAGCCGCtgcacaggcagcagcagcagcagccgccgccgcagcaatGAGTAAtctcagccagcagcaacagttgcagcactCGCATTCACATCATGTCCATGCGCCAATCTCGGAGCAGgtgaaatatgcaattttgGCGCAGCAATTGAAGGCACGCAAGGATACCGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCGCCAATCCGCTGTTGCATttcagctacaacaacaacaacaacagcagcagcaacagcatcggcaacaagcagcagcaacaacagttgagCAACAACACTGGCAACTCTTTGGTGCTGGACGACGATGAGCCGCCCAAGCTGATCATTGACGAGGATGACGAGGATGTGGATggcgaggaggatgaggatgaggaggaggagcaggaatttgatgttgatgaggaggagcaggaggatgAAGAGATGGACTTGGACGatgagcatcagcagcagctgcacgaggaggatgatgatgatgatattgatgatgatgatgcagcagcaacagcagcaacagcagcagcagcagcagctgcagctgcagcagaggcgtcgcagcaacaattgcagccaaCCAAGGACAAGCTGCAAGCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCGGCCGAGAAGCAGCCGCATCCTCAATCGGAGTCCGTGGGCGGCAATAAGCCGGcggcgccaacaacaatgaaaacgaTGATTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCCAGCGACGTTGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaatGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGTTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAGGCCGAACAGGCCGAGCGTGAGCAGCGCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAAttggaacgggaacgggaacgggaacacCAACAGTTGATACACCAGTTGCGCCAACAAatggccgctgctgcagcggctgctgtcgctgttgccgcCGTTGCTGCACCAACGCATCCACCACCGCCGGCCCAATCGCCGCCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAGTTCTCATTCGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTGCACGCACACGAGTTCgcactgctgctggccaagggGGCCATCGAAACGGATGCACagctccagcaccagcagcagcaacaattgccagtGGCTGGTGGTGCTCCACATTCGGATGATGAGGCTGCCGCCGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAGCTCGATCATCAGTCCGATTGCTCCGACGATGAGCAGCTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacaacacttgccagaacaacaacaacaataacaataacaacaacaatagcaatggcaAGCAGGTGCTGCGCGAGCTGCTGGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGCGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTGGGAGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQQQQQQQQQSHTASATAAAAAVAATHEDARDLELMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHHHQQQQQQQQSPLSDEEQQQQQQQQLLDSSAQRPRHKQRRSAVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGSNNNNNNNNNNNNNNNNISNSSSSSSAVAQSAAAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHIKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQQQHSQQQQSTQQQQQAQSQSQQQQQRRQQHAGGAGATGSISGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNNSHKTNNNNNNNNNNNEDELELEDEQLVLSSKQRRHKAALNNNNIIRDEEHENRPDDDSDVDSADSVAQVITSTPDVATLLASGGTSPTHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEESELEEQHQQQQQHEEEDHEQQQHKQEEQEQAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTEADILTELGGYRCATPTEHSSSASSSSQLKHMLLAEPTPVIKVAATTAAVAAAAAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELVLQQQQQQQQQQLQQQQQQQQQQQMFGAGDAAAQYMQQLLRNFMLQQSPGFPFFAFMAPPPPTAAAAAAAAATAADKSMTINPAAAAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRHRSGHHVMRERTASSSAVQAAAAAQAAAAAAAAAAMSNLSQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNNNSSSNSIGNKQQQQQLSNNTGNSLVLDDDEPPKLIIDEDDEDVDGEEDEDEEEEQEFDVDEEEQEDEEMDLDDEHQQQLHEEDDDDDIDDDDAAATAATAAAAAAAAAAEASQQQLQPTKDKLQAKPIEAAKKVAETILEQAIKEREEKAAEKQPHPQSESVGGNKPAAPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREHQQLIHQLRQQMAAAAAAAVAVAAVAAPTHPPPPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQLQHQQQQQLPVAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNNTCQNNNNNNNNNNNSNGKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -