Basic Information

Insect: Drosophila siamana
Gene Symbol: hang
Assembly: GCA_035047445.1
Location: JAWNPP010000078.1:4104741-4120271[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.36 22 5.6 1.0 3 23 574 595 573 595 0.93

2 18 0.46 28 5.3 3.2 3 22 702 721 700 721 0.89

3 18 0.00079 0.047 14.0 3.3 1 22 819 840 819 842 0.90

4 18 0.071 4.3 7.8 0.1 2 21 854 873 853 874 0.93

5 18 0.00091 0.055 13.8 0.2 2 23 1024 1046 1023 1046 0.95

6 18 0.0026 0.16 12.3 0.1 1 23 1054 1077 1054 1077 0.96

7 18 2.1e-05 0.0013 18.9 0.1 2 23 1163 1184 1162 1184 0.97

8 18 0.00038 0.023 15.0 2.9 2 23 1279 1301 1278 1301 0.97

9 18 0.016 0.95 9.9 0.9 2 23 1310 1332 1309 1332 0.96

10 18 0.0018 0.11 12.9 0.3 1 23 1345 1368 1345 1368 0.97

11 18 0.00016 0.0099 16.1 1.1 1 23 1419 1441 1419 1441 0.99

12 18 0.0025 0.15 12.4 0.9 1 23 1449 1472 1449 1472 0.96

13 18 0.35 21 5.6 0.3 2 19 1480 1497 1479 1498 0.93

14 18 3.5e-05 0.0021 18.2 0.4 3 23 1597 1617 1596 1617 0.98

15 18 0.0066 0.4 11.1 0.1 1 23 1652 1674 1652 1674 0.97

16 18 0.00078 0.047 14.0 0.6 2 23 1763 1785 1762 1785 0.93

17 18 0.0084 0.51 10.7 0.3 3 23 1841 1861 1841 1861 0.98

18 18 4.8e-05 0.0029 17.8 2.5 1 23 2240 2262 2240 2262 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.36	22	5.6	1.0	3	23	574	595	573	595	0.93
2	18	0.46	28	5.3	3.2	3	22	702	721	700	721	0.89
3	18	0.00079	0.047	14.0	3.3	1	22	819	840	819	842	0.90
4	18	0.071	4.3	7.8	0.1	2	21	854	873	853	874	0.93
5	18	0.00091	0.055	13.8	0.2	2	23	1024	1046	1023	1046	0.95
6	18	0.0026	0.16	12.3	0.1	1	23	1054	1077	1054	1077	0.96
7	18	2.1e-05	0.0013	18.9	0.1	2	23	1163	1184	1162	1184	0.97
8	18	0.00038	0.023	15.0	2.9	2	23	1279	1301	1278	1301	0.97
9	18	0.016	0.95	9.9	0.9	2	23	1310	1332	1309	1332	0.96
10	18	0.0018	0.11	12.9	0.3	1	23	1345	1368	1345	1368	0.97
11	18	0.00016	0.0099	16.1	1.1	1	23	1419	1441	1419	1441	0.99
12	18	0.0025	0.15	12.4	0.9	1	23	1449	1472	1449	1472	0.96
13	18	0.35	21	5.6	0.3	2	19	1480	1497	1479	1498	0.93
14	18	3.5e-05	0.0021	18.2	0.4	3	23	1597	1617	1596	1617	0.98
15	18	0.0066	0.4	11.1	0.1	1	23	1652	1674	1652	1674	0.97
16	18	0.00078	0.047	14.0	0.6	2	23	1763	1785	1762	1785	0.93
17	18	0.0084	0.51	10.7	0.3	3	23	1841	1861	1841	1861	0.98
18	18	4.8e-05	0.0029	17.8	2.5	1	23	2240	2262	2240	2262	0.99

Sequence Information

Coding Sequence: ATGTGCGACgctgccgcaacaacaacaacgatagcagtaggaggaggaggagtcgGAGGAACCATTGGATCTGCTGACACAGGAGCGATATCTATGgatgaacagcagcaggcggaaCGTCAGCGACAaagctgctgtcgcttgtGCATTGCGCCCGCCAGCGAATGCATATCGATCATCAATAGTTATGCAGCCGATAAGGAGCCGCTggccacaaaaatacataacTGCGTAAATATCAAGATCACATCAACGGATCGTCTATCAGTGCACATTTGCCACGCCTGCATCAGCTATTTGAATTCGTGGCAAAGTTTCAAGAATCGCTGCCTCAGCTCACAGACGAAGCAACGCCAATGGCTGGACACGGATCGCACCAAACAGCAGACGCTCCTCGGCTACTTGGATTTAAATCGGGCCGAGAATGGTGGCAGCGTCGCTGTCACAgttgagcaacaacagcaagctgCCGAATTGAAAAACgatgcaacagctgctgagAAGGCGTCCGCGAACATTTTGGATGGCATACCATCGCTGAAGAAGCGCAAATCGTTAACAGTCTATGTGAGtcccaagcagcagcaactgcaactgcaacaacagcagcaacaacaacaacaacatcagcagcagcagcagcagcagcaacaactgctgcaaaCGTCGGCAAGAGCAGCGGcagagcagccacagcaacaaacttTGCAGACCCTTTTATTGCAGGTGCCCTCCACGTTTAGCACAACtgcggcaatggcaacgtcacaatcgcaatcgcagcaacagcagcaacgcaagtatcaacagcaacagcagcagcagcatcagcaacgtGTTAAGCAGTCATTctcccatcatcatcagcatcatcatcaccatcatcagcagcagcagcagcaacagctgcaaatgcagcagcgaCATCGACGCATTCGCCAGCCGCGACGTCAGGTGGCGCCATCTGCTGTTGCTCACCAGCAGCGTTTGTCCAAGCTGAAGCCCAAGGTCTATTTACCGTTAGACATTGCAGTGCCGCCATTGCCACCGATACCAATACCGATACCGATGACAACGCCCGTGTTATCGTccgttggtgttgctgcttccactgcttctgctgctgctgttgctgctgaggcAGCAGcttcgttgccattgccgttgtcgtcgtcgtcgtcgtcgctgcccaTTGATTTCAGCCAGTGTAAGAATCAAAACTCGAATCCGTCTCAAAAATTTAGCGGCAACGTCGTCTTGCCGcttccgccgccgccgccgctgccgtcaTCGTCAGTTGCCacaatgagcagcagcagcagtggcaatgCCGTCGCAATCCCTAGCGCCGCTACTGCTGCTTCGGCGTCGGCgtctgccgctgcctctgcctctgcctctgccactgccactgccacaacaaccacagcagtaacgacgccgctgctgatgcCGCCGCTGCCCGCCGTGCCCATCAAGGATGAGCCGCTGGACGATACGGACGATGACTTTCAGATGAAGTGCATTGACGAGTCCGACGACATGATGGATCCCACTATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCGCTAATGACCTCCGACTATGATTATACGGCGCAGCACGGCGTGACGGCGGCCGTGGCGGCGGCATCGCTGCCCGCGAGCGCCGTGGCCAATGTGGCAGCCGCCGGTGACTCGAAGGTGGCCAGCTGCCGGGCCTGCAGTCTGCAGTTCTCGACACGCGCAAACGCGCGACGCCACGAACGCAATCTGCATCCCAATCTGTTCCAGCTGTCGACCGATTCGCCCAACAATACGCCAATCACAAAGCCAACGCCGGCGCTCGCTGCCGCACTGGAGATCCAACGGGCCgcggctgcagcggccgcAACGGCGGAGGCAACCAAGGCGGCGGCCGGGGGCAACATCTCGACCCAGAAGTACCGTCAGGTGGTGATGAACACGTTCATCAAGTGCGAGAACGGCGGCTACGACTACGACAATCCGGAGCAGTATCAGCAGCTGTTGACGCGCGACAAGGTCGAGTTCATACAGGAGAACAATGAGTTTCTCGAGCAGTACCAGACGATGACGTGTCGCTGTTGCAACAAATACTTCAGCACCTACAAGAATTTCATGGCGCACGTGCGCAAAAAGTATCCGATGTTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTCTTCATATCGCATCTGAAGAAACGCAACTGCATCAATCTGTACCGTGTGCTCAACGCGCTGCGCCTCAAGCAGCCCAACTTTGCGCACGCGAACGCCGCCGGCGTTGTGGCCACCACcgagccgcagcagccgcaacagcagcaattgtcGCTGGTGCACGACACGTCCTCGTCGTCGGACCGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAACAAGCTGTACGAGTGCAAGCTCTGCCCCAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTGTACGACAAGCATGCGGACGTGCAGCGCAAGGACAACAATTCGATACAGTGCAGCTTCTGCGGCCTGGACTTTGCCAATCCCGTGGACCGACGGCGCCACTACAACAACATGGACTGCATTGTGCGGCTGCGTTGCATGACCTGCGACGCCAAGCTGGAGACGCATCAGCGTTTCCTCGACCATGTCTATCACGACCATCTCGGCGGCGACAATGCGTCGACGGCGAACAGTGCGCTCGACCATTCGCCGGGCAAACGCAGTTTGCTGGGCGCCCTCGGCATCGGCGTCAGTCAGTCGTCCAACGACGAGTcgcgcggcagcagcagcaccaacatcAACgtcagcatcaacaacaacaacaacaatcacaatgccagcaatgtgactgctgctgttggagccGATGGCAGCCCGTTGACCTCGACGCCGTCGAAGCCTGTGCCCAACTCGTCGGGCGGCTCGAACTCGGCCAATCGCAGCgttggcggcggtggcggtggcggtggcgtcAGCGATTCGGCGCCCAAATCGCAGTATTTCTCGCGCATGCCGCAGGTTTGCCCCATCTGCGGGCAGCagtacaacaactacaacaacgtgCTGCGGCACATGGAGTCGAAGCATCCCAACAAACTGCCCGAGACGTACAAGTGTGTGCGGTGCGGCCTCGGCTATCCACGGATCTCATATCTGCGCGAGCACATGATCAATGTGCACGGCGTGGACAAGAATCGGCATTCCGGCGGCTTCGAGTACATCGTGAATGCGGCCGCCGTGAAGCTGGCCGACGGCAGCACGCCGAACGTCTACACGGGACGCTACGATTATGTGATGAAGGATTTAATGTCGATAACAAATGGTGGGACACTcgatgacgacgacgaggagacCGGCAGTCTGGCCAAGAAGATACGGctcgacgacagcagcaacaacagcagcatcaacaccAGCATTGCCAACCAGCAGAAGGAGTGCCCCATCTGCAATGCCGTcttcagcaacaacatcggcCTCTCGAATCACATGCGCTCGCATTACACGGCCTCCTCGACGGCGACGAATGCGGCCCTGGCCGCTGCCAATCGCATGACACCCAAATCGCTGACCATCACAGCAACGCCGCCGCTGGATGTGGCCACAAACGTGGCCAGCACAAacactgcagcagcatcgccaTCGGCGATCGGCAGTGGAACGCCGGCAGCGACGCCAACGGGCGGCAAAGTGCCGCCAGCGATGGTCCACCAGACGCCGCAGGAGCAGGCCGTGTTTCGGCGCAGTCTCGACCAGGCGGCGGATCGACGCTTTCGCCGCATGCGCTGTCGCATCTGCCAGCGTCGCTTCAGCTCAAAGAAGTCGTATCGCTACCACATGCTGACCGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCCGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCATCTGTGCAAGGTGCACGGTCGGACGATCAAGGACGAGATGATTGTCAAGCAATTCGAGTGCGATGTCTGCTCCACCGTCTACAGctcggagctggagctgcagcagcacaagcgCAGCGTCCACAAGTCCAGCGCCAATAGCAAGTCGTCGACGACgataacagcgacaacgacaatgacaacgacgtCCAACGCAACGATCGCGGCGAGCTCGGCGGCTGCAGCGTCTGGGGAGCTGGCGGGCGACACGTCGATGGTGTTGCCGCTGTATTGGTATCAATGCAAGTACTGTCCATCCAATTTCAACACCAACAAGAAGCTGGCCATCCACATCAATTCGCACGACGAGTTCGACTCGAACGATTACTCGTGCAAGGACTGCGGCAACGTTTACAGCGGTCGCAAGAGCCTCTGGGTTCATCGCTACAAGAAGCATCCACAGGTGCCCGACCCGGTGGAGTGCACGCTGTGCCGCAAAATGTTCTTCGACCGCCAGATGCTGGACAATCACACGCCCACCTGCAACCGCAAACCCATCACGGCCACCGGCGCCCATCAGCAGGatgcccagcagcaacagcagcgcgaTCATCtccagcagccgcagcgtGGCATCTTCAAGCACAAAAcgggcgacgacgatgacgaggatgaggacgacgaacagctgctgctgctcgacgatGCGGGCGGCGTTGTGGGCGCATCAACAGCTGGCGGCGGAGCAGCAGGAGACGCAACCGCTGTGGGTAGCGATGGCAACGCGACGTCGCTGGCGGGGCTTAAGATACGCATACCGGAGGTGGCGTGCACGATTTGTGGGGCACGCTTCACCGACCAGGAGATGTTCACGAAGCACATACAGAAGCACGAACAGGAGCTGTATGTGGACAATCCACTGGCGGCGATGTTCGACGATGGTCCCGCTGATGCGGGACAGTTTCAGGTGGAGCGTCAGAATGAGAACGGCGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCGCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAACgctgaacaacagcagcagcagcaacaacaacaacaacaactcgatgCTCCATCTGCGCGAACTGCATGCGGTGGGTCTGATGCccaaccagcagcaacagcatcagaagcagcagcaacaacaacagcagcagcagcaactgtccCAATCCCAGCAGCAATcgagccaacagcagcagcagcggaacAAGTCGCTGAAGCGGAAACGTGAGCTGAAATGTGAATATTGCGCCTCCACCTtcattagcaacaacaacctgCGTCGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATCTGCCCGAGCCGCCAGTCATTCAAGTGGACGCGCCCCTCAGCTGTCGTCGCTGCGGCGACCTCAAGTTCGAGTCGAAGGAGGCGTGGATCGAGCACAAGCTGGCCGACGCGAAGGTGGTGCGTCCGTTCTGTCCATTCCAGTGGGGCTGTGATCTGTGTGGCGAGTATCTGTCGCGCAAGGAGAAGCTCATCAATCACATCAACAATCATCTCAAGGAGGAGGTAATTGTGCCCGTTGCGGTGGCCAAAAACAAGCTCGACAcgctaacagcagcagccgcagccgcagccgcatcAGCTGCACCGGCTGaggaagcaacagcagcagcaaagacaacaacaacaacaacaacgacaacaatgaaggctgcagcaacagcggctgGAGCAGCTCAAGGTGGCCTTAAAGCGAAGCCAAAGAGcgagacaacaacgacaacagcaacggagGCAACGGGCAAACGGGCCGAGGTGGACAGTGAGCTCGAGGATGACAGTGATagcgacgatgatgaggatgacgatgacgaggagGATAGCACGAGtgccgacgatgatgatgaggaagGGGACGTCGACGATGAGGAGGACGATGATGTTGAGGACGATGAAGATGCagttaagcagcagcaacaacgacacaacaacaacaacaacaacaaaagtagtggtaacaataataacaacaacaacagtgccGCCTTGGATGAGGATGATCTCATCGAGGAGGTCATTGAGGAGATCGACGATgtggacgaggaggaggaggaggaggagcgggagcagcagcagcagcaggtcgAACATGTTGGTGGCAAAACCAAATCGACAACAACGAAGCGTCACAACTTTGAGTACAATGAGGCCAAGTTGaatggcaacagcaagcagcagacgACGCACAGCTCCGAGGACGAtggcgaggaggaggaggtggacgatgacgacgacgaggacgatgacgacggcgaggatgaggatgaggatgacgtCGAAATGGACGAGGAGGAGGTTGAGGGTGGCGTCAATGTCGCTGTCGGCGAAGGCATGACCATTGATGATATTATCGAGGAGGATGATggcgaggacgacgatgaggatgatgacgatgagcaTGGACAGCATCTAGTTGGCGAGCATGTCGTGGCcgaggacgatgacgacgacgtggatgatgataatgatgggaatggcgacggcgatggtggcacatcgtcgtcgtccgaGAGCGAGTCGACAACGACCACGTCGCAGTCAACTGGTGAGCGgcgcaataaaagcaaatctGTAGTTTCATCATCAGCGGCATCAGCGGCCGCTGCTGATCACACTAATAATTCCAGCTATACGTGCGATCTATGTCAACTTTGTTTCGATTCccaggagcagctgcagacCCATATTAAAAGCCATTTCCTCAACGGGCCAACAACGACAccgggcagcggcggcggcggcggcggcggcggcaacggcagcggcagcggcagcagcagcgccgccagtcgcagcagcaatagTCAccaaagcagccgcagcaggagcagcacctccaataacaacaataataacaacaacaacagcaatcacaaccacaaaagcaaaaccaaaaaggagacagcagcagctgcagcgacggttgcgtcgacagcggcagcatcagcaacggtggcggctgcagcagcgactgcagctgcgacCGCCACGGATGCTGATGCGAGCTTCAACTGA
Protein Sequence: MCDAAATTTTIAVGGGGVGGTIGSADTGAISMDEQQQAERQRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITSTDRLSVHICHACISYLNSWQSFKNRCLSSQTKQRQWLDTDRTKQQTLLGYLDLNRAENGGSVAVTVEQQQQAAELKNDATAAEKASANILDGIPSLKKRKSLTVYVSPKQQQLQLQQQQQQQQQHQQQQQQQQQLLQTSARAAAEQPQQQTLQTLLLQVPSTFSTTAAMATSQSQSQQQQQRKYQQQQQQQHQQRVKQSFSHHHQHHHHHHQQQQQQQLQMQQRHRRIRQPRRQVAPSAVAHQQRLSKLKPKVYLPLDIAVPPLPPIPIPIPMTTPVLSSVGVAASTASAAAVAAEAAASLPLPLSSSSSSLPIDFSQCKNQNSNPSQKFSGNVVLPLPPPPPLPSSSVATMSSSSSGNAVAIPSAATAASASASAAASASASATATATTTTAVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAAVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPMLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFAHANAAGVVATTEPQQPQQQQLSLVHDTSSSSDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFANPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYHDHLGGDNASTANSALDHSPGKRSLLGALGIGVSQSSNDESRGSSSTNINVSINNNNNNHNASNVTAAVGADGSPLTSTPSKPVPNSSGGSNSANRSVGGGGGGGGVSDSAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNAAAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEETGSLAKKIRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTATNAALAAANRMTPKSLTITATPPLDVATNVASTNTAAASPSAIGSGTPAATPTGGKVPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLCKVHGRTIKDEMIVKQFECDVCSTVYSSELELQQHKRSVHKSSANSKSSTTITATTTMTTTSNATIAASSAAAASGELAGDTSMVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPVECTLCRKMFFDRQMLDNHTPTCNRKPITATGAHQQDAQQQQQRDHLQQPQRGIFKHKTGDDDDEDEDDEQLLLLDDAGGVVGASTAGGGAAGDATAVGSDGNATSLAGLKIRIPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSSNNNNNNSMLHLRELHAVGLMPNQQQQHQKQQQQQQQQQQLSQSQQQSSQQQQQRNKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIQVDAPLSCRRCGDLKFESKEAWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEEVIVPVAVAKNKLDTLTAAAAAAAASAAPAEEATAAAKTTTTTTTTTMKAAATAAGAAQGGLKAKPKSETTTTTATEATGKRAEVDSELEDDSDSDDDEDDDDEEDSTSADDDDEEGDVDDEEDDDVEDDEDAVKQQQQRHNNNNNNKSSGNNNNNNNSAALDEDDLIEEVIEEIDDVDEEEEEEEREQQQQQVEHVGGKTKSTTTKRHNFEYNEAKLNGNSKQQTTHSSEDDGEEEEVDDDDDEDDDDGEDEDEDDVEMDEEEVEGGVNVAVGEGMTIDDIIEEDDGEDDDEDDDDEHGQHLVGEHVVAEDDDDDVDDDNDGNGDGDGGTSSSSESESTTTTSQSTGERRNKSKSVVSSSAASAAAADHTNNSSYTCDLCQLCFDSQEQLQTHIKSHFLNGPTTTPGSGGGGGGGGNGSGSGSSSAASRSSNSHQSSRSRSSTSNNNNNNNNNSNHNHKSKTKKETAAAAATVASTAAASATVAAAAATAAATATDADASFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589676;
90% Identity: -
80% Identity: -