Dser002819.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Drosophila serrata
Gene Symbol
ftz-f1_1
Assembly
GCA_002093755.1
Location
NW:698333-749856[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 3 1.4e+04 -6.3 14.0 32 163 21 155 7 211 0.57
2 4 3 1.4e+04 -10.1 18.1 51 159 220 349 183 361 0.44
3 4 5.4e-19 2.6e-15 56.4 0.5 1 76 568 643 568 676 0.74
4 4 9.2e-70 4.4e-66 223.7 1.5 157 408 788 1031 773 1033 0.92

Sequence Information

Coding Sequence
ATGGATACCTTCAATGTACCTTCAATGCTGGCGGAAAGCAACGGCACCAACTATGCAACAGAAGCTACCAGCAACCATCACCacctgcaacagcagcagcagcaacatcagtcCCTGTTGCTGCCCCATCATCACAAGGATCAAATGCTAGCCGCTGGCAGTACACCAATGCTACCATTTTACTCCCACCTGCAGATGCAGCAAAAGGATGCAACTGGGACaccaacggcagcagcagcaccagcagcatcTGCAGCAGATAACTTTAGCACATTGCAGGCAATCGATGCCAGTCTGGATGGCGGCATATCCTTGAGCGGACTCTGCGAACGCTTCTTTGTGGCCAGTCCAAATCCACATAGCAACAGTAATAATATGACCCTAATGGGCACTGCGTCAGCGGCAGCAACTACCACTGCAACGGCTACTACAACtaccaataataataatactactaaaaacaatgTGGAGGCTAAGGCAGTGAGACCATCAAATTCGGTGATTATTGAATCCGTGACGATGCCATCTTTTGCCAACATTCTCTTTCCCAATCATCGCACCAATCACCAGCAAGAGTGCATCGATCCAACTTTGCTGCAAAAGAATCCtcagaataataataataataataataatattgtacCACCCGTGGAGTATCATCAATTGAACCCCTTGAGGGTCAACTCCTCTTCAACTTCCGGTTCTGTGTCAACCAGCAATTTCCTCTCCTCCACCACAGCCCAGTTGCTGGACTTTGAGGTGCAAGTGGGCAAGGATGATAGTCACATTATCAGTACCACAACCACAACGGCtacgggatcgggatcgggatctgGTTCcggatcaggatcaggatcagcaACATCCACAACGACCACTGCCAATCCGACGAGGAGCTCGTTGCACAGTATTGAGGAATTGGCTGCCAGTTCATGTGTCCCAAAAGTCACATCGCCCAATAATAGCAATAATAGCAGCAATGCCAGTACAAcaccacagcagcaacactccagcagccagcagcagcagcagcagcaacatcacaTGCAAAGTGGCAACAATAGTGGCTCTAATCTCAGCACCGATGATGAGTCCATGTCCGAGGGATTCGGTCTAGAAATCGATGATAATGGGGGCTATCAGGACACCACCTCCTCGCATTCCCAACAAAGtgctggcggcggcggcggaggtgGCGGTGGCAATGGCGGCAATCTCCTCAACGGCAGCTCCGGCGGCTCATCCGTCGGCGGTGGCTATATGCTCCTCCCCCAAGCGGCCAGCTCCAgtggcaataataataacactgGCGGCGGTGGTCACATGTCCTCCGGTTCGGTGGGCAATGGCGGTGGCAATggtggaggcggcggcggcggcggcggaggagcTGGTGGCAACTCTGGCGGTCCCGGTAACTCGATGGGCGGAACAAGTGCCACGCCAGGACATGGCGGTGAAGTGATCGACTTTAAGCATTTGTTCGAGGAACTGTGCCCCGTTTGCGGTGACAAGGTCAGTGGCTATCACTATGGCCTGCTCACCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGGACCGTGCAGAATAAGAAGGTCTATACCTGTGTGGCGGAACGATCCTGCCACATTGACAAGACGCAGCGGAAGCGGTGTCCTTACTGCAGGTTCCAGAAGTGCCTCGAAGTCGGCATGAAATTGGAGGCTGTTCGAGCGGATCGAATGCGGGGTGGCAGGAACAAATTTGGACCGATGTACAAACGAGATCGGGCGCGGAAGCTGCAAGTGATGAGGCAACGACAGTTGGCACTCCAAGCGCTTCGCAACTCAATGGGTCCGGATATAAAGCCAACGCCGATCTCGCCGGGCTACCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATTCAAATACCTCAGGTATCCTCACTCACCCAATCGCCGGACTCGTCGCCCAGTCCCATTGCCATTGCGCTGGGACAGGTGAATGCCAGCACGGGCGGTGTGATAACCACGCCCATGAATGCCGGCAACGGTGGCAGTGGCAACAGTGGCAATGGTGGGGGTCTCAATGGTCCCAATTCCGTGGGCAATGGCAATagcagcaacggcagcagcagcagtaccGGCGGCGGCAATAATAACGGCAGCAGCACGGGCAATGGAGCGTCCGCCggtggtggaggaggaggaggtggcggcggcggcggcaacaaTGCAGGCGGCGGGggaggaggcggcggcggtggcggcaatAACTCCGGAGATGGCCTGCATCGTAATGGTGGCCACGAGGCTGGAATTGGATCTCTGCAGAATACGGCCGACTCGAAATTGTGCTTTGATTCCGGCACACATCCATCGAGCACAGCCGATGCGCTTATTGAGCCATTAAGAGTCTCACCAATGATTCGTGAATTTGTGCAATCAATCGACGATCGGGAATGGCAGACGCAATTGTTTGCTTTGCTGCAAAAGCAGACCTACAACCAGGTGGAAGTGGATCTCTTCGAGCTAATGTGCAAAGTGCTCGACCAGAACTTGTTCTCGCAAGTGGACTGGGCACGGAATACGGTCTTCTTCAAGGACCTCAAGGTCGATGATCAAATGAAGCTACTGCAGCATTCGTGGTCAGACATGTTGGTCCTGGATCACCTGCATCATCGCATTCACAATGGCCTGCCCGATGAGACGCAGCTGAATAATGGTCAGGTCTTCAATCTGCTCACTGGGCTGTTGGGTGTACCACAATTGGGCGATTATTTCAACGAGCTGCAGAATAAGCTGCAGGATTTGAAATTCGATATGGGCGACTATGTCTGCATGAAATTCCTAATCCTCTTGAATCCAAATGTGCGGGGTATTGTCAACCGGAAGACTGTTTCCGAGGGACATGATAATGTGCAAGCCGCTTTGCTGGACTACACCCTCACCTGTTATCCGTCAGTTAATGACAAATTCAGTAGGCTAGTGAACATCTTACCGGAAATCCATGCCATGGCCGCACGCGGTGAGGAGCACCTATACTCCAAGCATTGTGCCGGCAGTGCACCAACCCAAACGCTGCTCATGGAGATGCTACACGCCAAGCGGAAGGTGTAG
Protein Sequence
MDTFNVPSMLAESNGTNYATEATSNHHHLQQQQQQHQSLLLPHHHKDQMLAAGSTPMLPFYSHLQMQQKDATGTPTAAAAPAASAADNFSTLQAIDASLDGGISLSGLCERFFVASPNPHSNSNNMTLMGTASAAATTTATATTTTNNNNTTKNNVEAKAVRPSNSVIIESVTMPSFANILFPNHRTNHQQECIDPTLLQKNPQNNNNNNNNIVPPVEYHQLNPLRVNSSSTSGSVSTSNFLSSTTAQLLDFEVQVGKDDSHIISTTTTTATGSGSGSGSGSGSGSATSTTTTANPTRSSLHSIEELAASSCVPKVTSPNNSNNSSNASTTPQQQHSSSQQQQQQQHHMQSGNNSGSNLSTDDESMSEGFGLEIDDNGGYQDTTSSHSQQSAGGGGGGGGGNGGNLLNGSSGGSSVGGGYMLLPQAASSSGNNNNTGGGGHMSSGSVGNGGGNGGGGGGGGGGAGGNSGGPGNSMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVITTPMNAGNGGSGNSGNGGGLNGPNSVGNGNSSNGSSSSTGGGNNNGSSTGNGASAGGGGGGGGGGGGNNAGGGGGGGGGGGNNSGDGLHRNGGHEAGIGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLTGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPNVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFSRLVNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00596709;
90% Identity
iTF_00527356;
80% Identity
iTF_00594600;