Basic Information

Insect: Drosophila seclusa
Gene Symbol: RREB1_1
Assembly: GCA_035043575.1
Location: JAWNMX010000474.1:2255-8930[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.038 2.4 8.8 0.8 1 21 263 283 263 285 0.93

2 13 0.00035 0.022 15.1 0.2 1 23 295 317 295 317 0.98

3 13 0.00026 0.017 15.5 7.2 1 23 323 345 323 345 0.98

4 13 0.92 59 4.4 1.5 2 20 573 591 573 593 0.93

5 13 0.017 1.1 9.8 0.2 1 23 737 759 737 759 0.97

6 13 1.3e-05 0.00083 19.7 0.7 1 23 769 791 769 791 0.99

7 13 0.00087 0.056 13.9 2.0 1 23 797 820 797 820 0.97

8 13 0.0031 0.2 12.2 2.0 1 23 1084 1107 1084 1107 0.95

9 13 9.1e-05 0.0058 17.0 0.3 2 23 1490 1511 1489 1511 0.97

10 13 0.15 9.7 6.8 6.3 1 23 1517 1540 1517 1540 0.97

11 13 9.8 6.3e+02 1.1 3.4 1 23 1658 1681 1658 1681 0.78

12 13 0.0089 0.57 10.7 0.5 3 23 1741 1761 1739 1761 0.96

13 13 0.0014 0.09 13.3 4.8 1 23 1767 1789 1767 1789 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.038	2.4	8.8	0.8	1	21	263	283	263	285	0.93
2	13	0.00035	0.022	15.1	0.2	1	23	295	317	295	317	0.98
3	13	0.00026	0.017	15.5	7.2	1	23	323	345	323	345	0.98
4	13	0.92	59	4.4	1.5	2	20	573	591	573	593	0.93
5	13	0.017	1.1	9.8	0.2	1	23	737	759	737	759	0.97
6	13	1.3e-05	0.00083	19.7	0.7	1	23	769	791	769	791	0.99
7	13	0.00087	0.056	13.9	2.0	1	23	797	820	797	820	0.97
8	13	0.0031	0.2	12.2	2.0	1	23	1084	1107	1084	1107	0.95
9	13	9.1e-05	0.0058	17.0	0.3	2	23	1490	1511	1489	1511	0.97
10	13	0.15	9.7	6.8	6.3	1	23	1517	1540	1517	1540	0.97
11	13	9.8	6.3e+02	1.1	3.4	1	23	1658	1681	1658	1681	0.78
12	13	0.0089	0.57	10.7	0.5	3	23	1741	1761	1739	1761	0.96
13	13	0.0014	0.09	13.3	4.8	1	23	1767	1789	1767	1789	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaacagcagcaaccacaacagcaacaatcgcacacagctgcagcaactgcagtagcagcagcagcaacacaagaGGATGCTAGGGATTTGGGATTAATGGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACACCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAATTGCGACAgccacaccagcagcagcaaagtttgCCACTCTCCGatgaggagcaacagcagcaacagcagcagcagctgttggatTCGTCAACGCAGCGACCGCGTCACAAGCAGCGGCGcagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGTAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTGTCCGAGTCTGGCTTTGTTGATGGCAGCGCCGTCAGTGGCTATCTgcttagcaacaacaacaataacaacaacaataataacaatatcaacaacaatatcagtagtagtagcagcagcagcgcagtcgctcagtcagcagcagcagcagcgtcggcaGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGTGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGCCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAGGcctcgcagcagcagcagcagcagccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcgacgccAGCAACATGCGGGCGGAGCAGGCGCAACTGGCTCGGGATCTGGATCAGCACAGTTGTTGACGACGCGAGCAGAAAGCTATGAGAGTGATGCCAGCTGTTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatcgaaccacaacaacaacaacaatagccacaaaacgaacaacaataacaacaacagcaacaataataataataataacaatgagGATGAGCTCGAGCTGGAGGATGAGCAGCTAGTATTGAGCAACAAACAGCGACGCCTCAAGGCAGccctaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCGGATGTGGACAGCGTTGAGAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATTACATTCACCGCCCCTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAactggaggagcagcagcagcagcacgaggAGGACCACgaacagcagcacaagcaggaGGAACAGGAGCACGCCGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGTTGTATCTGAAGAATAAATCGTCAGCAGCGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGATCAGCGGCAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACTAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGATAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATAGGCCATACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGACCGATGCTGATATGCTAACCGAGCTGAGCGGCTATCGCTGTCCCACACCCACGGAGCACAGCTCCTCAGCTAGCTCCTCGTCACAGTTAAAGCATATGTTGCTGGCGGAGCCGACGCCGGCCGTAAAggtgacagcaacagcagcagcaacggtggcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTTGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTGGAAAGACAcgaattgctgctgcagcagcaacaccaacagcagcagcagcaacaacagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTAtatgcaacagctgttgcgCAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCacgccgccgccaccagcaacggcagcaacagcagcagacaagtcaatgccaacaaatccagcagcagcagccggcgcaacagcagcaacaattgctgcaatgCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGTTATCGCACCGAGCGTCCCTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAATATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCTGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGACTGCGTCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagctgccgcagcaatGAGTAAtctcagccagcagcaacagttgcagcagcagcagttgcagcattcacattcacatcaCGTCCATGCGCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGTTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTTTAGctacaacaacggcaacagcaacaagcagcagcagcaacaacagttgggCAACAACACTGGCAACTCTTTGGTGATGGACGATGATGAGCCACCCAAGTTGATTATTGACGAGGATGACGAGGATGTGGAGGGAgaggacgatgaggatgaggaggaggagcaggaatTTGATGTCGATGAGGATGAGCAGGAGGATGAAGAGATGGACTTGGACGatgagcatcagcagcagccgcacgaggaggatgacgatgacgatgatgatgatattgatgatgatgctgcagcagcagcaacagaggcgtcgcagcaacaattgcagccaaCAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCTCCGAGAAACAGCCGCATACTCAAGCGGAATCCCTGGGCGGCAATAAGCCGGcggcgccaacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGATGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCTTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAACGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACgtgaactggaactggaacgggaacgggagcGGGAACAGCAACATTTGATCCAACAGTATCGCCAACAAatggccgctgctgcagcggctgcagttgccgctgtcgctgcacCAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTTCAGTGCCTCGAGCACATCAAGCAGCTGCACGCTCACGACTTCGCACTGCTCCTGGCCAAGGGGGCCATCGAAACGGATGCACAActgcagcatcaacagcagcaacagttgccaatGGCCGGTGGTGCTCCACATTCGGATGatgaggctgctgctgtcggcaCCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGCCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacacttgccagaacaacaacaacaataataacaacaacaatagcaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTGA
Protein Sequence: MLATQQQQQQQPQQQQSHTAAATAVAAAATQEDARDLGLMETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQPHQQQQSLPLSDEEQQQQQQQQLLDSSTQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNNINNNISSSSSSSAVAQSAAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQPSQQQQSTQQQQQPQSQSQQQRRQQHAGGAGATGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNSNNNNNNNNEDELELEDEQLVLSNKQRRLKAALNNNNIIRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEEQQQQHEEDHEQQHKQEEQEHAEQRECEDFFQQLYLKNKSSAALLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTDADMLTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTATAAATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQAPGFPFFGFLTPPPPATAATAADKSMPTNPAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERTASSSAVQAAAAAQAAAAAAAAMSNLSQQQQLQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNGNSNKQQQQQQLGNNTGNSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEEQEFDVDEDEQEDEEMDLDDEHQQQPHEEDDDDDDDDIDDDAAAAATEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKASEKQPHTQAESLGGNKPAAPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREQQHLIQQYRQQMAAAAAAAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQLQHQQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNTCQNNNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -