Basic Information

Insect: Drosophila sechellia
Gene Symbol: -
Assembly: GCA_004382195.1
Location: NC:16919982-16926081[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00014 0.0089 16.1 1.2 1 23 165 188 165 188 0.96

2 14 0.0014 0.091 12.9 3.1 2 23 237 259 233 259 0.90

3 14 0.0063 0.39 10.9 0.8 1 23 351 374 351 374 0.93

4 14 0.07 4.4 7.6 3.2 2 23 423 444 422 445 0.94

5 14 0.00057 0.036 14.2 0.4 1 23 515 538 515 538 0.92

6 14 1.7 1e+02 3.3 0.1 2 14 557 569 556 581 0.85

7 14 0.0011 0.07 13.2 5.6 2 23 589 610 589 611 0.95

8 14 0.0043 0.27 11.4 0.1 1 20 698 717 698 719 0.95

9 14 0.0014 0.089 12.9 0.3 1 23 751 774 751 774 0.93

10 14 0.002 0.13 12.5 1.5 2 23 824 846 823 846 0.95

11 14 0.015 0.97 9.7 1.8 1 23 942 965 942 965 0.91

12 14 0.011 0.67 10.2 1.0 1 21 1017 1037 1017 1038 0.95

13 14 0.96 60 4.0 1.1 2 23 1069 1092 1068 1093 0.82

14 14 2 1.3e+02 3.0 0.1 1 13 1111 1123 1111 1127 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00014	0.0089	16.1	1.2	1	23	165	188	165	188	0.96
2	14	0.0014	0.091	12.9	3.1	2	23	237	259	233	259	0.90
3	14	0.0063	0.39	10.9	0.8	1	23	351	374	351	374	0.93
4	14	0.07	4.4	7.6	3.2	2	23	423	444	422	445	0.94
5	14	0.00057	0.036	14.2	0.4	1	23	515	538	515	538	0.92
6	14	1.7	1e+02	3.3	0.1	2	14	557	569	556	581	0.85
7	14	0.0011	0.07	13.2	5.6	2	23	589	610	589	611	0.95
8	14	0.0043	0.27	11.4	0.1	1	20	698	717	698	719	0.95
9	14	0.0014	0.089	12.9	0.3	1	23	751	774	751	774	0.93
10	14	0.002	0.13	12.5	1.5	2	23	824	846	823	846	0.95
11	14	0.015	0.97	9.7	1.8	1	23	942	965	942	965	0.91
12	14	0.011	0.67	10.2	1.0	1	21	1017	1037	1017	1038	0.95
13	14	0.96	60	4.0	1.1	2	23	1069	1092	1068	1093	0.82
14	14	2	1.3e+02	3.0	0.1	1	13	1111	1123	1111	1127	0.81

Sequence Information

Coding Sequence: ATGGAGGGCATGGATCTGTGGACGTCGATGTTTTCGTCCGACTTCGAGGAGGGTGAGGCGGAGAGCGGGGCGGCGGAACTGGAGGAAAGCGAGCAGTACGGGAACGGCAATGATGACTTCCTAGGCGATACGGAGATCCTTGATTCAGGCGATGCCATCGATGACCTGTTGGATGCCGAAGAGGATGAaagggaggaggaggaagactACGAAAAGAACTCCAAGGAGCCAAAGCAACCAGATCCCGACGATGATGCGCTCTTTGATTTTAATATGGAACCCATTGTTGATATAGCGGAGCCACAGCATCCATCGTTGGCTCCTGCTGGACCCATGGGCCACCAAGTGCGTCCGCCAATGCAGCGACACTCATTCCCGGGAGCTGTGGGTCGACCTAGATTGGGTCCCGGTCTGTCTGTACGACCCACCACCTCGCAGATCAACGCAACGGACGAGAACGGAGTGCCAATTAACTACGAGTTGGGCGTAGTCTACATCTGCCCCGCCTGCGGTGGTGAATTCCGGCAACAGGACCACTGGAAGCGGCACATGAACCACATCCACAAATACAACACCCTGCGTGGCTTGAACTTTACGCCGCTGGACAAGCTCTATCAGCGGTGCAGGGAGTGCAACAAGCGGATTGCCATGCACAGCCGGGAGAACTTGCTTAAGCATAAGTTCACGCACCTGCCCTTCAGGTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAATACAGGCAAGATCTTATGGTTCATCTTCGCATGGTCCATTGCGATGAAGTCGTGGCCATGATGCGTGAGGGTTACAATGCGGCGGGGCGGAAGACACGGGTTCGAGAGTCTCGCACCGAGCAGCTGCTGCGGGAGAAGAGCTTCCGAGAGAATGATGACCTTGCGGAGGAATCCGATCGCATAGAGGTGAGGAATGAGCTGCTCGAACCAGATGTTGATGAGTCTGGCATCCAGGAGCAGACCGTGTCGGAAGAGGTTTCCAAGAAAAAGGCTGGCACTCGAGCAGCTGAACTGTGCGAGGATTATATACACTACATGTGTCCAGACTGCGGCACCGAATGCGACACTCACGCCCAATGGAGCCAGCACATCGAGTTCGTCCATGACTACGTCAGCCGAAGGGGACTTAATTTCCGAAGCGTGGACATGCAAATGCAATGCCTCGAGTGCAAAAAGATTGTGACTCCCAACACCATTAAATCACTTCGCGCCCACAAATTCAGCCATTTGTCGCATCCTGAGTGGCTGCGTTGTAAACTCTGCTACAAGGGTTACACGGATCATCAGGAAATAATCAGACATCTGCTGCAGCACCATCATATGGATACGCTTATTTCGGAGGAcgccgaggaggaggatggTGATGCTTCCGCAGCAATAGAGGCGGAGGATGGATGCGACGGGGACAATGGAAACGGCGAGGGAAATGGCGCCGTTTTGGACGAGGACTCGCCCTATTTTGAAGACGCACCCAGACGGGGTGGTCGCATCAGCAGCGACGACATTTTCGAGCCCCACATCGACTACCTCTGTCCGCAGTGCGGCAAAGAATTCATCGAGAAGAAGCACTGGCGCACCCACGTGGTCATGGCGCACAGCATGAACGATCTGAGCAAGCTTAATTTTGAGATGATAAACGAACGGCAGCTGAAGTGCACTGAGTGCGACAAGATCATAACCAATGCGTATGGAATCCAGAATGCCCAGCAACACAGGATCACGCATCTTCCATTCAAGGCCTACGCCAGGTGTCGCAAGTGCCACAAGTCCTACACAGACAGAAAGGGTCTCGTAAAGCATCTGGCTACCCATCATCGTGTTGGTTGGCCACGAAAGCTTTCGGGAGGATGCCCCGCTCCAATTGTTACACCCACCAAGCAGCCACGCAAACAGATAGTGACGGTAGCCAATGAAACGTACGAGATAATCTATCTGGACGACGTAGACCAAGGCGGCATGGAGGAGGATAACGACTTTGGTGAACAGATGCAGGCAGAAGAGGATGAATATCCAATtgcaccgccaccaccaccaccaccgccacaaCCAACATCTCAAGGAAATCATCAACGCTACAAGTGCGTCCACTGTGGCACACTGTTCGCTACCCAGGCGGCCGTCCGTGTTCATATTAGCGAAAAGCGGTGCAGGAAGACAGTGGTCAGAAGGCGTCGACAGCCAGTGATGAACTCTGGGGATCCATCCGTGGCCACCGTAGAACAAAATTACATCTTCTTGTGTCCATCCTGTGGATTTGAGTACAAGACTCAGTTCGAGTGGCGCCGTCACATCAACGAGGTGCACAATTTTGACAAACGTCAATATCTAAACATGCGTCAGTTGGATAAGTATCGCTATCAATGCACCCAGTGCAAGGACATTGTATGCAATTCGAAGCTGAAGGGTTTGCAGGACCATCACTTCCGCCATCTGCCCTACAGACTGTACCTCAAGTGCCTGATCTGTGGCACCTGCTACAATCACAAGCCGAATATAGCTGCACATTTGAGAGCCCGTCACAGCATTTTTGATAGGGAGACGCCGGCGATGATCACAAAACCTAAACAAGTGCTTGGGCGTTATAAGGATAACAGTAGGGAGAACCCTAAATTGCCCTCTCCACCACCGGCTCGAGCACTGGCACCAGCACCGCCCTCACCACCTGCATGTTCCTCTTCTGCTTCCACTGCGAGTAGTCGTTCCCTAAAACCACAGCCTGGCGGATTGCCAGCCCGACCCGCTGGTCTCAACACGCTGGAGGACAGCATCTCGTACCACAATGCCGTGGACCTGGACTTCATCACGTACTTTTGTCCCAAGTGCAATCAGAACTTTGACTCTCATGCTTTCTGGCGCAAACATATTGTGGAGCAGCACAACTTTAACAGCCGTGAGGGCCTCAACTTTCGGCAGATCGACAACCATCACTACCTGTGCCTGGAGTGCTACAAACGGGTGACCGTGACGCACACCAAGGGAGCCATCGGGCAGCTACAGTCGCACAAGTTCCGCCACCTGCCCCACAGATCCTTCAAGTGCTTGACTTGCGGCGGTGAGTTTGTGCgcaagcaaatgtttttcAAGCACCTGAACCGCGACACTAACCGCTGTGACAATCGTCCGCACCGAGAATTCGATGACGATGAGCCCGACCAGGATACGCTATTGAGCTCCATTTACCATCTAACGTGCCCGCAATGCGGTGACAACTTTAAAACTAACAATAAAAAGGAATGGCGGGAGCACATCAACGACCACCATGGCTTGACCAAGCTGGAGCTTTTGCACATGACCAAGGTGGGTGAGGATGTCTACCGCTGCCAGGACTGTGATGAGGAGCTGGAGACGAATCGACAGTGGGTGCTACAGTTCCATCGATTCCAGCACCTGCCCCACGCGGCCTACATCCGTTGCAAACTATGCAAGCAGAGCAGTGAGGACGATGCTGCTGCGGTGGGTGAGTTGCACAGCCTCCGTGAGCTGCAACAGCACATTCGTAAGCACCATCCGGGCCTGGGGGATGCCGAGATGATATCGCTCATCGAGCAGATAATTCAGGACgagaaggagcaggaggagggcACGAAGCAGACCAATGATGATGAAAACCCTACTGGTCAGGACTCAGGACCGTATATGCCGTTGCCGCCACATCTTTTGGACGATGATGGCGACGTGGAATTCGAAGATCAGTATCTGCTCGGCTAG
Protein Sequence: MEGMDLWTSMFSSDFEEGEAESGAAELEESEQYGNGNDDFLGDTEILDSGDAIDDLLDAEEDEREEEEDYEKNSKEPKQPDPDDDALFDFNMEPIVDIAEPQHPSLAPAGPMGHQVRPPMQRHSFPGAVGRPRLGPGLSVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNHIHKYNTLRGLNFTPLDKLYQRCRECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQLLREKSFRENDDLAEESDRIEVRNELLEPDVDESGIQEQTVSEEVSKKKAGTRAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTDHQEIIRHLLQHHHMDTLISEDAEEEDGDASAAIEAEDGCDGDNGNGEGNGAVLDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATHHRVGWPRKLSGGCPAPIVTPTKQPRKQIVTVANETYEIIYLDDVDQGGMEEDNDFGEQMQAEEDEYPIAPPPPPPPPQPTSQGNHQRYKCVHCGTLFATQAAVRVHISEKRCRKTVVRRRRQPVMNSGDPSVATVEQNYIFLCPSCGFEYKTQFEWRRHINEVHNFDKRQYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHSIFDRETPAMITKPKQVLGRYKDNSRENPKLPSPPPARALAPAPPSPPACSSSASTASSRSLKPQPGGLPARPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCGGEFVRKQMFFKHLNRDTNRCDNRPHREFDDDEPDQDTLLSSIYHLTCPQCGDNFKTNNKKEWREHINDHHGLTKLELLHMTKVGEDVYRCQDCDEELETNRQWVLQFHRFQHLPHAAYIRCKLCKQSSEDDAAAVGELHSLRELQQHIRKHHPGLGDAEMISLIEQIIQDEKEQEEGTKQTNDDENPTGQDSGPYMPLPPHLLDDDGDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00592022;
90% Identity: iTF_00596968;
80% Identity: -