Dsec010034.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila sechellia
Gene Symbol
RREB1
Assembly
GCA_004382195.1
Location
NC:4383610-4393764[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.029 1.8 8.8 0.8 1 21 246 266 246 268 0.93
2 13 0.00027 0.017 15.2 0.2 1 23 278 300 278 300 0.98
3 13 6.5e-05 0.0041 17.1 7.3 1 23 306 328 306 328 0.98
4 13 1.2 75 3.7 3.8 2 19 538 555 538 557 0.97
5 13 0.0067 0.42 10.8 0.1 1 23 701 723 701 723 0.97
6 13 9.9e-06 0.00062 19.7 0.7 1 23 733 755 733 755 0.99
7 13 0.00067 0.042 14.0 2.0 1 23 761 784 761 784 0.97
8 13 0.0024 0.15 12.2 2.0 1 23 1049 1072 1049 1072 0.95
9 13 6.9e-05 0.0044 17.0 0.3 2 23 1442 1463 1441 1463 0.97
10 13 0.12 7.3 6.9 6.3 1 23 1469 1492 1469 1492 0.97
11 13 6.2 3.9e+02 1.5 2.0 1 23 1612 1635 1612 1635 0.83
12 13 0.0068 0.43 10.8 0.5 3 23 1692 1712 1690 1712 0.96
13 13 0.0011 0.071 13.2 4.8 1 23 1718 1740 1718 1740 0.99

Sequence Information

Coding Sequence
ATGCTCGCCGCACAGCAAcagcacaacaacagcacagTGGAATCGGAAATGGAGCGCCAGCGACGTGACTCCACCACATCGGAGTCCTCGCTGGAGCATCTGGATCTGGGCCGTACGCCCAAAAAACTGGGCGGCAACAGTGGCTCTACACAGACCACATCCACGCCACATGAGCTGACTACGGTGACGTCGTCGCGCAAGCGTAAGCTTCGCCATTTGCAATTGAatcaccatcagcagcagcagcatcatcagcaGTCGGATCTGCTGAGTGATGAGGacgaggcggaggaggatgaggacgaggaggatgaCGACCAGGTGTCCGCCTTGGGTTCAAGGAATGTGGGACGGCACAAGCAGCGTCGCAGTGGTGGCGCCACCACACAGGCATCCATTGTGGTGGACTACAGCAGTGGCGATGCCAGTTCGCTGCGCAAGAAATTTCGTCTGAATCGTTCGGCGGCCAGTCTCTCGGAATCGGGATTCGTGGACGCCAGCAGCACCACTGGCCACAGTGGCTATCTGGGTAACAGTAGCAGCGCAACGAACACTACTGCCACCAGTGGCATTGGTGCTGGCGCAGTGGCTCCCTCTCCAGTCGGCGGAGCAGCGACCAACGCAgcctccagcagcagcggcagcagcagtggcgGATCCGGTGGCTCCTCGCCCCAGGGACTGTGCCTCTCCAGCGGCGAATCGGGCATCGGAGCCGGCGACGAGCATATGAAATACCTTTGCCCCATCTGTGAGGTTGTCTCGGCCACGCCGCACGAGTTCACCAACCACATCCGGTGCCACAATTACGCCAATGGCGATACGGAGAACTTCACCTGCCGCATTTGCTCCAAGGTGCTATCCTCGGCTTCATCCCTGGACAGACACGTGCTGGTTCACACGGGCGAGCGTCCCTTCAACTGCCGCTACTGCCACCTGACGTTCACCACCAATGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCATCAAGTTGCGCAGTCGCagtcacagcagcagcagtcgcagcagcagcagtcacagcagcagcgccgtcagcagcagcaacatcagccgtcgcagcagcagcagaatccCGCCCAGCAGCAATTGGTGACCAACACGTTATCCGGCCGAGCGGAGAGCTACGAAAGCGATGTCAGCTGCTCCACGGACGTGTCCAGTGGACATAGTcacagtcgcagcagcagttccctcaacaacaataacaacaactcGCACAAGGCTAACAACAACCTGAAGGACTTGGAGGAGCTGGAAGTTTCGGCTGAGGATCAGGATACGGAGAACAAGCAGCGTCGACTGAAGACCAccatcaacaacaacatcatTGAGCgtgagcagcaggaggatATGGATGATGAGGAGGCCGACGATGCGGATGTGGCCATGCTGACCAGCACTCCCGATGTCGCTACTCTTTTGGCCGGAGCCAGTGCATCCGGCGCCGCTTCGCGTTCCCCCACCCCATCGCCATCCGCCTCGCCCGCTTTGCTCCTGAGCTGTCCCGCCTGCGGAGCCTCCGATTTCGAAACCCTGCCCGCTCTCTGCGTCCATTTGGATGCAATGCACTCAGACATACCCGCCAAGTGTCGGGACTGCGAGGTGATCTTTGCCACCCATCGTCAGTTGCAGGCGCACTGTTGTCGCTTACCCAACGCTCTGGGCGGTGGCTTACCTCCGCTCCTCGGAGCCAGCAGTTCGCCATTGCACAACGAGGAGCCGGAGGATGAGGAGCACGGCGACGATGAGGATCTCGAGCAGAAGGAGAGGTTAGCGAGTCAAAGCGAGGACTTTTTCCATCAGTTGTATCTGAAGCAGAAAACAGCAAATGGATGCGGGGCCATCTCACATCCGCCATCGCCGATCAAACACGAGCCGGCGGACACCAAGGATCTGGCCGATATCCAGAGCATCCTGAACATGACCAGCTCTAGTTCCAGTTTCCTGCGCAACTTTGAGCAGTCGGTGAACACGCCCAACTCGAGTCAGTACAGCCTGGACGGTAGGgatcaggaggaggaggcacAGGACGCGTTCACCTCGGAGTTCCGTCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTGTGCACGGCCGTTTTCCCGAACCTTCGTGCCCTCAAGGGTCACAATCGGGTGCATTTGGGCGCAGTGGGTCCAGCCGGACCCTTTCGCTGCAACATGTGTCCCTACGCCGTTTGCGACAAGGCCGCCTTGGTGCGCCACATGCGCACCCACAACGGAGATCGTCCGTACGAGTGCGCCGTGTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGCCATCTGAGGAACCGCCATGGGAAGACCAGTCGCGAGGAGGTGAAGCGAGCCATTGTCTATCATCCGGCGGAGGATGCTGGCTGTGAGGACGGCAAATCGCGTCTGGGTGAAGATCTGGCGGATATGAGTTTCCGTTCGATCAGTCCCacgccaccgcctcctccgGTAAATGAGAGCAGCTCCCAGTTGAAGCACATGCTTCTCGGCGAGAGTCACCTGGCTCCTGTTACCCAACAGCCGCCTTTGAAGATCCAGGTGAAGAGCCTCGACCAACTAGTGGACAAGAAGCCATCTGCACCAGCtccccagcagcaacagcagcagcaggagaagAGTGGAGCTCCCCTAGACTTCAGCATGGATGTTTTGGATCTCAGCAAGAAGCCAACTGGCGGAGCATCGCTGACACCGACGGTCACTCGCACACCGACGCCCGCTGCAGTAGCTCCAGTGGCGCCTGGCGGCGTTGGAACTCCTGACCTGGCCGCCGCCAttgagcagcaacagctgctgctggcccaGCAGCAACTCTTTGGAGCTGGCGGCGAATACATGCAGCAGATATTCCGCAGTCTCATGTTTCAGTCCCAGACGACGGGATTCTCGTTCTTTCCCTTCAtggcaccaccaccgccacaaGCAAATCCGGAGAAGCCACCGCTGGTTAGTCCACCAAACCGCCTCAATCCCATGCCCGTGGGCGTTGGAGTCGGCGTGCCAGTGCCACCTGGTGGTCCCGTTAAGATGGTCATCAAGAATGGAGTCCTAATGCCCAAGCAGAAACAACGACGCTATCGCACCGAGCGACCCTTTGCCTGTGAGCACTGCTCGGCGAGATTCACGCTGCGTTCGAACATGGAGCGCCATGTGAAGCAGCAGCATCCGCAGTTCTACGCCCAACGGCAGAGGAGTGGCCACCATGTGATGCGGGGCAGGGGTGCCTCCAATGtggccgctgctgccgccgctgctgccgccgccgctgcaaCAGTCATGGGTCAGGTGCCGGTTGGCGGACCAGGATCCTCCGGATCGGGCTCCAATCACCATCATGGCCACGGCCATGGTTCCCATGGTTATGCTCCCATTTCGGAGCAGGTCAAGTGCGCCATTCTGGCGCAGCACTTGAAGGCTCACAAGAACACCGATCTGTTGCAGCAGGCTTTGGCCCACGGCTCCAGCAGTGTGGCCGGCAATCCTCTCCTGCACTTTGGCTACCCACTGACCAACCCCAGCCCCCTGAACAATGGTGCCAGCCAGGGCAATGGCCAGGCCACCGCCATGGATGACGATGAGCCCAAGTTGATTATTGACGAGGATGAAAACGAGCATGATCATGAGGTGGAAGCAGAGGACGTGGATGACTTCGAAGAGGATGAAGACGAGGAGGAGATGGATGAGCCGGAAGATGAGCCGGAACTGATTCTAGATGATCAGCCGGCCGAAAAGGAAGCCgaagaggagcaggagctgccCAAGCCGCTAGAGCAATTGGGTATCAAAGAAGCCGCGCAAAAAATGGCCGAAACCATTTTGGAGCAGGCCATCAAGGCGGGCAAGCCGTCGAGTCCACCACCCACCAAGGAGAATGCCCCGCCCGCCAATCCAACCGTGGCCACAACCATGCAGGAGCCAGCCACTGCTGCGCCCAGTACTAATCCCAGCAGCTTAAAAACGATGATCGCTCAAGCCGAATCTGTGGGAAAATCCCTCAAAGAAGTGGCCAGTTCGCCGTTCAAGGATGAGTCCCAGGACCTGGTTCCAGTGGCCAAGCTGGTGGACAATGCCACCAGCCAGAACATGGGCTTCAACAGCTATTTCCGGCCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAAGAGGGCCTGGTGGCCTCCGGGAGCGCCAGTGagagcaacaacagcggcacCGAGGACGTCACCAGCAGCAGTTCCAGCAGTGAGCCCAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAACCGTGTCTCCTGTCCGTACTGCCAGCGCATGTTCCCATGGAGCAGCTCGCTGCGGAGGCACATCCTCACCCACACTGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGTTGTTCACCACCAAGAGCAACTGCGATCGCCATCTCTTGCGCAAGCACGGCAATGTGGAGTCGGCCATGTCCGTGTATGTGCCCACTGAGGATGTGAGTGAACCGATACCAGTGCCCAAGTCCGTCGAGGAGAtcgagctggaggagcagcgACGGCGGCAGGAGGCGGAGCGCGAGAAggaactggagctggagcgCGAACGGGAGTtggagcgggagcgggagcTGGAAAGGGAGCGTCAGctggagaaggagaaggaacGCGAGCGCCAGCAGCTCATCCAAAAGCTGGCAGCTCAAATGAATGCTGCTGCCGTCGTTGCTGCAGCCTCAGCGGTAAATGGTAGCGCATCTGGAGGACCCCATGGACCCATTGCAGATGCCTTGGCTGGCGGAGATCTGCCCTACAAGTGCCACCTGTGCGAGGGTTCCTTTGCCGAGCGTCTGCAGTGCCTGGAGCATATCAAGCAAGCCCATGCCCACGAGTATGCCCTGCTCCTGGCCAAGGGAGCCATTGAAACCGATTCGCTGGAGGCCAATCCTCACCAGCAGCCGTCGCAGCAGGCCGTGCACTCCGATGACGAGGCTCCGAATGGTGGCGGTAACCGGGGCAAGTATCCCGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGTGTGCGTCGCTTCTGGTCTACCGAGGATCTGCGTCGCCACATGCGCACCCATTCGGGCGAGCGGCCATTCCAGTGTGATATCTGCCTCAGGAAGTTCACACTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGTAGGGCCCACAATGGGGATACACCGGGATCCGACTGCTCCGACGACGAGCAGGTGAGCAGCCCGCCCAGCACTCCGCTTCCCACCCAGCCGACCagcgccaacaacaacaatagctgtcacaataacaataataataccaacaacaataacaacaacaacggcagctCCAAGCTGGGACTAAAGCTCCACGACCTGCTGGACAAGGCGAGCGAATGGCGGGCCAGTCGCCTGGGCGAGCACAAGGAGAACATGGGCGAGGCCACGCCCTCGGGAGCAGCGGTCGCTGGTTCGGATCTGATTGGCAATCTATTGGGCATCAGTGACCAGGGCATTCTCAACAAGTTGCTCTCCTCCGCCGACGAGGCGGCCAAACTTCTGGGTGTGGACAACAAGTGA
Protein Sequence
MLAAQQQHNNSTVESEMERQRRDSTTSESSLEHLDLGRTPKKLGGNSGSTQTTSTPHELTTVTSSRKRKLRHLQLNHHQQQQHHQQSDLLSDEDEAEEDEDEEDDDQVSALGSRNVGRHKQRRSGGATTQASIVVDYSSGDASSLRKKFRLNRSAASLSESGFVDASSTTGHSGYLGNSSSATNTTATSGIGAGAVAPSPVGGAATNAASSSSGSSSGGSGGSSPQGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQVAQSQSQQQQSQQQQSQQQRRQQQQHQPSQQQQNPAQQQLVTNTLSGRAESYESDVSCSTDVSSGHSHSRSSSSLNNNNNNSHKANNNLKDLEELEVSAEDQDTENKQRRLKTTINNNIIEREQQEDMDDEEADDADVAMLTSTPDVATLLAGASASGAASRSPTPSPSASPALLLSCPACGASDFETLPALCVHLDAMHSDIPAKCRDCEVIFATHRQLQAHCCRLPNALGGGLPPLLGASSSPLHNEEPEDEEHGDDEDLEQKERLASQSEDFFHQLYLKQKTANGCGAISHPPSPIKHEPADTKDLADIQSILNMTSSSSSFLRNFEQSVNTPNSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDGKSRLGEDLADMSFRSISPTPPPPPVNESSSQLKHMLLGESHLAPVTQQPPLKIQVKSLDQLVDKKPSAPAPQQQQQQQEKSGAPLDFSMDVLDLSKKPTGGASLTPTVTRTPTPAAVAPVAPGGVGTPDLAAAIEQQQLLLAQQQLFGAGGEYMQQIFRSLMFQSQTTGFSFFPFMAPPPPQANPEKPPLVSPPNRLNPMPVGVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNVAAAAAAAAAAAATVMGQVPVGGPGSSGSGSNHHHGHGHGSHGYAPISEQVKCAILAQHLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLTNPSPLNNGASQGNGQATAMDDDEPKLIIDEDENEHDHEVEAEDVDDFEEDEDEEEMDEPEDEPELILDDQPAEKEAEEEQELPKPLEQLGIKEAAQKMAETILEQAIKAGKPSSPPPTKENAPPANPTVATTMQEPATAAPSTNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMGFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAEREKELELERERELERERELERERQLEKEKERERQQLIQKLAAQMNAAAVVAAASAVNGSASGGPHGPIADALAGGDLPYKCHLCEGSFAERLQCLEHIKQAHAHEYALLLAKGAIETDSLEANPHQQPSQQAVHSDDEAPNGGGNRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQVSSPPSTPLPTQPTSANNNNSCHNNNNNTNNNNNNNGSSKLGLKLHDLLDKASEWRASRLGEHKENMGEATPSGAAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00605068;
90% Identity
-
80% Identity
-