Basic Information

Insect: Drosophila sechellia
Gene Symbol: hang
Assembly: GCA_004382195.1
Location: NC:16519332-16536044[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.25 16 5.9 1.0 3 23 322 343 321 343 0.93

2 19 0.31 20 5.5 3.2 3 22 451 470 449 470 0.89

3 19 0.00053 0.034 14.3 3.3 1 22 583 604 583 606 0.90

4 19 0.061 3.9 7.8 0.1 2 21 618 637 617 638 0.93

5 19 0.00062 0.039 14.1 0.2 2 23 773 795 772 795 0.95

6 19 0.0018 0.11 12.6 0.1 1 23 803 826 803 826 0.96

7 19 1.4e-05 0.00091 19.2 0.1 2 23 911 932 910 932 0.97

8 19 0.00025 0.016 15.3 2.9 2 23 1014 1036 1013 1036 0.97

9 19 0.02 1.3 9.3 0.2 2 23 1045 1067 1044 1067 0.95

10 19 8.3e-05 0.0052 16.8 0.2 1 23 1080 1103 1080 1103 0.97

11 19 0.00011 0.007 16.4 1.1 1 23 1156 1178 1156 1178 0.99

12 19 0.0017 0.11 12.7 0.9 1 23 1186 1209 1186 1209 0.96

13 19 7.4 4.7e+02 1.2 0.2 2 13 1217 1228 1217 1230 0.85

14 19 2.9e-05 0.0018 18.3 1.4 3 23 1322 1342 1321 1342 0.98

15 19 0.0045 0.28 11.4 0.1 1 23 1377 1399 1377 1399 0.97

16 19 0.00053 0.033 14.3 0.6 2 23 1478 1500 1477 1500 0.93

17 19 1.5 97 3.4 0.1 2 20 1520 1538 1519 1540 0.91

18 19 0.0059 0.37 11.0 0.4 3 23 1555 1575 1555 1575 0.98

19 19 9e-05 0.0057 16.7 2.1 1 23 1870 1892 1870 1892 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.25	16	5.9	1.0	3	23	322	343	321	343	0.93
2	19	0.31	20	5.5	3.2	3	22	451	470	449	470	0.89
3	19	0.00053	0.034	14.3	3.3	1	22	583	604	583	606	0.90
4	19	0.061	3.9	7.8	0.1	2	21	618	637	617	638	0.93
5	19	0.00062	0.039	14.1	0.2	2	23	773	795	772	795	0.95
6	19	0.0018	0.11	12.6	0.1	1	23	803	826	803	826	0.96
7	19	1.4e-05	0.00091	19.2	0.1	2	23	911	932	910	932	0.97
8	19	0.00025	0.016	15.3	2.9	2	23	1014	1036	1013	1036	0.97
9	19	0.02	1.3	9.3	0.2	2	23	1045	1067	1044	1067	0.95
10	19	8.3e-05	0.0052	16.8	0.2	1	23	1080	1103	1080	1103	0.97
11	19	0.00011	0.007	16.4	1.1	1	23	1156	1178	1156	1178	0.99
12	19	0.0017	0.11	12.7	0.9	1	23	1186	1209	1186	1209	0.96
13	19	7.4	4.7e+02	1.2	0.2	2	13	1217	1228	1217	1230	0.85
14	19	2.9e-05	0.0018	18.3	1.4	3	23	1322	1342	1321	1342	0.98
15	19	0.0045	0.28	11.4	0.1	1	23	1377	1399	1377	1399	0.97
16	19	0.00053	0.033	14.3	0.6	2	23	1478	1500	1477	1500	0.93
17	19	1.5	97	3.4	0.1	2	20	1520	1538	1519	1540	0.91
18	19	0.0059	0.37	11.0	0.4	3	23	1555	1575	1555	1575	0.98
19	19	9e-05	0.0057	16.7	2.1	1	23	1870	1892	1870	1892	0.98

Sequence Information

Coding Sequence: ATGTGCGACGCTGCGGCGGCaacagcgacaacaacaacagcagtagcagcagccgtcgcaacaacaacagcatcgGTAGCATTGGAGGCCACAGCGACACAGCCTGGaacgacaacgacgacgacgGCGGTAGCCACTGCGTCAGCGGGAACCACATCCCCTGAAGCGGTCAttccaacagcagcaatagcaacaTCGGCGAAACACAGCAACAGCGAACGGTCGGCGCGACAAAACTGCTGTCGCCTGTGCATCGCCCCACAAACCGAATGCATCTCGATCATCAATAGCTATGCGGCGGACAAGGAGCCGCTGTCCACCAAGATCCTCAACTGCGTCGGCATCAAGGTTACACCGCAGGATCGGCTGTCGCAGCAAATTTGCCACGCCTGCATCAGTTACCTGAACTCATGGCAGAGCTTCAAGAACCGGTGCTTCAGCTCGCAGGCGAAGCAGCGCCAGTGGCTGGATAACAACAAGAGCAAGCTCCTCAACTACCTGGACCTGAACAGTGCCGAGAATGGGGGAGGAGGCTTCTTCGATCAGCATctgcatcagcaacagcaacagcaacaccaccaGAACTTGGAGAATGAGCTCGAagcggagaaggagaaggcGACGCCAACGGCCGCATCGACAGCCGCCAACATATTGGACGGCATACACTCGCTGAAGAAACGCAAATCCCTAACAGTCTATCCACTGCCTGCGATGCCCATCAAAGATGAGCCGATTGATACGGATGACGACTACCAGATGAAGTCCATAGACGAGTCCGATGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCGCTGACGGCCTCGGATTACGACTACACTGCGCAGCATGGCGTGAATGCCTCGTCCGTGGCTGCCTCGCTGCCGCCGAATGCGGTGGCCAATGTGGCAGCCGCCGGGGACTCCAAGGTGGCCAGCTGCAGGGCCTGCAGCCTGCAGTTCTCTACCCGGGCCAACGCCCGTCGCCACGAAAGGAATCTGCACCCAAACCTGTTCCAGTTGTCCACAGACTCCCCCCACAACACACCCATCACAAAGCCGACGCCCGCTTTGGCTGCCGCCTTGGAAATCCAACGGGCAGCGGCCGCGGCGGCCACCGCTGAGGCAAATCGGGCAGCGGGCGCCGCTGGCGGGAATATCTCCACGCAAAAGTATCGCCAGGTGGTGATGAACACGTTCATTAAGTGCGAGGGCGGCGGCTATGACTACGATAATCCCGAACAGTACCGACCACTGCTCACCCGCGACAAAGTGGAGTTCATTGAGCAGAACGACGAGTTCCTCGAGCAATACCAGACGATGACCTGCCGATGTTGCAACAAGTACTTCAGCACGTACAAGAACTTCATGGCGCACGTTCGCAAGAAGTATCCGCAGCTGCCGCGCAACCTATGCTTCAATTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCGCATCTGAAGAAGCGGAATTGCATAAATCTCTTTAGAGTCTTGAATGCGCTGCGTGGGAAAACAACGACAGTGGTTGTGCCCATTGCAGATGATGCGGCTGACGATGGAGCAACAGGAGCTGTTCCAGTTGCCGATGCCGGAGCAGGAGTGATGGCCATGAATAGTCCCACAGTGACAGCCAGCGGAGAAGTTGTTACACCCGGCGGCGGCCCCGAACGCCCAGAGAAACTGCGTGCCAAGGAACTGCTGGTCAACAAACTGTATGAGTGCAAGCTCTGTCCCAAGGGATTCCGCACCAAGCACGAGTTCCGCACGCATGTCTACGACAAACACGCAGATGTCCAGCGCAAGGATAACAACTCGATACAGTGCAGCTTCTGCGGACTGGACTTTGCCGATCCCGTGGACAGACGGCGGCACTACAACAACATGGACTGCATTGTTCGGCTGCGCTGCATGACGTGCGATGCCAAGCTGGAAACGCACCAGCGTTTCCTCGATCATGTCTACCAGGATCACTTGGGCGGCGTGGGTGGTGGCGTGGTCAGCGACAATGCCTCCACCACTGGCAGCGGCATGGCCAGGAGCAACAGCATGGAACACTCGCCGGGCAAGAGGAGCCTGCTCGGCGCCCTAGGCGTTGGTTCCTCGGCGGAGGAGTCGCGAAGCAGCAGTGCGGCTCCGCCGCTGACCTCTACACCAAAACTGGCGGGCGGTAATCAGGTGGGTGGCGGTGGATCGACCAGCGCTTCTGCCGCCGCAGCCGCTCAGAGCTCGGCGAATCGCGATGCATCCGCACCCAAATCCCAGTACTTCTCCCGCATGCCGCAGGTTTGCCCCATTTGCGGCCAGCAgtacaacaactacaacaatgTGCTGCGCCACATGGAATCGAAGCATCCGAACAAACTGCCAGAGACATACAAGTGCGTGCGCTGCGGACTGGGCTATCCCCGGATCTCCTACCTGCGGGAGCACATGATCAATGTGCACGGAGTGGACAAGAATCGTCACTCTGGCGGCTTCGAATACATCGTGAATGCGGATGCCGTGAAGTTGGCGGACGGAAGTACGCCGAACGTCTACACGGGTCGCTACGATTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACACTCGATGATGACGAGGAGGAGCCTGGCAGCGTGGCCAAGAAGATGCGCCTGGatgacagcagcaacaacagcagcctgGTGGGCGTGGCTAGCCAGCAGAAGGAGTGCCCCATCTGCAATGCGGTGTTCAGCAACAACATTGGCCTGTCCAATCACATGCGCTCCCACTATACAGCCTCGAATGCAGTGAATGCAGCCTTGGCGGCTGCCAATCGAATGACACCCAAATCGCTAACGATTACCGCAACGCCAGCAACGGATTCGGAGTTCGGAGTTGGCGGAACAATGTCCGAGTCGGCTCCAGCAACGCCTGCCAATGTGCCACCGGCAATGGCCAATCAAACGCCCCAGGAGCAGGCAGTTTTTCGCCGGAGCCTTGACCAGGCAGCCGATCGACGCTTCCGGCGAATGCGCTGCCGCATCTGCCAGCGTCGCTTCAGTTCGAAGAAGTCCTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAATGCAAGCTGTGTAACGCAGAGTTTGCTTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGAAGGGCCATTAAGGATGAAATGATTATCAAGCAGTTCGAGTGTGAGGTTTGCTCGATTGTCTATAGTTCAGAGTcggagctgcagcagcacaAACGCAGTGTTCACAAGCTGACATCCGCCTCCGCTTCCACATCGGCGTCCACGTCCTCTAAGATTGACGACGACTGTCTAATGGATGAGGGCAAACCGACATCATCGGATCTAGCTGATCTCTCCACCCTCGCGGCGGGTGGATCCACTGCATCTGCTCCACTGTACTGGTACCAGTGCAAGTACTGTCCATCAAACTTTAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTTGACTCGAACGATTATTCCTGCAAAGATTGCGGAAATGTCTACAGCGGACGCAAGAGTCTATGGGTTCATCGTTATAAGAAGCATCCGCAAGTGCCCAACCCAGCTGAGTGCTCGCTGTGCCGCAAGGTCTTCTTCGACCGCCAGATGCATGACAACCACACGCCCACCTGCAACCGCAAGCCGATCACCTCGACCGGTGCCCACCAGGAGCAGGATGGACAGCTGCATTCCCACCACACGACCAAAAGAACAATTTTCCGGCATAAGACcggcgatgacgatgacgaggaggatgacgatgagcagcagcaactggagGAGAGGGCCAATAGCGATGGCAATGGCACCACTGTGAGAGTGGCGTCGGGCAGTACTGCAGCTGCGGGCACGTCACTGAAGATCCGCATTCCGGAGGTGGCGTGCACCATTTGCGGCGCTCGCTTCACCGACCAGGAGCACTTTAGCAAGCACATCCAGAAGCACGAGCAAGAGCTGTACGTGGACAATCCGCTGGCGGCGATGTTCGATGATGGGCCGGCGGATGCCGGTCAGTTCCAGGTGGAGCGGCAGAATGAGAACGGGGAATACGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATCGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGACCAACAACAATCAcacaaccaacaacaacaacaactcgaTGCACCTCCGCGAGCTGCATGCGGTGGGCCTGATGcccaaccagcagcagcagagccTCAACAACTCGTGCAACAGCAGCAtgaaccacaacaacaacagcagcagcaaccgcagCAAGTCGATGAAGCGGAAACGTGAGCTGAAGTGCGAATACTGCGCCTCCACCTTCATCAGCAATAACAATCTGCGTCGCCACATGTACGAGCTGCACAAACACGAGGTAAGCAATCTGCCCGAGCCGCCGGTGATTGTGGTGGACGATCACCTCACCTGCCGTCGCTGTCAGTTGAAGTTCGACACAAAGGAGCTGTGGATCGAGCACAAGCTGGCCGATGCGAAGGTGGTGCGACCTTTCTGCCCCTTCCAGTGGGGCTGTGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTGATGAACCATATTAACAACCATTTGAAGGAGGATGTCATAGTGCCAGTGGCCACTAAGGCGGCCATTGAGAGAACAGCGGCCATGGAATCAGCGGCAGCAGATGCGAATGCAGCGGCGACACTATCAGCATTGGGCGAAGGAGCCGAAACTGAAGATCAGTTTGCAGAGAAGGGTGAGGCTGCAGgggcaacaacagcagataaGTTGGCGAATCCCGACGAAGAGGATAGCGATGATTTGGATGAGGATAGCTCGGGCGACGACGATGATAGTTCGGGCACGGgagatgatgacgatgacgacgacacCGACGATGATGAGGATGGCGAGGGTGAAGATGAGGACGAGGAGGGAGATGGTGGCGAAGGCGAGGACGAAGAAGGTGTCCAGCCAGCCGCTCAACTTTTGCCGCAGCAGCTACACAAAGCGGATCTTAATCAGGACGACGATGATCTCGTCGAGGAGGTCATCAGCtccgatgacgacgacgacgatgatggaGAGGTGGAAagcgacgatgacgacgaagatgatgatgatgaggaggACGATGTGGAGGAGCCGGAGCCAGTGGGATTGGCGGTGCGACCGCTTATGAATGGCAAATCAAAGATGCCGCCGCTGATAGTGGCCAGTTCGGATGATGAAGACGATGGTGTGATGCCCATAGGGGACATTATCGAAGAGGAGTTCGATGAGGATGCCGATCCAGATCCGGAGGATGCCATTGAGGAGGTAGACGAAGATGATTTAGATGAGGGGGATGTGGAGGACGAGCCGAATGTGGTGTCGACGGCCTCCTTCTCGGAGAGCGAGTCCAGCACAACGACCACGTCcaattcgcattcgcattcaaCGGGTGAGCGGCGTAAGAAGGCCGTCGATCAGTTGAATGATCCCGGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTCCAGAGCCACATCAAAAGCCATATCCTCAATGGGCCAAAGCTCTCGACagcgtcagcagcagcagcagcagcagcagcagccgccgccaCAGCAAGCAGCAAGGCAACAGCATTACTAACGGCCGCAAAGGCGAAGCCTGACTCCAAGTCAGCGGTGCTGgccaacaataataacagcaAGACAAGCAGCAAGACTGTGGCAGCAGCTGCGACACATTGA
Protein Sequence: MCDAAAATATTTTAVAAAVATTTASVALEATATQPGTTTTTTAVATASAGTTSPEAVIPTAAIATSAKHSNSERSARQNCCRLCIAPQTECISIINSYAADKEPLSTKILNCVGIKVTPQDRLSQQICHACISYLNSWQSFKNRCFSSQAKQRQWLDNNKSKLLNYLDLNSAENGGGGFFDQHLHQQQQQQHHQNLENELEAEKEKATPTAASTAANILDGIHSLKKRKSLTVYPLPAMPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDVPLTASDYDYTAQHGVNASSVAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAAAATAEANRAAGAAGGNISTQKYRQVVMNTFIKCEGGGYDYDNPEQYRPLLTRDKVEFIEQNDEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPQLPRNLCFNCLKMNDSKALFISHLKKRNCINLFRVLNALRGKTTTVVVPIADDAADDGATGAVPVADAGAGVMAMNSPTVTASGEVVTPGGGPERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGVVSDNASTTGSGMARSNSMEHSPGKRSLLGALGVGSSAEESRSSSAAPPLTSTPKLAGGNQVGGGGSTSASAAAAAQSSANRDASAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEPGSVAKKMRLDDSSNNSSLVGVASQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITATPATDSEFGVGGTMSESAPATPANVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSESELQQHKRSVHKLTSASASTSASTSSKIDDDCLMDEGKPTSSDLADLSTLAAGGSTASAPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPNPAECSLCRKVFFDRQMHDNHTPTCNRKPITSTGAHQEQDGQLHSHHTTKRTIFRHKTGDDDDEEDDDEQQQLEERANSDGNGTTVRVASGSTAAAGTSLKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTNNNNNSMHLRELHAVGLMPNQQQQSLNNSCNSSMNHNNNSSSNRSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLTCRRCQLKFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEDVIVPVATKAAIERTAAMESAAADANAAATLSALGEGAETEDQFAEKGEAAGATTADKLANPDEEDSDDLDEDSSGDDDDSSGTGDDDDDDDTDDDEDGEGEDEDEEGDGGEGEDEEGVQPAAQLLPQQLHKADLNQDDDDLVEEVISSDDDDDDDGEVESDDDDEDDDDEEDDVEEPEPVGLAVRPLMNGKSKMPPLIVASSDDEDDGVMPIGDIIEEEFDEDADPDPEDAIEEVDEDDLDEGDVEDEPNVVSTASFSESESSTTTTSNSHSHSTGERRKKAVDQLNDPGFTCDLCQLCFDSQELLQSHIKSHILNGPKLSTASAAAAAAAAAAATASSKATALLTAAKAKPDSKSAVLANNNNSKTSSKTVAAAATH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00539798;
90% Identity: iTF_00539798;
80% Identity: -