Basic Information

Insect: Drosophila mauritiana
Gene Symbol: hang
Assembly: GCA_004382145.1
Location: NC:16276010-16289510[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.25 16 5.9 1.0 3 23 320 341 319 341 0.93

2 19 0.32 20 5.5 3.2 3 22 449 468 447 468 0.89

3 19 0.00054 0.033 14.3 3.3 1 22 581 602 581 604 0.90

4 19 0.063 3.9 7.8 0.1 2 21 616 635 615 636 0.93

5 19 0.00063 0.039 14.1 0.2 2 23 771 793 770 793 0.95

6 19 0.0018 0.11 12.6 0.1 1 23 801 824 801 824 0.96

7 19 1.5e-05 0.0009 19.2 0.1 2 23 909 930 908 930 0.97

8 19 0.00026 0.016 15.3 2.9 2 23 1012 1034 1011 1034 0.97

9 19 0.02 1.3 9.3 0.2 2 23 1043 1065 1042 1065 0.95

10 19 8.5e-05 0.0052 16.8 0.2 1 23 1078 1101 1078 1101 0.97

11 19 0.00011 0.007 16.4 1.1 1 23 1154 1176 1154 1176 0.99

12 19 0.0018 0.11 12.7 0.9 1 23 1184 1207 1184 1207 0.96

13 19 7.6 4.7e+02 1.2 0.2 2 13 1215 1226 1215 1228 0.85

14 19 2.9e-05 0.0018 18.3 1.4 3 23 1320 1340 1319 1340 0.98

15 19 0.0046 0.28 11.4 0.1 1 23 1375 1397 1375 1397 0.97

16 19 0.00054 0.033 14.3 0.6 2 23 1476 1498 1475 1498 0.93

17 19 1.6 96 3.4 0.1 2 20 1518 1536 1517 1538 0.91

18 19 0.006 0.37 11.0 0.4 3 23 1553 1573 1553 1573 0.98

19 19 9.2e-05 0.0057 16.7 2.1 1 23 1870 1892 1870 1892 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.25	16	5.9	1.0	3	23	320	341	319	341	0.93
2	19	0.32	20	5.5	3.2	3	22	449	468	447	468	0.89
3	19	0.00054	0.033	14.3	3.3	1	22	581	602	581	604	0.90
4	19	0.063	3.9	7.8	0.1	2	21	616	635	615	636	0.93
5	19	0.00063	0.039	14.1	0.2	2	23	771	793	770	793	0.95
6	19	0.0018	0.11	12.6	0.1	1	23	801	824	801	824	0.96
7	19	1.5e-05	0.0009	19.2	0.1	2	23	909	930	908	930	0.97
8	19	0.00026	0.016	15.3	2.9	2	23	1012	1034	1011	1034	0.97
9	19	0.02	1.3	9.3	0.2	2	23	1043	1065	1042	1065	0.95
10	19	8.5e-05	0.0052	16.8	0.2	1	23	1078	1101	1078	1101	0.97
11	19	0.00011	0.007	16.4	1.1	1	23	1154	1176	1154	1176	0.99
12	19	0.0018	0.11	12.7	0.9	1	23	1184	1207	1184	1207	0.96
13	19	7.6	4.7e+02	1.2	0.2	2	13	1215	1226	1215	1228	0.85
14	19	2.9e-05	0.0018	18.3	1.4	3	23	1320	1340	1319	1340	0.98
15	19	0.0046	0.28	11.4	0.1	1	23	1375	1397	1375	1397	0.97
16	19	0.00054	0.033	14.3	0.6	2	23	1476	1498	1475	1498	0.93
17	19	1.6	96	3.4	0.1	2	20	1518	1536	1517	1538	0.91
18	19	0.006	0.37	11.0	0.4	3	23	1553	1573	1553	1573	0.98
19	19	9.2e-05	0.0057	16.7	2.1	1	23	1870	1892	1870	1892	0.98

Sequence Information

Coding Sequence: ATGTGCGACGCTGCGGCGGCaacagcgacaacaacaacagcagtagcagcagccgtcgcaacaacaacagcatcgGTAGCATTGGAGGCCACAGCGACACAGCCTGGaacgacaacgacgacgacggcgGTAGCCACTGCGTCAGCGGGAACCACATCCCCTGAAGCGGCCAttccaacagcagcaacagcaacatcggcGAAACACAGCAACAGCGAACGGTCGGCGCGACAAAACTGCTGTCGCCTGTGCATCGCCCCACAAACCGAATGCATCTCGATCATCAATAGCTATGCAGCGGACAAGGAGCCGCTGTCCACCAAGATCCTCAACTGCGTCGGCATCAAGGTTACACCGCAGGATCGGCTGTCGCAGCAAATTTGCCACGCCTGCATCAGTTACCTGAACTCATGGCAGAGCTTCAAGAACCGGTGCTTCAGCTCGCAGGCGAAGCAGCGCCAGTGGCTGGATAACAACAAGAGCAAGCTCCTCAACTACCTGGACCTGAACAGTGCCGAGAATGGGGGAGGAGGCTTCTTCGATCAGCATTtgcatcagcaacagcaacaccaccaGCACTTGGAGAATGAGCTCGAagcggagaaggagaaggcGACGCCAACGGCCGCATCGACAGCCGCCAACATATTGGACGGCATACACTCGCTGAAGAAACGCAAATCCCTAACAGTCTATCCACTGCCTGCGATGCCCATCAAAGATGAGCCGATTGATACGGATGACGACTACCAGATGAAGTCCATAGACGAGTCCGATGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCGCTGACGGCCTCGGATTACGACTACACTGCGCAGCATGGCGTGAATGCCTCGTCCGTGGCTGCCTCGCTGCCGCCGAATGCGGTGGCCAATGTGGCAGCCGCCGGGGACTCCAAGGTGGCCAGCTGCAGGGCCTGCAGCCTGCAGTTCTCTACCCGGGCCAACGCCCGTCGCCACGAAAGGAATCTGCACCCAAACCTGTTCCAGTTGTCCACAGACTCCCCCCACAACACACCCATCACAAAGCCGACGCCCGCTTTGGCTGCCGCCTTGGAAATCCAACGGGCAGCGGCCGCGGCGGCCACCGCTGAGGCAAATCGAGCAGCGGGCGCCGCTGGCGGGAATATCTCCACGCAAAAGTATCGTCAGGTGGTGATGAACGCGTTCATTAAGTGCGAGGGCGGCGGCTACGACTACGATAATCCCGAACAGTACCGACCACTGCTCACCCGCGACAAAGTGGAGTTCATTGAGCAGAACGACGAGTTCCTCGAGCAATACCAGACGATGACCTGCCGATGTTGCAACAAGTACTTCAGCACGTACAAGAACTTCATGGCGCACGTTCGCAAGAAGTATCCGCAGCTGCCGCGCAACCTATGCTTCAATTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCGCATCTGAAGAAGCGGAATTGCATAAATCTCTTTAGAGTCTTGAATGCGCTGCGTGGGAAAACAACGACAGTGGTTGTGCCCATTGCAGATGATGGAACTGACGATGGAGCAACAGGAGCTGTTCCAGTTGCCGATGCCGGAGCAGGAGTGATGGCCATGAATAGTCCCACAGTGACAGCCAGCGGAGAAGTTGTTACACCCGGCGGCGGCTCCGAACGCCCAGAGAAACTGCGTGCCAAGGAACTGCTGGTCAACAAACTGTACGAGTGCAAGCTCTGTCCCAAGGGATTCCGCACCAAGCACGAGTTCCGCACGCATGTCTACGACAAGCACGCAGATGTCCAGCGCAAGGATAACAACTCGATACAGTGCAGCTTCTGTGGACTGGACTTTGCCGATCCCGTGGACAGACGGCGGCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACGTGCGATGCCAAGCTGGAAACGCACCAGCGTTTCCTCGATCATGTCTACCAGGATCACTTGGGCGGCGTGGGTGGTGGCGCGGTCAGCGACAATGCCTCCACCACTGGCAGCGGCATGGCCAGGAGCAACAGCATGGAACACTCGCCGGGCAAGAGGAGCCTGCTCGGCGCCTTGGGCGTTGGTTCCTCGGCGGAGGAGTCGCGAAGCAGCAGTGCGGCTCCGCCGCTGACCTCTACACCAAAACTGGTGGGCGGTAATCAGGTGGGTGGCGGTGGATCGACCAGCGCTTCTGCCGCCGCAGCCGCTCAGAGCTCGGCGAATCGCGATGCATCCGCACCCAAATCCCAGTACTTCTCCCGCATGCCGCAGGTTTGCCCCATTTGCGGCCAGCAgtacaacaactacaacaatgTGCTGCGCCACATGGAATCGAAGCATCCGAACAAACTGCCAGAGACATACAAGTGCGTGCGCTGCGGACTGGGCTATCCCCGGATCTCCTACCTGCGGGAGCACATGATCAATGTGCACGGAGTGGACAAGAATCGTCACTCTGGCGGCTTCGAATACATCGTGAATGCGGATGCCGTGAAGTTGGCGGACGGAAGTACGCCGAACGTCTACACGGGTCGCTACGATTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACACTCGATGATGACGAGGAGGAGCCTGGCAGCGTGGCCAAGAAGATGCGCCTGGatgacagcagcaacaacagcagcctGGTGGGCGTGGCTAGCCAGCAGAAGGAGTGCCCCATCTGCAATGCGGTGTTCAGCAACAACATTGGCCTGTCCAATCATATGCGCTCCCACTATACAGCCTCGAACGCAGTGAATGCAGCCTTGGCGGCTGCCAATCGAATGACACCCAAATCGCTAACGATTACCGCAACGCCAGCAACGGATTCGGAGTTCGGAGTTGGCGGAACAATGTCCGAGTCGGCTCCAGCAACGCCTGCCAATGTGCCACCGGCAATGGCCAATCAAACGCCCCAGGAGCAGGCAGTTTTTCGCCGGAGCCTTGACCAGGCAGCCGATCGACGCTTCCGGCGAATGCGCTGCCGCATCTGCCAGCGCCGCTTCAGTTCGAAGAAGTCCTATCGCTACCACATGCTCACCGATCATCAGGTGCAGAATGTGCAGTTCATCAAATGCAAGCTGTGCAACGCAGAGTTTGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGAAGGGCCATCAAGGATGAAATGATTATCAAGCAGTTCGAGTGTGAGGTTTGCTCGATTGTCTATAGTTCAGAGTcggagctgcagcagcacaAACGCAGTGTTCACAAGCTGACATCCGCCTCCGCTTCCACATCGGCGTCCACGTCCTCTAAGATCGACGACGACTCTCTAATGGATGAGGGCAAGCCGACATCATCGGATCTAGCTGATCTCTCCACCCTCGCGGCGGGTGGATCCACTGCATCTGCTCCACTGTACTGGTACCAGTGCAAGTACTGTCCATCAAACTTTAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTTGACTCGAACGATTATTCCTGCAAAGATTGCGGAAATGTCTACAGCGGACGCAAGAGTCTATGGGTTCATCGCTATAAGAAGCATCCGCAAGTGCCCAACCCAGCTGAGTGCTCGCTGTGCCGCAAGGTCTTCTTCGACCGCCAGATGCATGACAACCACACGCCCACCTGCAACCGCAAGCCGATCACCTTGACCGGTGCCCACCAGCAGCAGGATGGACAACTGCATTCACACCACACGACCAAAAGAACAATTTTCCGGCATAAGACcggcgatgacgatgacgaggaggatgacgatgagcagcagcaactggagGAGAGGGCCAATAGCGATGGCAATGGCACCACTGTGGGAGTGGCGTCGGGCAGTACTGCAGCTGCGGGCACGTCACTGAAGATCCGCATTCCGGAGGTGGCGTGCACCATTTGCGGCGCTCGCTTCACCGACCAGGAGCACTTTAGCAAGCACATCCAGAAGCACGAGCAAGAGCTGTACGTGGACAATCCGCTGGCGGCGATGTTCGATGATGGGCCGGCGGATGCCGGTCAGTTCCAGGTGGAGCGGCAGAATGAGAACGGGGAATACGCGTGCGATTTATGCGCCAAGACGTTCCCCCAGGTGATCGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGACCAACAACAATCAcacaaccaacaacaacaacaactcgaTGCACCTCCGCGAGCTGCATGCGGTGGGCCTGATGCccaaccagcagcagcagagccTCAACAACTCGTGCAACAGCAGCAtgaaccacaacaacaacagcagcagcaaccgcaGCAAGTCGATGAAGCGGAAACGTGAGCTGAAATGCGAATACTGCGCCTCCACCTTCATCAGCAATAACAATCTGCGTCGCCACATGTACGAGCTGCACAAACACGAGGTAAGCAATCTGCCCGAGCCGCCGGTGATTGTGGTGGACGATCACCTCACCTGCCGTCGCTGTCAGTTGAAGTTCGACACAAAGGAGCTGTGGATCGAGCACAAGCTGGCCGATGCGAAGGTGGTGCGACCTTTCTGCCCCTTCCAGTGGGGCTGTGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTGATGAACCATATTAACAACCATTTGAAGGAGGATGTCATAGTGCCAGTGGCCACTAAGGCGGCCATTGAGAGAACAGCGGCCATGGAATCAGCGGCAGCAGATGCGAACGCAGCGGCGACACTATCAGCATTGGGCGAAGGAGCCGAAACTGAAGATCAGTTTGCAGAGAAGGGTGAGGCTGCAGgggcaacaacagcagataaGTTGGCGAATCCCGACGAGGAGGATAGCGATGATTTGGATGAGGATAGCTCGGGCGACGACGATGATAGTTCGGGCACGGgagatgatgacgatgacgacgacacCGACGATGATGAGGATGGCGAGGGTGAAGATGAGGACGAGGAGGGAGATGGTGGCGAAGGCGAGGACGAAGAAGGTGTCCAGCCACCCGCTCAACTTTTGCCGCAACAGCTACACAAAGCGGATCTTAATCAGGACGACGATGATCTCGTCGAGGAGGTCATCACCTCcgatgacgacgatgacgatgatggaGAGGTGGAAAGtgacgatgacgacgaagatgatgatgatgaggaggACGATGTGGAGGAGCCGGAGCCAGTGGGATTGGCGGTGCGACCGCTTATGAATGGCAAATCAAAGATGCCGCCGCTGATAGTGGCCAGTTCGGATGATGAAGACGATGGTGTGATGCCCATAGATGACATTATCGAAGAGGAGTTCGATGAGGATGCCGATCCAGATCCGGAGGATGCCATTGAGGAGGTAGACGAAGATGATTTAGATGAGGGGGATGTGGAGGACGAGCCGAATGTGGTGTCGACGGCCTCCTTCTCGGAGAGCGAGTCCAGCACAACGACCACGTCcaattcgcattcgcattcgcattcaaCGGGTGAGCGGCGTAAGAAGGCCGTCGATCAGTTGAATGATCCCGGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTCCAGAGCCACATCAAAAGCCATATCCTCAATGGGCCAAAGCTCTCGAcagcgtcagcagcagcagcagcagcagccgccgccaCAGCAAGCAGCAAGGCAACAGCATTACTAACGGCAGCAAAGGCGAAGCCTGACTCCAAGTCAGCGGTGCTGgccaacaataataacagcaaGACAAGCAGCAAGACTGTGGCAGCAGCTGCGACACATTGA
Protein Sequence: MCDAAAATATTTTAVAAAVATTTASVALEATATQPGTTTTTTAVATASAGTTSPEAAIPTAATATSAKHSNSERSARQNCCRLCIAPQTECISIINSYAADKEPLSTKILNCVGIKVTPQDRLSQQICHACISYLNSWQSFKNRCFSSQAKQRQWLDNNKSKLLNYLDLNSAENGGGGFFDQHLHQQQQHHQHLENELEAEKEKATPTAASTAANILDGIHSLKKRKSLTVYPLPAMPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDVPLTASDYDYTAQHGVNASSVAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAAAATAEANRAAGAAGGNISTQKYRQVVMNAFIKCEGGGYDYDNPEQYRPLLTRDKVEFIEQNDEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPQLPRNLCFNCLKMNDSKALFISHLKKRNCINLFRVLNALRGKTTTVVVPIADDGTDDGATGAVPVADAGAGVMAMNSPTVTASGEVVTPGGGSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGAVSDNASTTGSGMARSNSMEHSPGKRSLLGALGVGSSAEESRSSSAAPPLTSTPKLVGGNQVGGGGSTSASAAAAAQSSANRDASAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEPGSVAKKMRLDDSSNNSSLVGVASQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITATPATDSEFGVGGTMSESAPATPANVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSESELQQHKRSVHKLTSASASTSASTSSKIDDDSLMDEGKPTSSDLADLSTLAAGGSTASAPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPNPAECSLCRKVFFDRQMHDNHTPTCNRKPITLTGAHQQQDGQLHSHHTTKRTIFRHKTGDDDDEEDDDEQQQLEERANSDGNGTTVGVASGSTAAAGTSLKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTNNNNNSMHLRELHAVGLMPNQQQQSLNNSCNSSMNHNNNSSSNRSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLTCRRCQLKFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEDVIVPVATKAAIERTAAMESAAADANAAATLSALGEGAETEDQFAEKGEAAGATTADKLANPDEEDSDDLDEDSSGDDDDSSGTGDDDDDDDTDDDEDGEGEDEDEEGDGGEGEDEEGVQPPAQLLPQQLHKADLNQDDDDLVEEVITSDDDDDDDGEVESDDDDEDDDDEEDDVEEPEPVGLAVRPLMNGKSKMPPLIVASSDDEDDGVMPIDDIIEEEFDEDADPDPEDAIEEVDEDDLDEGDVEDEPNVVSTASFSESESSTTTTSNSHSHSHSTGERRKKAVDQLNDPGFTCDLCQLCFDSQELLQSHIKSHILNGPKLSTASAAAAAAAAATASSKATALLTAAKAKPDSKSAVLANNNNSKTSSKTVAAAATH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00592530; iTF_00596792; iTF_00604995; iTF_00505548;
90% Identity: iTF_00592530; iTF_00596792;
80% Identity: -