Basic Information

Insect: Drosophila rubida
Gene Symbol: -
Assembly: GCA_035046165.1
Location: JAWNOF010000012.1:13260489-13263693[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00064 19.8 3.5 1 23 168 191 168 191 0.97

2 17 0.001 0.059 13.6 3.1 1 23 239 262 239 262 0.96

3 17 0.00056 0.033 14.4 3.2 1 23 327 350 327 350 0.96

4 17 0.0047 0.28 11.5 0.5 2 23 401 422 400 422 0.97

5 17 0.38 23 5.5 2.2 1 23 502 528 502 528 0.95

6 17 3.9 2.3e+02 2.3 0.6 1 20 535 554 535 556 0.75

7 17 0.02 1.2 9.6 0.6 1 23 565 587 565 587 0.94

8 17 0.00028 0.017 15.4 2.1 1 23 594 616 594 617 0.95

9 17 0.00035 0.02 15.1 1.4 2 23 625 646 624 646 0.96

10 17 0.00085 0.05 13.9 0.1 2 22 673 693 672 696 0.89

11 17 0.0026 0.15 12.4 0.6 1 23 736 759 736 759 0.96

12 17 1.8 1.1e+02 3.4 4.0 1 22 766 787 766 787 0.96

13 17 0.0045 0.26 11.6 1.7 1 23 796 819 796 819 0.98

14 17 1.6e-05 0.00094 19.3 0.5 1 23 838 861 838 861 0.97

15 17 0.74 43 4.6 0.1 1 23 871 893 871 893 0.91

16 17 5e-05 0.0029 17.7 3.1 1 23 899 921 899 921 0.98

17 17 5.1e-05 0.003 17.7 0.9 1 23 927 949 927 949 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00064	19.8	3.5	1	23	168	191	168	191	0.97
2	17	0.001	0.059	13.6	3.1	1	23	239	262	239	262	0.96
3	17	0.00056	0.033	14.4	3.2	1	23	327	350	327	350	0.96
4	17	0.0047	0.28	11.5	0.5	2	23	401	422	400	422	0.97
5	17	0.38	23	5.5	2.2	1	23	502	528	502	528	0.95
6	17	3.9	2.3e+02	2.3	0.6	1	20	535	554	535	556	0.75
7	17	0.02	1.2	9.6	0.6	1	23	565	587	565	587	0.94
8	17	0.00028	0.017	15.4	2.1	1	23	594	616	594	617	0.95
9	17	0.00035	0.02	15.1	1.4	2	23	625	646	624	646	0.96
10	17	0.00085	0.05	13.9	0.1	2	22	673	693	672	696	0.89
11	17	0.0026	0.15	12.4	0.6	1	23	736	759	736	759	0.96
12	17	1.8	1.1e+02	3.4	4.0	1	22	766	787	766	787	0.96
13	17	0.0045	0.26	11.6	1.7	1	23	796	819	796	819	0.98
14	17	1.6e-05	0.00094	19.3	0.5	1	23	838	861	838	861	0.97
15	17	0.74	43	4.6	0.1	1	23	871	893	871	893	0.91
16	17	5e-05	0.0029	17.7	3.1	1	23	899	921	899	921	0.98
17	17	5.1e-05	0.003	17.7	0.9	1	23	927	949	927	949	0.98

Sequence Information

Coding Sequence: aTGACGAGGACATGTAGAATCTGCGGCGGTGCAGATGGACGCTATTGGATTGAGACGCAAGTGAATAAGTATGCTGAGAAAACATTCCACCAACTCCTCTTGGAACTGGCAAAACTCGAGGTCGCCTTGGATCAAGTTGAGAAGCTCCCGCCTTGGCTTTGCCGTATTTGTGCACAGAAATTGGAAAATGCTTACGACTTCGTGCTGCAAGCCCGCGAATCTCATAAACTGTGGATTCAAAAACTCACAACAGACGTCAGCGTGGATGAAACCGATAAGGGCCCCCTCGAGTGTCTGCGTGAGACTCCAATACAATTGCTTGAGATTGAGGGCGTGACAATAAAGATGGAAGAACCCACAGAACCTGCCATGCCACAATCAGATCTAAACATTTCTGTTGATCCTCTAGTTAAGAAGAGCATAGTGGACGAGGAgagcgacgatgatgacgatgtgCCTTTGAAGCAGCGCAAAGTGAATCAAACGAAATTGCCAGTGAACCACAAATGCAATATTTGCGGGAAAGCTTTCAAATATGTAACAAACCTCTTCAGACATAAGCAGCGCGATCACCAGCATATGGATCAATGCAAgataaaatcaaaatcaagaGCTGAAAATCGTTCAGAGCCATTTCTTCACAATTCAGTAATGAGATCTACAGCTACTCGTAGCAGCACCAATTCAGACTTGGACACTGAAGATGATAACTACTACAAATGTGATCAATGCGACAAGTCCTACAAATACATAATGTTGCTAATCAGGCACAAGCACAAGGTTCATGGCGCCAATCAATTGCCTTCCGAGCCAATGCCAATATCAAGACGCAAGTCGAGTTCTGAAGAATCAGCCAAAGCGAGGCCTACTCAACATCAACGCGCAAAGCCGTCGAGTACAGATTCCTTAGTACACAGTTTAATCAAAGAGGTTAAAACACCGGAGGAAGACCTCGAAGGCACAAGCTCGGACAATTACTACAAATGCGATCAATGTGACAAATCCTACAAATACATTGTAAGCCTCATCAAGCACAAACACAGGGAGCACAGTGAATACAAAGATTCCGatgacgacgaagacgaagcATCGCTATGCACATACCCGACAGCAGCTTCAAACTCAAAGCCCACACGCATCGATCGACGGGTAAAAAGCTTTGATTTGCATCGCTGTAGGCCAAATGGCATTAAGGAGATTCAGTGCATGATTTGCTTACGTCGTTTTGGTAAACTGAGGGAGCTGCGCAATCATCTTAGAGCACATCCTATGAATATAACATTTGAGGCTCACGGTGAACCCATCGAACGCATTGCTGAGGGCTTCTATCGCACAGCTGTGGAGTCAACAGCTGCCGGCTTGAAAGCGCGCATTCTCAATGATCTCAAGGTTGGCATGTATGGCCGCTACTATTCTATTACCAATGAGGCGCGTTACGAGATGAATCTGGACAGCTCCGACACCGACAGCGATGGCGAATGTGGAGTTGTTGAGCGTCGTAGTTACGCCTGTGAACTCTGTGATTCACCTTCAACAATTTTCCCCCGCAAGTTTCAGTTACATGAACATCATCGACAGCAACACACTTGGCTCGAGGCGCCATACATCTGCTCGCGTTGTGATTCACGTTTCCTCAGTGCTCAGTTACTTGATCATCACACGAATAAACTTTGTCAGAATACCCTAAAACGCTTCATGTGCGACAAGTGCCCACAGCGCTTTTTTTGGCGGCGCAATTTGCGTGCCCATCTCGTCGAACACAAAAACAAGCAAGATAATTACCCCTGTGATCAGTGTTCACGTAGTTTTCAGGATAAAAGTGCAGTGACAAAGCACAAACTGATGCATCACGATGGCAGCCACGAGCTGATACCCTGTCGTTGGTGCACCCGTACATTCTATCGTCCGGCTTTATTGCATAAACATGTAAAACGACATGGCTTCACAGGAGAGGATTTGCCCTTGGCGGAGACATTACTGGCTTATGCCGCAAAGTCGTCCGGACCAAAGTCAATAGTTTGCAAGCTTTGCGATATGCAGTTTATTAGCACAGCCGATTTACGACGGCATATCTCGATGCAGGGCCACAGCGAAGAGGCTTCCAACTATATGATTAGCACGGAGGAAGGCTTCGAGTTGCATCTGGATGAGACGGACGATAGCGATGATGagactacaactacaaccacCTCCGCTGGCAGAACGTACAAGTGTGATCTTTGCGACGCGGTCTTTCAGCGGCGTCGCGACATGAGCGAACACCAGTATTCCCTGCATACCTTCGACAAACTGCCTCATTCCTGTGAACATTGTATCTACAAGACGGTCAATAAGTATATGATGCAGCATCACTTGCGTACGCAGTGTCTTAATGAGGagaagaaattcaaatgttccCGCTGTGGCTTCAAATTCATGTGGAAGGATAATCTCGATCAGCATATGAACAGCCAACATACCCATTTTTCAACTCAGGCCCCAGTTCAAACCAAAAGAAGTCGGCGCTTCAGATATCAGTGTCCGCATTGCTGGCGTTCTTTTGTTGTACAACCAAGCCTAGATAAACACATACGCGACATGCACGTGGCCAAAAAGAATCCCGGCAAAAAGTATCTCTGCTCATTATGTGGCCTGGAAGCGCTTACTCCCAACAAACTGGCTATCCACATGCAACGTCACAATGGCGAAAAACCCCATAAGTGCGATCTGTGCGACATGTCATTTACAGTCTACTACGAGCTGAAGGTGCATCGCCGAAAGCATACGGGCGAGCGCCCCTATCAATGCACATTTTGCGCCAAAGATTTTGCACGCCCCGATAAGCTGAGGCGGCATGTTTACATGCATAGTGTGAAACGTTAG
Protein Sequence: MTRTCRICGGADGRYWIETQVNKYAEKTFHQLLLELAKLEVALDQVEKLPPWLCRICAQKLENAYDFVLQARESHKLWIQKLTTDVSVDETDKGPLECLRETPIQLLEIEGVTIKMEEPTEPAMPQSDLNISVDPLVKKSIVDEESDDDDDVPLKQRKVNQTKLPVNHKCNICGKAFKYVTNLFRHKQRDHQHMDQCKIKSKSRAENRSEPFLHNSVMRSTATRSSTNSDLDTEDDNYYKCDQCDKSYKYIMLLIRHKHKVHGANQLPSEPMPISRRKSSSEESAKARPTQHQRAKPSSTDSLVHSLIKEVKTPEEDLEGTSSDNYYKCDQCDKSYKYIVSLIKHKHREHSEYKDSDDDEDEASLCTYPTAASNSKPTRIDRRVKSFDLHRCRPNGIKEIQCMICLRRFGKLRELRNHLRAHPMNITFEAHGEPIERIAEGFYRTAVESTAAGLKARILNDLKVGMYGRYYSITNEARYEMNLDSSDTDSDGECGVVERRSYACELCDSPSTIFPRKFQLHEHHRQQHTWLEAPYICSRCDSRFLSAQLLDHHTNKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQDNYPCDQCSRSFQDKSAVTKHKLMHHDGSHELIPCRWCTRTFYRPALLHKHVKRHGFTGEDLPLAETLLAYAAKSSGPKSIVCKLCDMQFISTADLRRHISMQGHSEEASNYMISTEEGFELHLDETDDSDDETTTTTTSAGRTYKCDLCDAVFQRRRDMSEHQYSLHTFDKLPHSCEHCIYKTVNKYMMQHHLRTQCLNEEKKFKCSRCGFKFMWKDNLDQHMNSQHTHFSTQAPVQTKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLEALTPNKLAIHMQRHNGEKPHKCDLCDMSFTVYYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579434;
90% Identity: iTF_00509250; iTF_00520783; iTF_00614336; iTF_00595404;
80% Identity: -