Basic Information

Insect: Drosophila rubida
Gene Symbol: Hr39
Assembly: GCA_035046165.1
Location: JAWNOF010000014.1:13643937-13649673[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.46 3.6e+03 -3.2 0.1 155 192 30 67 6 104 0.46

2 4 0.43 3.3e+03 -3.1 15.2 40 157 181 304 165 357 0.47

3 4 1.2e-21 8.8e-18 64.7 7.4 1 132 494 668 494 675 0.79

4 4 2.1e-83 1.6e-79 268.0 0.6 183 408 689 905 684 905 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.46	3.6e+03	-3.2	0.1	155	192	30	67	6	104	0.46
2	4	0.43	3.3e+03	-3.1	15.2	40	157	181	304	165	357	0.47
3	4	1.2e-21	8.8e-18	64.7	7.4	1	132	494	668	494	675	0.79
4	4	2.1e-83	1.6e-79	268.0	0.6	183	408	689	905	684	905	0.96

Sequence Information

Coding Sequence: ATGCCCAACATGTCGAGCATTAAGACGGAGCAGAGCGTCTCGCCCGGCGCCGTCGCcggcgccagcggcagctacCAGCTGCCGGTGAACATGTCCTCGACGCCCACGGCGACGACGCGCCACAACGTCTCCGTGACGAACATCAAGTGCGAGCTGGACGAGCTGCCGACGCCCAACGGCAACCTGGTGCCCGTCATCgccagctacaacaacagccacaatcacaacaaccacagcaaccacagcaatcACAATCACGGCGGCAGCCTGCGCATTCCGCTCGGCCTCGGCCTGCAGGCGGCCAAGGAGGACGAGTCCGACTCGGAGCCGGAGCTGGCGAGCATTGAGAATCTGCAGAAGGTGCGGCGACGCGCCGCCGACAAGAACGGCCCCCGTCCCATGTCCTGGGAGGGCGAGCTCAGCGAGTCGGAGGCGGCCGCCGACGAGGAGCTGATGGACACCGAGACGGTCGTCAAGAGCGAGTCCAGCGGCGGCCAGGTGGCCGCCATGATGCAGCCCATCAAAACGGAGCTCGAGCACATAGCcggcgagctgcagcagcagcagcacgagcaacagcagccgcaccATCACttgcagcaccaccagcagctgctgcagcaccaacagcagcaacaacagcagcagcagcagcagcagctgcccaagCAGCACTTCGGTCAGCAGCCGAAcaacaagctgaagctggcgcCCACGCAGAGCGACCCCATCAACCTGAAGTACGAGCCGGCGACGggggcgacgacgacgacgacgacgctgtgCGAGCGCAGCAAGTCGAGCAGTGGTGGCcacctgccgctgctgcccgcGAATCCCAGTCCCGACTCCGCCATACATTCCGTCTACACGCACAGCAGCCcctcgcagtcgccgctgacGTCGCGCCACGCCCCCTACACGCCCTCGCtgagccgcaacaacagcgacgcctcgcacagcagctgctacagctacagctccgAGTTCAGTCCCACCCACTCGCCCATCCAGGCGCGCCACGCGCCCCCCGGTGGCGCCTCGCTGCTGCCcgtggcagctgccagcagctttgccaacggcggcggcgcccTGCACCACCACAGCGTGCTGTACAGACCGCTCAATGTGGAGCCGGCGGGCAGCTCAACGGTGGTTGGGCAGGAGGCGCAAAATCTCAGCATGGAGGCGGGCGGCGCGTCGCTGGATGCGTcgacagcgctgccagcgtcgccgGCGGGCATCTCGCGGCAGCAGCTGATCAACTCGCCGTGCCCGATCTGCGGCGACAAGATCAGCGGCTTCCACTACGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACCGCAAGAACTACGTCTGTGTGCGCGGCGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAGAAGTGCCCGGCCTGCCGCTTCGAGAAGTGCCTGCAGAAGGGCATGAAGCTGGAGGCCATACGCGAGGATCGCACGCGCGGCGGTCGCTCGACCTATCAGTGCTCCTACACGCTCCCCAACTCCATGCTCAGTCCGCTGCTCAGTCCCGACCaggctgccgccgccgccgcagcggccgccatcgtcaatcagcagcagcagcagcagcagcagcaacagcagcagcagcagcatcaccagcgcttgcatcagcagcaccaacagcagcagcagcatcagccgcagcagcagcagacagctcagcagcagcagcagcaacacgcgCCTCTCAACGGCTTtggcgggggagggggcagcggctgcagcggcagcagcagcgtcggctCCAACTCCCTGCCGGCCAGCCCCAGCCTGGGCACGTCCATCAAGACGGAGCAAACGGAGCCGCTCAACCACCACGCGACGCGACCCTCAAGCATTCCAGCCCTCTTGCAGGAGATCATGGATGTTGAACATCTCTGGCAGTACACCGACGCTGAGTTGGCGCGCATCAATCAGCCGCTGTCCTCGTTCGCCAGCGGCGGCTCCTCGTCGGGCTCTGGCGGCGGGTCGGGCGGGGGCGGACATCACACTGCCAACGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCGTCGAACGGCGAGAATGCCAATCCCGATCTGATCGCCCATCTCTGCAATGTGGCCGATCATCGGCTCTACAAGATCGTCAAGTGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTAATCAACTCGTGGTGCGAGCTGTTGCtcttctcctgctgctttCGATCCATTGACACGCCCGGCGAGATCAAGATGTCGCAGGGCAGAAAGATTACGCTGGCGCAGGCCAAAACCAATGGCTTGCAGGCTTGCATTGAGCGCATGCTGAATCTGACGGATCACTTGCGACGTCTACGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAAtcgtgctgctgcagtcagACACCACGGAGCTGCACGAGGCGGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTCTGCAGGCGTACACGCTGGCCCACTATCCCGATACGCCGTCCAAGTTTGGGGAGCTCTTACTGCGCATTCCCGATCTGCAGCGCACTTGTCAGTTGGCCAAGGAGATGCTGACGATCAAGACGCGCGATGGTGCCGACTTCAACCTGTTGATGGAGCTGCTGCGGGGAGAGCATTGA
Protein Sequence: MPNMSSIKTEQSVSPGAVAGASGSYQLPVNMSSTPTATTRHNVSVTNIKCELDELPTPNGNLVPVIASYNNSHNHNNHSNHSNHNHGGSLRIPLGLGLQAAKEDESDSEPELASIENLQKVRRRAADKNGPRPMSWEGELSESEAAADEELMDTETVVKSESSGGQVAAMMQPIKTELEHIAGELQQQQHEQQQPHHHLQHHQQLLQHQQQQQQQQQQQQLPKQHFGQQPNNKLKLAPTQSDPINLKYEPATGATTTTTTLCERSKSSSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPGGASLLPVAAASSFANGGGALHHHSVLYRPLNVEPAGSSTVVGQEAQNLSMEAGGASLDASTALPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAIVNQQQQQQQQQQQQQQHHQRLHQQHQQQQQHQPQQQQTAQQQQQQHAPLNGFGGGGGSGCSGSSSVGSNSLPASPSLGTSIKTEQTEPLNHHATRPSSIPALLQEIMDVEHLWQYTDAELARINQPLSSFASGGSSSGSGGGSGGGGHHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLAKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00589591;
80% Identity: iTF_00589591;