Basic Information

Insect: Drosophila robusta
Gene Symbol: hang
Assembly: GCA_004143805.1
Location: SCDV01001444.1:12452-30647[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.27 34 5.7 1.0 3 23 274 295 273 295 0.93

2 18 0.78 98 4.3 3.2 3 22 402 421 400 421 0.89

3 18 0.00058 0.073 14.1 3.3 1 22 523 544 523 546 0.90

4 18 0.067 8.4 7.7 0.1 2 21 558 577 557 578 0.93

5 18 0.00067 0.085 13.9 0.2 2 23 714 736 713 736 0.95

6 18 0.0019 0.24 12.5 0.1 1 23 744 767 744 767 0.96

7 18 0.00012 0.015 16.3 0.1 2 23 853 874 852 874 0.97

8 18 0.00028 0.035 15.1 2.9 2 23 979 1001 978 1001 0.97

9 18 0.022 2.7 9.2 0.2 2 23 1010 1032 1009 1032 0.95

10 18 0.0012 0.15 13.2 0.1 1 23 1045 1068 1045 1068 0.97

11 18 0.00012 0.015 16.3 1.1 1 23 1117 1139 1117 1139 0.99

12 18 0.0019 0.24 12.5 0.9 1 23 1147 1170 1147 1170 0.96

13 18 0.066 8.3 7.7 0.4 2 19 1178 1195 1178 1196 0.94

14 18 2.6e-05 0.0032 18.4 0.4 3 23 1299 1319 1298 1319 0.98

15 18 0.0018 0.22 12.6 0.1 1 23 1354 1376 1354 1376 0.97

16 18 0.00059 0.074 14.1 0.7 2 23 1468 1490 1467 1490 0.93

17 18 0.0062 0.78 10.9 0.3 3 23 1546 1566 1546 1566 0.98

18 18 6.8e-05 0.0086 17.1 2.0 1 23 2016 2038 2016 2038 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.27	34	5.7	1.0	3	23	274	295	273	295	0.93
2	18	0.78	98	4.3	3.2	3	22	402	421	400	421	0.89
3	18	0.00058	0.073	14.1	3.3	1	22	523	544	523	546	0.90
4	18	0.067	8.4	7.7	0.1	2	21	558	577	557	578	0.93
5	18	0.00067	0.085	13.9	0.2	2	23	714	736	713	736	0.95
6	18	0.0019	0.24	12.5	0.1	1	23	744	767	744	767	0.96
7	18	0.00012	0.015	16.3	0.1	2	23	853	874	852	874	0.97
8	18	0.00028	0.035	15.1	2.9	2	23	979	1001	978	1001	0.97
9	18	0.022	2.7	9.2	0.2	2	23	1010	1032	1009	1032	0.95
10	18	0.0012	0.15	13.2	0.1	1	23	1045	1068	1045	1068	0.97
11	18	0.00012	0.015	16.3	1.1	1	23	1117	1139	1117	1139	0.99
12	18	0.0019	0.24	12.5	0.9	1	23	1147	1170	1147	1170	0.96
13	18	0.066	8.3	7.7	0.4	2	19	1178	1195	1178	1196	0.94
14	18	2.6e-05	0.0032	18.4	0.4	3	23	1299	1319	1298	1319	0.98
15	18	0.0018	0.22	12.6	0.1	1	23	1354	1376	1354	1376	0.97
16	18	0.00059	0.074	14.1	0.7	2	23	1468	1490	1467	1490	0.93
17	18	0.0062	0.78	10.9	0.3	3	23	1546	1566	1546	1566	0.98
18	18	6.8e-05	0.0086	17.1	2.0	1	23	2016	2038	2016	2038	0.99

Sequence Information

Coding Sequence: ATGTGCGACACTGTCGctacaacaatagcagcaggcACTGGAACGGGCACAGGCActggaacgggaacgggagctGCTGGCGCGGCCGATATAGCTGCGACAGCAATGGAGGAGCGAACGCGACAAAGCTGCTGTCGCCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATTATTAACAGTTATGCGGCCGATAAGGAGCCGTTGGccacaaaaatacacaactGCGTAAATATCAAGATCACGCCATTGGATCGTCTATCGCTGCACATCTGCCACGCCTGCATCAGCTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGTCGAAGCAGCGGCAATGGCTGGAGACCGACAAGACCAAGCAGCAGACACTACTCGGCTATTTGGATTTGAATAAGACGGAGAACGGCAGCTCCgctgagcaacagcagcaacacgaaTCGAAAATCGATTCGGCGACGGCTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATACCCTCGCTGAAGAAGCGCAAATCGTTAACAGTTTATCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGGATGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAGTCCGACGATATGATGGATCCTACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTATACGGCGCAGCACGGCGTGACGGCGgtcgcggcggcggcaacgctGCCCGCCAGCGCGGTCGCCAATGTGGCCGCCGCCGGTGACTCCAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCGCGTCGCCACGAGCGCAATCTGCACCCAAATCTGTTTCAATTGTCGACAGACTCGCCAAATAATACGCCCATCACGAAACCGACGCCGGCACTGGCCGCCGCCCTGGAGATACAGCGGGCAgccgccgcggccgctgcCACCGCGGAGGCAACAaaagccgccgccggcggcaacATATCAGCCCAAAAATATCGCCAGGTGGTTATGAACACGTTCATCAAGTGCGAGAACGGCGGCTACGACTACGACAGTCCCGAGCAgtaccagcagctgctcaccCGGGACAAGGTGGAGTTCATTCAGGAGAACAACGAGTTCCTCGAACAGTACCAAACGATGACCTGTCGCTGCTGCAACAAATACTTCAACACGTACAAGAACTTTATGGCCCATGTGCGCAAAAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATATCGCATCTAAAGAAGCGCAACTGCATCAACTTGTATCGTGTGCTGAACGCTTTGCGCATCAAGCAGCCAAACTTTTCCCATGCCAACGCATCCGGGCTGGTTGTCGCAACGGACGGGCAGCAGCTCCAgatgcatcatcatcatcatcatcagcagctgctggccggcgGCGAAGCGTCATCGGAACGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAATAAGCTGTACGAGTGCAAACTCTGCCCGAAGGGCTTTCGCACCAAGCACGAGTTTCGCACCCATGTCTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAATTCGATACAGTGCAGCTTCTGTGGGCTGGACTTTGCCGATCCAGTGGATCGGCGTCGCCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACCTGTGATGCCAAATTGGAGACGCATCAGCGTTTTCTCGATCACGTCTATCAGGATCATCTGGGCGGCGTCGGCAGCGACAATGCCTCCACGGCGAACAGCGGGCTCGACCATTCGCCCGGCAAGCGCAGCCTGCTGGGCGCCCTCGGCATCGGTGTCTGTCAGTCATCGAATGATGAGTCGCGCAGCAGTggccaccacaacaacagtgCAGCTGAAACGCCGCTCACCTCGACACCGAAACCGgctgcagcaggaacagcagctgcagcagcagcagcatcagcgggcgcatcagcagcagcgaccaGTGGCGGCTCCGCGTCCGGCAATCGGGATGCGCCCAAATCGCAGTATTTCTCGCGCATGCCGCAGGTGTGCCCCATCTGTGGCCAGCagtacaacaactacaacaacgtTCTGCGCCACATGGAGTCGAAGCATCCCAACAAACTGCCCGAGACCTACAAGTGTGTCCGTTGCGGGCTCGGCTATCCGCGAATCTCATACCTGCGCGAGCACATGATCAATGTCCATGGCGTCGACAAGAATCGGCACTCGGGCGGCTTTGAGTATATTGTCAATGCCGATGCGGTCAAATTGGCCGATGGCAGCACGCCAAATGTCTACACCGGACGCTACGACTATGTGATGAAGGATCTAATGTCAATAACAAATGGTGGGACACTcgATGACGATGAGGAGGAGAGCGGCAGCGTTGCCAAGAAGATGCGGCTggacgacagcagcaacaacagcagcctcAACATGAGCCTGGCCAACCAGCAGAAGGAGTGCGCCATCTGCAACGCGGTgttcagcaacaacatcggGCTGTCCAATCACATGCGCTCCCATTACACCGCCTCAACGACGACGAGCGCCGCGCTGGCGGCGGCCAATCGCATGACGCCCAAATCGCTGACAATTACCGCCACGCCGCCGCTGGAAACGGCGGTCGTGTCGTCCACGGCGCCAGCAcctgccacagccacaacagcagcagcgacagcggcagcagcatcggcagcagcagcaactataacagctgcagctgcagctgcagccggcgGCAGCTTGCCACCGGCGATGGCAAACCAAACGCCACAGGAGCAGGCGGTATTCCGGCGCAGTCTCGATCAGGCGGCCGATCGACGGTTCCGGCGCATGCGCTGCCGCATCTGCCAGCGCAGATTCAGCTCGAAGAAATCGTATCGCTATCACATGCTCACCGACCATCAGGTGCAGAACGTCCAGTTCATCAAGTGCAAGCTGTGCAACGCAGAGTTCGCCTACGAGAAGGGTCTCAAGGTGCATCTGTTCAAGGTGCACGGTCGCGCCATCAAGGACGAGATGATCGTCAAGCAGTTCGAGTGTGATATCTGCTCCATTGTCTACAGCTCCGAGCTGGAGCTCCAACAGCACAAGCGCAGCGTCCACAAGTCCCACTCGGCTGgggccgccgccggcgccgccgtcgtcgaTCCCAACAAATCGTTGAAATCAGCTACAGCTACCGCTACCTCAGCCTCCGAACTGGCCGAGACATCCGGCACGGCCGCAACAGCCCTGCCCCTCTACTGGTACCAGTGCAAGTACTGTCCATCCAACTTCAACACCAACAAGAAACTGGCCATTCACATCAACTCGCACGACGAGTTCGACTCCAACGATTACTCCTGCAAGGACTGCGGCAACGTCTACAGCGGCCGCAAGAGCCTCtggGTGCATCGCTATAAGAAGCATCCGCAGGTGCCGGATCCCGCTGAGTGCACGCTGTGCCGCAAGATGTTCTTTGACCGCCAGATGCTGGAGAATCACACGCCCACCTGCAATCGGAAGCCCATCACTGCCACTGGCGCCCATCAGcaggatcagcagcagcagcagcaacagcagcaacaacagcagcagcagctgcagcagcagcaacagcatcagcgtAACATCTTCAAGCACAAGACgggcgacgatgatgatgacgaggatgatgaccagctgctgctgctggacgatGGCGTCGGCGGCGCCATCGGCAGTGATAGTAACGGCGGCAATGCGATTGCGGCGGCAAACAATCCGAGCACGATCAGCACGAGCACACTGAAGATACGGATACCGGAGGTGGCGTGCACCATTTGCGGTGCTCGGTTCACCGATCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGACCTCTATGTGGACAATCCATTGGCGGCGATGTTCGATGATGGTCCAGCGGACGCTGGCCAATTTCAGGTGAAGCACCAGAACGAGAATGGCGAATACGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGACTGCGCTCAAGGTCCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCAATCATCGACGGCGAAGCGACAACGctgaacaacagcagcagcaacaacaacaacaacaacaattcgctGAGCTCCTCGTCGATGCTGCATCTGCGCGAGCTGCATGCGGTGGGCCTGATGCCCAaccagcagcaccagaaacagcagcagctgcagcagcagcaacaacaacagcagcagcagcagcatcagagGAACAACACGTCGAGCAGCTCGAGCAAGTCGCTGAAGCGGAAACGTGAGCTGAAATGCGATTACTGCGCCTCCACgttcatcagcaacaacaatctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCCACCTGCCGGAGCCGCCGGTGATCGAGGTGGATGAGCCGCTCACgtgccgccgctgcggcgATCTGCAGTTCGAGACGAAGGAGCTGTGGATCGAGCACAAGCTCTCCGATGCCAAGGTGGTGCGTCCGTTCTGTCCGTTTCAGTGGGGCTGCGATCTGTGCGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATCAACAATCATCTCAAGGAGGATGTGATTGTGCCCGTGGCGGtggccgccgccaccgccgccgccgccaagcCAGCGGCAACTGCTCCATTGCTAACGAATAagaatgcaacaaaaacaacgacagcaactgcagcagcagcaacagcaactgcagcaacgacaacaacaacaacacccacGAAGGCAACCATTAAAGCGGCGGCGAGAGAGATGAAggctaagcagcagcaggaggaggaggatgaggaCGCAGAGGCGCAGGCGGAGTTGAAGTTGGCGAAGCAGCGGCATGGTGAGGAGCATGACAGTGATATGGATGACAGCGATAGTGGCGATGATGAGGACAGCACAAGTGCTggcgacgatgacgacgatgatgacgatgacgaggaGGACGGCGAGgtcgatgacgatgatgatgatgaggacgacgatgatgacgatgacgatgacgaggaTGAAGATGTtgtacagcagcagcagcagctgctgcagcaaaaacaacagcaacaacagcagccactcaacagcagcagcaacaacaacaacaacaacaatagcaacaacagtacGAGTGTTGTTGCCAACGATGATATCGATGATCTCATTGAGGAGGTAATCGAGGTGGATGGGATGGTCGAGGAGCTGGAAGATgatgaggacgaggacgatgacgacgatgatgatgacgatgatgtgGATGAAGTCGATGACGACGATGGCAACTCAACGGATGAGCACCAGGAGCTGAGAGCCGGCAATGCCAAGCAGGAGCAGCATCAGCCGAGGCGACTCAACTTTGACTACGGCCGGTCAGACAGCGCCAAGCtgaatggcaatggcaaagaGGCgctggcaaaggcaaaggcacaGCAGCCGGTGCTGGTCATGCACAGCTCCGAGGAGGATGAGGGcgaggaggatgaggaggacgatgatgttgatggtgtggatgatgatgatgaggatgcGGGCGGCGTGGGTGAGCCGATGAACATCGATGATATTATTGAAGAGGACGATggtgaagatgatgatgatgatgatgacgatgacgatgtgGTTGGTGTCGATGGTGCTGTTGTTgaggatgatgatgttgaGGAAGACATGGATGAGGACGatgtcgacgacgacgatgtcgatgatgacgatgacgagcACATCGGCAACGGCGATGCTCACAACGTTGCTGGCCGCACCGCCAGCGTGGgtgatgccgatgccgatggtGGGACATCATCATCCGAGAGcgagtcaacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAAACTGTAGTTAAGTCGGCGGCACATGGCGCTGCCGCCGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTcccaggagctgctgcagtcaCATATTAAGAGCCATTTTCTAAATGGCCCAtcggcgggcagcagcagcagcgccagcggcagcggcagcggcagtagctccaccagcagcagcaacagaagcagaagtagcagcagcaacggcgtcgtcgccgccagtcgtggcaacaacaacaacaacaataataataacaataaaagcaaaaccaaaaagtcCGGCTTGGATCCAACGCcaaagacgacgacgacgacgacgacgacaacagcaactgctgcagctgtggaTGCTGCAGCAAGCCTGAACTGA
Protein Sequence: MCDTVATTIAAGTGTGTGTGTGTGAAGAADIAATAMEERTRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLETDKTKQQTLLGYLDLNKTENGSSAEQQQQHESKIDSATAAAEKASANILDGIPSLKKRKSLTVYPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAATLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGYDYDSPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRIKQPNFSHANASGLVVATDGQQLQMHHHHHHQQLLAGGEASSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGSDNASTANSGLDHSPGKRSLLGALGIGVCQSSNDESRSSGHHNNSAAETPLTSTPKPAAAGTAAAAAAASAGASAAATSGGSASGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEESGSVAKKMRLDDSSNNSSLNMSLANQQKECAICNAVFSNNIGLSNHMRSHYTASTTTSAALAAANRMTPKSLTITATPPLETAVVSSTAPAPATATTAAATAAAASAAAATITAAAAAAAGGSLPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELQQHKRSVHKSHSAGAAAGAAVVDPNKSLKSATATATSASELAETSGTAATALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQLQQQQQHQRNIFKHKTGDDDDDEDDDQLLLLDDGVGGAIGSDSNGGNAIAAANNPSTISTSTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVKHQNENGEYACDLCAKTFPQVTALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSNNNNNNNSLSSSSMLHLRELHAVGLMPNQQHQKQQQLQQQQQQQQQQQHQRNNTSSSSSKSLKRKRELKCDYCASTFISNNNLRRHMYELHKHEVSHLPEPPVIEVDEPLTCRRCGDLQFETKELWIEHKLSDAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAVAAATAAAAKPAATAPLLTNKNATKTTTATAAAATATAATTTTTTPTKATIKAAAREMKAKQQQEEEDEDAEAQAELKLAKQRHGEEHDSDMDDSDSGDDEDSTSAGDDDDDDDDDEEDGEVDDDDDDEDDDDDDDDDEDEDVVQQQQQLLQQKQQQQQQPLNSSSNNNNNNNSNNSTSVVANDDIDDLIEEVIEVDGMVEELEDDEDEDDDDDDDDDDVDEVDDDDGNSTDEHQELRAGNAKQEQHQPRRLNFDYGRSDSAKLNGNGKEALAKAKAQQPVLVMHSSEEDEGEEDEEDDDVDGVDDDDEDAGGVGEPMNIDDIIEEDDGEDDDDDDDDDDVVGVDGAVVEDDDVEEDMDEDDVDDDDVDDDDDEHIGNGDAHNVAGRTASVGDADADGGTSSSESESTTTTSHSIGERRKKTVVKSAAHGAAADQSNSSYTCDLCQLCFDSQELLQSHIKSHFLNGPSAGSSSSASGSGSGSSSTSSSNRSRSSSSNGVVAASRGNNNNNNNNNNKSKTKKSGLDPTPKTTTTTTTTTATAAAVDAAASLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00541894;
90% Identity: iTF_00598302;
80% Identity: -