Basic Information

Insect: Drosophila melanica
Gene Symbol: hang_1
Assembly: GCA_004143765.1
Location: SCDT01001413.1:1500-19485[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.23 24 5.8 1.0 3 23 279 300 278 300 0.93

2 17 0.68 68 4.4 3.2 3 22 407 426 405 426 0.89

3 17 0.0005 0.051 14.2 3.3 1 22 520 541 520 543 0.90

4 17 0.058 5.8 7.7 0.1 2 21 555 574 554 575 0.93

5 17 0.00058 0.059 14.0 0.2 2 23 712 734 711 734 0.95

6 17 0.0017 0.17 12.6 0.1 1 23 742 765 742 765 0.96

7 17 0.00013 0.013 16.1 0.2 2 23 851 872 850 872 0.97

8 17 0.00024 0.024 15.2 2.9 2 23 981 1003 980 1003 0.97

9 17 0.019 1.9 9.3 0.2 2 23 1012 1034 1011 1034 0.95

10 17 0.00075 0.075 13.7 0.2 1 23 1047 1070 1047 1070 0.97

11 17 0.00011 0.011 16.4 1.1 1 23 1113 1135 1113 1135 0.99

12 17 0.0016 0.16 12.6 0.9 1 23 1143 1166 1143 1166 0.96

13 17 0.045 4.6 8.1 0.4 2 19 1174 1191 1174 1192 0.95

14 17 2.2e-05 0.0022 18.5 0.4 3 23 1283 1303 1282 1303 0.98

15 17 0.0042 0.42 11.3 0.1 1 23 1338 1360 1338 1360 0.97

16 17 0.00051 0.051 14.2 0.7 2 23 1451 1473 1450 1473 0.93

17 17 0.0054 0.54 11.0 0.3 3 23 1529 1549 1529 1549 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.23	24	5.8	1.0	3	23	279	300	278	300	0.93
2	17	0.68	68	4.4	3.2	3	22	407	426	405	426	0.89
3	17	0.0005	0.051	14.2	3.3	1	22	520	541	520	543	0.90
4	17	0.058	5.8	7.7	0.1	2	21	555	574	554	575	0.93
5	17	0.00058	0.059	14.0	0.2	2	23	712	734	711	734	0.95
6	17	0.0017	0.17	12.6	0.1	1	23	742	765	742	765	0.96
7	17	0.00013	0.013	16.1	0.2	2	23	851	872	850	872	0.97
8	17	0.00024	0.024	15.2	2.9	2	23	981	1003	980	1003	0.97
9	17	0.019	1.9	9.3	0.2	2	23	1012	1034	1011	1034	0.95
10	17	0.00075	0.075	13.7	0.2	1	23	1047	1070	1047	1070	0.97
11	17	0.00011	0.011	16.4	1.1	1	23	1113	1135	1113	1135	0.99
12	17	0.0016	0.16	12.6	0.9	1	23	1143	1166	1143	1166	0.96
13	17	0.045	4.6	8.1	0.4	2	19	1174	1191	1174	1192	0.95
14	17	2.2e-05	0.0022	18.5	0.4	3	23	1283	1303	1282	1303	0.98
15	17	0.0042	0.42	11.3	0.1	1	23	1338	1360	1338	1360	0.97
16	17	0.00051	0.051	14.2	0.7	2	23	1451	1473	1450	1473	0.93
17	17	0.0054	0.54	11.0	0.3	3	23	1529	1549	1529	1549	0.98

Sequence Information

Coding Sequence: ATGTGCGACACTGTCGTtacaacagtagcagcaggcACTGGAACGGTCACAGCCACTGGAAcgggaacaggaacaggagctgCTGGCGCGGCGGATActgcagcgacaacgacagcaatgGAGGAGCGTACGCGAAAAAGTTGCTGTCGCTTGTGCATTGCACCCGCTAGCGAATGCATTTCGATAATTAACAGTTATGCGGCCGATAAGGAGCCGCTGGccacaaaaatacacaactgCGTAAATATCAAGATCACGCCATTGGATCGGCTATCTCTGCACATTTGCCACGCCTGCATCAGCTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGACCAAGCAGCGACAATGGCTGGAGACAGACAAGAGCAAGCAACAGACGCTACTTGGCTATTTGGACTTGAATAAGACGGAGAACGGCAGCTCCACGgaccatcagcagcaacatcacgaattgaaaaatgattcggcgacagctgcagctgaaaagGCGTCCGCCAACATTTTGGATGGCATACCCTCGCTGAAGAAACGCAAATCGTTAACAGTCTATCCGCTGCCTGCTGTGCCCATTAAGGATGAGCCCCTGGATGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAGTCCGACGACATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCTGACTATGATTACACGGCGCAGCACGGCGTgacggcggtggcggcggcggcaacgctGCCCGCCAGCGCTGTGGCGAATGTGGCCGCCGCCGGGGACTCCAAGGTGGCCAGCTGCCGGGCATGCAGTCTGCAGTTTTCGACGCGGGCAAATGCGCGACGCCACGAGCGCAATCTGCATCCAAATCTGTTCCAATTGTCGACAGACTCGCCAAATAATACGCCGATCACAAAACCGACGCCGGCACTTGCCGCCGCACTGGAGATACAGCGGGCAGCTGCCGCGGCGGCTGCCACCGCGGAGGCAACAAAGGCCGCCGCCGGCGGCAACATATCAGCGCAAAAATATCGCCAGGTGGTGATGAACACGTTCATCAAGTGCGAGAACGGCGGCTACGACTACGACAGTCCCGAGCAGtaccagcagctgctcaccCGCGACAAGGTGGAGTTCATTCAGGAGAACAACGAGTTTCTCGAACAATACCAAACGATGACGTGTCGCTGctgcaacaaatatttcaacaccTACAAGAACTTTATGGCCCACGTACGCAAAAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATATCGCATCTAAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTGAACGCATTGCGCATCAAGCAGCCGAACTTTTCACATGCCAATGCATCTGGCCTGGCTGTGACAGCCGACggacagcatcaacagcagatGATTGTCGGCGGTGAAGCGTCAACCGAACGGCCGGAAAAACTGCGCGCCAAGGAGCTGCTGGTTAACAAACTGTACGAGTGCAAACTGTGCCCGAAGGGCTTTCGCACCAAGCACGAGTTTCGCACCCATGTGTATGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGTCTGGACTTTGCCGATCCGGTGGATCGGCGTCGCCATTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACCTGCGATGCCAAATTGGAGACGCATCAGCGCTTCCTCGATCATGTCTATCAGGATCACTTGGGCGGCGTTGGCAGCGACAATGCCTCCACAGCGAACAGCGGCGGACTCGACCATTCGCCCGGCAAACGCAGCCTCCTGGGCGCCCTCGGCATCGGTGTCAGTCAGTCCTCCAATGAGGAGTCGCGCAGCAGCGGccatcacaacaacaatgcgtcTGAGGCGCCGCTCACCTCGACACCGAAACTAACTGCAGCTGGACTCGGagggacagcagcagcaacagcagcaacgggtgcagcagcagcgactagCGGCGGTTCCACATCGGGGAATCGTGATGCGCCCAAATCGCAGTATTTTTCGCGTATGCCGCAGGTTTGCCCGATCTGTGGACAACAgtacaacaactataacaatgTGCTGCGGCACATGGAATCGAAGCATCCCAACAAACTGCCAGAGACGTACAAGTGTGTCCGGTGCGGATTGGGCTATCCGCGAATCTCGTACCTGCGCGAGCACATGATCAATGTCCATGGCGTGGACAAGAATCGTCACTCGGGCGGCTTTGAATATATTGTCAATGCCGATGCGGTTAAGTTGGCCGATGGCAGCACGCCAAACGTTTATACCGGACGCTACGACTACGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgATGACGATGAGGAGGAGGGCGGCAGCATTGCCAAGAAGATGCGATTggacgacagcagcaacaacagcagcatcaacatgaGCCTGGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGtgttcagcaacaacatcggCCTCTCCAATCACATGCGGTCCCATTACACAGCCTCAACGGCGACGAGCGCCGCTCTGGCGGCGGCCAATCGGATGACGCCCAAATCGCTGACAATTACCGCAACGCCGCCGCTGGAAGCGGCTGTGGTTTCGTcgacatcagcatcagcacctgccacaacaacagcagcagctgcagttgtagcaacaactgcaacagcagcagcagcaacaacagcaacaacaacagcagcagcagcagcagctggtggcaATTTGCCGCCCGCGATGGCAAATCAAACGCCACAGGAGCAGGCGGTATTCCGGCGCAGTCTCGATCAGGCGGCCGATCGTCGCTTCCGGCGGATGCGTTGCCGCATCTGTCAGCGCAGATTCAGCTCAAAGAAATCGTATCGTTATCACATGCTGACCGATCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTTGCCTACGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGACGCGCCATCAAGGACGAGATGATTGTCAAGCAATTCGAGTGTGATATCTGCTCCATTGTCTACAGCAACGAACtggaactgcagcagcacaagcGCAGCGTGCACAAATCCCACTCTGGCTCGGCGGCCAGTGATTCCAACAAGTCCGTTAAATCAGCTACAGCTACCGCTACCTCAGCCGAACTGGCCGAGACATCCGGGACGGCTGTAACAACGTTGCCCCTCTACTGGTACCAGTGCAAGTACTGTCCATCCAATttcaacaccaacaaaaaactggCCATTCACATCAACTCGCACGATGAGTTCGACTCCAACGACTACTCCTGCAAGGACTGCGGCAATGTCTACAGTGGCCGCAAGAGCCTCTGGGTGCATCGATATAAGAAGCATCCTCAGGTGCCCGATCCCGCTGAGTGCAATCTGTGCCGGAAGATGTTCTTTGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCGATCACTGCCACCGGCGCCCATCAGcaggatcagcagcagcaacaactgcagcagcagcaacagcatcagcgtGGCATCTTCAAGCACAAGACgggcgatgatgatgaggaggaggatgatgatcatcagctgctgctgctggacgatGGCATCGGCGGCGATAGCAATGGTGGCAATGCCATGGGAGCGACTGGCAATCCGAGCACGATCAGCGCGAGCACGCTGAAGATACGGATACCGGAGGTGGCGTGCACAATTTGCGGTGCTCGATTCACCGATCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGATTTGTATGTGGACAACCCGTTGGCGGCCATGTTCGATGATGGACCAGCGGACGCTGGACAATTTCAGGTGGAGCGTCAAAACGAGAACGGCGAATACGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCAATCATCGACGGCGAAGCGACAACgctgaacaacagcagcagcaacaacagcagcagcaacaacaacaacaacaacaacaacaacaattcaatgCTGCATCTGCGCGAACTGCATGCGGTGGGTCTGATGCCCAACCAGCAAcaccagaaacaacaacagctgcagctgcaacagcagcaacagcagcagcggaacaACACGTCGGGCAGTTCGAGCAAATCGCTGAAACGGAAACGTGAACTGAAATGCGATTACTGCGCCTCCACAttcatcagcaacaacaatctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCCACCTGCCAGAGCCGCCAGTGATTGAGGTGGACGAGCCGCTGACCTGTCGCCGGTGCGGTGATCTGCGGTTCGAGACAAAGGAGCTGTGGATCGAGCATAAGCTGGCCGATGCGAAGGTGGTCCGTCCGTTCTGTCCGTTTCAATGGGGCTGCGATCTGTGCGGCGAGTATTTGTCGCGCAAGGAGAAACTGATCAATCACATCAACAATCATCTCAAGGAGGATGTGATTGTGCCTGTTGCAGTGGCTGTTGCCAAATCAGCGCCGAAcaaaaatacagcaaaaacaacagcggcagcaacaacaacagcggcagcaacaacaacatcagcagcagcaacaacagcagcagcagcagcggcaacaaccaCAAAGGCAACAATCAAAACGAAggccaaacagcagcaggaagagGGGGCGCAGTCGGAAATGGAGAGGGAGGCGCAGGTGGAACTAAATGCTGGCAAGCTGGCAAAGCAGGAGGATGATAGTGATATGGATGATAGCGATAGTGGGGATGATGAGGATAGCACAAGTGctggcgatgatgatgacgatgatgatgatgacgatgaggatgacgatgatgatgacgatgatgatgatgatgaagatgatgatgaagacGAAGATGttgtgcagcaacagcagctgctgcagcagaaacaacaacaacaacaacagcagcagcagcagcagccgcttagcagcaacaacaataacaataataataacaacaacaacaacaacaccacgaGTGTTGTGGCCAACGATGATATCGATGATCTCATTGAGGAGGTCATCGAGGTTGATGGCATGGTCGAGGAACTGGACGATGATgaggacgatgacgacgatgacgatgacgatgatgacgatgtgGATGAAGTCGATGACGACGATGGCAACACCACAGATGAGCACCAGCAGCTGTCAGCCGCCAATGACAAGCAGCAGACGGAGCAGCGGGCGCAGCGGGAACAGCATCAGCCGCGACGACTCAACTTTGACTACAGCCGCACGGATAGCGCCAAGCTGAATGGCACCGGTAAACAAACGCTGGCAAAGTCAaagggacagcagcagcagcagcagcagtcggtTTTGGTCATGCACAGTTCCGAGGAGGATGATGAGGAGGacgatgatgttgatgatggtgtggatgatgaggatgaggatgcgGGCGGTGTTGGTGAGGCAATGACCATCGATGATATTATTGAAGAGGACGATGgtgaagatgatgatgatgatgacgatgatgacgatgacgatgatgtgGTTGGTGTCGGTGGTGCTGTCGTTgaggatgatgatgttgaCGAAGACATGGACGAGGACGATGTCGACGATGTCGATGACGACGAtatcgatgatgatgacgagcACATTGGCAACGGCGATGCACACAACAATGCGGCGCAAACCAGCGCCAGCGTTGTTGATGCCGATGCGGATGGGGATGGTggcacatcatcatcatccgaGAGCGagtcgacagcaacaacatcgcaGTCAATTGgagctgctgcagtcaCATATTAA
Protein Sequence: MCDTVVTTVAAGTGTVTATGTGTGTGAAGAADTAATTTAMEERTRKSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLETDKSKQQTLLGYLDLNKTENGSSTDHQQQHHELKNDSATAAAEKASANILDGIPSLKKRKSLTVYPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAATLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGYDYDSPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRIKQPNFSHANASGLAVTADGQHQQQMIVGGEASTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGSDNASTANSGGLDHSPGKRSLLGALGIGVSQSSNEESRSSGHHNNNASEAPLTSTPKLTAAGLGGTAAATAATGAAAATSGGSTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEGGSIAKKMRLDDSSNNSSINMSLANQQKECLICNAVFSNNIGLSNHMRSHYTASTATSAALAAANRMTPKSLTITATPPLEAAVVSSTSASAPATTTAAAAVVATTATAAAATTATTTAAAAAAGGNLPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSNELELQQHKRSVHKSHSGSAASDSNKSVKSATATATSAELAETSGTAVTTLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECNLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQLQQQQQHQRGIFKHKTGDDDEEEDDDHQLLLLDDGIGGDSNGGNAMGATGNPSTISASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSNNSSSNNNNNNNNNNSMLHLRELHAVGLMPNQQHQKQQQLQLQQQQQQQRNNTSGSSSKSLKRKRELKCDYCASTFISNNNLRRHMYELHKHEVSHLPEPPVIEVDEPLTCRRCGDLRFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAVAVAKSAPNKNTAKTTAAATTTAAATTTSAAATTAAAAAATTTKATIKTKAKQQQEEGAQSEMEREAQVELNAGKLAKQEDDSDMDDSDSGDDEDSTSAGDDDDDDDDDDEDDDDDDDDDDDEDDDEDEDVVQQQQLLQQKQQQQQQQQQQQPLSSNNNNNNNNNNNNNTTSVVANDDIDDLIEEVIEVDGMVEELDDDEDDDDDDDDDDDDVDEVDDDDGNTTDEHQQLSAANDKQQTEQRAQREQHQPRRLNFDYSRTDSAKLNGTGKQTLAKSKGQQQQQQQSVLVMHSSEEDDEEDDDVDDGVDDEDEDAGGVGEAMTIDDIIEEDDGEDDDDDDDDDDDDDVVGVGGAVVEDDDVDEDMDEDDVDDVDDDDIDDDDEHIGNGDAHNNAAQTSASVVDADADGDGGTSSSSESESTATTSQSIGAAAVTY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547496; iTF_00588979; iTF_00598302;
90% Identity: -
80% Identity: -