Drel005705.1
Basic Information
- Insect
- Drosophila repletoides
- Gene Symbol
- -
- Assembly
- GCA_018150835.1
- Location
- JAECWQ010000221.1:9907893-9914517[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 1.4e-05 0.00097 19.4 2.1 1 23 109 131 109 131 0.97 2 18 4.6e-06 0.00032 20.9 0.4 1 23 137 159 137 159 0.97 3 18 0.00068 0.047 14.1 0.9 1 23 165 187 165 187 0.95 4 18 9.8e-06 0.00067 19.9 3.1 1 23 193 215 193 215 0.97 5 18 2.2e-05 0.0015 18.8 4.7 1 23 221 243 221 243 0.99 6 18 4.1e-05 0.0028 18.0 5.7 1 23 249 271 249 271 0.97 7 18 2e-07 1.4e-05 25.2 4.3 1 23 277 299 277 299 0.98 8 18 7.1e-08 4.9e-06 26.6 2.4 1 23 305 327 305 327 0.97 9 18 4.1e-05 0.0029 17.9 6.7 1 23 334 356 334 356 0.97 10 18 7.2e-05 0.005 17.2 6.5 1 23 362 384 362 384 0.98 11 18 6.4e-06 0.00045 20.5 4.5 1 23 390 412 390 412 0.98 12 18 4.7e-06 0.00032 20.9 8.1 1 23 418 440 418 440 0.98 13 18 3.8e-06 0.00026 21.2 7.6 1 23 446 468 446 468 0.97 14 18 4.3e-07 2.9e-05 24.2 7.7 1 23 474 496 474 496 0.98 15 18 0.00013 0.0092 16.3 9.5 1 23 502 525 502 525 0.95 16 18 4.7e-05 0.0033 17.8 0.9 1 23 531 553 531 553 0.98 17 18 0.00052 0.036 14.5 3.4 1 23 563 585 563 585 0.97 18 18 5.9e-06 0.00041 20.6 1.6 1 23 591 614 591 614 0.96
Sequence Information
- Coding Sequence
- ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTAACAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCACCACCCTTGCCACTTACAGGCAAATCAGGCGGAGAACATATTAATAAGAAAGACGGCAGCGGCGGACAACCGCCGCATCACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAATTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCACGGCACACCCGATGGCACGCCGATTGCAACGGGCACGCATGTTTGCGATATTTGTGGCAAAATGTTTCAATTCCGTTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGTAAGCCGTTTATGTGTCAGGTATGCGGTCAGGGCTTTACCACATCCCAGGATTTAACCCGTCATGGCAAAATCCATATTGGCGGACCAATGTTCACCTGTATTGTATGCTTCAATGTTTTTGCAAATAATACGAGCCTGGAACGCCATATGAAACGACATTCAACGGATAAACCATTTGCCTGTACCATATGCCAAAAGACATTTGCACGCAAAGAGCATCTGGATAATCATTTTCGTTCCCATACCGGTGAGACACCGTTTCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTGAATCATGTGCGAAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCATACAAACGAGACGCCGTTCCGCTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACACGAAAGGAGCATTTGTTAAATCACGTTAGGCAGCATACGGGAGAGTCGCCCCATCGCTGTTCATATTGCATGAAGACGTTCACACGAAAGGAGCATCTGGTTAATCATATAAGGCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTTACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGTACGAAGACGTTTACACGAAAGGAGCATCTCACGAATCATGTCCGACAGCATACGGGCGATTCGCCACATCGTTGTAGCTACTGCAAGAAGACCTTTACCCGGAAGGAGCATCTGACGAATCATGTACGGTTGCACACTGGAGACTCACCCCATAAGTGTGAATATTGCCAGAAGACGTTTACCCGGAAGGAGCATCTCAATAATCATATGCGCCAGCACTCAAGCGATAATCCCCATTGTTGCAATGTTTGCAATAAGCCCTTCACTCGCAAGGAGCATCTGATCAATCATATGTCCCGCTGCCACACCGGTGATCGCCCGTTCACCTGTGAGACATGCGGTAAATCCTTCCCCTTAAAGGGAAATCTTCTATTCCATCAGCGTAGCCACACCAAGGGTCAGGAATGCGAGCGCCCCTTCGCTTGCGAGAAGTGTCCGAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGGGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAAGTGAGTCGGACACAAAAATAAATACTTAA
- Protein Sequence
- MQHVSAASSAPSVVTAPVVTTGGGTTITLGGPPPLPLTGKSGGEHINKKDGSGGQPPHHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGTPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIISESDTKINT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00599004;
- 90% Identity
- iTF_00599004;
- 80% Identity
- -