Basic Information

Insect: Drosophila repletoides
Gene Symbol: ftz-f1
Assembly: GCA_018150835.1
Location: JAECWQ010000220.1:1510783-1513470[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 3 1.7e+04 -7.1 12.2 42 175 26 149 9 199 0.38

2 4 3 1.7e+04 -6.4 11.1 29 114 155 242 147 290 0.68

3 4 1.1e-18 6.5e-15 55.4 0.4 1 82 446 526 446 554 0.77

4 4 3.1e-70 1.8e-66 225.2 0.5 156 408 606 851 571 853 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	3	1.7e+04	-7.1	12.2	42	175	26	149	9	199	0.38
2	4	3	1.7e+04	-6.4	11.1	29	114	155	242	147	290	0.68
3	4	1.1e-18	6.5e-15	55.4	0.4	1	82	446	526	446	554	0.77
4	4	3.1e-70	1.8e-66	225.2	0.5	156	408	606	851	571	853	0.91

Sequence Information

Coding Sequence: ATGGATAGTTTTAATATACCTTTGTTGGCCGAGAGCAGCAGCATTGTTGGTAGCTATGCAACTAACAACAACAATAACCAGCAACAGCAGGAACAACAACACCTGCAACCCCAACACCACCAACAACAGTTGCTGTCGCATCATCAGAAGGATCAAATGCTTGCCGCTGGTAGCACACCCCTCATGCCTTTTATCAACTATCAGCCATTGCAAAAGGATACACAACACAATCCCAATTCTAATCCTGCGGTGGATAATTTTGCCATTGATGGCAGCCAATTGGATGGTGGCGTCTCTTTGAGTGGTCTCTGTGAACGCATCTTTGCCAGTCCCAATCCCCAGAGCAACAGCAATAATAATAATATGGACGCTAAGCTAACATCAGAGTCATCAATCAGCGGTCCAGTTATACTAGAATCTGTTACAATGCCTTCCTTTCCCAATTCGTCGTTTAGCAACCGCAACAACGAGCACAGCAGCAGCAACAATAATCAGGTTGCTGCCAACTTTGAGAATCATCAGCTGAAGCCATTGCAAAATGGTGTTGCTGCAACAACAACAGCAACAAACACTGCCAATCGTAGAACGCTGCACAGCATTGAAGACCTGGCAGCCAGTTCTTGTGTCACAAACAAAGCAACAACAAATGGCAACAACAGCAATATAAACATCGCAACACAACAGCAGCATCAACAACCACAACCACAACAACAACAACAGCAGCAACAAGAGACTGACAACCTGAGCGGCTCTAACCTCAGCTCTGAAGATGAGTCCATATCTGAGGATGAATTTGGTCTAGAGATTGATGATGAGGGGGGCTATCAGGAGACGAGTTCATCGCACGCACAACAATGTGGCAATGGCGCTACGGGTGGTGGCAATCCTGCCACAACGGGTGGAAGTTCTACGGTCAACGGTTATATGTTATTGGCAACAAATTCTGGCGGCACTTCAGCTGCCTCTGCGGCCGCCCATATGTCTGGCTTAGGGCGTGGCTTTGGGGGTGCGAGTGGCATTAATGTCGCTCCTGGCGGTGGAAAAGATGGCCATAATGTCGGTATCAGCGCCAGCTCTGGCAGAGACGGTGGCGAAGCCATCGCTTTCAAGCATCTCTTCGAGGAGCTGTGCCCTGTCTGCGGGGATAAGGTAAGTGGCTATCATTATGGCCTGCTCACCTGTGAATCCTGCAAGGGATTCTTCAAGCGCACCGTTCAGAATAAGAAGGTCTATACTTGCGTCGCGGAACGATCCTGTCACATCGATAGGACCCAACGCAAACGTTGCCCATATTGTCGATTCCAAAAGTGCCTTGAGGTGGGCATGAAACTGGAGGCTGTTCGAGCGGATCGCCTGCGTGGAGGTCGGAATAAGTTTGGACCGATGTACAAGCGAGATCGGGCGCGAAAACTTCAGGTGATGCGTCAGCAGCAGTTGGCATTGCATGCTCTGCGCAGTTCTATGGTGACGGAAATGAAGCCAACGCCGCATTTGCAGGGCTATCAGCAAGCATATCCAAATATGAATATTAAGCAGGAAATACAAATACCTCAGATATCCTCAGTCACACAGTCGCCGGATTCGTCGCCCAGCCCTATTGCCATTGCCTTGGGCAGCGGAGCTGGTGGAGACGGAGAAGGACGCAGCAACGCCGGCGTCGGAGGTGGCGGAGGAGCAGGAACTGGCAGCAACAACAACAATGGAACCGATGGTTTTCAACGCAACGGAAACAGCAACAGCAGATGCCACGAAACTGGAACTGGACCTCTGCAGAATTCAGGCGCATCCAAATTGTGCTTCGATTCTGGCAAACATCAATCGAGCACAGGCTATGCGCTTGTGGAGCCGCTGAGGATATCGCCCATGATTCGTGAGTTCGTGCAATCGATCGACGATCGGGAATGGCAGACCCAGCTTTTTGCGCTGCTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTGATGTGCAAAGTGCTCGATCAGAATTTATTCACACAAGTCGATTGGGCACGAAACACGGTTTTCTTTAAGGGTTTGAAGGTGGACGATCAAATGAAGCTGCTGCAGCATTCATGGTCCGATATCCTTGTACTGGACCATCTGCATCATCGCTTACATAACAGTCTGCCAGATGAGACGCAACTAAATAATGGTCAGGTCTTCAACCTGATGAGCCTGGGCCTTTTGGGTGTTCCTCAGTTGGGTGACTACTTCAATGAACTGCAGCATAAGCTGCAGGATCTGAAATTCGATATGGGCGATTATGTTTGCATGAAATTCCTAATTCTCCTTAATCCCGATGTGCGCGACATTGTCAACAAGAAAAACGTCTTGGAGGGGTACGAAAATGTGCAGGCAGCTCTGCTAGATTACACGCTTACGTGTTATCCTTCAGTTAATGATAAATTCCGGAGGCTATTGAATATTATACCGGAAATCCACGCGATGGCCGCAAGGGGTGAGGATCATCTGTACTCGAAGCATTGCGCTGGCAGTGCGCCGACGCAGACGCTGCTAATGGAGATGCTCCATGCCAAGCGGAAGGTGTAA
Protein Sequence: MDSFNIPLLAESSSIVGSYATNNNNNQQQQEQQHLQPQHHQQQLLSHHQKDQMLAAGSTPLMPFINYQPLQKDTQHNPNSNPAVDNFAIDGSQLDGGVSLSGLCERIFASPNPQSNSNNNNMDAKLTSESSISGPVILESVTMPSFPNSSFSNRNNEHSSSNNNQVAANFENHQLKPLQNGVAATTTATNTANRRTLHSIEDLAASSCVTNKATTNGNNSNINIATQQQHQQPQPQQQQQQQQETDNLSGSNLSSEDESISEDEFGLEIDDEGGYQETSSSHAQQCGNGATGGGNPATTGGSSTVNGYMLLATNSGGTSAASAAAHMSGLGRGFGGASGINVAPGGGKDGHNVGISASSGRDGGEAIAFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDRTQRKRCPYCRFQKCLEVGMKLEAVRADRLRGGRNKFGPMYKRDRARKLQVMRQQQLALHALRSSMVTEMKPTPHLQGYQQAYPNMNIKQEIQIPQISSVTQSPDSSPSPIAIALGSGAGGDGEGRSNAGVGGGGGAGTGSNNNNGTDGFQRNGNSNSRCHETGTGPLQNSGASKLCFDSGKHQSSTGYALVEPLRISPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFTQVDWARNTVFFKGLKVDDQMKLLQHSWSDILVLDHLHHRLHNSLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQHKLQDLKFDMGDYVCMKFLILLNPDVRDIVNKKNVLEGYENVQAALLDYTLTCYPSVNDKFRRLLNIIPEIHAMAARGEDHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00587458;
90% Identity: iTF_00587458;
80% Identity: iTF_00587458;