Basic Information

Insect: Drosophila repleta
Gene Symbol: -
Assembly: GCA_018903745.1
Location: JAEIGN010000233.1:5127278-5131865[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00034 0.022 15.0 0.1 1 23 161 184 161 184 0.96

2 14 0.00019 0.012 15.8 2.3 2 23 233 255 232 255 0.97

3 14 0.0046 0.29 11.5 0.9 1 23 361 384 361 384 0.93

4 14 0.13 8.3 6.9 6.8 2 23 433 454 432 455 0.95

5 14 0.0023 0.15 12.4 0.4 1 23 519 542 519 542 0.88

6 14 2.8 1.8e+02 2.7 0.0 2 14 561 573 560 577 0.82

7 14 0.00065 0.042 14.1 3.3 2 23 593 615 593 615 0.96

8 14 0.0017 0.11 12.8 0.1 1 23 714 737 714 737 0.95

9 14 8.7e-05 0.0056 16.9 0.4 1 23 789 812 789 812 0.93

10 14 0.004 0.26 11.6 1.5 2 23 862 884 861 884 0.95

11 14 0.0072 0.46 10.8 1.0 1 23 972 995 972 995 0.92

12 14 0.13 8.3 6.9 1.5 1 21 1047 1067 1047 1068 0.95

13 14 0.28 18 5.8 0.0 2 23 1111 1135 1110 1135 0.81

14 14 6.5 4.2e+02 1.5 0.4 1 10 1153 1162 1153 1177 0.74

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00034	0.022	15.0	0.1	1	23	161	184	161	184	0.96
2	14	0.00019	0.012	15.8	2.3	2	23	233	255	232	255	0.97
3	14	0.0046	0.29	11.5	0.9	1	23	361	384	361	384	0.93
4	14	0.13	8.3	6.9	6.8	2	23	433	454	432	455	0.95
5	14	0.0023	0.15	12.4	0.4	1	23	519	542	519	542	0.88
6	14	2.8	1.8e+02	2.7	0.0	2	14	561	573	560	577	0.82
7	14	0.00065	0.042	14.1	3.3	2	23	593	615	593	615	0.96
8	14	0.0017	0.11	12.8	0.1	1	23	714	737	714	737	0.95
9	14	8.7e-05	0.0056	16.9	0.4	1	23	789	812	789	812	0.93
10	14	0.004	0.26	11.6	1.5	2	23	862	884	861	884	0.95
11	14	0.0072	0.46	10.8	1.0	1	23	972	995	972	995	0.92
12	14	0.13	8.3	6.9	1.5	1	21	1047	1067	1047	1068	0.95
13	14	0.28	18	5.8	0.0	2	23	1111	1135	1110	1135	0.81
14	14	6.5	4.2e+02	1.5	0.4	1	10	1153	1162	1153	1177	0.74

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCAATGTTTTCAGCCGATTTCGATGAAGGTGATGGTGAGGTGCAGAGCCGTAATAATGGTAATAACGCTCTCGCAGACGAGTTTATGGGTGAAAAGGAGGAGGACGAACAGGCGGCTGAAGAGGATGAGGGCTCGGCCGATGAAAATAGCAGCAAACGAAAAGGACACGACCCTGATGACGATGCCATATTTGATTTTGAGTTAGAGCCTATTGTTAGCATTGCGGAACCAGAACTGGAACCGTTGCCTAGACTACGGGCGGCCCCTCTGCAGCCACCAATGCCAATGGGTCCAGCCGTCCGAGCACAGCACCGTCACTCGTTGCCAGCCTCGTTTGGCTCCCAGCAGATGGTGGGCCGTGGCGGTTCAGGGACACCATCCACACGGCCAACGACCTCTCAAATCAATGCCACCGATGAGAACGGGTTGCCCATCAATTATGAACTGGGGGTTACCTATATATGCCCGGCCTGCGGGGCAGAATATCGACAGCAGGATCTGTGGAAGCGCCACATGAACCAAGTGCATCAGTACAATACTCGACGTGGTCTAAATTTCGTGGCCATTGACAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATCGCGATGCACAGCCGAGAGAATTTGCTTAAACATAAGTTCACCCATTTGCCATTTCGGTGCACCAAGTGCCACATATGCAAACGCGAGTACAAATACAGGCAGGACCTGATGGTACATCTGCGAATGGTGCACTGCGATGAGGTGGTGGCCATGATGCGTGGCGGCAAATTAAGTGCCGGGCGCAAGACGCGTGTTCGCGAACCGCGCATCGATCAGCGCCGCGAACATTATGGACAGGTTCATGACGATGATGGCATAGCGGTCAAGAATGAGCTGATGGACGCGGACGACAATGCGGAACCAGTTGAAGGGTCCAATCATGACTTCGACGATGAACACAGTCTTAGTTCCACTCAAGCGGTTAAGAAAAAGCGTACCACTCCTGGTGCACTCAATGGAAGCGTGAATGACAGCGGTGCAGCGGATATTTGCGAGGACTATATACACTACATGTGTCCGGACTGTGGCACCGATTGTGAGACGCACGCCCAATGGAATCAGCATATTGAATTTGTACACGACTACGTCAGTCGAAGGGGCCTGAACTTCCGTTGCGTGGATATGCAAATGCAGTGCCTCGAGTGCGAGGAGTTTGTCATTCCGAACACGATAAAAACGCTGCGCGCTCATAAGTTTGGCCACTTGCCACAACCGGAGTGGATGCGCTGCAAGCTGTGCTATCAGGGCTTCACAGAACATCATGAACTCCGAACACATCTTCTTAAACATCATCATTTGGAAACCTTAATGCCTGAGAAGGAAGAGGAGGAGCAGCAGTCTGTTGCCATATCCGGCGTGGGTGATGAGAATGAGGGTAATCCTGGTACTGTCTGCGATGATGAAACTTCATTGCATTGGGATGATGTGCCTCGTCGTGGTGGTCGCATTGGGAGCGATGATATATACGAGCCACATATTGATTACCTATGTCCGCAGTGCGGCAAAGAGTTCATAGAAAAAAAACATTGGCGCATGCATGTTGTCCAAGTGCACGGCATGAATGATCTGACCAAGTTGAACTTCGAGGTGATCAGCGATATCCAGTTGAGGTGCACCGAATGCGATAAGATAATAACGAATGCATATGGCATACAGAATGCTCAGCAACACAGGACGACGCATTTGCCCTACAAAGCGTACGCAAGGTGCCGCAAATGCCATAAGTCCTATACAGATCGCAAGGGTCTCGTCAAGCATTTGGCTACATACCATCGCGTGGGTTACGAGTCGCGTAAAACGGTCGGAACAGGCGCTGCCAATTTGACGCCAACCAAATTACAGACGCCACGCAGGCAAATTGTCACAGTTGCAAATGAGACTTACGAGATTATCTATTTGGACGAGGATCAATCGCCGCCTAGCAATAATAATTTAAATGAAGAGAATGATTTTGGCGAGCAAATGCAAGCGGACGATGATGATTATGCAGTAGGTAGCACAAGTGGTTTGATGGGACGCCAGCCGCAAGCAGCTACTGCTGCTGCGCCCAATCCTAACACCAATCGTTATAAGTGCGTAGATTGCGGATCGCTCTTTGCCACACAGATGGCGTTAAAGACGCACATCAGCGAGGAACATGATTTTATGGACACACAATACAGCGAGAGAAAATTTGACGATGCTGAGCCCACGGAGGAGGCTGCTGCAGTGCCAGTTGCCGTTTCAACCATTGCAGGTAATACGCCTGTAAAGAACACCTCAGGCGCCTCCACTATTGAGCAGAACTATATATTCCTGTGCCCGTCGTGCGGCAAGGCCTACAAGACGCAGTTCGAGTGGCGACGCCACATCAACGAGCAGCACAATTTCGATAAACGGCAGTATTTAAATATGCGCCAGCTGGACAAATATCGCTATCAGTGCACCCTTTGCAAAGACATTGTATGCAATTCAAAGCTGAAAGGCCTGCAGGATCATCATTTTCGTCATTTGCCTTACCGGCTGTATTTGAAGTGCCTGGTGTGCGGCACCTGCTATAATCACAAACCCAACATAGCTGCTCATCTCCGCGCGCGACACAACATCTATGAGCGCGAGTCCTCATCTTGGCGTGAGCAGCATCAAAAGACCCAGAATGGTGACGAGCAGCCTAAGTATAAGGACAAGGATAGGGATACGCAAGTTGCTGTTGCCACTGGCACTACTTCTCCTTCACCTACGCCCGGCAGTAGTCGCACACTCAAGCCACAGCCGGGCGTGCTGCCCACGCGACCCGCAGGACTCAACACATTGGAGGATAGCATATCGTATCACAATGCAGTAGATCTGGACTTTATTACCTACTATTGTCCCAAGTGCAATATGAACTTTGACTCGCACGCCTTTTGGCGCAAGCATATTGTCGAGGTACATAACTATAATAGTCGACAAGGCCTGAACTTTCGCCAGATTGACAACCATCACTATCTGTGCCTGGAATGCTATAAGCGTGTGACTGTGACGCACACTAAGGGCGCCATTGGGCAGCTACAGTCGCACAAGTTCCGGCACTTGCCGTATCGCTCCTTCAAGTGCTTGACCTGCAGCGGGGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCACTTGAACCGCGACACCAATCGCTGCGATAATAAGCCATTAAGTGGCCAGGAGAATGATGAGGATACAACGGATCAGCCGGACAGGCCAGCTACCTTGGGGTCGAAAGAGACACTCGATGTCGCGACTTACCGTTTGATGTGTCCAGAGTGCGGCGATGGGTTTACCACAAGCAGCAAAGCTCTGTGGCGAGAGCACATTAACATCCAGCACAGTCTGGGGAAGCGGGAGATGCTGCACATGCGCAAGCTAGGCGATGAACTTTATCGCTGTACAGATTGCGAGGAGCAGCTGCAAACGAAGCACCTGCGAGTGCTACAGGAACATCGCTTCCAGCATTTACCCTATGCCGCATATATACGCTGCCAGCTATGCGAACAGCAGTCGGCGGATGGAGTGGGTCATGGTGTAGCCGCTGCGGGATTACATAATATGCGGGAACTGCAACAGCACATACGCAACAAGCATCCGGATGTGATTGAGCAGGACGAGCGAATGCAAGCACTGCTCGACGAGGAGGAGGATAGTCAGCAGCAAGCGGCTAGCGATGAAGCAGCAGACAGTGGACTATATATGCCGCTGCCGCCGCATTTGCTGGACGATGATGTGGAGGACATGGAGTTCGAGGAACAGTATCTGCTAGGTTAA
Protein Sequence: MEGMDLWTSMFSADFDEGDGEVQSRNNGNNALADEFMGEKEEDEQAAEEDEGSADENSSKRKGHDPDDDAIFDFELEPIVSIAEPELEPLPRLRAAPLQPPMPMGPAVRAQHRHSLPASFGSQQMVGRGGSGTPSTRPTTSQINATDENGLPINYELGVTYICPACGAEYRQQDLWKRHMNQVHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCHICKREYKYRQDLMVHLRMVHCDEVVAMMRGGKLSAGRKTRVREPRIDQRREHYGQVHDDDGIAVKNELMDADDNAEPVEGSNHDFDDEHSLSSTQAVKKKRTTPGALNGSVNDSGAADICEDYIHYMCPDCGTDCETHAQWNQHIEFVHDYVSRRGLNFRCVDMQMQCLECEEFVIPNTIKTLRAHKFGHLPQPEWMRCKLCYQGFTEHHELRTHLLKHHHLETLMPEKEEEEQQSVAISGVGDENEGNPGTVCDDETSLHWDDVPRRGGRIGSDDIYEPHIDYLCPQCGKEFIEKKHWRMHVVQVHGMNDLTKLNFEVISDIQLRCTECDKIITNAYGIQNAQQHRTTHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYESRKTVGTGAANLTPTKLQTPRRQIVTVANETYEIIYLDEDQSPPSNNNLNEENDFGEQMQADDDDYAVGSTSGLMGRQPQAATAAAPNPNTNRYKCVDCGSLFATQMALKTHISEEHDFMDTQYSERKFDDAEPTEEAAAVPVAVSTIAGNTPVKNTSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEQHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIYERESSSWREQHQKTQNGDEQPKYKDKDRDTQVAVATGTTSPSPTPGSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNMNFDSHAFWRKHIVEVHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTNRCDNKPLSGQENDEDTTDQPDRPATLGSKETLDVATYRLMCPECGDGFTTSSKALWREHINIQHSLGKREMLHMRKLGDELYRCTDCEEQLQTKHLRVLQEHRFQHLPYAAYIRCQLCEQQSADGVGHGVAAAGLHNMRELQQHIRNKHPDVIEQDERMQALLDEEEDSQQQAASDEAADSGLYMPLPPHLLDDDVEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00532646;
80% Identity: -