Drep002867.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila repleta
Gene Symbol
-
Assembly
GCA_018903745.1
Location
JAEIGN010000233.1:2969414-2974060[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.0034 0.22 11.9 1.1 1 23 219 241 219 241 0.96
2 26 0.041 2.6 8.4 2.0 1 23 247 269 247 269 0.97
3 26 0.27 17 5.9 0.8 2 20 301 319 301 322 0.94
4 26 0.0024 0.16 12.3 0.7 1 23 399 422 399 422 0.94
5 26 1.8 1.1e+02 3.3 5.4 1 23 432 456 432 456 0.93
6 26 1.5 95 3.6 0.5 1 19 462 480 462 483 0.84
7 26 0.79 51 4.4 1.6 2 23 497 518 496 518 0.97
8 26 0.0068 0.44 10.9 1.8 1 23 598 621 598 621 0.95
9 26 0.0034 0.22 11.8 0.1 1 22 630 651 630 651 0.96
10 26 0.019 1.2 9.5 3.0 1 23 660 683 660 683 0.98
11 26 0.00079 0.051 13.9 0.2 2 23 715 736 714 736 0.97
12 26 4.4e-05 0.0028 17.8 5.7 1 23 744 766 744 766 0.99
13 26 0.022 1.4 9.3 3.3 1 23 914 936 914 937 0.94
14 26 1 65 4.1 1.6 3 22 946 965 945 965 0.92
15 26 0.22 14 6.2 0.7 1 23 974 997 974 997 0.90
16 26 0.00015 0.0099 16.1 1.5 1 23 1022 1044 1022 1044 0.97
17 26 0.00013 0.0082 16.3 0.9 1 23 1051 1073 1051 1073 0.98
18 26 0.013 0.81 10.1 0.0 2 21 1100 1119 1099 1120 0.94
19 26 0.014 0.88 10.0 3.6 1 23 1165 1188 1165 1188 0.96
20 26 0.029 1.9 8.9 1.5 1 23 1225 1248 1225 1248 0.94
21 26 0.013 0.84 10.0 3.1 1 23 1276 1299 1276 1299 0.97
22 26 1.2e-05 0.0008 19.5 0.1 2 23 1327 1348 1326 1348 0.95
23 26 4.2e-05 0.0027 17.8 2.9 1 23 1354 1376 1354 1376 0.99
24 26 3.5e-06 0.00023 21.3 2.0 1 23 1382 1404 1382 1404 0.97
25 26 5.3e-08 3.4e-06 27.0 2.4 1 23 1410 1432 1410 1432 0.99
26 26 0.00016 0.01 16.0 0.5 1 23 1438 1460 1438 1460 0.97

Sequence Information

Coding Sequence
ATGTTGCCAACGGATATTTGTCGTACATGCACGCTGTATGATGATAGCTTGCTCCCGCTTGCGACCCACATTGATAAATATGCAAATAAAAGTTTAAATGACATGTTACTCGAGTTGACACAAAATGATCCCCTGCAGGAGCATTCAGACGATAGTCTGCCGCAGCAATTGTGTATGGGTTGCTTGCACAAGTTAGAGGCTGCGTATGCCTTTGTAGTTCAGGCGCGCCAGGCTCGAGAGCAATTGTTGCTGCAGCTGCGCAAGAGCTTGCAGACGCAGTGCTTGGATGAGATGCCAATAGACATTAACCTGCAGCACATCAAAACCGAAACGATCGTTGACCTGCAGCTAACTAACAAAACTAAGAATGAAGAAGACACGGAGGGTGAAGAGAGGGAGATGGCTGCAGTGTCTATTCCCGCCCTGAAGTGGCAGCCAGATAGCAATAGTGAGAGCAATCAAACAGCTGCTGATGACCAGGACGTGGACTGTAAACCCAACATGTTACGACGCAGCTCACGTAAAGCAAAAGGCGGCTCAGACAGCGAAATAGCATCAACATCTCCCCACGGCAATCCCTTGCTAAACGCGAAACGGCGCCGTGGTCGCCCAGCACGTCTACTCAATAAGGAAACTGTCAACGAAGAAGGACGGCATGTGTGCGAGGTGTGTGGAAAGACCTTTTCGTGGTATCGGGACATGCAAAGCCACTCGCGCGTACACTTCGAGCAAGCGACCTTCGTGTGTGACAGTTGTGGCAAGAGTTTCCTGCGCAAAGACAAGTACATGTTTCATCTGCGCTCACACAAAAAGCGTGCAGCCAAGTGTCAGGCCATGGAACTGGGCAGCGAATGGCGTTTCGCTGAGCGCCTCTACAGCTCCGGTCGACTCAAACATGCGGAATGCAAGCTGTGCGGCTTAAAATACCAGCGTATAGGGGAGCTGCGCGAGCATCTGGCGTGCCACAAGAACATTGAGACTTTATCCAAACTGAGTCTAGAGAGTGATGTAATCAGGGAACAGTTTGCCAAAGATCAGCAGCAGCTAGACTTGGCGCTAATCAAGCAACAGTTGTGTGCAGACATTGCCAAAGGGCATGGTCAGCTGGACAAATACTGCTCTGTGGTCAACGCGTACGGATATGAGCTCTGTCTTAGCGATTCGGACGAAGAGGTAGCTGGCCGGTCGCCTGAATACCAGTGTGCGGCGTGCAACATTAACTTCTCGCGCAAATATCGCCTCATGCGACACACCCTGGAGGAGCACACACAGGCGGAAAGAACAGTGTCCTGGCACCGCTGCGATATTTGCCAAATTGGCTTTGTGTGCGCTTATATGTTTGAGCAGCATCAACGCACGCAGTGCCACAACAAACTGAAGCGCTACAGCTGTCCCCACTGCCCTGGCAAATTTATTTGGGTGCAGAACCTGGAACAGCATGCGTGCTCGCAACCTACGAAGCAGCACGACGACCAGCTGCTTCAAAAGCAGTGTTGTCTATGTGATGTCCAATTGAGCAGCATGCTCGAATTACGTACCCATTTGCTAACCCATCAGGATGGACGTAGTGGCATTCATCCAGAGCTGCAGACAACTTTCTTTCGCACCTACTATCCCAATGGCCTTGACTGCAGCTTGTCTGAGCTGAGCGCACGTATTGCCAGCGATTTTAAGGCGGAGGATTATGGGCGATACTTTAATGCCAGAACGAGGAACGGCGAGGAGCTCGATTTCATTGCCTCAGACTCTGAGTTGAGCGAAGGGGACCAGCTGAGCTCTGGCAGTACACTACACATATGTTCCCTATGTGGCGAGACGAACACACGCCTGAGTCAATTGCTCAAGCATCAGCAAAGTCGACATAGTGAGGCGCAAGAAAGATTGCCCTTCGTCTGTGGCGATTGCGACTTGAGTTTTGTAGCTGATTCGCTGCTCCAACAACATCGCCGTCGCGTCTGTGCCAAGCAGAACGCCAACTACCAATGCCAGCAATGCAGTCATCGCTTCTACTGGCTTTCCAATTACGAGCTGCATATGCGTGTGCAGCATGATACTCAATTTGCGTTGCAAGCAGATGTGGCCGATGATCAGGAGGGGCAGTCAAGGATGAGAAGCAAGCCCCAGTCAACAGCGTCCAAGCTGCAGTGCGGCGAATGCGAAAAGGTGTTCGTCTGGCCCAAGGACCTGACGCGTCACAAACGCTTGCACCAGCCGCAGGCTTTGGCACAATACCAATGCTTGCACTGTGAACGCAAGTTCCATCGCAAGGATGGGCTTAAGTCGCACATGCGCGTGCATGGCGATGAGAAAGTGGATGCGATGATGGTCAGTGAGCAAGCTCCCTCCCTGCTGCAGCGCATACCAGTGGTGCTGACCCAACTGTCTCGACCCAATGGCTGCAAGCAAATTCAATGCATGATATGCCTATCGCAGCATACCAAAATCTCTGATCTGCGCACGCATTTGCTAAATCATCAGTATTCCATCAAATTTACAGAGGAGCGGGGCAAGCCGGAAAGCATAGAAAGCATTTCACGTTCTCTATACCCAGAACTAGCCGCACCTTTGGAGCAGCAGCAGCTAATCGAACGCATTCAAAGTGATGTGACAAAACGCGTGGAACTGGAAAGATTCATTTCCATTACCAACGAGGCGGGCATTGAGCTCAGCCTGGAGAGCAGCGAAACGGAAAGCGATTCGGACTCTGCCGAGGCCGACAGGAGCAACAGCGAACTACTCTACAGCTGTGAGCTATGCCAGACAAAGGTTTCGCGAAAGCATCAGCTCTACGCCCATGAGCTGGAGCATCATTCGTGGCAACAGGCGACGCGTGTTTGTAACTGTTGCCAGGCGAGATTCGTAAATGAGCAGCTACTAGAGCATCACTATCGGACGCTCTGTCGCAACGCGCACCGACGATTCTTTTGTCGTAAATGTCCGCTACGTTTCCGCTGGCGCGAGAATCTGAAACTGCACTCGGACGTAGCGCACAACGACGCCAGAGGTGACCAATCGAGCCTGGACCTAAAATTAAACGGGACGCCCTTGTTACCCATCGGAAGTTACGACTGCTCCGCATGTAATCGTAGCTTTAAAATGCAGAAGGATCTCACCAGGCATACTCTGATGCATGGCCAAGAGTCAAGCATTTATCGGTGTCGCTGGTGCGCACGACGTTTTTATCGTCAGGCTAATTTGCTGCAGCACATCGAGCGTCACGGTATTAGCGCCGAGCAGCTGCCATATGCTGAGGCACTGCTGAATGCCAGTCGTCATCCACATGGTCAGAAGGTGATCCAGTGCAAGGTGTGTAACCTGACCTACCCCACTATTGCTGCGCTCCGTAGCCATCTTAAATCGGCGCCAACAGGCACACATCATGAGTTTGGCTCGATGCTCAACTACTCCATTACCAATCAGTTAGGATACGAGCTGCACCTGGAAGACTCGGAAACGGACGAGGACACTAAGCCGCCAGGTACGCCCGCATACTACACTTGTGGCATATGCCAATTGCGCTGCGTCCGCAAGTTCGAGCTGCATCAGCATCAGCAAGCGATGCATCGACTGGAGCGTATAACCGAGGGCTGTGATGCTTGCATCTTTAAAAGCGTTTCAGCAGATCTCATCGCCTATCACCAACGCGTCCTGTGCAATAATAAGGAAAAGCTTTTCAAGTGCTCCAAGTGTGGCTACAAGTTTATGTGGGAAACGAATCTGTTGCAGCACACCCAGTTGCAGCATCCATGCAGCGAAAGTGGCGAAGCGCAGCCGGATGCAAGTTCTTTGTCGGCACAGAAAGTGCCCAGCGGAGAGTGTCAAATATTTCAATGCGGCCAGTGCCCTAGTAAATACAATCGCAAGGATCGCCTCACAGCACATGTAAAGAAATGTCATGTAGCGGAAGCAAGTGGTCCCACTTCTGCGGCAGCGAAGCTTATGAAAACTTCAAGTGGCCCCAAGGAGCAGAAAAGTTTTCTCTGCGCTTTCTGCGGCAAGGCTGTTAGTTCGTCCTCCAATCTAATTATACACATACGTCGCCATACTGGCGAGAAGCCATTTAAGTGCGACTACTGCGACATGGCTTTTCCGCGATCCTCCGATTTGCAGTGCCATCGACGCACCCACACGGGCGAACGGCCGCACATTTGTACCGTTTGCCAGAAGGGCTTTGCCCGATCGTACAAGCTGCAGCAGCACATGCGCATCCACAATGGCGAACGACCGTACAAGTGTACCTATTGTGACAAGAGTTTTACGCAGTCGAATGATCTGACACTTCACATACGCCGGCACACAGGCGAGCGTCCCTATCAGTGCAATACGTGCGGCGAACGTTTCATTCAGGGCACAGCCCTGAAGAATCATCGCCTACAACATGGACATCACGACACGATAGTAGACCAGGTCAAAGATAATTAA
Protein Sequence
MLPTDICRTCTLYDDSLLPLATHIDKYANKSLNDMLLELTQNDPLQEHSDDSLPQQLCMGCLHKLEAAYAFVVQARQAREQLLLQLRKSLQTQCLDEMPIDINLQHIKTETIVDLQLTNKTKNEEDTEGEEREMAAVSIPALKWQPDSNSESNQTAADDQDVDCKPNMLRRSSRKAKGGSDSEIASTSPHGNPLLNAKRRRGRPARLLNKETVNEEGRHVCEVCGKTFSWYRDMQSHSRVHFEQATFVCDSCGKSFLRKDKYMFHLRSHKKRAAKCQAMELGSEWRFAERLYSSGRLKHAECKLCGLKYQRIGELREHLACHKNIETLSKLSLESDVIREQFAKDQQQLDLALIKQQLCADIAKGHGQLDKYCSVVNAYGYELCLSDSDEEVAGRSPEYQCAACNINFSRKYRLMRHTLEEHTQAERTVSWHRCDICQIGFVCAYMFEQHQRTQCHNKLKRYSCPHCPGKFIWVQNLEQHACSQPTKQHDDQLLQKQCCLCDVQLSSMLELRTHLLTHQDGRSGIHPELQTTFFRTYYPNGLDCSLSELSARIASDFKAEDYGRYFNARTRNGEELDFIASDSELSEGDQLSSGSTLHICSLCGETNTRLSQLLKHQQSRHSEAQERLPFVCGDCDLSFVADSLLQQHRRRVCAKQNANYQCQQCSHRFYWLSNYELHMRVQHDTQFALQADVADDQEGQSRMRSKPQSTASKLQCGECEKVFVWPKDLTRHKRLHQPQALAQYQCLHCERKFHRKDGLKSHMRVHGDEKVDAMMVSEQAPSLLQRIPVVLTQLSRPNGCKQIQCMICLSQHTKISDLRTHLLNHQYSIKFTEERGKPESIESISRSLYPELAAPLEQQQLIERIQSDVTKRVELERFISITNEAGIELSLESSETESDSDSAEADRSNSELLYSCELCQTKVSRKHQLYAHELEHHSWQQATRVCNCCQARFVNEQLLEHHYRTLCRNAHRRFFCRKCPLRFRWRENLKLHSDVAHNDARGDQSSLDLKLNGTPLLPIGSYDCSACNRSFKMQKDLTRHTLMHGQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKVIQCKVCNLTYPTIAALRSHLKSAPTGTHHEFGSMLNYSITNQLGYELHLEDSETDEDTKPPGTPAYYTCGICQLRCVRKFELHQHQQAMHRLERITEGCDACIFKSVSADLIAYHQRVLCNNKEKLFKCSKCGYKFMWETNLLQHTQLQHPCSESGEAQPDASSLSAQKVPSGECQIFQCGQCPSKYNRKDRLTAHVKKCHVAEASGPTSAAAKLMKTSSGPKEQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQHGHHDTIVDQVKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509945;
90% Identity
iTF_00568387;
80% Identity
-