Dpar012656.1
Basic Information
- Insect
- Drosophila paranaensis
- Gene Symbol
- -
- Assembly
- GCA_035047545.1
- Location
- JAWNPL010000173.1:17003424-17008070[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 25 0.0012 0.081 13.4 1.4 1 23 220 242 220 242 0.97 2 25 0.046 3.1 8.4 2.0 1 23 248 270 248 270 0.97 3 25 0.017 1.1 9.8 0.1 2 23 302 323 302 323 0.96 4 25 0.0035 0.24 12.0 0.7 1 23 400 423 400 423 0.94 5 25 2.6 1.8e+02 2.9 0.5 1 19 463 481 463 484 0.83 6 25 2.6 1.7e+02 3.0 0.8 2 23 498 519 497 519 0.96 7 25 0.012 0.79 10.3 1.8 1 23 599 622 599 622 0.97 8 25 0.006 0.4 11.2 0.1 1 22 631 652 631 652 0.96 9 25 0.012 0.8 10.3 0.8 1 23 661 684 661 684 0.98 10 25 0.00089 0.06 13.9 0.2 2 23 716 737 715 737 0.97 11 25 1.4e-05 0.00097 19.5 5.7 1 23 745 767 745 767 0.99 12 25 0.039 2.6 8.7 3.3 1 23 915 937 915 938 0.94 13 25 1.1 76 4.1 1.6 3 22 947 966 946 966 0.92 14 25 0.24 16 6.2 0.7 1 23 975 998 975 998 0.90 15 25 0.00017 0.012 16.1 1.5 1 23 1023 1045 1023 1045 0.97 16 25 0.00047 0.032 14.7 0.7 1 23 1052 1074 1052 1074 0.98 17 25 0.023 1.5 9.4 0.0 2 21 1101 1120 1100 1121 0.94 18 25 0.015 1 10.0 3.6 1 23 1166 1189 1166 1189 0.96 19 25 0.0072 0.49 11.0 0.9 1 23 1226 1249 1226 1249 0.96 20 25 0.015 0.99 10.0 3.1 1 23 1277 1300 1277 1300 0.97 21 25 1.4e-05 0.00095 19.5 0.1 2 23 1328 1349 1327 1349 0.95 22 25 4.8e-05 0.0032 17.8 2.9 1 23 1355 1377 1355 1377 0.99 23 25 3.9e-06 0.00027 21.3 2.0 1 23 1383 1405 1383 1405 0.97 24 25 6e-08 4e-06 27.0 2.4 1 23 1411 1433 1411 1433 0.99 25 25 0.00071 0.048 14.2 0.3 1 21 1439 1459 1439 1463 0.91
Sequence Information
- Coding Sequence
- ATGTTGCCGACGGATATTTGCCGTACATGCACTCTATATGATGATAGCTTGCTCCCGCTTGCGACTCACACtgataaatatgcaaataaaagtttaaatgaCATGTTACTCGAGTTGACACAAAATGATCCCCTGCAGGAGCATTCAGACGATAGTCTGCCGCAGCAGTTGTGTATAGGTTGCTTGCACAAGTTGGAGGCTGCGTATGCCTTTGTAGTCCAGGCGCGCCAGGCTCGagagcaattgttgctgcagctgcgcaatAGCGTACAGACGCAGTGCCTGGATGAGATGCCAATAGACATTAACTTACAGCACATCAAAACCGAAACGATCGTTGACCTGCAGCTAACTAGCAAAACCAAGAATGAAGAAGATGACACGGAAGGTGAAGAGAGGGAAGTGACTGCTGTGTCTATTCCCGTCCTGAAATGGCAGCCAGATAGTGATAGTGAGAGCAATCGGACAGCTGCAGATGATCAGGAGGTGGACTTTAAACCCAAGAAGTTACGACGCAGCTCACGTAAAGCAAAAGGCGGCTCAGACAGCGAAATAGCGTCAACATCTCCCCATGACAATCCCTTGCCAAACGCCAAACGGCGTCGTGGTCGCCCAGCACGTCTACTCAATAAGGAAACTGTCAATGAAGAAGGACGGCATGTATGCGAGGTGTGCGGAAAGACCTTTTCGTGGTATCGGGACATGCAACGCCACTCGCGGGTACACTTCGAGCAAGCGAACTTCGTGTGTGACAGTTGTGGCAAGAGTTTCCTGCGCAAAGACAAGTACATGTTTCATCTGCGCTCGCACGAGAAGCGTGCAGCCAAGTTTCAGGCCATGGAACTGGGCAGCGAATGGCGTTTTGCTGAGCGGCTCTACAGCTCCGGTCGACTCAAACGTGCGGAATGCAAGTTGTGCGGCTTAAAATACCAGCGTATAGGGGAGCTGCGCGAGCATCTGGCGAGCCACAAGAACATTGAGACTTTGTCCAAACTGAGTCTAGAGAGTGATGTAATCAGGGAACAGTTtgccaaagagcagcagcatgtAGATTTGGCGCTAATCAAGCAAAAGTTGTGTGCAGACATTGCCAAAGGGCGTGATCAGCTGGACAAATACTGCGCCGTGGTCAACGCGTACGGATATGAGCTCTGTCTTAGCGACTCGGACGAAGAAGTAGCTGGCCGGTCGCCTGAATACCAGTGTGTGGCGTGCAACATTAACTTCTCGCGCAAATATCGCCTAATGCGACACACCTTGGAGGAGCACACACAGGCGGACAGAACAGTATCCTGGCAGCGCTGTGATATTTGCCAAATTGGCTTTGTGTGCGCTAATATGTTTGAGCAGCATAAGCGCACGCAGTGCCACAATAAACTGAAGCGCTACAACTGTCCCCACTGCCCTGGCAAATTTATTTGGGTGCAGAACTTGGAGCAGCATGCGTGCTCGCAACGAACGAAGCAGCACGACGAGCAGCGGCTTCAAATGCAGTGTTGTCTATGTGATGTCCAATTGAACAGCATGCTCGAATTACGTACCCATTTGCTAATCCATCAGGATGGACGTAGTGGCATTCATCCAGAGCAGCAGGCAACTTTCTTTCGCACTTATTATCCCAATGGGCTTGACTGCAGTTTGTCTGAGCTGAGCGCACGCATTGCCAGCGATTTTAAGGCGGAGGATTATGGGCGATACTTTAATGCCAGAACGGGGAACGGTGAGGAGCTCGATTTCTTTGCCTCGGACTCTGAGTTGAGTGAACTAGACCAGCTGAACTCTGGCAGTACACTACACACATGTTCCCTATGTGGCGAGACGAACACACGCCTGGGTCAATTGCTCAAGCATCAGCAAAGTCGACACAGTGAGGCGCAAGGAAAACTACCCTACGTCTGTGGCGATTGCGACTTGAGTTTTGTAGCTGATTCCCTGCTCAAACTACATCGCCGACGCGTCTGTGCCAAGCAGAACGCCAACTACGAATGCCAGCAATGCAGTCTGCGCTTCTACTGGCTTTCCAATTACGAGCTGCATATGCGTGTGCAGCATGATACTCAAATCGCGTTGCAGGCGGATGATGCCGATGATCAGGAGGGGCAGTCAAGGATGAGAAGCAAGCACCAGTCAACAGGATCCAAGCTGCAGTGCGGCGAGTGCGAAAAGGTGTTCGTCTGGCCCAAGGACCTGACGCGTCACAAGCGCCTGCACCAGCCGCAGGCCTTGGCACAATACCAATGCTTGCACTGCGATCGCAAGTTCCATCGCAAGGATGGGCTTAAGTCGCACATGCGCGTGCACGGCGAACAGCAAGTGGAAGCGACGATGGGCAGTGAGCAAGCTCCCTCCCTGCTGCAGCGCATGCCAGTGGTGCTGACCCAACTGTCTCGACCCAATGGCTGCAAGCAAATTCAATGCATGATATGCCTATCGCAGCATACCAAAATCTCTGATCTGCGCACTCATTTGCTAAATCATCAGTATTCCGTCAAATTTACAGAGGAGCGGGGTCAGCCGGAGAGCATAGAAAGCATTTCACGTTCTCTATACCCAGAACTAGCCGCACctttggagcagcagcagctaatcGAACGCATTCAAAGTGATGTGACAAAACGCGTGGAGCTGGAAAGATTCATTTCCATTACCAACGAGGCGGGCATTGAGCTCAGCCTGGAGAGCAGCGAAACGGAAAGCGATTCGGACTCTGCCGAGGCCGACAGGAGCAACAGCGAACTACTCTACAACTGTGAGCTATGCCAGACGAAGGTTTCGCGAAAGCATCAGCTCTACGCCCATGAGCTGGAACATCATTCGTGGCAACAGGCAACGCGTGTTTGTAACTGCTGCCAGGCGAGATTCGTAAATGAGCAGCTACTAGAGCATCACTATCGGACGCTCTGTCGCAACGCGCACCGTCGATTCTTTTGTCGTAAATGTCCGCTACGTTTCCGCTGGCGCGAGAATCTGAAACTGCACTCGGACGTAGCGCACAACGAAGCCAAAGGTGAGCAATCGAGCCTGGACATCAAGTTAAACGGGGCGCCCTTGTTACCCACCGGAAGTTACGACTGCTCCGCATGCAATCGTAGCTTTAAAATGCAGAAGGATCTTACCAGGCACACTCTGATGCATGGCCAAGAGTCAAGCATTTATCGGTGTCGCTGGTGCGCACGACGTTTTTATCGTCTGGCCAATTTGCTGCAGCACATCGAGCGTCACGGCATTAGCGCCGAGCAGCTGCCCTATGCTGAGGCACTGCTGAATGCCAGTCGTCATCCGCATGGTCAAAAGGTGATCCAGTGCAAGGTGTGTAATCTGACCTACCCCACCATTGCTGCGCTCCGCATCCATCTTCAATCGGCGCCAGCGGGCACACATCATGAGTTTGGCTCGTTGCTAAACTACTCTATTACCAATCAGTTAGGATACGAGTTGCATCTGGAAGACTCTGAAACGGACGAGGACACGAAGCCGCCAGGCACGCCCGCGTACTACACTTGTGGCATCTGCCAACTGCGCTGCGTGCGCAAGTTCGagctgcatcagcatcagcaagcGATGCATCGACTGGAGCGTATAAGCGAGGGCTGTGATGCCTGCATCTTTAAGAGCGTCTCAGCAGATCTCATCGGCTATCACCGACGCGTCCTGTGCAATAATACGGAAAAGCGCTTCAAGTGCTCCAAGTGTGGCTACAGGTTTATGTGGGAAACGAATCTGTTGCAGCACATCCAATTGCAGCATCCAAGTAGCGAAAGTGGCGGAGCGCAGCCGGATGCAAGTTCTTTGTCGGCACAGAAAGGGCCCAGCGGAGAGtgtcaaatatttcaatgcgGCCAGTGCCCTAGTAAATATAATCGCAAGGATCGTCTCACTGCTCATGTAAAGAAATGCCACGTAGCGGAAGCCAGTGGTCCCACTTCTGCCGCAGCGAACCTTATGAAAACTTCAAGTGGCCCCAAGCAGCAGAAAAGTTTTCTCTGCGCTTTCTGCGGCAAGGCGGTTAGTTCGTCCTCCAATCTGATTATACACATACGTCGCCATACTGGCGAGAAGCCATTTAAGTGCGACTACTGCGACATGGCTTTTCCTCGATCCTCCGACCTGCAGTGCCATAGACGCACCCACACTGGCGAGCGGCCGCACATTTGCACCGTTTGCCAGAAGGGCTTTGCCCGATCGTACAAGCTGCAGCAACACATGCGCATCCACAATGGCGAACGACCGTACAAGTGTACCTATTGTGACAAGAGCTTTACGCAGTCGAACGACCTGACACTTCACATACGACGGCACACAGGCGAGCGCCCCTATCAGTGCAATACGTGCGGCGAACGTTTCATACAGGGCACAGCCCTGAAGAATCATCGCCTACAAAATGGACATCACGACACGGAAATAGACCAGGTCAAAGATAACTAA
- Protein Sequence
- MLPTDICRTCTLYDDSLLPLATHTDKYANKSLNDMLLELTQNDPLQEHSDDSLPQQLCIGCLHKLEAAYAFVVQARQAREQLLLQLRNSVQTQCLDEMPIDINLQHIKTETIVDLQLTSKTKNEEDDTEGEEREVTAVSIPVLKWQPDSDSESNRTAADDQEVDFKPKKLRRSSRKAKGGSDSEIASTSPHDNPLPNAKRRRGRPARLLNKETVNEEGRHVCEVCGKTFSWYRDMQRHSRVHFEQANFVCDSCGKSFLRKDKYMFHLRSHEKRAAKFQAMELGSEWRFAERLYSSGRLKRAECKLCGLKYQRIGELREHLASHKNIETLSKLSLESDVIREQFAKEQQHVDLALIKQKLCADIAKGRDQLDKYCAVVNAYGYELCLSDSDEEVAGRSPEYQCVACNINFSRKYRLMRHTLEEHTQADRTVSWQRCDICQIGFVCANMFEQHKRTQCHNKLKRYNCPHCPGKFIWVQNLEQHACSQRTKQHDEQRLQMQCCLCDVQLNSMLELRTHLLIHQDGRSGIHPEQQATFFRTYYPNGLDCSLSELSARIASDFKAEDYGRYFNARTGNGEELDFFASDSELSELDQLNSGSTLHTCSLCGETNTRLGQLLKHQQSRHSEAQGKLPYVCGDCDLSFVADSLLKLHRRRVCAKQNANYECQQCSLRFYWLSNYELHMRVQHDTQIALQADDADDQEGQSRMRSKHQSTGSKLQCGECEKVFVWPKDLTRHKRLHQPQALAQYQCLHCDRKFHRKDGLKSHMRVHGEQQVEATMGSEQAPSLLQRMPVVLTQLSRPNGCKQIQCMICLSQHTKISDLRTHLLNHQYSVKFTEERGQPESIESISRSLYPELAAPLEQQQLIERIQSDVTKRVELERFISITNEAGIELSLESSETESDSDSAEADRSNSELLYNCELCQTKVSRKHQLYAHELEHHSWQQATRVCNCCQARFVNEQLLEHHYRTLCRNAHRRFFCRKCPLRFRWRENLKLHSDVAHNEAKGEQSSLDIKLNGAPLLPTGSYDCSACNRSFKMQKDLTRHTLMHGQESSIYRCRWCARRFYRLANLLQHIERHGISAEQLPYAEALLNASRHPHGQKVIQCKVCNLTYPTIAALRIHLQSAPAGTHHEFGSLLNYSITNQLGYELHLEDSETDEDTKPPGTPAYYTCGICQLRCVRKFELHQHQQAMHRLERISEGCDACIFKSVSADLIGYHRRVLCNNTEKRFKCSKCGYRFMWETNLLQHIQLQHPSSESGGAQPDASSLSAQKGPSGECQIFQCGQCPSKYNRKDRLTAHVKKCHVAEASGPTSAAANLMKTSSGPKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHHDTEIDQVKDN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00509945;
- 90% Identity
- iTF_00586811;
- 80% Identity
- -