Drep010457.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila repleta
Gene Symbol
-
Assembly
GCA_018903745.1
Location
JAEIGN010000345.1:2480324-2490229[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.5e-05 0.00096 19.3 2.1 1 23 178 200 178 200 0.97
2 18 4.9e-06 0.00032 20.8 0.4 1 23 206 228 206 228 0.97
3 18 0.00072 0.047 14.0 0.9 1 23 234 256 234 256 0.95
4 18 1e-05 0.00067 19.8 3.1 1 23 262 284 262 284 0.97
5 18 2.4e-05 0.0015 18.6 4.7 1 23 290 312 290 312 0.99
6 18 4.3e-05 0.0028 17.8 5.7 1 23 318 340 318 340 0.97
7 18 2.1e-07 1.4e-05 25.1 4.3 1 23 346 368 346 368 0.98
8 18 7.6e-08 4.9e-06 26.5 2.4 1 23 374 396 374 396 0.97
9 18 4.4e-05 0.0028 17.8 6.7 1 23 403 425 403 425 0.97
10 18 7.7e-05 0.005 17.0 6.5 1 23 431 453 431 453 0.98
11 18 6.9e-06 0.00044 20.3 4.5 1 23 459 481 459 481 0.98
12 18 5e-06 0.00032 20.8 8.1 1 23 487 509 487 509 0.98
13 18 2.1e-06 0.00013 22.0 7.2 1 23 515 537 515 537 0.98
14 18 4.5e-07 2.9e-05 24.0 7.7 1 23 543 565 543 565 0.98
15 18 0.00014 0.0091 16.2 9.5 1 23 571 594 571 594 0.95
16 18 5e-05 0.0032 17.6 0.9 1 23 600 622 600 622 0.98
17 18 0.00055 0.035 14.3 3.4 1 23 632 654 632 654 0.97
18 18 6.3e-06 0.0004 20.5 1.6 1 23 660 683 660 683 0.96

Sequence Information

Coding Sequence
ATGCATCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGCCATTGCCCGGCAACAAGTCTGATCATAAAGAGGACGGCAGCAAGCCGCCGCACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAGTTATTTACATACCACGAGGTATTTGGCAAGATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGGAGTCAGTTGCCACCGCCGCAATTGCCCCCGCCGCCGCCATTACCGCCGCAGACGACGCATTCGGCTAGCGCAGCTGCAGCTGCAGCGGCGCAGGGCATCGCCACGGTGACCACAACTAGCTCCTCCGGCAGCAACGGGGGGAATGCGACAACGACGGTTAAGGGTGAGTTGCTAATGCCCAAAATGGAGGGCGGCATCCATGGCGTTGATGGACAATCGAGTGTTGCGTTGGCCCCAGATGGCACGCCCATTGCGACTGGGACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAATTTCGCTATCAGCTAATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTGTGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCAGGCATGGCAAGATCCATATTGGCGGTCCCATGTTCACTTGCATTGTCTGCTTCAATGTGTTTGCCAACAATACGAGTCTGGAGCGCCATATGAAACGGCATTCGACGGACAAGCCATTCGCGTGCACCATTTGCCAAAAGACTTTCGCACGCAAGGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCACATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCATGTGCGCCAGCATACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCATTTGACGAATCATGTCCGCCAGCACACGGGCGATTCGCCGCACAAGTGCGAATACTGCAAGAAGACGTTCACCCGCAAGGAGCATTTGACGAATCATGTGCGCCTGCACACTGGGGATTCGCCGCACAAGTGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAATCACATGCGCCAGCACTCCAGCGACAATCCCCACTGTTGCAATGTGTGCAACAAGCCCTTCACGCGCAAGGAGCACTTGATCAATCACATGTCACGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACGTGCGGCAAATCGTTCCCCCTCAAGGGCAACCTATTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGTGCGAGCGTCCATTCGCCTGCGAGAAGTGTCCCAAGAACTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAATGAAACCGATCATAACCCCCGATTAA
Protein Sequence
MHHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGNKSDHKEDGSKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAQGIATVTTTSSSGSNGGNATTTVKGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHKCEYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEMKPIITPD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00599004;
90% Identity
-
80% Identity
-