Basic Information

Insect: Drosophila repleta
Gene Symbol: ftz-f1
Assembly: GCA_018903745.1
Location: JAEIGN010000530.1:297400-334980[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 2 1.5e+04 -6.4 9.9 43 98 29 108 12 247 0.49

2 4 2 1.5e+04 -6.4 8.9 78 184 187 296 131 327 0.42

3 4 5.4e-20 4.2e-16 59.2 0.2 1 82 499 579 499 633 0.75

4 4 1.4e-72 1.1e-68 232.3 0.6 154 408 690 937 652 939 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	2	1.5e+04	-6.4	9.9	43	98	29	108	12	247	0.49
2	4	2	1.5e+04	-6.4	8.9	78	184	187	296	131	327	0.42
3	4	5.4e-20	4.2e-16	59.2	0.2	1	82	499	579	499	633	0.75
4	4	1.4e-72	1.1e-68	232.3	0.6	154	408	690	937	652	939	0.92

Sequence Information

Coding Sequence: ATGGAAAACTTTAGTGTACCTTTGCTGGCCGAGAGCAGCAACAATATCGTTAACTGTGCAGCCAGCGGAAACAACGATAGCCACAATCAACATCACCAGCAACTACAACAACCACAACAACACCACCATCAGCAACAATTGCTTCATAAAGATCATCATAAGGATCAATTGTTGGCAGCTGGGTGCAGTCCGATTTTACCCTTTATTAACTATGCCCAGTTGCATAAGGATACTCAGTCCAATTCTGATTCCAATCCGCCGGTTGACAGCTTTAGCTGCTTACAGGCCATCGACAGCAACCAATTGGATGTTGCTGTCTCTTTGAGCGGACTTTGCGATCGCATTTTTGCCAGTCCCAATCCGCATAGTAACAACAGTCCTGTTGATCCTAAAGTATCAGCGACTTCTATCGGTACCAATGGACCACTTATATTAGAATCAGCGACAATGTCATCTTTTGCCAATATACTGTTCAACAACCGCAATAACAATAACAGTACCCAGCCCACGGCTAACATCGGAACGCTCAACAGCATTGACCCACAGTTGCTCCAAAAGTCAAACTCTGCGGAGTACCATCAGCTAAAGCCATTAAAAAATAGAGTAGTCTCAACGCCGGTTGTGAGCACATCTGGATTTTTAAGCTCCACAACATCACATCTGTTAGACTTCGAAATGATACCGAGCAGTAATAATAAGGATTCTGTTATTGCAACTAGCAATGAAATGGCCGACACAACAACAGATGCACCACCGACATCAGAAAGTACAACCAATCGAAGATCGCTGCATAGCATAGACGAGCTGGCGGCCAGTTCTTGTACCGCGACTAAAGTCAACACTACAAACATTAATACCCAGGCGAAAAAACAAAATCAACAGCATAAACAGCAGGAAAATCAAGCCGGAAATCTGAGTGAATCCAATATTAGTTCCGACGATGAGTCTATCTCAGACGATGAATTCGGTCTAGAGATCGATGACCAAGGGGGCTATCAGGAAACAAATTCGTCCCATTCGCAGCAAAGCGGTAACGGCGCCGGCGTAACATCTGGTAACTCTGCCCAGCTACTAAACGGTGGCAGCAACAGCTCTGCCGGTAACGGTTATATGTTGCTGCCGCCAGGTGGCACTTCAGTTGCTCACATGTCCGTCAATACGGGTGGCACCGCAGCAGCAGGTGGAGCTGGCAATGTCGCCTCAACTGGCGGTGGTAATCATGGTGGAACCAGCGCCACCTCTGGTGGAGGCGAAGCCATCGACTTCAAGCACTTGTTCGAAGAGCTGTGCCCGGTCTGTGGCGATAAGGTGAGCGGCTATCACTATGGCCTGCTCACCTGTGAGTCCTGCAAGGGCTTCTTCAAACGGACTGTTCAAAATAAAAAGGTCTACACATGCGTCGCGGAACGCTCCTGCCACATTGATAAAACGCAGCGCAAACGGTGTCCATACTGCCGATTCCAAAAGTGCCTTGAAGTGGGCATGAAACTCGAGGCGGTTCGAGCAGATCGTATGCGCGGCGGCCGTAACAAATTTGGACCCATGTACAAAAGGGATCGAGCACGTAAGCTGCAGGTGATGCGCCAACGACAGCTTGCTCTGCAAGCGCTTAGGAGTTCTATAGGCTCAGATATGAAGCCCTCGCCGCTCTCGCCTGGCTATCAGCAAGCATATCCAAATATGAACATTAAGCAAGAAATTCAAATACCTCAGGTATCCTCACTCACGCAATCGCCGGATTCATCACCCAGTCCCATTGCTATTGCTTTGGGCCAAGTGAATGCTAGCGCAGGCGGTGCGATAACCACGCCTCTGAATGTTGGCAATCTGAGTGGCGGTAGCTCACTAGGCAACAACAACGTCAACACCAACAGCGCTGGAAGCGGCGCAGGAGGTAGTGCGGGTGGCAATAACGCCGGCAGCGGAAGCGGTGCCAACAACAGCAACAACATCGCTGATGGCCTGCAACGTAACGGAAATAGCGGCAATAGCAACAGCAGCTGTCATGAAACTGGGAATGGATCTCTACAAAACACAGCTGAATCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCAGACGCAGTCATTGAGCCACTGAGGGTCTCTCCGATGATACGCGAGTTTGTGCAATCAATCGATGATCGGGAATGGCAAACTCAGCTCTTTGCGCTGCTGCAAAAGCAGACGTATAACCAAGTTGAAGTTGATCTCTTTGAGTTAATGTGCAAAGTGTTGGATCAAAATCTCTTCTCACAAGTGGATTGGGCAAGAAACACAGTCTTTTTTAAGGATTTGAAGGTGGATGATCAAATGAAGCTGCTTCAGCATTCTTGGTCGGATATGCTTGTGCTGGATCATCTGCATCATCGCATACATAACGGTTTGCCCGATGAAACGCAGCTTAATAACGGACAGGTGTTTAACTTAATGAGCCTTGGCTTATTGGGAGTTCCACAATTGGGTGACTACTTTAATGAGTTGCAAAATAAGCTGCAGGATCTTAAGTTCGATATGGGAGACTATGTGTGCATGAAATTCCTGATACTTTTAAATCCAGATGTACGCGGAATAGTGAACAAAAAGACCGTTGTGGAGGGACATGAGAATGTTCAGGCAGCGCTTCTGGATTACACACTTACGTGTTACCCCTCAGTAAATGACAAATTTAGGAGGCTTTTGAATATACTACCGGAAATTCACGCCATGGCCGCGCGCGGCGAAGAACATCTATACTCAAAACATTGTGCAGGTAGTGCACCCACGCAGACACTGCTCATGGAGATGCTGCATGCTAAACGAAAGGTGTGA
Protein Sequence: MENFSVPLLAESSNNIVNCAASGNNDSHNQHHQQLQQPQQHHHQQQLLHKDHHKDQLLAAGCSPILPFINYAQLHKDTQSNSDSNPPVDSFSCLQAIDSNQLDVAVSLSGLCDRIFASPNPHSNNSPVDPKVSATSIGTNGPLILESATMSSFANILFNNRNNNNSTQPTANIGTLNSIDPQLLQKSNSAEYHQLKPLKNRVVSTPVVSTSGFLSSTTSHLLDFEMIPSSNNKDSVIATSNEMADTTTDAPPTSESTTNRRSLHSIDELAASSCTATKVNTTNINTQAKKQNQQHKQQENQAGNLSESNISSDDESISDDEFGLEIDDQGGYQETNSSHSQQSGNGAGVTSGNSAQLLNGGSNSSAGNGYMLLPPGGTSVAHMSVNTGGTAAAGGAGNVASTGGGNHGGTSATSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGSDMKPSPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASAGGAITTPLNVGNLSGGSSLGNNNVNTNSAGSGAGGSAGGNNAGSGSGANNSNNIADGLQRNGNSGNSNSSCHETGNGSLQNTAESKLCFDSGTHPSSTADAVIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479510;
90% Identity: iTF_00586729;
80% Identity: iTF_00586729;