Basic Information

Insect: Drosophila rellima
Gene Symbol: zfh1
Assembly: GCA_035043635.1
Location: JAWNMV010000811.1:3731531-3757928[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0058 0.41 11.3 1.8 2 23 76 98 75 98 0.95

2 9 0.00093 0.065 13.8 0.1 1 23 275 297 275 297 0.97

3 9 8.7e-05 0.006 17.0 2.0 3 23 312 332 310 332 0.97

4 9 8.2e-05 0.0057 17.1 4.9 1 23 341 363 341 363 0.98

5 9 0.00023 0.016 15.7 1.4 3 21 371 389 369 390 0.94

6 9 0.0075 0.53 10.9 0.7 2 21 637 656 636 657 0.92

7 9 1.5e-05 0.001 19.4 0.5 1 23 1015 1037 1015 1037 0.94

8 9 5.4e-05 0.0038 17.6 7.4 1 23 1043 1065 1043 1065 0.98

9 9 0.0027 0.19 12.3 4.3 1 21 1071 1091 1071 1092 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0058	0.41	11.3	1.8	2	23	76	98	75	98	0.95
2	9	0.00093	0.065	13.8	0.1	1	23	275	297	275	297	0.97
3	9	8.7e-05	0.006	17.0	2.0	3	23	312	332	310	332	0.97
4	9	8.2e-05	0.0057	17.1	4.9	1	23	341	363	341	363	0.98
5	9	0.00023	0.016	15.7	1.4	3	21	371	389	369	390	0.94
6	9	0.0075	0.53	10.9	0.7	2	21	637	656	636	657	0.92
7	9	1.5e-05	0.001	19.4	0.5	1	23	1015	1037	1015	1037	0.94
8	9	5.4e-05	0.0038	17.6	7.4	1	23	1043	1065	1043	1065	0.98
9	9	0.0027	0.19	12.3	4.3	1	21	1071	1091	1071	1092	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCGACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTACTCCATGCAGTTTCCCTCTTTGGCCTCCAGTTTGCACCACCATCCAGCACACAGCAAGCCCAGCAATGTGGCTGCAAATGAGGAGCTTGCCACACATGCGGCAAGTGCCGCAGCGAATGCGGCAGATGACTATTTGGTCAAATGCACGCAGTGTCACAAGCGCTTCAATGAGTTTCAGTCCCTCAGCGAGCATATTGCCAGCGAACATCCGCACGACAAGCTCAATTATGAGCCACATCGCGCCGCTGTCGCTGTGCAGCCGGAAAGCGACGCCGAGGAAGATGAGCAGAGCAATTTGAGCAGCAACAGTCGACGCTATGCCAAATCCccatccaacaacaacaacaatgagacaGCCAAGaatcaaaacaataacaacaacaatcacagcaGCCAACACTCGCCCATGTGCTCACCTGTTGGCCAAGCGCCGCCCGCTGATCTTTTCGCCCACCTGCCGCATCCGCCGCCGCAGCTGCCCGCCCACTTGCACGCCCAGTTCATGGCCGCCGCCGCATTGGCCATGCAGTCCGCTCGCTCCGCCAGCTCGCCCAgccaacagctgcaacagtcgccgcagcagctgcaacaccagcagccacaacagttgctgctgccaccgccTCAGcccggcagcaacagcagcgttGGCAGCAACTCCGCCTATGATCTGGATCTGAGTGCTCCACGCTCCACCTCCAGTCCGGGCTCCACAGCCGGCGAGCTGAGTGTCCCCTTTCCCTGCATGCAATGCACGGCGGCATTTGCCACTCGCGAGCAACTCGAGCAGCATCAATTGCTGCACTCGCCCACGGGACAGCAGACGTCGCAGTCTGTGCCACAGATTTGCAAAAAATGCCACAAGGCATTTGCCAATGTCTATCGCCTGCAGCGTCACATGATCAGTCACGATGAGTCGACGGCGTTGCGCAAATTCAAGTGCGCACTGTGCGAGAAGGCGTTCAAGTTTAAGCACCATCTGAAGGAGCACGTGCGCATCCATTCGGGCGAGAAGCCCTTTGGGTGCGACAAGTGCGGCAAGAGATTCTCGCACTCGGGCAGCTTCTCCTCCCACATGACGTCCAAGAAGTGCATCAGCATGGGCCTCAAACagaccagcagcaacaacaacaaccatggTAACAATCGACAAATGCTCAAAGCCTTGGATAAGAATGTCAGCGCTGGACGCTCGCCAACggatcaacagcagcaaatgagTGGAAAGCGTGTCTCCAAGCTGCCAGAATCGAGTCCCCTGCTGCCCAATCCCATGAACTACTTTGCTGGAGAGGCTCAGGTGCCGTCGGCAGCTGCGAATCCCGCTGCTCCCTTTTATTCCAGCTACAGCGCCATGAATGCGGCTCTGTTGGCATTTCCCAATGCGCTTATGGCAGCGGCGTTTGATCCGCGCCTGCCCACCTTTAGCATACAGCGCTTGCTGGAGCTGACAGCCGccggacaacagcagcagcagcaccaacaacaacaacaggaggagcagcaacatcagttggagcaacaacagcatctagagcaacaacagcaattggagGCGCCACTTTATGAGCCCAGcaaagatgaagatgaaaCGCCCGATGAGCCAAAGCTGGTCATGGATCTGGAGGAGTCGGAGACCAAGCCAGCCACGCCAGAGTTGCCGCCAGTTGTTGAAGCTAATCCCGATGCCGTCTCGCTCAAGCAGGAGCAGATTCGGGAGCCAACGCCTGCGCCGGAAGCGGCAGCAGATTCACCCAAGCCCATTAAGATGGAACTAGATCAGGAgcatgaggaggaggagctggtGACGGCACAGGATTTGCGCTGCAGTCGCTGCTCCAAGCAGTTCAATCATCCCACAGAGCTGGTGCAGCATGAGAAGGTGCTCTGTGGACTCATCAAAGAGGAGCTAGAGCAGCactaccagcagcagcaacaacaacaacagcagcaacaacatcaacaacagcaacaacatcagcaacaacaacaacactcttCCTTTGTAAGCGATgctgatgaagatgaagaggaggaggaaccACGACAGGATTACAACGCTggcggcagcagcgacagcggggAGCGCAAAGTCCGCGTCCGCACGGCCATCaacgaggagcagcagcagcagctgaagcagCATTATGCCCACAATGCGCGTCCATCCCGCGATGAGTTCCGTCTGATTGCCGCCCGTCTCCAGCTGGACGCACGTGTCGTCCAGGTCTGGTTTCAGAACAATCGCTCGCGGGAGCGCAAAATGCAGAGCTATGTGAGCAGCAACGAGGCACCAAGTGTccaggcaacggcaacgccACCACAACTCGCCCGAGCTGGCGAGGATCAGCCGCTGGATTTGTCCGTGAAACGGGATGCATCGCCGCTTTATGGCCTGGCGCCACAGCAGACGACGTTGAGTCAGCCGCCCGTGGATTTTGCCGACAACATGGCCATTAATCTGAGCCGCAAATTGTCCAGCTCGGCATCGATGTCGCCGGCTTCGCTGTCGCCCTGCTCCGGTGCCTCCtcgttgcaacaacaaacggcTGCGGCAGCGGCTGCAGCAGCGCTCTACTTTGCCCCGCCCTCGCCGCCCAGCATGCACGAGGCAGTGCCGCCAATGACGCAACAACGCGCCGCAGGGCCACATGCTCAACCCTTTCCCGGACTGCCGCCCTACATGATGCCACGCCTGCCCATGGAGGCGCTCTACCAGATGCGTCCCGGTGGCGACTATGCGCCCAATCTACTAATGAACAGTATTAAGCTGCCCGACTATCGTGGCACCAGCCTCAGTCCCGGTGGCTCCGAGAAGCGTTCCTGGCGCGACGACGACTCGCGCATCTCCCACGAGGATGACTATGTGATGGCCGGAGCGGGCGGACTGTTGCCACCGAAGCCCAAGCGCGCCAAGGCCGAGACCCATGGACATGCGGGCGATCCCGACCTGCCCTTCGTCTGCGATCAGTGCGACAAGGCGTTCGCCAAGCAGAGTTCCCTGGCACGCCACAAATACGAGCATTCCGGTCAGCGACCTTATCAATGCATGGACTGCCCCAAGGCCTTCAAGCACAAGCATCATTTGACGGAGCACAAGCGTTTGCATTCCGGCGAGAAGCCATTTCAGTGCTCCAAGTGCTTGAAGCGCTTCTCGCACTCGGGCAGCTACAGCCAGCACATGAACCATCGGTACTCCTATTGCAAGCCTTATAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIQQSMPSSTAYSMQFPSLASSLHHHPAHSKPSNVAANEELATHAASAAANAADDYLVKCTQCHKRFNEFQSLSEHIASEHPHDKLNYEPHRAAVAVQPESDAEEDEQSNLSSNSRRYAKSPSNNNNNETAKNQNNNNNNHSSQHSPMCSPVGQAPPADLFAHLPHPPPQLPAHLHAQFMAAAALAMQSARSASSPSQQLQQSPQQLQHQQPQQLLLPPPQPGSNSSVGSNSAYDLDLSAPRSTSSPGSTAGELSVPFPCMQCTAAFATREQLEQHQLLHSPTGQQTSQSVPQICKKCHKAFANVYRLQRHMISHDESTALRKFKCALCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCISMGLKQTSSNNNNHGNNRQMLKALDKNVSAGRSPTDQQQQMSGKRVSKLPESSPLLPNPMNYFAGEAQVPSAAANPAAPFYSSYSAMNAALLAFPNALMAAAFDPRLPTFSIQRLLELTAAGQQQQQHQQQQQEEQQHQLEQQQHLEQQQQLEAPLYEPSKDEDETPDEPKLVMDLEESETKPATPELPPVVEANPDAVSLKQEQIREPTPAPEAAADSPKPIKMELDQEHEEEELVTAQDLRCSRCSKQFNHPTELVQHEKVLCGLIKEELEQHYQQQQQQQQQQQHQQQQQHQQQQQHSSFVSDADEDEEEEEPRQDYNAGGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAARLQLDARVVQVWFQNNRSRERKMQSYVSSNEAPSVQATATPPQLARAGEDQPLDLSVKRDASPLYGLAPQQTTLSQPPVDFADNMAINLSRKLSSSASMSPASLSPCSGASSLQQQTAAAAAAAALYFAPPSPPSMHEAVPPMTQQRAAGPHAQPFPGLPPYMMPRLPMEALYQMRPGGDYAPNLLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVMAGAGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537703;
90% Identity: iTF_00585867;
80% Identity: iTF_00585867;