Basic Information

Insect: Drosophila rellima
Gene Symbol: egg
Assembly: GCA_035043635.1
Location: JAWNMV010000145.1:4270197-4274834[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.1e-14 1.3e-10 40.8 0.0 5 75 960 1023 957 1025 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.1e-14	1.3e-10	40.8	0.0	5	75	960	1023	957	1025	0.90

Sequence Information

Coding Sequence: atGGCTTCGGATTCTGCAGCAATGGATTGCTCAGAACACGTAGATACGACGTCGACTGACACTTCAACAGAATtagttgcaaataaattgctcGTCGCGGCATCTTGTGACACCGGCATCGCAGAGCTTGCAGAAGAGAATATAACCTCTGAGGCTGAAGTCGATAAGCCAATGTCCTTAGACGAAGATGAGTCGTCAACTGTTGGCGATGTACCAAACGTCGAACCGTCTTCAAGTGAGCAAATTAAAGAGTCGGAAAGTGACAAGAGCGTCGAAAAAACAGCATCTGCTGATGagaaagataaacaaaatattaacaaaggCACTTCTATAACAAGTTCTAGGGAAGACATTGGATCTTCAATAGAAAAACTTGATTCAACTAAACCAATCGAGGCGGATTTGGATAGTAGCATTGAACTTATCAGTAGCCCGATTACTGACGATGTTGACGATATGGAAAAAGACACGGACTTCAATGAAGAAATTCGTGCACCATTTTTGAATGAAGGCACAAAATCTTCAATGGGAGATGTTGGATCCAGTAAACCAATTGAAGTTGATTTGGATAGCAGCATTGAAATGATTGAAAGCCCCGTAGCTGCACCTATATCTTCGGGCAACGTTGATCTGGAAGAATCAGTTGCAAAGGAAAAGGAACGCGTGGTCGACAGCGATAGCAGTATTGAACTCATTAGTAGTCCTGACAAAGACGCTGAAGGCGATAGGAATAAGGATTCATTTACAGAAAATATGGAGTCCAAGTTAGAGCCAGAAACAGAGTTGAAGCACACACACGATAGAGCAGAAGTGGTGCAGGAGCTAAAGACAGATCAAAAAGATGATATCCTGGTATCTACAGACAAGGATACTTTTGATGCCACAACAAATTACGATTCCGATGGCACCAAGGAAGAAACATTTAAGAACAAAGTGGAGGAATGTACCCTAGTTTCTCCACAATCCACACCGGACACACAGCTAGATGATAAAATTTCTGTACCACAGGAGTCTGCACACAAAACTGAGCACATGGAAATAGATGCAACCATCGATGATGCTATCGAGgaagaaaaactgaaaattgaagATATACTAGCAACAAAAGACGTCAAggaagaaaaactaaaaactgaagATATGCCAGAAACGAAGGACGTCGACATGATTGAAGGAGACGATTTGATTGAAGATCATGAAATCTACTATAAAAAGGATTGCGTTAACTGCAACTGCCAGAAGACGCACAAGCAATTTGTTCGCGCTAGCTTGGCAGTTCTTAACTATTTCAAAGTGCCCAGAAAGACACACAAGAGACAGTACATCTGCATGGAGTGCTATGACGCAGCAATGGATGTTTACGAGGACTATGCTGGTTACTTGTTCGCCAAGCagccgttgctgctgcgcgATTTTAAGCAAGACCATGCCGATTTTGTGGCACTGGACAGCAGCGATGAAGAGGAAAATGACGATGAGCCGAACAAAGCTGAATTTTCGCAAAATGACTTAAATCTAATTGAAGGCGAGTTGGAGGATGCTATCAAAACTGTTATGAGTAAGGTGAATATGAGCGACCAAATGGCTTGGTCGAAAACCATCTTGCAATCAAAGTCGGACCGCATAGGACTTGAACTCGATTTGGCCAACGATGAGCTGAGTAAGCTGCAAAATATGGCCGATAAAATGCACTTTGCTTTGTACAACCACTGTCAAGTGGTGCATAAGCATTTGCCGCCACTAGATCTCTACCAAAACATGACTGATTATGTGCAAGTCCCGCCAGCTGGAGATATAGAGCGTCCGCCTATTCAACTCAACGAGACCTATTATGCTGTTAAGAATAAGGCCATTGCCAGCTGGGTATCAGTCAAAGTGATTGAGTTCACAGAAAGCACAACTGTTGGCGGTCACTTAGTTAAGAGCTACAAAATCAGGTATCTCAATACGCCATACCAAATGGTCAAAACTGTAACGGCCAAGCATTTAGCCTTCTTTGAGCCGCCACCAGTCCGCCTAACAATTGGTACTCGGGTAATAGCCTATTTCAATGGAAGCACGCTGTCGCGCGGCAAGGAGCGAGCCGTAGTACCCAGCGCCTTCTATCCGGGAATTATTGCAGAGCCCTTGAAGCAGGCCAATCGATTCAGATATTTGATCTTCTATGATGACGGTTATACGCAGTACGTGCAGCACAATGATGTGCGTTTGGTTTGCATGGCATCGGAGCGAGTGTGGGAGGACGTGCACCCCGGCTCACGGGATTTCATTCAAAAGTATGTGGAGAAATACTCCGTTGACCGACCGATGGTGCAATGCACGCGTGGCCAAAACATGAACACCGAATCAAACGGCACCTGGCTCTATGCCCGCGTCATTGACATCGATTGCAGTCTTGTGCAAATGCAGTTCGACGATGACAAGAATCATACAGAGTGGATATATCGCGGATCCTTGCGACTGGGACCCGTCTTCaaagaaacacaaaatgcGCTTAACAGCGCCAATGCCATGCAACAGCATCGTTTGCCGCGTCGCACTGAGCCGTTTATACGCTACACCAAGGAAATGGAGACAAGCAATAGACAGGTTAACCAGCAGATGCGAGCCATTGCGCGGAAGAGCAGCTCTGCTCCAcaaaatgtcaacaatttACCGACATcttcagcagcagcggcagctgtcAATGCTACAACTGCAGTACGCAACACGGTGCGACATTTGAACAACTCGACGATCTATGTAGATGACGAGAATCGACCCAAGGGCAATGTAATCTACTTCACTGCCAAGCGGAATGTCCCACCTAAGATGTACACGCCCCATGGATGCTCACCGGGTTGTTTGTTCAAGATTGTACATCGTTTGGACAGCTACAGCCCGTTGGCCAAACCACTGCTCTCTGGTTGGGAGCGCTTGGTTTTTAAGCAGAAGGCTAAGCGTAACGTCGTCTATCGAGGACCTTGTGGCAAGAGTTTCCGCAATCTGGCCGAGGTCCACGCTTATTTAAGAGTCACGGAAAACGTGCTGAATGTGGAAAACTTTGACTTTACGCCAGATTTGCGTTGCCTAGCCGAATATTCCATTGAATCTCCCATTGTGAAGGATCCGGATATTTCCAAAGGTCAAGAGAAAATGCCTGTTCCACTGGTTAACTACTATGACAACACCTTTCCACCGCCCTGTATCTACGCCAAGCAGCGCATACCCACAGAGGGCGTGCATTTGAATCTCGACGAGGAGTTCCTGGTGGGCTGTGATTGTGATGATGATTGCTCGGATAAATCAAAGTGCGCCTGCTGGCAGCTGACGGTTGCGGGCGCCAAATACTGCAATCCCAACAAACCCATCGAGGAGATTGGATATCAGTATAAGCGGCTACACGAGCATGTTCCCACGGGCATCTATGAATGCAATTCCCGCTGCAAGTGCAAGAAGAACTGCTTGAATCGTGTGGTGCAGCACTCGCTTGAAATGAAGCTGCAAGTTTTTAAGACTTCGAATCGTGGCTGGGGATTGCGGTGCGTTAATGATATACCCAAAGGTGCcttcatatgcatatatgcagGTCACTTGCTCACCGAAACTATGGCCAACGAGGGCGGTCTGGATGCTGGTGATGAATACTTTGCCGACTTGGATTACATTGAGGTGGCCGAGCAACTGAAGGAGGGCTACGAATCGGACGTTGAACACTCGGCAacggaagaggaagaagataCTTATGCTCCAGATCCAGACGACGATGATGAATTCAAACCCAATAAGTATTACCAGCCTCGCAAAAAGGACAAGTTGCGGGCTTCTCGCAGCCAATCGAATCAGGCTAATGAGTTGGATTCGCAAGAGCGTGcagtaattaatttcaatccAAATGCTGACCTGGATGAAACAGTGCGTGAAAATTCAGTACGACGGCTCTTTGGCAAAGACGAGGCTCCCTACATAATGGATGCAAAGACAACCGGCAATTTGGGTCGTTACTTTAATCACTCTTGTGCACCCAACTTGTTCGTGCAAAACGTGTTCGTGGACACACATGATCTGCGTTTTCCATGGGTTGCTTTTTTTTCGGCCGTTCACATTCGTTCTGGCACTGAGCTAACTTGGAATTACAACTACGAAGTCGGTGTGGTGCCTGGAAAAGTTCTGTATTGTCAATGCGGAGCTTCGAATTGTCGCATACGTTTACtttaa
Protein Sequence: MASDSAAMDCSEHVDTTSTDTSTELVANKLLVAASCDTGIAELAEENITSEAEVDKPMSLDEDESSTVGDVPNVEPSSSEQIKESESDKSVEKTASADEKDKQNINKGTSITSSREDIGSSIEKLDSTKPIEADLDSSIELISSPITDDVDDMEKDTDFNEEIRAPFLNEGTKSSMGDVGSSKPIEVDLDSSIEMIESPVAAPISSGNVDLEESVAKEKERVVDSDSSIELISSPDKDAEGDRNKDSFTENMESKLEPETELKHTHDRAEVVQELKTDQKDDILVSTDKDTFDATTNYDSDGTKEETFKNKVEECTLVSPQSTPDTQLDDKISVPQESAHKTEHMEIDATIDDAIEEEKLKIEDILATKDVKEEKLKTEDMPETKDVDMIEGDDLIEDHEIYYKKDCVNCNCQKTHKQFVRASLAVLNYFKVPRKTHKRQYICMECYDAAMDVYEDYAGYLFAKQPLLLRDFKQDHADFVALDSSDEEENDDEPNKAEFSQNDLNLIEGELEDAIKTVMSKVNMSDQMAWSKTILQSKSDRIGLELDLANDELSKLQNMADKMHFALYNHCQVVHKHLPPLDLYQNMTDYVQVPPAGDIERPPIQLNETYYAVKNKAIASWVSVKVIEFTESTTVGGHLVKSYKIRYLNTPYQMVKTVTAKHLAFFEPPPVRLTIGTRVIAYFNGSTLSRGKERAVVPSAFYPGIIAEPLKQANRFRYLIFYDDGYTQYVQHNDVRLVCMASERVWEDVHPGSRDFIQKYVEKYSVDRPMVQCTRGQNMNTESNGTWLYARVIDIDCSLVQMQFDDDKNHTEWIYRGSLRLGPVFKETQNALNSANAMQQHRLPRRTEPFIRYTKEMETSNRQVNQQMRAIARKSSSAPQNVNNLPTSSAAAAAVNATTAVRNTVRHLNNSTIYVDDENRPKGNVIYFTAKRNVPPKMYTPHGCSPGCLFKIVHRLDSYSPLAKPLLSGWERLVFKQKAKRNVVYRGPCGKSFRNLAEVHAYLRVTENVLNVENFDFTPDLRCLAEYSIESPIVKDPDISKGQEKMPVPLVNYYDNTFPPPCIYAKQRIPTEGVHLNLDEEFLVGCDCDDDCSDKSKCACWQLTVAGAKYCNPNKPIEEIGYQYKRLHEHVPTGIYECNSRCKCKKNCLNRVVQHSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGLDAGDEYFADLDYIEVAEQLKEGYESDVEHSATEEEEDTYAPDPDDDDEFKPNKYYQPRKKDKLRASRSQSNQANELDSQERAVINFNPNADLDETVRENSVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCAPNLFVQNVFVDTHDLRFPWVAFFSAVHIRSGTELTWNYNYEVGVVPGKVLYCQCGASNCRIRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00528801; iTF_00537508; iTF_00533798; iTF_00585194; iTF_00510539; iTF_00522955; iTF_00506862; iTF_00575580; iTF_00519159; iTF_00601789;
90% Identity: iTF_00601789;
80% Identity: -