Basic Information

Insect: Drosophila rellima
Gene Symbol: -
Assembly: GCA_035043635.1
Location: JAWNMV010000302.1:2209885-2214532[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.1e-15 9.6e-12 44.4 0.0 5 73 440 504 437 507 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.1e-15	9.6e-12	44.4	0.0	5	73	440	504	437	507	0.87

Sequence Information

Coding Sequence: ATGAGTTTCCCGAATCAACCCGTTGACACGGGGGGCAGTAATGGCCCGAAGCGGCAATCCTTTCCCCCGAGCAGTTCTAGCAATGATTCTGATCGAGGCAACAATGGCTATAGCCTTAATTTAAATGGAGAATTGGATAAATCGGATGTTTCGCAGCCATTGCCGGCGGAACGGCAGAATGCCGTTGAGAATGGTGGCACTTCTGGCAGTCGCAAGGCCAAGAAGCATAAGAGCAAAAGGTCAAAGAAACGCCGCGATTCAAAGGAAGTCGCACTTGTTGGTTGGAATGGCGTTTTTCCCAATCTATCGTCGACTCACAGCCTGGAGAGCAACTCGGATGTAGATCTTTCGCAGCTGCCGGCTGATCTAAGGGCCATAGGTGCCACCGGCCTAAGCGTCTTCCCCAGGCAGagggaggagcagcagcagcaacagccgcagTCAAAGTCGCCAATGTTGTCctcgtcgccgtcgacgtcttcttcttcaacGTCTACTTGCTCTCCAACTGTTTTACATGATAAAACATCtgcgacaagaacaacagcaacggcagcagcaacaacaaccacgacaccaacaacacctACAACAActtcgacaacaacaaccacttgTACAATTACTACAAATTCGACTGCTTCTAGTCCAACGTCGACGCCGACAGcaaccaacaaccacaacaacaacgacgagaacaacatgaacaacgacaacaacagttcAACTTCAATTGTTTGTCCAACTTTCGAGGCATCATCagaaccacaaccacaaccacaaccagaACATGAACCTGAACCTGAACCAGAATCTGAATCAGAAACAGTAACTGATTTATCTAAGCAGAACGACAAGAGTCGCAAGCAACATCGCTATCAGCCAGGTGACGATATTCCGACTCCACCTCGTCTCAGTCCCTGTTCTCCGCCTCCACAGGAAATCTCGAACGGATCCTTTGCGGCCTCCCGCAAGCGTCCGCCCACCTCACAGGCTGATTCAGCCATCGAGCCACCGGAAATCGATGCGAAACGTGTGAAGCACTGGCCACCGACAACAGTGGAGGCATCCACAGTTGGTCGTAGTAATCTTCGCACACGCTCCAAGTCGTTGTATCAAGCAAATCCGGAGCTTGTTACTCGCTTAACACGTGCACGCAGCATTTGTGGAATCGCTGCCAcctcgacgtcgtcgtcgtcgacgctTAAGGAGCCCGAGGCTGTCGATTTGGCGCCACTGAATGACCGACGTCGATCTGGGACTGGGGctggagctgcagctggaactggaactggtgGCAAGCTGCCGGCCACCGATAAATACTATTGTTTGCCCTTCAAGTACGGCTGGAAGCGTGAACTTGTGCTGCGCAGCAATTCCTCGCTGTCGCGTCAGCGTGGCGACGTCATATTCATATCGCCGGCGGGCAAAAAACTGCGCTCCCGCGATGATATTATTCCACTGCTAACGGGCGAATTGACCATTGATCACTTCTGCTTCCAAAGGCAGATGCAGCAGGCGGGCGATGAGTTCGAGTCGGTGCGCCAAGCGCAGCCGGCAACGTTGCGTCGCCAATCGTTGGCCGCTGccaagcagctgcagcagcagcagcaacaacaacaacaacaacagccaagtctgcaacaacaacaacataagcgCACACCCGGTTCCGGCAAACGTGTGCCCAAGCCCAAGGTGCCCAAAGGCGCCAGTCCGCCGCCAGAGGGTTGGACCTCGACAATGGCCGTCAAGGGCAATGCTCGCGTTTTGGCCGCCAGCAATGGCAACTCCAGTGCCGCAACTGGTTCCAGTGCCAGTGGCCACAATGCACGCAAACGCAGCCATCAGTCGAAGCAGTCACCAAAGATCCAGGGAGCTGTGACAGTGCCAGCTGCTCCATTGCAGGTCAAGACTCAACCGCAATCACAACCACAAGTTCCGAGTCTAGTTGAGCAACCGCTGTCGCCTCAGTTGGGGGACAACAAGATGATCTGCGTCTACTGCCTGCAGCCGATCAAGGAGCGACAAAAGGCGTATCCGGTTGGCATGGACAATGTCAAGAATTACATTTGTTCGTCGTGTATTAAACCCACACAGAAATCCTTTGTGCCACCCAAGACACCACAAACGGCAGCTGAAGCGAATGGCGTCAATAAGCAGGATAAGGAACTAATCGATGAGAATGTGAATGCCAAtgtcaatgccaatgccaatgccaatgccaatgccaattccAATGCCAATGCGAATGCTGGCAACAAATTTGGCTACAAGGAGGCTGTCTTTGAGCAAAATGGCGATAGCAATGGCAGCATGCTGGGAATTGCCGAGGAGATTGAATTGCCCGGTGCTCTGCCGCCGGATCAGCTACTTAGCGATGATTCGCCCATCAGTCGTGCGGGTAACAAGATCACGCCCAAGCCCCAGGAAATTGTTGTCATTAACGGTCGCAAGGCTCTCGCCATCGCAGGCGAACCGCCGCGTCGTCGTTTACAAGTCATTCCTCGCGAACCGAACTTGGAGCTCTACGAGAAGCACTATCATCCGAAGCGCAATTCCAGTGTCAAGGAGAAGCGTCAGGGTTTCATTGAATGCATGTCCGCTGGCAATCTCAGCTGCCAGGTGATGACGGCCGTAATGAAGACACTGGATCTGCATGATCGAGTCCGCATGTCGAGCGTGTGCAAGACTTGGGCAATGATCGGACGTGATCGCAGTGTTTGGCGTACGGTGAAGCTGCGCAACACGCACATCAACAACTGGTTGTCCTGCATGCGTGACCTGGTGCGTTATCGCACCCGTGAGCTGGACATGATGGGCGTCAAGTGGGAGAATCCCAGGCTGCGCATGGAGGGCGATATGCGTGTGCTGAAATCGTTGCGCATTTTACGCACCGATGCCTGCGAGGCCGAGTTCATGCATTCGATCCTTAAGCGCCTGACGCGTCTCCTGGAGCTGCGTGCCACATGCACCAGTCGCGTCCTCAGCTTGGCCAACATCGAGAAGATGGTGGATCTGCGGGTGCTGCGCATTCGCATGACCGAGCCCAAGGCCAGCATTGTCTCGTTGCAGCCGCTGCAGAAGCTGGAGCACTTGAGGGAGCTCAGCCTGCGCGGCATCAACAACATGGCCCAGttggagctgctgcagctgcagggATTGAAACAATTGGAGACTCTGATACTGGGCTCCTGTCGCGGCATGAAGGTTGCCGCCTTCGGTGACCATGTGCTGCCCAGCCTGAAGAGACTGCGTCATCTGCGCCTCGAGAATCATCCCAGCAATCGGTCGTTCAACATCACTGAGATTATGAGGGGCATCGCCGTTGGAGGTGGCACCGTCAAGCATCTCGAGCTGAtcaatgtgaatgtgaatgccgAATTTAGTAGCCAACTGGCCAAGTGCAAGTCGGTTGAGGAGCTGCTCTTGATGCCCAATTTCCATAACAATACCGCCTACATAATGCACTACGTCATGCAGGCCATCAATGAGAATAGCGAACAGTTGAATGTATTCCGTTTGGGCATCACCTTCGAGCTGCTGAGCGTGACCCGTGCACTGGCCATGAATCGCGAAAAGGACTGCATCCCGGTGGCATTGCCCATTCCGGGTGTCCCCGAGAACGACATGTTGAACGAGTCGGATGAGCCAATTGCCTATTTGCCGGTCGACCGCCTCGAGTCCATACTGCACCACATGATGCCACAGGCTTGGCTGACCGTTGCCAAGGTATCGCAAAGCGAGACTACTAACTTGAAATTTCTTTTGGCCTCGACGCCGATGGATTCAGCCGCCAGTGCTCCCAATTCAATCTAA
Protein Sequence: MSFPNQPVDTGGSNGPKRQSFPPSSSSNDSDRGNNGYSLNLNGELDKSDVSQPLPAERQNAVENGGTSGSRKAKKHKSKRSKKRRDSKEVALVGWNGVFPNLSSTHSLESNSDVDLSQLPADLRAIGATGLSVFPRQREEQQQQQPQSKSPMLSSSPSTSSSSTSTCSPTVLHDKTSATRTTATAAATTTTTPTTPTTTSTTTTTCTITTNSTASSPTSTPTATNNHNNNDENNMNNDNNSSTSIVCPTFEASSEPQPQPQPEHEPEPEPESESETVTDLSKQNDKSRKQHRYQPGDDIPTPPRLSPCSPPPQEISNGSFAASRKRPPTSQADSAIEPPEIDAKRVKHWPPTTVEASTVGRSNLRTRSKSLYQANPELVTRLTRARSICGIAATSTSSSSTLKEPEAVDLAPLNDRRRSGTGAGAAAGTGTGGKLPATDKYYCLPFKYGWKRELVLRSNSSLSRQRGDVIFISPAGKKLRSRDDIIPLLTGELTIDHFCFQRQMQQAGDEFESVRQAQPATLRRQSLAAAKQLQQQQQQQQQQQPSLQQQQHKRTPGSGKRVPKPKVPKGASPPPEGWTSTMAVKGNARVLAASNGNSSAATGSSASGHNARKRSHQSKQSPKIQGAVTVPAAPLQVKTQPQSQPQVPSLVEQPLSPQLGDNKMICVYCLQPIKERQKAYPVGMDNVKNYICSSCIKPTQKSFVPPKTPQTAAEANGVNKQDKELIDENVNANVNANANANANANSNANANAGNKFGYKEAVFEQNGDSNGSMLGIAEEIELPGALPPDQLLSDDSPISRAGNKITPKPQEIVVINGRKALAIAGEPPRRRLQVIPREPNLELYEKHYHPKRNSSVKEKRQGFIECMSAGNLSCQVMTAVMKTLDLHDRVRMSSVCKTWAMIGRDRSVWRTVKLRNTHINNWLSCMRDLVRYRTRELDMMGVKWENPRLRMEGDMRVLKSLRILRTDACEAEFMHSILKRLTRLLELRATCTSRVLSLANIEKMVDLRVLRIRMTEPKASIVSLQPLQKLEHLRELSLRGINNMAQLELLQLQGLKQLETLILGSCRGMKVAAFGDHVLPSLKRLRHLRLENHPSNRSFNITEIMRGIAVGGGTVKHLELINVNVNAEFSSQLAKCKSVEELLLMPNFHNNTAYIMHYVMQAINENSEQLNVFRLGITFELLSVTRALAMNREKDCIPVALPIPGVPENDMLNESDEPIAYLPVDRLESILHHMMPQAWLTVAKVSQSETTNLKFLLASTPMDSAASAPNSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601788; iTF_00533797; iTF_00585193;
90% Identity: -
80% Identity: -