Basic Information

Insect: Drosophila quinaria
Gene Symbol: hang
Assembly: GCA_035047525.1
Location: JAWNPO010000455.1:18734470-18750988[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.4 32 5.6 1.0 3 23 501 522 500 522 0.93

2 18 0.5 40 5.3 3.2 3 22 629 648 627 648 0.89

3 18 0.00086 0.068 14.0 3.3 1 22 751 772 751 774 0.90

4 18 0.099 7.8 7.5 0.1 2 21 786 805 785 806 0.93

5 18 0.00099 0.079 13.8 0.2 2 23 938 960 937 960 0.95

6 18 0.0029 0.23 12.4 0.1 1 23 968 991 968 991 0.96

7 18 2.3e-05 0.0018 18.9 0.1 2 23 1077 1098 1076 1098 0.97

8 18 0.00041 0.033 15.0 2.9 2 23 1214 1236 1213 1236 0.97

9 18 0.032 2.6 9.1 0.2 2 23 1245 1267 1244 1267 0.95

10 18 0.0031 0.25 12.3 0.1 1 23 1280 1303 1280 1303 0.97

11 18 0.00018 0.014 16.2 1.1 1 23 1345 1367 1345 1367 0.99

12 18 0.0028 0.22 12.4 0.9 1 23 1375 1398 1375 1398 0.96

13 18 0.097 7.7 7.5 0.4 2 19 1406 1423 1406 1424 0.94

14 18 0.0001 0.0082 16.9 0.4 3 23 1530 1550 1529 1550 0.98

15 18 0.0072 0.57 11.1 0.1 1 23 1585 1607 1585 1607 0.97

16 18 0.00084 0.067 14.0 0.6 2 23 1708 1730 1707 1730 0.93

17 18 0.0091 0.73 10.8 0.3 3 23 1786 1806 1786 1806 0.98

18 18 0.00013 0.01 16.6 4.5 1 23 2188 2210 2188 2210 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.4	32	5.6	1.0	3	23	501	522	500	522	0.93
2	18	0.5	40	5.3	3.2	3	22	629	648	627	648	0.89
3	18	0.00086	0.068	14.0	3.3	1	22	751	772	751	774	0.90
4	18	0.099	7.8	7.5	0.1	2	21	786	805	785	806	0.93
5	18	0.00099	0.079	13.8	0.2	2	23	938	960	937	960	0.95
6	18	0.0029	0.23	12.4	0.1	1	23	968	991	968	991	0.96
7	18	2.3e-05	0.0018	18.9	0.1	2	23	1077	1098	1076	1098	0.97
8	18	0.00041	0.033	15.0	2.9	2	23	1214	1236	1213	1236	0.97
9	18	0.032	2.6	9.1	0.2	2	23	1245	1267	1244	1267	0.95
10	18	0.0031	0.25	12.3	0.1	1	23	1280	1303	1280	1303	0.97
11	18	0.00018	0.014	16.2	1.1	1	23	1345	1367	1345	1367	0.99
12	18	0.0028	0.22	12.4	0.9	1	23	1375	1398	1375	1398	0.96
13	18	0.097	7.7	7.5	0.4	2	19	1406	1423	1406	1424	0.94
14	18	0.0001	0.0082	16.9	0.4	3	23	1530	1550	1529	1550	0.98
15	18	0.0072	0.57	11.1	0.1	1	23	1585	1607	1585	1607	0.97
16	18	0.00084	0.067	14.0	0.6	2	23	1708	1730	1707	1730	0.93
17	18	0.0091	0.73	10.8	0.3	3	23	1786	1806	1786	1806	0.98
18	18	0.00013	0.01	16.6	4.5	1	23	2188	2210	2188	2210	0.99

Sequence Information

Coding Sequence: ATGTCGCTTCTGTATCCAATTGCGATTTTGCCGCCATCATCGTCGCCACTTGAGAAAGAGATGTGCCCAACAGGACGTCGCTCTgcagatATCACGCCATTGGATCGCCTGTCGCTGCAAATTTGTCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGACGAAGCAGCGCCAATGGTTGGACATGGACAGAACCAAACAGCAGACGCTATTGGGCTACTTGGATTTGAATCGGGCCGAGAATGGCAGCATTGTTGaccatcagcaacagcaatctGAATTGAAAGTCGATACGGCAGTGTCTGCAGCTGAGAAGGCATCCGCTAACATTTTGGATGGCATACCCTCGCTGAAGAAGCGCAAATCGTTAACAGTCTATGTGAGTCCAAAGCAAcagcttcaacagcaacaacaacagcatcagcagcagcaacaacagcagcaactactACTGCAAACGGCAAGAACGATGGGCGGGGCAGCGGAGCCACAGCAAACATTGCAGAACCTTTTATTGCAGGTGCCCGTAACGGCGACAATGGCAACGATATcatcacagcagcaacagccacatcagacgcagcagcagcagcaacagcagcgcaaatatcagcagcaacaacaacgtggcAAGCAAAAACATCACCatcattatcagcaacaacaacaacaacaacatcatcatcaccatcatcatcatcagcaacaacagcagcaacatcaacaacaacaacagcgacgtAGACGCACTCGTCAGCCGCGACGAGAGTCGCAAcaagcagcaactgttgctcagCGTTTGACCAAATTTAAGCCAAAAGTATATTTGCCACTTGACATTTCAGTGCCACCGCTGCCGCCACTGTTGCCGACGTCAActtcaactgctgctgctgctgcagctgttaCTGCAActactgctgctgcaactgcaactgttgctgacGCATCTGCATCGTTatcgttgccattgccgttgtCGCAGCCAATTGATTTCAGCCAGTGTAAGAATTCGATTCAGAGTCAAGTATATGGCAGCGTGTTGCCCCCGCCTCCACCAGTTGCAACAGTGGGCAGCAACGTCGCTACAGCAACTGTCACTGCAACTGCTGGTCccgctgctactgctgctgcatctgtatctgccactgccactgcaacTGCTACCCCAGGCTCTGCTGCAGTCACAACTCCGCTGCTCATGCCGCCGCTGCCTGCCATGCCCATCAAGGATGAGCCATTGGATGACACGGACGATGACTTTCAGATGAAGTGCATTGACGAGTCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTGCCACTCATGACCTCCGAATATGATTATACGGCGCAGCATGGCGTGACGGCGGCCGTGGCAGCGGCATCGCTGCCACCAAGCGCTGTGGCCGCAGTGGCAGCCGCTGGGGACTCAAAAGTGGCCAGTTGCCGTGCCTGCAGTCTGCAGTTCTCGACCCGAGCGAATGCGCGACGCCACGAACGGAACTTGCATCCGAATCTGTTCCAGCTATCGACAGACTCGCCAAATAACACGCCAATCACAAAACCGACTCCGGCACTGGCAGCCGCATTGGAAATTCAACGTGCGGCCGCcgcggcagcggcaacagcggAGGCAACTAAAGCGGCAGCCGGCGGCAATATATCGACACAGAAGTACCGCCAAGTGGTCATGAATACGTTCATCAAGTGCGAGAACGGCGGCTATGACTACGACAATCCGGAGCAGTATCAGCAGCTGTTAAGTCGCGACAAAGTCGAGTTCATCCAGGAGAATAACGAGTTTCTCGAGCAATATCAAACGATGACGTGTCGATGTTGCAACAAATACTTTAGCACCTATAAGAACTTTATGGCGCACGTGCGCAAGAAGTATCCATTGTTGCCACGCAACCTGTGCTTCAATTGCCTCAAAATGAACGACTCCAAGGCGTTGTTCATATCGCATCTCAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCGTTGCGACTCAAACAGCCAAATTTTGCCCATGCCACATCATCCGGCGTGGTTGCAACCACTGAGccgccgcagcagcaacaacaacagcaacaacagcaacaattggtGCTAACATCGCATGAAACATCAACGTCAGAGCGACCGGAAAAGTTGCGGGCCAAGGAGCTGCTGGTGAATAAACTGTACGAGTGTAAGCTCTGTCCAAAGGGATTTCGCACGAAGCACGAGTTCCGCACACATGTCTATGATAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGATCGGCGACGTCACTACAATAACATGGACTGCATTGTCCGTTTGCGCTGCATGACCTGCGATGCCAAATTGGAGACGCATCAGCGTTTCCTCGACCATGTCTATCAGGATCATTTGGGCGGTGCCGTGAGCAGTGATAATGCCTCGACGGCCAACAGCGTCATCGATCATTCGCCGGGAAAGCGGAGTTTGCTCGGTGCCCTTGGCATTGGTGTGAGTCAATCCTCCAATGATGAAtcccgcagcagcagcaccaacaacaatgccCCAAATGCCCCAATAACTTCCACACCGAaactaccaacaacaacatcagtgattggagctgctgccgctgctgcaaCCAGCGGTGGTGGTGGCACCACATCCGGCAATCGAGATGCACCCAAATCCCAGTATTTCTCCCGCATGCCACAGGTCTGCCCCATTTGTGGCCAACAGTATAATAACTACAACAACGTGCTGCGCCACATGGAATCGAAGCATCCAAATAAACTGCCCGAGACATACAAGTGCGTCCGATGCGGCTTGGGCTATCCAAGGATCTCATATCTGCGCGAGCATATGATTAATGTGCATGGCGTGGACAAGAATCGTCATTCTGGCGGTTTTGAGTACATTGTGAATGCGGATGCCGTTAAATTGGCCGATGGCAGCACACCAAATGTCTACACTGGACGCTATGATTATGTGATGAAGGATTTGATGTCCATAACAAATGGTGGGACACtcgatgatgacgacgatgaagGCGGCAGCATTGCCAAAAAGATGCGACTCGAtgatagcagcaacaacagcagcattaACACCAGCATCGCCAATCAGCAGAAGGAGTGTCCCATTTGTAATGCCGTGTTTAGTAATAATATTGGATTATCGAATCATATGCGTTCACATTACACGGCCTCATCGACGGCAACAAATGCAGCATTGGCGGCTGCCAATCGAATGACGCCCAAGTCGTTGACAATTACAGCAACGCCGCCACTTGAGGTggcagccacagccacagcaacgacggtgacagcaacaacatcttCCTCCACCAGCAacgcagcagcatcagcagcagcaacaatggcGACGCCAATAAgcacaactgcaacagcaactacaataTCTGCGATAActgcaacgacaacaactaaaGTGCCACCGGCAATGGTAAATCAAACGCCACAGGAACAGGCCGTATTCCGTCGCAGTTTGGATCAAGCGGCGGATCGTCGCTTCCGTCGGATGCGTTGCCGCATCTGTCAGCGTAGATTCAGCTCGAAGAAGTCGTATCGCTATCATATGCTTACCGATCATCAGGTGCAAAATGTGCAGttcattaaatgcaaattgtgcAACGCCGAGTTTGCCTACGAGAAGGGATTGAAGGTGCATCTGTTCAAGGTGCACGGACGTGCCATCAAAGATGAGATGATTATCAAACAATTTGAATGTGATGTCTGCTCCATTGTCTACAGCTCTGAATTGGAGCTGCAGCAGCACAAACGCAGCGTTCACAAGTCACAATTGGGCTCAAAATCATTAgcattattatcatcatcatcatctacAGCTACTGCTACCTCTGGTGACCTGGCCGAAACATCCGCTAGTGCGTTAGCTGCCTTGCCATTGTATTGGTATCAGTGCAAGTATTGTCCATCTAACTTCAATACCAACAAGAAACTGGCCATCCACATCAATTCCCACGATGAGTTCGATTCCAATGATTATTCCTGCAAGGATTGTGGCAACGTCTACAGCGGACGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAGGTGCCGGACCCGGCGGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCACACCCCCACCTGCAATCGGAAGCCCATTACGGCGACGGGAGCACATCAGCAggatcaacagcagcagcagcaacaacagttgcaattgcaacagcagcgTGGCATATTCAAGCACAAGACGGGCGACGATGACGAAGAGGACGACGATGAcgagcagctgcagcatcAAATGATGTTAGATGATGCTGCTGGGGCTGGTGTTGGTGCTGGCAATCTTGCCAGCGATGGCAGCAATGGTGGCAACACTGTGGCAGCTGTTGCAAGCAACACAAACACGATCAGTACAAGCAGCTTTAAGATACGCATACCAGAGGTGGCATGCACCATTTGTGGGGCACGTTTCACCGATCAAGAGATGTTCAGCAAGCACATCCAGAAGCATGAACAGGAGCTATATGTGGACAATCCATTGGCAGCCATGTTCGATGATGGTCCAGCCGATGCGGGACAATTTCAGGTGGAGCGTCAAAATGAGAATGGGGAATATGCGTGCGATTTGTGTGCAAAGACTTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAATGctgaacaacaacaccaacaacaacaacaacagcagcagcaccaccagcagcaacagcaattcgATGTTGCATCTACGCGAGTTGCATGCGGTGGGTCTGATGcccaatcaacaacaacaccagaagcagcagcaacagctgcaacagcaacaacaacaacagtctcagtcgagcagcaacaacagcaacaacaacaacaccagcaacagctCATCGACCAGCAAATCGATGAAACGGAAACGTGAATTGAAATGCGAATATTGTGCCTCAACATtcattagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAGCATGAGGTCAGCAATCTTCCCGAGCCGCCAGTGATTGAAGTGGATGAGCCGCTGTGTTGTCGTCGTTGCGGCGATTTACAATTTGAGACCAAGGAATTGTGGATCGAACACAAATTGGCGGATGCAAAGGTGGTGCGTCCATTTTGTCCATTCCAATGGGGCTGTGATCTTTGTGGCGAGTATTTGTCGCGTAAGGAGAAGCTCATCAATCACATTAACAATCATCTAAAGGAGGAGGTAATTGTGCCAGTTGCCAATGCAAAGACAACAATCAACTCGTcagaggcaacaacagcaacagctaaaagcccaacaacgacgacagcaacaacggcaaacTCAACAACTGgtggagcagctgcagcagcaacaactgcaactggaactgcaactgcagTCAAAGAGCAACAGGAAGAGGAAGATGAGGATGATAGTGAgatggatgatgatgatagcGAAAGCGAtggcgatgatgatgaggaggaggacgaTGATGAGGAGAATAGCACaagcgatgatgatgatgacgatgatgatgtcgACGATgaagatgacgatgatgacgatgaagaGGAGGATGTTGTtgcaaaacagcagcaactgttgcaacaACCTCAGCAACAGccaaataacagcaacagcaacaatagcaacaacagcaatgcaaTTGACAACGATGATGACGATCTGATTGAGGAGGTTATCGAAGAGAttgatgatgacgatggcgatggcgatgtgCATGAACAACATGTTGCCAGAGCaaacgccaacaacaataaagtcaACATTGACTATACGCGCACGGGCAACGCCAAGTTGAATGGAAATGGTGGCAAAAAGGCAAAGTTGCAACATGGGCAAGTGCTGATCATGCATAGCTccgaggaagaagaagaagaagaagacgatgtagatgatgatgatgatgtggaaatggaaatggcagAGGCCGAAGAGGATGATGAAGAGGGCGTACACGTAGGAGATGTGATGACCATTGATGATATTATTGAAGAAGATGATGGTGAGGATGATGACGATGTGGTTGGTGTTAGTGGTGAAGTTGTTGAAgaggatgatgatgttgaCAACGACGATCgtgatcatgatgatgatgttgatgatgaagaggaggaggaagatGAAGATATCGatgaagacgacgacgacgacgatgatgacgatggcGATGGTGGCGATCGTCGTAATCGTGTTGATGGTGctggtgatggtgatggtgatggtaCATCATCATCCGAGAGCGAGTCGACAACGACTACCTCGCATTCAACTGGTGAGCGGCGTAAAAAAACTGTAGTTTCATCAGCGGCACATGGCGATGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCATCTGCAAACACACATTAAAAGCCATTTTCTCAATGGGCCAATGGCGGGCGTCAAGAGCAAgaacaacggcagcagcagcagcagcagtggcagcaacaacaacaacagcagcaacggcagcagcagcaacaacaacaacaataacaacaataataatagcaacatcaataataaaagcaaaaccaaaaagtccGACTTGTTGGATGCTACAAAatgtggcggtggcggtggcagtacaacaaccacagcaacagccacagcagcagcaacaacaacggcaacaacaacgacgtcaacgtcagcagcgactgcgacagcgGAAGATGCGGCAGCGAGCTTGAACTGA
Protein Sequence: MSLLYPIAILPPSSSPLEKEMCPTGRRSADITPLDRLSLQICHACISYLNSWQSFKNRCLSSQTKQRQWLDMDRTKQQTLLGYLDLNRAENGSIVDHQQQQSELKVDTAVSAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQHQQQQQQQQLLLQTARTMGGAAEPQQTLQNLLLQVPVTATMATISSQQQQPHQTQQQQQQQRKYQQQQQRGKQKHHHHYQQQQQQQHHHHHHHHQQQQQQHQQQQQRRRRTRQPRRESQQAATVAQRLTKFKPKVYLPLDISVPPLPPLLPTSTSTAAAAAAVTATTAAATATVADASASLSLPLPLSQPIDFSQCKNSIQSQVYGSVLPPPPPVATVGSNVATATVTATAGPAATAAASVSATATATATPGSAAVTTPLLMPPLPAMPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSEYDYTAQHGVTAAVAAASLPPSAVAAVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLSRDKVEFIQENNEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFAHATSSGVVATTEPPQQQQQQQQQQQLVLTSHETSTSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGAVSSDNASTANSVIDHSPGKRSLLGALGIGVSQSSNDESRSSSTNNNAPNAPITSTPKLPTTTSVIGAAAAAATSGGGGTTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDDEGGSIAKKMRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTATNAALAAANRMTPKSLTITATPPLEVAATATATTVTATTSSSTSNAAASAAATMATPISTTATATTISAITATTTTKVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSIVYSSELELQQHKRSVHKSQLGSKSLALLSSSSSTATATSGDLAETSASALAALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQLQLQQQRGIFKHKTGDDDEEDDDDEQLQHQMMLDDAAGAGVGAGNLASDGSNGGNTVAAVASNTNTISTSSFKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATMLNNNTNNNNNSSSTTSSNSNSMLHLRELHAVGLMPNQQQHQKQQQQLQQQQQQQSQSSSNNSNNNNTSNSSSTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLCCRRCGDLQFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEEVIVPVANAKTTINSSEATTATAKSPTTTTATTANSTTGGAAAAATTATGTATAVKEQQEEEDEDDSEMDDDDSESDGDDDEEEDDDEENSTSDDDDDDDDVDDEDDDDDDEEEDVVAKQQQLLQQPQQQPNNSNSNNSNNSNAIDNDDDDLIEEVIEEIDDDDGDGDVHEQHVARANANNNKVNIDYTRTGNAKLNGNGGKKAKLQHGQVLIMHSSEEEEEEEDDVDDDDDVEMEMAEAEEDDEEGVHVGDVMTIDDIIEEDDGEDDDDVVGVSGEVVEEDDDVDNDDRDHDDDVDDEEEEEDEDIDEDDDDDDDDDGDGGDRRNRVDGAGDGDGDGTSSSESESTTTTSHSTGERRKKTVVSSAAHGDAADQSNSSYTCDLCQLCFDSQEHLQTHIKSHFLNGPMAGVKSKNNGSSSSSSGSNNNNSSNGSSSNNNNNNNNNNSNINNKSKTKKSDLLDATKCGGGGGSTTTTATATAAATTTATTTTSTSAATATAEDAAASLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575750;
90% Identity: iTF_00533987;
80% Identity: -