Basic Information

Insect: Drosophila limbata
Gene Symbol: hang
Assembly: GCA_963924055.1
Location: OZ001351.1:12190079-12203871[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.38 39 5.6 1.0 3 23 507 528 506 528 0.93

2 18 0.48 49 5.3 3.2 3 22 635 654 633 654 0.89

3 18 0.00082 0.083 14.0 3.3 1 22 756 777 756 779 0.90

4 18 0.095 9.6 7.5 0.1 2 21 791 810 790 811 0.93

5 18 0.00095 0.096 13.8 0.2 2 23 939 961 938 961 0.95

6 18 0.0027 0.28 12.3 0.1 1 23 969 992 969 992 0.96

7 18 2.2e-05 0.0022 18.9 0.1 2 23 1078 1099 1077 1099 0.97

8 18 0.00039 0.04 15.0 2.9 2 23 1219 1241 1218 1241 0.97

9 18 0.031 3.1 9.0 0.2 2 23 1250 1272 1249 1272 0.95

10 18 0.0011 0.11 13.6 0.2 1 23 1285 1308 1285 1308 0.97

11 18 0.00017 0.017 16.1 1.1 1 23 1348 1370 1348 1370 0.99

12 18 0.0027 0.27 12.4 0.9 1 23 1378 1401 1378 1401 0.96

13 18 0.093 9.4 7.5 0.4 2 19 1409 1426 1409 1427 0.94

14 18 9.9e-05 0.01 16.9 0.4 3 23 1527 1547 1526 1547 0.98

15 18 0.0069 0.7 11.1 0.1 1 23 1582 1604 1582 1604 0.97

16 18 0.00081 0.082 14.0 0.6 2 23 1698 1720 1697 1720 0.93

17 18 0.0088 0.89 10.8 0.3 3 23 1776 1796 1776 1796 0.98

18 18 9.2e-05 0.0093 17.0 2.1 1 23 2210 2232 2210 2232 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.38	39	5.6	1.0	3	23	507	528	506	528	0.93
2	18	0.48	49	5.3	3.2	3	22	635	654	633	654	0.89
3	18	0.00082	0.083	14.0	3.3	1	22	756	777	756	779	0.90
4	18	0.095	9.6	7.5	0.1	2	21	791	810	790	811	0.93
5	18	0.00095	0.096	13.8	0.2	2	23	939	961	938	961	0.95
6	18	0.0027	0.28	12.3	0.1	1	23	969	992	969	992	0.96
7	18	2.2e-05	0.0022	18.9	0.1	2	23	1078	1099	1077	1099	0.97
8	18	0.00039	0.04	15.0	2.9	2	23	1219	1241	1218	1241	0.97
9	18	0.031	3.1	9.0	0.2	2	23	1250	1272	1249	1272	0.95
10	18	0.0011	0.11	13.6	0.2	1	23	1285	1308	1285	1308	0.97
11	18	0.00017	0.017	16.1	1.1	1	23	1348	1370	1348	1370	0.99
12	18	0.0027	0.27	12.4	0.9	1	23	1378	1401	1378	1401	0.96
13	18	0.093	9.4	7.5	0.4	2	19	1409	1426	1409	1427	0.94
14	18	9.9e-05	0.01	16.9	0.4	3	23	1527	1547	1526	1547	0.98
15	18	0.0069	0.7	11.1	0.1	1	23	1582	1604	1582	1604	0.97
16	18	0.00081	0.082	14.0	0.6	2	23	1698	1720	1697	1720	0.93
17	18	0.0088	0.89	10.8	0.3	3	23	1776	1796	1776	1796	0.98
18	18	9.2e-05	0.0093	17.0	2.1	1	23	2210	2232	2210	2232	0.99

Sequence Information

Coding Sequence: ATGTCGCCTCTGTATCCAATTGCGATTTTGCCGCCATCATCGTCGCCACTTGAGAAAGAGATGTGCCCAACAGGACGTCGCTGTgcagatgtgtgtATCACGCCATTGGATCGCCTGTCGCTGCATATTTGTCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGTCGAAGCAGCGCCAATGGGTGGACATGGACAGAACCAAACAGCAGACACTATTGGGCTATTTGGATTTGAATCGGGCCGAGAATGGCAGCATTGtcgagcaacagcagcagcaatctgaaTTGAAAATCGATACGGCAACATCTGCAGCTGAGAAGGCATCCGCTAACATTTTGGATGGCATACCCTCGCTGAAGAAGCGCAAATCGTTAACAGTCTATGTGAGTCCAAagcaacagcttcaacagcaacaacaacaacagcagcagcagcagcagcagcaacaacaactactactgCAAACGGCAAGAACGATGGGCGGGGCAGCGGAGCCACAGCAGACATTGCAGAACCTTTTATTGCAGGTTCCCTTAACGGCGACAATGGCAACGATATcatcacagcagcaacatcagcagcaacagcagcagcaacagcagcgaaaatatcagcaacaacaacaacgtggcAAGCAAAGACATCACCATcattatcaacaacaacaacaacatcatcatcatcatcaccatcatcaacagcaacaacagcagcaacatcaacaacaacagcagcgacatAGGCGCACTCGTCAGCCGCGACGACAGTCGCAACAgacagcaactgttgctcaGCGTTTAACCAAATTTAAGCCAAAAGTGTATTTGCCACTTGACATTACAGTGCCACCGCTGCCGCCACTGCTGCCGACGTCAACTTCGactgctgctgcgactgcaactgcaactactgctactgctgctggtgttgctgaGGCAGCTGCATCGTTatcgttgccgttgccgttgccgttgtcgcAGCCAATTGATTTTAGCCAGTGTAAGAATTCGAGTCAGAGTCAAAGATATGGCAGCGTGTTGCCTCCGCCGCCACCAGTTGCAACAATGGGCAGCAACGTCGCTACAGCATCTGCGACAGCAACTGCTGCTCCCGCtcccgctgctgctgcatctgTATCGGTatctgccactgccactgctaCTGTCACTGCCTCAGGCTCAAGCTCAGGCTCTGCTGCAGTCACAACTCCGCTGCTCATGCCGCCGCTGCCTGCCATGCCCATCAAGGATGAGCCATTGGATGACACGGACGACGACTTTCAGATGAAGTGCATTGACGAGTCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGGCCTCCGACTATGATTATACGGCGCAGCATGGCGTGACGGCGGCTGTGGCAGCAGCATCGCTGCCGCCGACCGCTGTGGCAAATGTGGCAGCCGCTGGAGACTCGAAGGTGGCCAGTTGCCGAGCCTGCAGTCTGCAGTTCTCGACCCGAGCGAATGCGCGACGCCACGAACGCAACTTGCATCCGAATCTGTTCCAGCTATCGACAGACTCGCCAAATAATACGCCAATCACAAAGCCGACGCCGGCACTGGCAGCCGCATTGGAAATTCAACGTGCGGCCGCCgcggcagcggcaacagcggAGGCAACAAAGGCGGCAGCCGGCGGCAACATATCGACACAGAAGTACCGCCAGGTGGTCATGAATACGTTCATCAAGTGCGAGAACGGCGGCTATGACTACGACAATCCGGAGCAGTATCAGCAATTGCTGAGCCGCGACAAAGTCGAGTTCATCCAGGAGAATAACGAGTTTCTAGAACAATATCAAACGATGACGTGTCGATGTTGCAACAAATACTTTAGCACCTATAAGAACTTTATGGCGCACGTGCGCAAGAAGTATCCATTGCTGCCACGCAACCTGTGCTTCAATTGCCTCAAGATGAACGACTCCAAGGCGTTGTTCATATCGCATCTCAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCGCTGCGACTCAAACAGCCAAATTTTGCCCATGCCACGTCATCCGGTGTGGTTGCAACCACTGAGCCGCCGCAGCAATtgccgcagcaacaacaacaacaattggtgGTAACATCACATGAAACATCAACGTCGGAGCGGCCGGAGAAGTTGCGAGCCAAGGAGCTGCTGGTGAATAAACTGTACGAGTGTAAGCTCTGTCCGAAGGGATTTCGCACGAAGCACGAATTCCGCACACATGTCTATGATAAGCATGCGGATGTGCAGCGCAAGGATAACAACTCGATACAGTGCAGCTTCTGTGGGCTGGACTTTGCCGATCCGGTTGATCGGCGACGTCATTACAATAACATGGACTGCATTGTCCGGCTGCGCTGCATGACCTGCGATGCCAAATTGGAGACGCATCAGCGTTTCCTCGACCATGTCTATCAGGATCATTTGGGCGGTGCCGTGAGCAGTGATAATGCCTCGACAGCCAACAGCGGCATCGATCATTCGCCGGGGAAGCGGAGTCTCCTCGGTGCCCTTGGCATTGGTGTGAGTCAATCCTCCAATGATGAAtcccgcagcagcagcaccaacaacaatgccgCAAATGCACCAATAACTTCCACACCGAaactaccaacaacaacatcagcgaTTGGAGCTGCTGCAGCAACCAGTGGTGGCTCCACATCTGGCAGTCGAGATGCACCCAAATCCCAGTATTTCTCCCGCATGCCACAGGTCTGCCCCATTTGCGGCCAACagtacaacaactacaacaacgtGCTGCGCCACATGGAATCGAAACATCCAAATAAACTGCCCGAGACATACAAGTGCGTTCGATGCGGCTTGGGCTATCCAAGGATCTCATATCTGCGCGAGCATATGATCAATGTGCATGGCGTGGACAAGAATCGTCATTCCGGCGGATTTGAGTACATTGTTAACGCGGATGCCGTTAAATTGGCCGATGGCAGCACACCAAATGTCTACACTGGACGCTACGATTATGTGATGAAGGATTTGATGTCCATAACAAATGGTGGGACACtcgatgatgatgaggatgaaGGCGGCAGCATTGCCAAAAAGATGCGACTCGAcgatagcagcaacaacagcagcatcaacacaAGCATCGCCAATCAGCAGAAGGAGTGTCCCATTTGTAATGCCGTGTTTAGTAATAATATTGGATTATCGAATCACATGCGTTCACATTACACGGCCTCATCGACGGCAACAAATGCAGCATTGGCGGCTGCCAATCGAATGACGCCCAAGTCGTTGACAATTACAGCAACGCCGCCACTTGAGGTGGCAGTCACAGCCACAGCAACGAcggcgacagcaacaacatcttCCTCCACAAGCAacgcagctgcagcagcagcagcagcaggaacaacagcaacgccAGTGAgcacaactgcaacagcaacagcaactgcaataTCTGCGATAActgcaacgacaacaactaaAGTGCCACCGGCAATGGTAAATCAAACGCCACAGGAACAGGCCGTATTCCGTCGCAGTTTGGATCAAGCGGCGGATCGTCGCTTCCGTCGGATGCGTTGCCGCATCTGTCAGCGTAGATTCAGCTCGAAGAAGTCGTATCGCTATCACATGCTGACCGATCATCAGGTGCAGAATGTGCAGTTCATCAAATGCAAGTTGTGCAACGCCGAGTTTGCCTACGAGAAGGGATTGAAGGTGCATCTCTTCAAGGTGCACGGACGTGCCATCAAAGATGAGATGATTGTCAAACAATTTGAATGTGATGTCTGCTCCATTGTGTACAGCTCTGAAATGGAGCTGCAGCAGCACAAACGCAGCGTTCACAAGTCACAATTGGGCCCGAAATCATTAGCATTATTATCATCATCTACAGCTACTGCTACCTCTGCTGACCTGGCCGAAACATCCGCTAGTGCGTTAGCTGCCCTGCCCTTGTATTGGTATCAGTGCAAGTATTGTCCATCCAACTTTAATACCAACAAGAAACTGGCCATTCACATCAATTCCCATGATGAGTTCGATTCCAATGATTATTCCTGCAAGGATTGTGGCAACGTCTACAGCGGACGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAGGTGCCGGACCCGGCGGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCACACTCCCACCTGCAATCGCAAGCCCATAACGGCGACGGGGGCACATCAGCAggatcaacagcagcagcaacatttgcaattgcaacagcAGCGTGGCATATTCAAGCACAAGACGGGCGACGATGACGAAGAGGACGAGGATGAcgagcagctgcagcatcaGATGATGTTAGATGATGCTGCCGGTGCTGGCAATGCTGCAAGTGACGGCAGCAATGGTGGCAACACTGTGGCAGCTGTCGCAAGCAATACGAACACGATCAGTACAAGCAGCTTTAAGATTCGCATACCAGAGGTGGCATGCACCATTTGTGGGGCACGTTTCACCGATCAAGAGATGTTCAGCAAGCACATCCAAAAGCATGAACAAGAGCTATATGTGGACAATCCATTGGCAGCGATGTTCGATGATGGTCCAGCCGATGCGGGACAATTTCAGGTGGAGCGTCAAAATGAGAATGGGGAATATGCGTGCGATTTGTGCGCAAAGACTTTCCCCCAGGTGATTGCGCTAAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAATGCtgaacaacaacaccaacaacaacaacaacagcagcagcaacagcaattcgaTGTTGCATCTACGCGAGTTGCATGCGGTGGGTCTGATGcccaatcaacaacaacaccagaagcagctgcagctgcaacaacaacaacaacagtctcagtcgagcagcaacaacaacaacaacaacaccagcaacagctCATCGACCAGCAAATCGATGAAACGGAAACGTGAATTGAAATGCGAATATTGTGCCTCAACATtcattagcaacaacaacctgCGTCGCCACATGTACGAGCTGCACAAACATGAGGTCAGCAATCTTCCCGAGCCGCCAGTGATTGAAGTGGATGAGCCGCTGTGCTGTCGTCGTTGCGGCGATTTACAATTTGAGACCAAGGAATTGTGGATCGAACACAAATTGGCGGATGCTAAGGTGGTGCGTCCATTTTGTCCATTCCAATGGGGCTGTGATCTTTGTGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATTAATCACATTAACAATCATCTCAAGGAGGAGGTAATTGTGCCAGTTGCCAATGCAAAGAcagaggcagcaacagcaatagctAAAAgcacaacaacgacgacagcaacaacagcaaaggcaacaactggtgaagcagctgcagcaacaacaacaacaacaactgcaactgaaacaacaacagcaggcaaAGGGCTAAAAGTCAAAGAGATTGAAAGCGAGAGAGACGGAAAGTTGAGCAAATCGCGTGCTAATGATAATGTAGTGCAAcaggaagaggaagaagaggaTGATAGTGATATGGATGATGATAGCGATagcgatgacgatgatgatgatgaggaggatgatgatgaggagAATAGCACaagcgatgatgatgacgatgatgatgtcGACGATGAGGATGACGATGAAGacgatgaagatgaagatgttgttgcaaaacagcagcaactgttgcaacaACCTCAACAACAgccaaacaacagcaacaacaacaatagcagcaacagcaatgcaATTGACAACGATGATGACGATCTCATTGAGGAAGTTATCGAAGAGAttgacgatgacgatggcgATGGGGACGGGGATGCCGAAGTGCATGAACAACATGTTGTTGCCAGAGCAAacgcaaacaacaataaagtcAACATTGATTATACGCGCACGGGCAACGCCAAGTTAAATGGGAATGGTGGCAAAAAGGCAAAGTTGCAGCACGGGCAAGTGCTGATCATGCATAGCTccgaggaagaagaagaggatgtcgatgatgatgatgtggaaatggaaatggcagaggcagaggcagaagaGGAGGATGAAGAGGGTGTACACGTGGGGGAAGTAATGACCATTGATGATATTATTGAAGAAGATGATGGTGAGGATGATGACGATGTGGTTGGTGTTAGTGGTGAAGTTGTTGaagaggatgatgatgatgacaacgACAATGATAACGACGATCgtgatcatgatgatgatgttgatgaggaagaggaggaagaTGAAGATATCGATGaagacgacgatgacgatggcgACGTTGATGTGGGCAATGGTCGTCGTAATCGTGTTGATGGTGGTCGTGTCAACATCGGTGATGCtggtgatggtgatggtgatggtACATCATCATCCGAGAGCGAGTCGACAACGACAACCTCGCATTCAACTGGTGAGCGGCGTAAAAAAACTGTAGTTTCATCAGCGGCACATGGCGATGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTGCAGACACACATTAAAAGCCATTTTCTCAATGGGCCAATGGCGGGCTTCAAGAGcaagaacagcagcagcagcaggagcagcagtggcagcaacaccagcagcagcagcagcggagGCGCCGCCAgtagaagcaacaacaacaacaataataataatagcaacaacaataataaaagcaaaaccaaaaagTCCGTCTTGTTGGATACTACAAaatgtggcagtggcagtggcagtggcagtggcagtacaacaaccacagcaacagccacagcagcagcaacaacaacggcagcaacaacgacgtcgacgtcagcagcgactgcgacagcgGGAGATGCTGCAGCGAGCTTGAACTGA
Protein Sequence: MSPLYPIAILPPSSSPLEKEMCPTGRRCADVCITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWVDMDRTKQQTLLGYLDLNRAENGSIVEQQQQQSELKIDTATSAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQQQQQQQQQQLLLQTARTMGGAAEPQQTLQNLLLQVPLTATMATISSQQQHQQQQQQQQQRKYQQQQQRGKQRHHHHYQQQQQHHHHHHHHQQQQQQQHQQQQQRHRRTRQPRRQSQQTATVAQRLTKFKPKVYLPLDITVPPLPPLLPTSTSTAAATATATTATAAGVAEAAASLSLPLPLPLSQPIDFSQCKNSSQSQRYGSVLPPPPPVATMGSNVATASATATAAPAPAAAASVSVSATATATVTASGSSSGSAAVTTPLLMPPLPAMPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMASDYDYTAQHGVTAAVAAASLPPTAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLSRDKVEFIQENNEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFAHATSSGVVATTEPPQQLPQQQQQQLVVTSHETSTSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGAVSSDNASTANSGIDHSPGKRSLLGALGIGVSQSSNDESRSSSTNNNAANAPITSTPKLPTTTSAIGAAAATSGGSTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEDEGGSIAKKMRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTATNAALAAANRMTPKSLTITATPPLEVAVTATATTATATTSSSTSNAAAAAAAAGTTATPVSTTATATATAISAITATTTTKVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSEMELQQHKRSVHKSQLGPKSLALLSSSTATATSADLAETSASALAALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQHLQLQQQRGIFKHKTGDDDEEDEDDEQLQHQMMLDDAAGAGNAASDGSNGGNTVAAVASNTNTISTSSFKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATMLNNNTNNNNNSSSNSNSMLHLRELHAVGLMPNQQQHQKQLQLQQQQQQSQSSSNNNNNNTSNSSSTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLCCRRCGDLQFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEEVIVPVANAKTEAATAIAKSTTTTTATTAKATTGEAAAATTTTTTATETTTAGKGLKVKEIESERDGKLSKSRANDNVVQQEEEEEDDSDMDDDSDSDDDDDDEEDDDEENSTSDDDDDDDVDDEDDDEDDEDEDVVAKQQQLLQQPQQQPNNSNNNNSSNSNAIDNDDDDLIEEVIEEIDDDDGDGDGDAEVHEQHVVARANANNNKVNIDYTRTGNAKLNGNGGKKAKLQHGQVLIMHSSEEEEEDVDDDDVEMEMAEAEAEEEDEEGVHVGEVMTIDDIIEEDDGEDDDDVVGVSGEVVEEDDDDDNDNDNDDRDHDDDVDEEEEEDEDIDEDDDDDGDVDVGNGRRNRVDGGRVNIGDAGDGDGDGTSSSESESTTTTSHSTGERRKKTVVSSAAHGDAADQSNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPMAGFKSKNSSSSRSSSGSNTSSSSSGGAASRSNNNNNNNNSNNNNKSKTKKSVLLDTTKCGSGSGSGSGSTTTTATATAAATTTAATTTSTSAATATAGDAAASLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575750;
90% Identity: iTF_00585359;
80% Identity: -